Recent advances in the treatment of advanced renal cell carcinoma: towards multidisciplinary personalized care.

abstract：OBJECTIVE:To accurately define the anatomy of the neurovascular bundle (NVB) in men. MATERIALS AND METHODS:The NVB was microdissected in detail bilaterally in 12 fixed human male adult cadavers. The anatomy of the NVB and its relationship to surrounding pelvic structures was ascertained in each specimen. RESULTS:Prev...

journal_title：BJU international

authors： Costello AJ,Brooks M,Cole OJ

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:• To evaluate the safety and efficacy of once-daily trospium chloride extended release (ER) in overactive bladder syndrome (OAB) in subjects aged ≥ 75 years. SUBJECTS AND METHODS:• The analysis included subjects ≥ 75 years of age with OAB. • A subgroup analysis of pooled data was performed for subjects aged ...

journal_title：BJU international

authors： Sand PK,Johnson Ii TM,Rovner ES,Ellsworth PI,Oefelein MG,Staskin DR

更新日期：2011-02-01 00:00:00

abstract：:Androgen-deprivation therapy (ADT) is an effective treatment for men with advanced prostate cancer, but loss of bone mineral density (BMD) is a major risk factor for fractures. This review compared the efficacy of available treatments to provide prescribing guidance to healthcare professionals. This is the first revie...

journal_title：BJU international

authors： Poon Y,Pechlivanoglou P,Alibhai SMH,Naimark D,Hoch JS,Papadimitropoulos E,Hogan ME,Krahn M

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: For patients who are unfit for extirpative surgery, percutaneous cryoablation (PCA) presents a minimally-invasive alternative for the treatment of renal masses. PCA has been demonstrated to be safe, with complication rates <10% being reported consist...

journal_title：BJU international

authors： Kim EH,Tanagho YS,Bhayani SB,Saad NE,Benway BM,Figenshau RS

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To explore whether a panel of kallikrein markers in blood: total, free and intact prostate-specific antigen (PSA) and kallikrein-related peptidase 2, could be used as a non-invasive alternative for predicting prostate cancer on biopsy in a screening setting. SUBJECTS AND METHODS:The study cohort comprised pr...

journal_title：BJU international

authors： Carlsson SV,Peltola MT,Sjoberg D,Schröder FH,Hugosson J,Pettersson K,Scardino PT,Vickers AJ,Lilja H,Roobol MJ

更新日期：2013-09-01 00:00:00

abstract：UNLABELLED:Study Type--Clinical (prospective trial) Level of Evidence 2b. What's known on the subject? and What does the study add? In clinical practice, we know that it is necessary to identify new biomarkers that can better detect prostate cancer (PC), at the same time as reducing the number of unnecessary biopsies. ...

journal_title：BJU international

authors： Sciarra A,Panebianco V,Cattarino S,Busetto GM,De Berardinis E,Ciccariello M,Gentile V,Salciccia S

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To investigate whether ageing and diabetes alter the expression of the gap junction protein connexin43 (Cx43) and of particular purinoceptor (P2R) subtypes in the corpus cavernosum and urinary bladder, and determine whether changes in expression of these proteins correlate with development of erectile and bla...

journal_title：BJU international

authors： Suadicani SO,Urban-Maldonado M,Tar MT,Melman A,Spray DC

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To determine the safety, efficacy and pharmacokinetics of tolterodine in children with an overactive bladder. PATIENTS AND METHODS:Thirty-three children (20 boys and 13 girls, aged 5-10 years) with an overactive bladder and symptoms of urgency, frequency and/or urge incontinence were enrolled in an open, dos...

journal_title：BJU international

authors： Hjälmås K,Hellström AL,Mogren K,Läckgren G,Stenberg A

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To present the results of endopyelotomy using endoluminal ultrasonography (EUS) to identify crossing vessels, as the success rates of endopyelotomy are generally lower than pyeloplasty, especially in patients with crossing vessels. PATIENTS AND METHODS:Forty-one consecutive patients who underwent EUS before ...

journal_title：BJU international

authors： Parkin J,Evans S,Kumar PV,Timoney AG,Keeley FX Jr

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To examine differences in gene expression levels between renal cell carcinoma (RCC) tissue and 'normal' appearing renal tissue using a commercially available DNA macroarray. MATERIALS AND METHODS:Tissue was obtained from 47 consecutive radical nephrectomies, 29 of which were eligible. DNA macroarrays were an...

journal_title：BJU international

authors： Lovisolo JA,Casati B,Clerici L,Marafante E,Bono AV,Celato N,Salvadore M

更新日期：2006-07-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (outcomes) Level of Evidence 2a. What's known on the subject? and What does the study add? Erectile dysfunction (ED) is a well known implication of radical prostatectomy (RP). Despite the search for technical improvement in the surgical procedure (e.g. nerve-sparing surgery, robot-assiste...

journal_title：BJU international

authors： Polito M,d'Anzeo G,Conti A,Muzzonigro G

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To optimise the diagnostic and phototherapeutic efficacy of hypericin in superficial bladder cancer, by developing a bladder instillation fluid that does not depend on the presence of plasma proteins for an appropriate and reliable urothelial uptake of hypericin. MATERIALS AND METHODS:Sodium hypericinate (in...

journal_title：BJU international

authors： Huygens A,Kamuhabwa AR,van Cleynenbreugel B,van Poppel H,Roskams T,de Witte PA

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To relate the repeat length of the androgen-receptor CAG trinucleotide to the age of onset of prostate cancer, stage and grade of disease. PATIENTS AND METHODS:After obtaining ethical approval, 265 patients with locally confined or locally advanced/metastatic prostate cancer were identified and evaluated for...

journal_title：BJU international

authors： Mir K,Edwards J,Paterson PJ,Hehir M,Underwood MA,Bartlett JM

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...

journal_title：BJU international

authors： Hanna MY,Tremlett C,Josan G,Eltom A,Mills R,Rochester M,Livermore DM

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To determine the outcome 10 years after an individual course of pelvic floor muscle (PFM) exercises for genuine stress incontinence. PATIENTS AND METHODS:Postal questionnaires were sent to 52 women who had undergone PFM training 10 years earlier, and their medical files were reviewed. The main outcome measur...

journal_title：BJU international

authors： Cammu H,Van Nylen M,Amy JJ

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To determine if the biochemical composition of a renal calculus can be measured from 'dust' obtained during laser fragmentation. PATIENTS AND METHODS:This pilot study was set in a tertiary referral hospital between 2011 and 2013. Stone dust was aspirated through the ureteroscope during lasering and a stone f...

journal_title：BJU international

authors： Ray ER,Rumsby G,Smith RD

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To aid the interpretation of the trends in prostate cancer mortality, which declined in the UK in the early 1990 s for unknown reasons, by investigating prostate cancer death rates, incidence and treatments in England and Wales in 1975-2004. METHODS:Join-point regression was used to assess secular trends in ...

journal_title：BJU international

authors： Hussain S,Gunnell D,Donovan J,McPhail S,Hamdy F,Neal D,Albertsen P,Verne J,Stephens P,Trotter C,Martin RM

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of commercially available single-layer small intestinal submucosa (SIS) for urethral replacement, both as an onlay and as a tube, in a rabbit model. MATERIALS AND METHODS:Thirty-six male rabbits were assigned to four experimental groups. Group 1 had the ventral wall of the penile urethra ...

journal_title：BJU international

authors： El-Assmy A,El-Hamid MA,Hafez AT

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To better understand the genital changes that occur during the female sexual response, using a gross anatomical and histological study of the vascular tissue of the vulva, supplemented with magnetic resonance imaging (MRI). MATERIALS AND METHODS:Seven cadaveric vulvectomy specimens were used; they were seria...

journal_title：BJU international

authors： Yang CC,Cold CJ,Yilmaz U,Maravilla KR

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To present the outcomes of cT3N0M0 prostate cancer after radical prostatectomy (RP) and determine the prognostic factors in biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS), cancer-specific survival (CSS) and overall survival (OS) after long-term follow-up of 10 years. ...

journal_title：BJU international

authors： Hsu CY,Wildhagen MF,Van Poppel H,Bangma CH

更新日期：2010-06-01 00:00:00

abstract：:Three-dimensional (3D) printing or additive manufacturing is a new technology that has seen rapid development in recent years with decreasing costs. 3D printing allows the creation of customised, finely detailed constructs. Technological improvements, increased printer availability, decreasing costs, improved cell cul...

journal_title：BJU international

authors： Chen MY,Skewes J,Desselle M,Wong C,Woodruff MA,Dasgupta P,Rukin NJ

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To determine the adequacy of T2 prostate cancer (PCa) sub-staging as an independent Predictor of biochemical disease-free survival (bDFS) after radical prostatectomy. MATERIALS AND METHODS:The Duke Prostate Center database was queried for patients who underwent radical prostatectomy between 1988 and 2007 and...

journal_title：BJU international

authors： Caso JR,Tsivian M,Mouraviev V,Polascik TJ,Moul JW

更新日期：2010-12-01 00:00:00

abstract：UNLABELLED:Treatment options for testis cancer depend on the histological subtype as well as on the clinical stage. An accurate staging is essential for correct treatment. The 'golden standard' for staging purposes is CT, but occult metastasis cannot be detected with this method. Currently, parameters such as primary t...

journal_title：BJU international

authors： Ruf CG,Linbecker M,Port M,Riecke A,Schmelz HU,Wagner W,Meineke V,Abend M

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To systematically review the literature regarding clinical outcomes of 180-W XPS GreenLight laser (GL) vaporisation for the treatment of lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). METHODS:Recent publications were identified in the field of 180-W GL vaporisation for the...

journal_title：BJU international

authors： Brunken C,Seitz C,Woo HH

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:To analyse the gene expression level of prostate stem cell antigen (PSCA) in human clear cell renal cell carcinoma (CC-RCC) and its relationship with conventional clinicopathological manifestations, to evaluate its prognostic value for patient outcome, and to determine the effect of PSCA on the progression o...

journal_title：BJU international

authors： Elsamman EM,Fukumori T,Tanimoto S,Nakanishi R,Takahashi M,Toida K,Kanayama HO

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To review systematically all the available evidence on efficacy and safety of cannabinoids for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). PATIENTS AND METHODS:The review was performed according to the Preferred Reporting Items for Systematic Reviews...

journal_title：BJU international

authors： Abo Youssef N,Schneider MP,Mordasini L,Ineichen BV,Bachmann LM,Chartier-Kastler E,Panicker JN,Kessler TM

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To determine whether the density of CD4(+) and CD8(+) T-lymphocytes in a transrectal ultrasonography (TRUS) biopsy of the prostate can be used to predict the progression of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:In total, 100 patients were randomly sel...

journal_title：BJU international

authors： Lamb AD,Qadan M,Roberts S,Timlin H,Vowler SL,Campbell FM,Grigor K,Bartlett JM,McNeill SA

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:• To systematically review and compare the economic burden of open radical cystectomy (ORC) vs robot-assisted laparoscopic radical cystectomy (RALRC) with pelvic lymph node dissection and urinary diversion. PATIENTS AND METHODS:• A Medline search was conducted to identify English language articles regarding ...

journal_title：BJU international

authors： Lee R,Chughtai B,Herman M,Shariat SF,Scherr DS

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To determine the neurophysiological and vascular factors in diabetic impotence, particularly the role of autonomic neuropathy on venous leakage and erectile impotence. PATIENTS AND METHODS:Thirty-four diabetic men with impotence were investigated using various neurophysiological and radiological methods. The...

journal_title：BJU international

authors： Colakoglu Z,Kutluay E,Ertekin C,Altay B,Killi R,Alkis A

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a deep and narrow pelvis on apical positive surgical margins (PSM) at radical prostatectomy (RP), controlling for other clinical and pathological variables and surgical approach, i.e. open retropubic (RRP) vs laparoscopic (LRP), as apical dissection is expected to be more challengin...

journal_title：BJU international

authors： Matikainen MP,von Bodman CJ,Secin FP,Yunis LH,Vora K,Guillonneau B,Laudone V,Eastham JA,Scardino PT,Akin O,Rabbani F

更新日期：2010-09-01 00:00:00