Evaluation of ureteric contraction: a comparison among ring, spiral-cut and longitudinal segments.

Abstract:

OBJECTIVE:To determine the optimal contractile response of isolated ureters to inflammatory mediators and neurotransmitters by evaluating four common methods of ureteric suspension. MATERIALS AND METHODS:Ureters from adult domestic swine were placed immediately in Krebs buffer and cut into 4-5 mm segments. Four methods of suspension were compared: (i) an unopened ring segment suspended horizontally; (ii) a spirally cut segment (lumen cut open at a 45 degrees and suspended end-to-end); (iii) an open longitudinal segment; and (iv) a closed longitudinal segment. All segments were placed in individual water-jacketed tissue baths containing Krebs buffer, the frequency of contraction measured using a force transducer and registered on a polygraph. The sensitivity of all four segments was tested by measuring the tension and frequency in response to increasing frequencies of electric field stimulation, and by a cumulative concentration-response curve to carbachol. RESULTS:Ureteric segments responded with an increased frequency of contraction depending on the intensity of stimulus to both electric field stimulation and carbachol. However, there were no significant differences in spontaneous levels of contraction, sensitivity or maximal response among the methods of suspension in response to electric field stimulation or carbachol. CONCLUSION:These results indicate that all four methods of suspending the ureteric segments produce contractile responses sensitive enough to study the action of various neurotransmitters.

journal_name

BJU Int

journal_title

BJU international

authors

Jerde TJ,Saban R,Nakada SY

doi

10.1046/j.1464-410x.1999.00865.x

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

95-100

issue

1

eissn

1464-4096

issn

1464-410X

journal_volume

83

pub_type

杂志文章
  • Effectiveness of hexaminolevulinate fluorescence cystoscopy for the diagnosis of non-muscle-invasive bladder cancer in daily clinical practice: a Spanish multicentre observational study.

    abstract:OBJECTIVE:To assess the sensitivity and specificity of blue-light cystoscopy (BLC) with hexaminolevulinate as an adjunct to white-light cystoscopy (WLC) vs WLC alone for the detection of non-muscle-invasive bladder cancer (NMIBC), in routine clinical practice in Spain. PATIENTS AND METHOD:An intra-patient comparative,...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/bju.13020

    authors: Palou J,Hernández C,Solsona E,Abascal R,Burgués JP,Rioja C,Cabrera JA,Gutiérrez C,Rodríguez O,Iborra I,Herranz F,Abascal JM,Conde G,Oliva J

    更新日期:2015-07-01 00:00:00

  • Factors associated with satisfaction with prostate cancer care: results from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE).

    abstract:OBJECTIVE:To evaluate the impact of demographic, clinical, treatment and patient-reported parameters on satisfaction with prostate cancer care. Despite the significant worldwide impact of prostate cancer, few data are available specifically addressing satisfaction with treatment-related care. PATIENTS AND METHODS:CaPS...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.11423.x

    authors: Resnick MJ,Guzzo TJ,Cowan JE,Knight SJ,Carroll PR,Penson DF

    更新日期:2013-02-01 00:00:00

  • Impaired cardiopulmonary reserve in an elderly population is related to postoperative morbidity and length of hospital stay after radical cystectomy.

    abstract:OBJECTIVE:To determine the relationship of preoperatively measured cardiorespiratory function, to the development of postoperative complications and length of hospital stay (LOS) in a cohort of patients undergoing radical cystectomy (RC), as RC and conduit formation is curative but is associated with significant postop...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12219

    authors: Prentis JM,Trenell MI,Vasdev N,French R,Dines G,Thorpe A,Snowden CP

    更新日期:2013-07-01 00:00:00

  • Computer-aided ultrasonography (HistoScanning): a novel technology for locating and characterizing prostate cancer.

    abstract:OBJECTIVE:To assess the extent to which prostate HistoScanning (PHS), a new ultrasound-based technology that uses computer-aided analysis to quantify tissue disorganization induced by malignant processes, can identify and characterize foci of prostate cancer compared with step-sectioned radical prostatectomy (RP) speci...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2007.07232.x

    authors: Braeckman J,Autier P,Garbar C,Marichal MP,Soviany C,Nir R,Nir D,Michielsen D,Bleiberg H,Egevad L,Emberton M

    更新日期:2008-02-01 00:00:00

  • Long-term results of a combination of paclitaxel, cisplatin and gemcitabine for salvage therapy in male germ-cell tumours.

    abstract:OBJECTIVE:To retrospectively review the long-term activity, efficacy and toxicity of the combination of paclitaxel, cisplatin and gemcitabine (TPG) as third- or further-line chemotherapy in patients with germ-cell tumours (GCTs) who are not cured after at least two courses of standard-dose chemotherapy, high-dose chemo...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2009.08453.x

    authors: Nicolai N,Necchi A,Gianni L,Piva L,Biasoni D,Torelli T,Stagni S,Milani A,Pizzocaro G,Salvioni R

    更新日期:2009-08-01 00:00:00

  • Urinary, bowel and sexual health in older men from Northern Ireland.

    abstract:OBJECTIVES:To provide data on the prevalence of urinary, bowel and sexual dysfunction in Northern Ireland (NI), to act as a baseline for studies of prostate cancer outcomes and to aid service provision within the general population. SUBJECTS AND METHODS:A cross-sectional postal survey of 10 000 men aged ≥40 years in N...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.14182

    authors: Donnelly DW,Donnelly C,Kearney T,Weller D,Sharp L,Downing A,Wilding S,Wright P,Kind P,Catto JWF,Cross WR,Mason MD,McCaughan E,Wagland R,Watson E,Mottram R,Allen M,Butcher H,Hounsome L,Selby P,Huws D,Brewster DH

    更新日期:2018-11-01 00:00:00

  • Biochemical composition of urolithiasis from stone dust - a matched-pair analysis.

    abstract:OBJECTIVE:To determine if the biochemical composition of a renal calculus can be measured from 'dust' obtained during laser fragmentation. PATIENTS AND METHODS:This pilot study was set in a tertiary referral hospital between 2011 and 2013. Stone dust was aspirated through the ureteroscope during lasering and a stone f...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13448

    authors: Ray ER,Rumsby G,Smith RD

    更新日期:2016-10-01 00:00:00

  • The conservative management of corynebacterium group D2 encrusted pyelitis.

    abstract:OBJECTIVE:To evaluate the conservative management of encrusted pyelitis (EP), an infectious disease caused by urea-splitting micro-organisms (Corynebacterium group D2 being the most common), and characterized by stone encrustation of the collecting system. PATIENTS AND METHODS:Four patients (aged 17-62 years) with EP ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.1999.00156.x

    authors: Meria P,Desgrippes A,Fournier R,Arfi C,Antoine C,Martinat L,Teillac P,Le Duc A

    更新日期:1999-08-01 00:00:00

  • Laparoscopic renal biopsy: a 9-year experience.

    abstract:OBJECTIVES:To present our experience and outcome of consecutive laparoscopic renal biopsy over a 9-year period, as renal biopsy remains an important diagnostic procedure for evaluating proteinuria, haematuria and renal failure, but when percutaneous biopsy is contraindicated, a laparoscopic biopsy is an attractive opti...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2003.04243.x

    authors: Shetye KR,Kavoussi LR,Ramakumar S,Fugita OE,Jarrett TW

    更新日期:2003-06-01 00:00:00

  • Repeating the measurement of prostate-specific antigen in symptomatic men can avoid unnecessary prostatic biopsy.

    abstract:OBJECTIVES:To report the 2-year clinical and biochemical follow-up of symptomatic men who had a high prostate-specific-antigen (PSA) level, for whom our policy has been to avoid biopsy in those with a normal repeat PSA, as minimizing negative prostate biopsies is an important goal in managing men with a high PSA, where...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410x.2003.04533.x

    authors: Singh R,Cahill D,Popert R,O'Brien TS

    更新日期:2003-12-01 00:00:00

  • In vivo evaluation of the potency and bladder-vascular selectivity of the ATP-sensitive potassium channel openers (-)-cromakalim, ZD6169 and WAY-133537 in rats.

    abstract:OBJECTIVE:To compare in vivo the potency and bladder-vascular selectivity of ATP-sensitive potassium channel openers (KCOs) (-)-cromakalim, WAY-133537 and ZD6169 and a muscarinic antagonist, tolterodine in rats. MATERIALS AND METHODS:Bladder and arterial pressures were monitored simultaneously, before and after increa...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2003.03069.x

    authors: Fabiyi AC,Gopalakrishnan M,Lynch JJ 3rd,Brioni JD,Coghlan MJ,Brune ME

    更新日期:2003-02-01 00:00:00

  • Improving the prognosis of patients after radical cystectomy. Part I: the role of lymph node dissection.

    abstract::The first two reviews are from the same unit in Germany and describe the well-known but still much discussed ways of improving the prognosis of patients undergoing cystectomy for bladder cancer. The authors review the roles of lymph node dissection and perioperative chemotherapy, and draw conclusions which will be of ...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2007.07114.x

    authors: Suttmann H,Kamradt J,Lehmann J,Stöckle M

    更新日期:2007-12-01 00:00:00

  • An in vivo evaluation of the therapeutic potential of sympatholytic agents on premature ejaculation.

    abstract:OBJECTIVE:To evaluate the therapeutic potential of sympatholytic agents on premature ejaculation in an animal model, using monitoring of rat seminal vesicle pressure change in response to electrical stimulation of the lesser splanchnic nerve. MATERIALS AND METHODS:Male Wistar rats (aged 12-14 weeks) were injected intr...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.1999.00173.x

    authors: Hsieh JT,Liu SP,Hsieh CH,Cheng JT

    更新日期:1999-09-01 00:00:00

  • Changing USA national trends for adrenalectomy: the influence of surgeon and technique.

    abstract:OBJECTIVE:To explain differences over time between operative approach and surgeon type for adrenal surgery in the USA. PATIENTS AND METHODS:A retrospective cohort analysis was performed on all patients undergoing adrenalectomy between 2002 and 2011 using the Nationwide Inpatient Sample. Patients undergoing concurrent ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12747

    authors: Monn MF,Calaway AC,Mellon MJ,Bahler CD,Sundaram CP,Boris RS

    更新日期:2015-02-01 00:00:00

  • Bladder calculi in children who perform clean intermittent catheterization.

    abstract:OBJECTIVE:To examine the role of clean intermittent catheterization (CIC) as a possible predisposing risk factor for bladder calculi, assessing risk factors in patients with and without bladder augmentation, and to evaluate management options for bladder calculi in these patients. PATIENTS AND METHODS:The records of 4...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2000.00625.x

    authors: Barroso U,Jednak R,Fleming P,Barthold JS,González R

    更新日期:2000-05-01 00:00:00

  • Detection of urinary leakage after radical retropubic prostatectomy by contrast enhanced ultrasound - do we still need conventional retrograde cystography?

    abstract:INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09497.x

    authors: Schoeppler GM,Buchner A,Zaak D,Khoder W,Staehler M,Stief CG,Reiser MF,Clevert DA

    更新日期:2010-12-01 00:00:00

  • Metoidioplasty: a variant of phalloplasty in female transsexuals.

    abstract:OBJECTIVE:To describe metoidioplasty, a technique for creating a neophallus from an enlarged clitoris in female transsexuals, without needing the complex, multi-staged surgical construction of a large phallus, as this reconstruction is one of the most difficult in female transsexuals. PATIENTS AND METHODS:From Septemb...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410x.2003.04524.x

    authors: Perovic SV,Djordjevic ML

    更新日期:2003-12-01 00:00:00

  • Lower urinary tract symptoms, benign prostatic obstruction and the overactive bladder.

    abstract::Lower urinary tract symptoms (LUTS), benign prostatic obstruction (BPO), and the overactive bladder have increasing prevalence with age in both men and women (with the obvious exception). The question is, are they interrelated or independently related to age? The specific issue is whether BPO causes the overactive bla...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410x.2000.tb16953.x

    authors: Thomas AW,Abrams P

    更新日期:2000-05-01 00:00:00

  • Bacillus Calmette-Guérin cell-wall skeleton enhances the killing activity of cytotoxic lymphocyte-activated human dendritic cells transduced with the prostate-specific antigen gene.

    abstract:UNLABELLED:To determine whether dendritic cells (DC) transduced with the prostate-specific antigen (PSA) gene can induce PSA-specific cytotoxic lymphocytes (CTL) against prostate cancer cells, and whether bacillus Calmette-Guérin (BCG) cell-wall skeleton (CWS) can enhance the maturation of DC-PSA and the killing activi...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410x.2009.08703.x

    authors: Fujii R,Iwahashi M,Kikkawa K,Inagaki T,Kohjimoto Y,Ojima T,Mori T,Kuramoto T,Nishizawa S,Azuma I,Yamaue H,Shinka T,Hara I

    更新日期:2009-12-01 00:00:00

  • The obesity paradox: defining the impact of body mass index and diabetes mellitus for patients with non-muscle-invasive bladder cancer treated with bacillus Calmette-Guérin.

    abstract:OBJECTIVES:To evaluate if the obesity paradox, wherein obesity portends worse overall prognosis for a disease but improved outcomes for patients receiving immunotherapy, exists for patients receiving bacillus Calmette-Guérin (BCG) in a contemporary cohort. PATIENTS AND METHODS:We performed an Institutional Review Boar...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.15296

    authors: Brooks NA,Kokorovic A,Xiao L,Matulay JT,Li R,Ranasinghe WKB,Nagaraju S,Shen Y,Gao J,Navai N,Dinney CPN,Grossman HB,Kamat AM

    更新日期:2020-11-14 00:00:00

  • Preliminary evidence that the allogeneic response might trigger antitumour immunity in patients with advanced prostate cancer.

    abstract:OBJECTIVE:To explore the possibility that allogeneic responses might, by chance, encompass cross-reactive T cell clones specific for neo-antigenic tumour determinants, and thereby activate antitumour immunity; such cross-reactions are well documented for antiviral immunity, and genetic instability in developing cancers...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1464-410X.2006.06421.x

    authors: Muir G,Rajbabu K,Callen C,Fabre JW

    更新日期:2006-11-01 00:00:00

  • Renal autotransplantation for managing a short upper ureter or after ex vivo complex renovascular reconstruction.

    abstract:OBJECTIVE:To report our contemporary experience with renal autotransplantation (AT), an established treatment for managing patients with a shortened ureter or renovascular disease, as despite its historical importance, AT remains an underused technique by urologists. PATIENTS AND METHODS:All patients undergoing AT bet...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05729.x

    authors: Webster JC,Lemoine J,Seigne J,Lockhart J,Bowers V

    更新日期:2005-10-01 00:00:00

  • Proportion of tadalafil-treated patients with clinically meaningful improvement in lower urinary tract symptoms associated with benign prostatic hyperplasia – integrated data from 1,499 study participants.

    abstract:OBJECTIVES:To evaluate the proportion of patients achieving clinically meaningful improvement of lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH-LUTS) with tadalafil using two definitions of response. PATIENTS AND METHODS:Post hoc integrated analysis of four placebo-controlled studies in m...

    journal_title:BJU international

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/bju.12926

    authors: Nickel JC,Brock GB,Herschorn S,Dickson R,Henneges C,Viktrup L

    更新日期:2015-05-01 00:00:00

  • Abnormal glycosylation of Tamm-Horsfall protein in patients with interstitial cystitis.

    abstract:OBJECTIVE:To confirm abnormal glycosylation of Tamm-Horsfall protein (THP) in patients with interstitial cystitis (IC). PATIENTS, SUBJECTS AND METHODS:The sialic acid content of THP, a critical component of its biological activity, is reduced in patients with IC. N-glycan shows reduced levels of high molecular weight ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2008.08163.x

    authors: Argade SP,Vanichsarn C,Chenoweth M,Parsons CL

    更新日期:2009-04-01 00:00:00

  • What is the current status of revalidation in urology?

    abstract::The aim of revalidation (or maintenance of certification) is to reassure patients, the general public, employers and other healthcare professionals that an individual is fit to practice. It may lead to a reduction in near misses or adverse events. The process of revalidation entails a commitment to the provision of li...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2011.10375.x

    authors: Ahmed K,Zakri R,Rowland S,Joyce A,Challacombe B,Dasgupta P,Khan MS

    更新日期:2011-10-01 00:00:00

  • Review article: Mid-urethral synthetic slings for female stress urinary incontinence.

    abstract::• Mid-urethral synthetic slings (MUSS) have grown in acceptance and popularity to gain a foremost position in stress urinary incontinence (SUI) surgery. • There are numerous studies that provide a large amount of Level 1 and 2 evidence that support the concept of a sling placed at the level of the mid-urethra. • Long-...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2010.09544.x

    authors: Fong ED,Nitti VW

    更新日期:2010-09-01 00:00:00

  • Implementing newer agents for the management of castrate-resistant prostate cancer: what is known and what is needed?

    abstract::Men receiving androgen-deprivation therapy will in time develop metastatic castrate-resistant prostate cancer (mCRPC). Whilst effective treatment options for mCRPC have traditionally been limited, new agents are becoming available. Since 2010, the number and class of agents available to treat mCRPC has increased drama...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/bju.12736

    authors: Mottet N,Clarke N,De Santis M,Zattoni F,Morote J,Joniau S

    更新日期:2015-03-01 00:00:00

  • Testosterone and erectile function recovery after radiotherapy and long-term androgen deprivation with luteinizing hormone-releasing hormone agonists.

    abstract:OBJECTIVE:To study the recovery of testosterone levels and erectile function in men who received radiotherapy plus long-term adjuvant androgen deprivation (LTAD) with luteinizing hormone-releasing hormone (LHRH) agonists. PATIENTS AND METHODS:From April 2000 to July 2001, men who had completed prostate radiotherapy wi...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2006.06066.x

    authors: Wilke DR,Parker C,Andonowski A,Tsuji D,Catton C,Gospodarowicz M,Warde P

    更新日期:2006-05-01 00:00:00

  • Changing practice in anterior urethroplasty.

    abstract:OBJECTIVE:To describe our experience of penile urethral repair and reconstruction, cataloguing the change in practice from one-stage flap to two-stage free graft procedures for anterior urethroplasty. PATIENTS AND METHODS:Between January 1992 and December 1996, 79 patients underwent anterior urethroplasty. Of the 45 o...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.1999.00010.x

    authors: Greenwell TJ,Venn SN,Mundy AR

    更新日期:1999-04-01 00:00:00

  • Elective segmental ureterectomy for transitional cell carcinoma of the ureter: long-term follow-up in a series of 73 patients.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? Upper Urinary Tract (UUT) Transitional Cell Carcinoma (TCC) is an uncommon disease and represents approximately 5% of all urothelial carcinomas. We report our series on 73 patients treated with Kidney Sparing Surgery for UUT TCC. Good results have bee...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1464-410X.2012.11554.x

    authors: Simonato A,Varca V,Gregori A,Benelli A,Ennas M,Lissiani A,Gacci M,De Stefani S,Rosso M,Benvenuto S,Siena G,Belgrano E,Gaboardi F,Carini M,Bianchi G,Carmignani G

    更新日期:2012-12-01 00:00:00