Abstract:
OBJECTIVES:To provide data on the prevalence of urinary, bowel and sexual dysfunction in Northern Ireland (NI), to act as a baseline for studies of prostate cancer outcomes and to aid service provision within the general population. SUBJECTS AND METHODS:A cross-sectional postal survey of 10 000 men aged ≥40 years in NI was conducted and age-matched to the distribution of men living with prostate cancer. The EuroQoL five Dimensions five Levels (EQ-5D-5L) and 26-item Expanded Prostate Cancer Composite (EPIC-26) instruments were used to enable comparisons with prostate cancer outcome studies. Whilst representative of the prostate cancer survivor population, the age-distribution of the sample differs from the general population, thus data were generalised to the NI population by excluding those aged 40-59 years and applying survey weights. Results are presented as proportions reporting problems along with mean composite scores, with differences by respondent characteristics assessed using chi-squared tests, analysis of variance, and multivariable log-linear regression. RESULTS:Amongst men aged ≥60 years, 32.8% reported sexual dysfunction, 9.3% urinary dysfunction, and 6.5% bowel dysfunction. In all, 38.1% reported at least one problem and 2.1% all three. Worse outcome was associated with increasing number of long-term conditions, low physical activity, and higher body mass index (BMI). Urinary incontinence, urinary irritation/obstruction, and sexual dysfunction increased with age; whilst urinary incontinence, bowel, and sexual dysfunction were more common among the unemployed. CONCLUSION:These data provide an insight into sensitive issues seldom reported by elderly men, which result in poor general health, but could be addressed given adequate service provision. The relationship between these problems, raised BMI and low physical activity offers the prospect of additional health gain by addressing public health issues such as obesity. The results provide essential contemporary population data against which outcomes for those living with prostate cancer can be compared. They will facilitate greater understanding of the true impact of specific treatments such as surgical interventions, pelvic radiation or androgen-deprivation therapy.
journal_name
BJU Intjournal_title
BJU internationalauthors
Donnelly DW,Donnelly C,Kearney T,Weller D,Sharp L,Downing A,Wilding S,Wright P,Kind P,Catto JWF,Cross WR,Mason MD,McCaughan E,Wagland R,Watson E,Mottram R,Allen M,Butcher H,Hounsome L,Selby P,Huws D,Brewster DHdoi
10.1111/bju.14182subject
Has Abstractpub_date
2018-11-01 00:00:00pages
845-857issue
5eissn
1464-4096issn
1464-410Xjournal_volume
122pub_type
杂志文章abstract:OBJECTIVE:To assess the totality of prostate cancer eradication in radical prostatectomy (RP) specimens from men with a unilaterally positive prostate biopsy, and who would currently qualify for subtotal prostate ablation with controlled thermal energy such as cryoablation or high-intensity focused ultrasound. MATERIA...
journal_title:BJU international
pub_type: 杂志文章
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journal_title:BJU international
pub_type: 杂志文章
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07896.x
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12170
更新日期:2013-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1464-410x.2003.04462.x
更新日期:2003-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08622.x
更新日期:2009-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2007.07283.x
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abstract:OBJECTIVE:To define changes in the clinical pathway for open radical retropubic prostatectomy (RRP) and to determine their impact on patient care under the indirect influence of minimally invasive prostatectomy after implementing robotically assisted laparoscopic prostatectomy (RALP) at our institution and modifying th...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05993.x
更新日期:2006-03-01 00:00:00
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pub_type: 杂志文章
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02833.x
更新日期:2002-07-01 00:00:00
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pub_type: 杂志文章,meta分析
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journal_title:BJU international
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08288.x
更新日期:2009-07-01 00:00:00
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doi:10.1111/j.1464-410X.2009.09184.x
更新日期:2010-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.09144.x
更新日期:2010-09-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07232.x
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,meta分析
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更新日期:2005-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00597.x
更新日期:2000-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06508.x
更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2009-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02357.x
更新日期:2001-10-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07338.x
更新日期:2008-03-01 00:00:00