Changing practice in anterior urethroplasty.

Abstract:

OBJECTIVE:To describe our experience of penile urethral repair and reconstruction, cataloguing the change in practice from one-stage flap to two-stage free graft procedures for anterior urethroplasty. PATIENTS AND METHODS:Between January 1992 and December 1996, 79 patients underwent anterior urethroplasty. Of the 45 one-stage bulbar patch urethroplasties, 37 (76%) used buccal mucosal free grafts rather than flaps. Of the 34 penile urethroplasties, 26 (82%) (including all of the circumferential reconstructions) were two-stage procedures. RESULTS:Buccal mucosal free grafts were at least as good as local skin flaps for patch urethroplasty and two-stage repairs gave much better results than one-stage repairs for total circumferential reconstruction of the penile urethra. CONCLUSIONS:For a patch urethroplasty of an uncomplicated stricture in the bulbar urethra, buccal mucosal free grafts are now the material of choice. For a patch urethroplasty of an uncomplicated stricture in the penile urethra the Orandi procedure remains the 'gold standard'. For a circumferential repair of the urethra, particularly the penile urethra, a two-stage repair using a free graft gives better results than a one-stage repair using a flap.

journal_name

BJU Int

journal_title

BJU international

authors

Greenwell TJ,Venn SN,Mundy AR

doi

10.1046/j.1464-410x.1999.00010.x

keywords:

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

631-5

issue

6

eissn

1464-4096

issn

1464-410X

journal_volume

83

pub_type

杂志文章
  • Prediction of stone disease by discriminant analysis and artificial neural networks in genetic polymorphisms: a new method.

    abstract:OBJECTIVE:To use information from genetic polymorphisms and from patients (drinking/exercise habits) to identify their association with stone disease, the main analytical and predictive tools being discriminant analysis (DA) and artificial neural networks (ANNs). PATIENTS, SUBJECTS AND METHODS:Urinary stone disease is...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1464-410x.2003.03067.x

    authors: Chiang D,Chiang HC,Chen WC,Tsai FJ

    更新日期:2003-05-01 00:00:00

  • Cost-effectiveness analysis of degarelix for advanced hormone-dependent prostate cancer.

    abstract:OBJECTIVE:To evaluate the cost-effectiveness of degarelix vs luteinizing hormone-releasing hormone analogue (triptorelin) plus short-term antiandrogen treatment for advanced prostate cancer. METHODS:We developed a decision analytic model based on a clinical trial and literature review. The two interventions evaluated ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2011.10434.x

    authors: Lu L,Peters J,Roome C,Stein K

    更新日期:2012-04-01 00:00:00

  • Changes in patient characteristics and outcomes for radical cystectomy in England.

    abstract:OBJECTIVES:To describe temporal changes in patient characteristics and outcomes for radical cystectomy (RC) in England between 1995 and 2002, using routinely collected administrative data. PATIENTS AND METHODS:Data were extracted from the Hospital Episode Statistics database of the Department of Health in England, des...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05329.x

    authors: Nuttall MC,van der Meulen J,McIntosh G,Gillatt D,Emberton M

    更新日期:2005-03-01 00:00:00

  • Effect of firing rate on the performance of shock wave lithotriptors.

    abstract:OBJECTIVE:To determine the mechanism that underlies the effect of shock wave (SW) rate on the performance of clinical lithotripters. MATERIALS AND METHODS:The effect of firing rate on the pressure characteristics of SWs was assessed using a fibre-optic probe hydrophone (FOPH 500, RP Acoustics, Leutenbach, Germany). Sh...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2008.07896.x

    authors: Pishchalnikov YA,McAteer JA,Williams JC Jr

    更新日期:2008-12-01 00:00:00

  • Pharmacological preconditioning of ATP-sensitive potassium channel openers on acute urinary retention-induced bladder dysfunction in the rat.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? Acute urinary retention (AUR) and catheterization for AUR (AURC) or drainage of the urine is a well established cause of bladder dysfunction. Previously, we reported that the induction of AURC significantly reduced contractile responses to both carbac...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.10965.x

    authors: Ohmasa F,Saito M,Oiwa H,Tsounapi P,Shomori K,Kitatani K,Dimitriadis F,Kinoshita Y,Satoh K

    更新日期:2012-09-01 00:00:00

  • Evaluating the role of the FSH receptor gene Thr307-Ala and Asn680-Ser polymorphisms in male infertility and their association with semen quality and reproductive hormones.

    abstract:OBJECTIVE:To determine whether Thr(307)-Asn(680) and Ala(307)-Ser(680) polymorphisms of the follicle-stimulating hormone receptor (FSH-R) gene are associated with male infertility, semen quality, and reproductive hormones. PATIENTS AND METHODS:The FSH-R polymorphisms at codons 680 and 307 were analysed by restriction-...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09890.x

    authors: Safarinejad MR,Shafiei N,Safarinejad S

    更新日期:2011-07-01 00:00:00

  • The optimal form of urinary drainage after acute retention of urine.

    abstract:OBJECTIVE:To assess the outcome of different forms of urinary drainage, particularly for urinary tract infection (UTI), operative findings and patient preference, in patients treated for acute urinary retention (AUR). PATIENTS AND METHODS:A feasibility trial was conducted of men presenting with AUR; after a short peri...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2001.02253.x

    authors: Patel MI,Watts W,Grant A

    更新日期:2001-07-01 00:00:00

  • New blood-based biomarkers for the diagnosis, staging and prognosis of prostate cancer.

    abstract::The introduction of prostate-specific antigen (PSA) has revolutionized the detection and management of patients with prostate cancer. Despite this there has always been a concern among clinicians about the usefulness of total PSA levels as a marker for prostate cancer. We discuss the use of calculated variables and mo...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2007.07283.x

    authors: Shariat SF,Karam JA,Margulis V,Karakiewicz PI

    更新日期:2008-03-01 00:00:00

  • Sensory evoked potentials of the bladder and urethra in middle-aged women: the effect of age.

    abstract:OBJECTIVES:To investigate feasibility, reproducibility and age dependency of sensory evoked cortical potentials (SEPs) after electrical stimulation of different locations in the lower urinary tract (LUT) in a cohort of middle-aged healthy women. SUBJECTS AND METHODS:In a group of 10 healthy middle-aged women [mean (sd...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13066

    authors: Gregorini F,Knüpfer SC,Liechti MD,Schubert M,Curt A,Kessler TM,Mehnert U

    更新日期:2015-04-01 00:00:00

  • Increasing age is not associated with toxicity leading to discontinuation of treatment in patients with urothelial non-muscle-invasive bladder cancer randomised to receive 3 years of maintenance bacille Calmette-Guérin: results from European Organisation

    abstract:OBJECTIVE:To determine the relationship of age to side-effects leading to discontinuation of treatment in patients with stage Ta-T1 non-muscle-invasive bladder cancer (NMIBC) treated with maintenance bacille Calmette-Guérin (BCG). PATIENTS AND METHODS:We evaluated toxicity for 487 eligible patients with intermediate- ...

    journal_title:BJU international

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/bju.13474

    authors: Oddens JR,Sylvester RJ,Brausi MA,Kirkels WJ,van de Beek C,van Andel G,de Reijke TM,Prescott S,Alfred Witjes J,Oosterlinck W

    更新日期:2016-09-01 00:00:00

  • Comparison of oncological outcomes of transperitoneal and retroperitoneal laparoscopic radical nephrectomy for the management of clear-cell renal cell carcinoma: a multi-institutional study.

    abstract:OBJECTIVE:• To investigate the oncological efficacy of retroperitoneal laparoscopic radical nephrectomy (RLRN) compared with transperitoneal laparoscopic radical nephrectomy (TLRN) for the management of clear-cell renal cell carcinoma (RCC). PATIENTS AND METHODS:• With emphasis on survival and disease recurrence, a re...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1464-410X.2010.09636.x

    authors: Ha US,Hwang TK,Kim YJ,Oh TH,Jeon YS,Lee W,Lim JS,Lee TY,Choi Y,Park SK,Byun SS

    更新日期:2011-05-01 00:00:00

  • Chemotherapy for advanced adrenal cancer: improvement from a molecular approach?

    abstract::Advanced adrenal carcinoma remains a significant therapeutic challenge, with conventional approaches to systemic therapy having failed to achieve sustained objective remissions or major survival benefit in most instances. Several systemic therapies, including mitotane, suramin and gossypol, as well as cytotoxic agents...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2011.10464.x

    authors: Costa R,Wesolowski R,Raghavan D

    更新日期:2011-11-01 00:00:00

  • Cancer ablation with regional templates applied to prostatectomy specimens from men who were eligible for focal therapy.

    abstract:OBJECTIVE:To assess the totality of prostate cancer eradication in radical prostatectomy (RP) specimens from men with a unilaterally positive prostate biopsy, and who would currently qualify for subtotal prostate ablation with controlled thermal energy such as cryoablation or high-intensity focused ultrasound. MATERIA...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2009.08359.x

    authors: Ward JF,Nakanishi H,Pisters L,Babaian RJ,Troncoso P

    更新日期:2009-08-01 00:00:00

  • The prognostic significance of advanced age in patients with bladder cancer treated with radical cystectomy.

    abstract:OBJECTIVE:To evaluate the association of patient age with pathological and long-term oncological outcomes after radical cystectomy (RC) for bladder carcinoma, as this disease, like many others, increases in incidence with age. PATIENTS AND METHODS:We retrospectively reviewed 241 consecutive patients with invasive blad...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2008.08033.x

    authors: Resorlu B,Beduk Y,Baltaci S,Ergun G,Talas H

    更新日期:2009-02-01 00:00:00

  • The 'top 10' urological procedures: a study of hospital episodes statistics 1998-99.

    abstract:OBJECTIVE:To summarize the urological procedures recorded in Hospital Episodes Statistics (HES, 1998-99) and to examine the accuracy of coding and HES. MATERIALS AND METHODS:Data on the 10 commonest urological procedures from the Department of Health website (www.doh.gov.uk/hes) were extracted, summarized and presente...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2002.02833.x

    authors: Lee F,Patel HR,Emberton M

    更新日期:2002-07-01 00:00:00

  • CD4+ and CD8+ T-lymphocyte scores cannot reliably predict progression in patients with benign prostatic hyperplasia.

    abstract:OBJECTIVE:To determine whether the density of CD4(+) and CD8(+) T-lymphocytes in a transrectal ultrasonography (TRUS) biopsy of the prostate can be used to predict the progression of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:In total, 100 patients were randomly sel...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09787.x

    authors: Lamb AD,Qadan M,Roberts S,Timlin H,Vowler SL,Campbell FM,Grigor K,Bartlett JM,McNeill SA

    更新日期:2011-07-01 00:00:00

  • Symptomatic overlap in overactive bladder and interstitial cystitis/bladder pain syndrome: development of a new algorithm.

    abstract:OBJECTIVES:To address challenges in the diagnosis and classification of storage lower urinary tract symptoms (LUTS), we sought to define the fundamental features of overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/BPS), two conditions with considerable symptomatic overlap. Through retrospect...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.14568

    authors: Ackerman AL,Lai HH,Parameshwar PS,Eilber KS,Anger JT

    更新日期:2019-04-01 00:00:00

  • Use of oxidized cellulose for corporal body grafting and suture-less correction of severe penile chordee: an experimental study in rabbits.

    abstract:OBJECTIVE:To evaluate the efficacy of oxidized cellulose, Surgicel(TM) (Johnson & Johnson Medical, New Brunswick, NJ, USA) for patching defects in the tunica albuginea in a rabbit model, with a future application to correct chordee. MATERIALS AND METHODS:The study comprised nine New Zealand white male rabbits; a recta...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2006.06684.x

    authors: El-Assmy A,Eassa W,El-Hamid MA,Nour EM,Hafez AT

    更新日期:2007-05-01 00:00:00

  • Surveillance for bladder cancer: the management of 4.8 million people. South-west Urologists.

    abstract:OBJECTIVE:To document the workload of bladder cancer surveillance on the British urologist. Methods Thirty-one consultant urologists serving a population of 4.8 million were sent postal questionnaires eliciting their views on the management of superficial bladder cancer. The number, type and outcome of cystoscopies per...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2000.00467.x

    authors: Wright MP,Jones DJ

    更新日期:2000-03-01 00:00:00

  • Establishing the role of cytokine therapy in advanced renal cell carcinoma.

    abstract::Tribute to Professor Pieter De Mulder, from Martin Gore. Pieter and I were often pitted against each other in debates at international meetings on the role of cytokine therapy. The truth is that there was little disagreement between us, but we both thought such set pieces were a good way to highlight the issues surrou...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2008.07435.x

    authors: Gore ME,De Mulder P

    更新日期:2008-05-01 00:00:00

  • Transient receptor potential vanilloid 1 mediates nerve growth factor-induced bladder hyperactivity and noxious input.

    abstract:OBJECTIVES:To explore the role of transient receptor potential vanilloid 1 (TRPV1) in the excitatory effects of chronic administration of nerve growth factor (NGF) on bladder-generated sensory input and reflex activity. To explore new therapeutic targets for bladder dysfunction. MATERIALS AND METHODS:Wild-type (WT) an...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.11187.x

    authors: Frias B,Charrua A,Avelino A,Michel MC,Cruz F,Cruz CD

    更新日期:2012-10-01 00:00:00

  • Am I normal? A systematic review and construction of nomograms for flaccid and erect penis length and circumference in up to 15,521 men.

    abstract:OBJECTIVE:To systematically review and create nomograms of flaccid and erect penile size measurements. METHODS:Study key eligibility criteria: measurement of penis size by a health professional using a standard procedure; a minimum of 50 participants per sample. EXCLUSION CRITERIA:samples with a congenital or acquire...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/bju.13010

    authors: Veale D,Miles S,Bramley S,Muir G,Hodsoll J

    更新日期:2015-06-01 00:00:00

  • Experience with a bone anchor sling for treating female stress urinary incontinence: outcome at 30 months.

    abstract:OBJECTIVES:To evaluate the clinical and video-urodynamic outcome in women with by stress urinary incontinence (SUI) treated with a bone-anchored pubovaginal sling. PATIENTS AND METHODS:The study included 70 women with SUI (as evaluated by a clinical examination, a voiding questionnaire, a short pad-test and video-urod...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410x.2003.04749.x

    authors: Carbone A,Palleschi G,Ciavarella S,Morello P,Tomiselli G,Parascani R,Tubaro A

    更新日期:2004-04-01 00:00:00

  • Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro.

    abstract:OBJECTIVE:To investigate the mechanisms of neurokinin A- and substance P-induced contractions of rat urinary bladder smooth muscle, and to compare them with those of the muscarinic agonist carbachol. MATERIALS AND METHODS:Rat urinary bladder strips were suspended under 1 g of tension in a physiological buffer at 37 de...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2004.05017.x

    authors: Quinn T,Collins C,Baird AW

    更新日期:2004-09-01 00:00:00

  • Open radical prostatectomy in the elderly: a case for concern?

    abstract:UNLABELLED:Study Type--Therapy (case series). Level of Evidence 4. What's known on the subject? And what does the study add? Adverse outcomes after radical prostatectomy are more often recorded in the elderly. In the USA, elderly patients undergoing radical prostatectomy are treated at institutions where suboptimal out...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2011.10554.x

    authors: Trinh QD,Schmitges J,Sun M,Shariat SF,Sukumar S,Tian Z,Bianchi M,Sammon J,Perrotte P,Rogers CG,Graefen M,Peabody JO,Menon M,Karakiewicz PI

    更新日期:2012-05-01 00:00:00

  • One-sided anterior urethroplasty: a new dorsal onlay graft technique.

    abstract:OBJECTIVE:To investigate the feasibility, tolerability, safety and efficacy of using a new surgical technique for the repair of anterior urethral strictures to preserve vascular supply to the urethra and its entire muscular and neurogenic support. PATIENTS AND METHODS:In all, 24 patients (mean age 46 years) underwent ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2009.08590.x

    authors: Kulkarni S,Barbagli G,Sansalone S,Lazzeri M

    更新日期:2009-10-01 00:00:00

  • Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammation.

    abstract:OBJECTIVE:• To determine (i) the presence of fatty acid amide hydrolase (FAAH) in the urinary bladder; (ii) whether or not endogenous fatty acid ethanolamides are synthesized by the bladder; (iii) the effects of FAAH inhibition on referred hyperalgesia associated with acute bladder inflammation in rats. MATERIALS AND ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09583.x

    authors: Merriam FV,Wang ZY,Hillard CJ,Stuhr KL,Bjorling DE

    更新日期:2011-10-01 00:00:00

  • Reduced estimated glomerular filtration rate (eGFR

    abstract:OBJECTIVE:To evaluate if moderate chronic kidney disease [CKD; estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2 ] is associated with high rates of non-muscle-invasive bladder cancer (NMIBC) recurrence or progression. PATIENTS AND METHODS:A multi-institutional database identified patients with serum creat...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13904

    authors: Blute ML Jr,Kucherov V,Rushmer TJ,Damodaran S,Shi F,Abel EJ,Jarrard DF,Richards KA,Messing EM,Downs TM

    更新日期:2017-09-01 00:00:00

  • Clinicopathological outcomes after radical cystectomy for clinical T2 urothelial carcinoma: further evidence to support the use of neoadjuvant chemotherapy.

    abstract:OBJECTIVE:To evaluate the clinicopathological outcomes for patients with clinical T2 (cT2) urothelial carcinoma treated with radical cystectomy (RC) without neoadjuvant chemotherapy (NC). PATIENTS AND METHODS:We identified 212 patients with cT2 tumours who underwent RC at our institution without NC. Pathological asses...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09442.x

    authors: Canter D,Long C,Kutikov A,Plimack E,Saad I,Oblaczynski M,Zhu F,Viterbo R,Chen DY,Uzzo RG,Greenberg RE,Boorjian SA

    更新日期:2011-01-01 00:00:00

  • Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis.

    abstract:OBJECTIVE:To examine the chemopreventive effects of a selective cyclooxygenase (COX)-2 inhibitor, meloxicam, and a selective epidermal growth factor (EGF)-receptor tyrosine kinase inhibitor, gefitinib (as a single agent) on a carcinogen-induced rodent bladder carcinogenesis model. MATERIALS AND METHODS:The study compr...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2006.06053.x

    authors: Hattori K,Iida K,Joraku A,Tsukamoto S,Akaza H,Oyasu R

    更新日期:2006-03-01 00:00:00