Expression and localization of basic fibroblast growth factor in diabetic rat prostate.

abstract：OBJECTIVE:To investigate the mechanisms of neurokinin A- and substance P-induced contractions of rat urinary bladder smooth muscle, and to compare them with those of the muscarinic agonist carbachol. MATERIALS AND METHODS:Rat urinary bladder strips were suspended under 1 g of tension in a physiological buffer at 37 de...

journal_title：BJU international

authors： Quinn T,Collins C,Baird AW

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To present the results of the first clinical study of a synchronous twin-pulse technique for extracorporeal shock-wave lithotripsy (ESWL), which is effective for in vitro stone fragmentation and safe when assessed in vivo on animal tissue. PATIENTS AND METHODS:Fifty patients with urinary stones (35 men and 1...

journal_title：BJU international

authors： Sheir KZ,El-Diasty TA,Ismail AM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To assess the factors that influence the onset of androgen independence (AI, which heralds a dismal outcome) in patients with metastatic prostate carcinoma. PATIENTS AND METHODS:The records of 361 consecutive patients with prostate carcinoma diagnosed and treated in the authors' institution from 1 January 19...

journal_title：BJU international

authors： Sim HG,Lau WK,Cheng CW

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the relevance of ureterocele ectopia and associated reflux on the outcome of duplex system ureteroceles (DSU) after neonatal transurethral incision (TUI). PATIENTS AND METHODS:The study included 41 neonates with a diagnosis of DSU; the ureterocele was ectopic in 24 (58%). Before TUI, vesico-urete...

journal_title：BJU international

authors： Castagnetti M,Cimador M,Sergio M,de Grazia E

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women. PATIENTS AND METHODS:After a 1-week, placebo lead-in phase, 232 treatment-seeking women with regular menstrual cycles were randomly assigned to bupropion SR 150 mg/d...

journal_title：BJU international

authors： Safarinejad MR,Hosseini SY,Asgari MA,Dadkhah F,Taghva A

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To determine the value of gene-expression profiling as a predictor of the status of the regional nodes in patients with penile carcinoma. PATIENTS AND METHODS:Tumour samples of 56 patients with penile squamous cell carcinoma were analysed for the gene expression on 35 k oligoarrays; 32 were from patients wit...

journal_title：BJU international

authors： Kroon BK,Leijte JA,van Boven H,Wessels LF,Velds A,Horenblas S,van't Veer LJ

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To examine a large, single-surgeon series of patients with prostate cancer who underwent retropubic radical prostatectomy (RRP) for men with postoperative bladder neck contractures (BNCs). PATIENTS AND METHODS:From 1983 to 2007, 4132 men underwent RRP for prostate cancer by one surgeon. All patients had BN r...

journal_title：BJU international

authors： Erickson BA,Meeks JJ,Roehl KA,Gonzalez CM,Catalona WJ

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:To examine the results of open partial nephrectomy (OPN) over a 15-year period in a large UK teaching hospital and to compare results with other series including minimally invasive techniques, as nephron-sparing techniques are still under-utilized in the surgical treatment of renal carcinoma. A standardized ...

journal_title：BJU international

authors： Young JG,Luscombe CJ,Lynch C,Wallace DM

更新日期：2008-11-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? The clinical presentation and complications of lichen sclerosus are well known. What is less well known is the true incidence of the condition. The published figures are all based on attendance at general medical clinics or specialist clinics, but it ...

journal_title：BJU international

authors： Clouston D,Hall A,Lawrentschuk N

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To document the clinicopathological features of prostate cancer in a cohort of Jamaican men, and to determine which of these features are of prognostic significance in this population. PATIENTS AND METHODS:The clinical and pathological findings in 99 patients with prostate cancer (diagnosed consecutively aft...

journal_title：BJU international

authors： Shirley SE,Escoffery CT,Sargeant LA,Tulloch T

更新日期：2002-03-01 00:00:00

abstract：:For the delivery of good-quality external beam radiotherapy (EBRT) in localized prostate cancer, under-dosage to the peripheral zone (tumour) is one likely cause of poor results. The quality is improved by daily verification of the position of the prostate, and the use of magnetic resonance imaging (MRI) in delineatio...

journal_title：BJU international

authors： van Vulpen M,van der Heide UA,van Moorselaar JR

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To assess the durability of holmium laser enucleation of prostate in comparison to transurethral resection of the prostate (TURP). PATIENTS AND METHODS:Patients were enrolled in the present study between June 1997 and December 2000 and followed per protocol. All patients were urodynamically obstructed with a...

journal_title：BJU international

authors： Gilling PJ,Wilson LC,King CJ,Westenberg AM,Frampton CM,Fraundorfer MR

更新日期：2012-02-01 00:00:00

abstract：:What's known on the subject? and What does the study add? • Six targeted agents--sorafenib, sunitinib, pazopanib, bevacizumab, temsirolimus and everolimus--have been approved for the treatment of advanced renal cell carcinoma (RCC) based on evidence from large randomized controlled trials (RCTs). However, no head-to-h...

journal_title：BJU international

authors： Bellmunt J,Eisen T,Szczylik C,Mulders P,Porta C

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of comorbidity among patients with prostate cancer in relation to tumour and patient characteristics and to assess if comorbidity was a determining factor in the treatment choice for patients with localized prostate cancer. PATIENTS AND METHODS:Serious comorbidity was recorded in t...

journal_title：BJU international

authors： Post PN,Kil PJ,Hendrikx AJ,Janssen-Heijnen ML,Crommelin MA,Coebergh JW

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:To determine the feasibility and efficacy of suicide-gene therapy using adenovirus (Ad)-mediated herpes simplex virus thymidine kinase (HSV-TK) and the prodrug acyclovir, and to evaluate changes in the biological phenotype for tumour cell proliferative activity after suicide-gene therapy in animal models of ...

journal_title：BJU international

authors： Cheon J,Kim HK,Moon DG,Yoon DK,Cho JH,Koh SK

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:To investigate scores and predictors of patient satisfaction at 1 year after penile prosthesis implantation (PPI) using the validated Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) questionnaire. PATIENTS AND METHODS:Analyses were performed for 142 patients prospectively included in the natio...

journal_title：BJU international

authors： Capogrosso P,Pescatori E,Caraceni E,Mondaini N,Utizi L,Cai T,Salonia A,Palmieri A,Deho' F

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:• To evaluate the safety and efficacy of once-daily trospium chloride extended release (ER) in overactive bladder syndrome (OAB) in subjects aged ≥ 75 years. SUBJECTS AND METHODS:• The analysis included subjects ≥ 75 years of age with OAB. • A subgroup analysis of pooled data was performed for subjects aged ...

journal_title：BJU international

authors： Sand PK,Johnson Ii TM,Rovner ES,Ellsworth PI,Oefelein MG,Staskin DR

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To characterise the clinical, radiological and histological features of mucinous tubular and spindle cell carcinoma (MTSCC), as well as oncological outcomes. PATIENTS AND METHODS:This is a single institution retrospective analysis of all patients with MTSCC from 2002 to 2011. Patients were excluded if MTSCC ...

journal_title：BJU international

authors： Kenney PA,Vikram R,Prasad SR,Tamboli P,Matin SF,Wood CG,Karam JA

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To evaluate whether the degree of preoperative bladder trabeculation in neurogenic bladder (NB) patients is a marker of significant outlet resistance. If so, severe trabeculation may obviate the need for concomitant bladder outlet procedure (BOP) during augmentation cystoplasty (AC). PATIENTS AND METHODS:We ...

journal_title：BJU international

authors： Khoury AE,Dave S,Peralta-Del Valle MH,Braga LH,Lorenzo AJ,Bägli D

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To evaluate long-term recurrence-free and progression-free survival of noninvasive bladder tumours (stage Ta), and the significance of simple risk factors, including concomitant epithelial dysplasia. PATIENTS AND METHODS:The study included 217 patients with primary noninvasive bladder tumour (stage Ta) who w...

journal_title：BJU international

authors： Zieger K,Wolf H,Olsen PR,Hojgaard K

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To present the oncological and functional outcomes of salvage focal (SFC) and salvage total (STC) cryoablation for recurrent prostate cancer (PCa) after failed primary radiotherapy. PATIENTS AND METHODS:From March 2003 to August 2010, 50 men with biopsy-proven unilateral (n = 25) or bilateral (n = 25) radio...

journal_title：BJU international

authors： de Castro Abreu AL,Bahn D,Leslie S,Shoji S,Silverman P,Desai MM,Gill IS,Ukimura O

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To investigate the detection rate and extent of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical glands (AG) suspicious for prostate cancer, and the cancer risk in subsequent biopsies, diagnosed by a first 24-core saturation biopsy, as although the optimum extent of biopsy is controversial ...

journal_title：BJU international

authors： Schoenfield L,Jones JS,Zippe CD,Reuther AM,Klein E,Zhou M,Magi-Galluzzi C

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:To explore the role of transient receptor potential vanilloid 1 (TRPV1) in the excitatory effects of chronic administration of nerve growth factor (NGF) on bladder-generated sensory input and reflex activity. To explore new therapeutic targets for bladder dysfunction. MATERIALS AND METHODS:Wild-type (WT) an...

journal_title：BJU international

authors： Frias B,Charrua A,Avelino A,Michel MC,Cruz F,Cruz CD

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the natural history of a group of patients who underwent contact laser prostatectomy or transurethral resection of the prostate (TURP). PATIENTS AND METHODS:Patients were followed up at 5 years after enrolling in a prospective double-blind randomized controlled trial of TURP vs contact laser pros...

journal_title：BJU international

authors： Keoghane SR,Sullivan ME,Doll HA,Kourambas J,Cranston DW

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and clinical outcome of extracorporeal shock-wave therapy (ESWT) for patients suffering from chronic pelvic pain syndrome (CPPS). PATIENTS AND METHODS:The study included 34 patients who had had CPPS for >or=3 months, who were investigated in two subsequent studies. ESWT was adm...

journal_title：BJU international

authors： Zimmermann R,Cumpanas A,Hoeltl L,Janetschek G,Stenzl A,Miclea F

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To assess the clinical effect of the 'prostatic urethral lift' (PUL) on lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) through a crossover design study. PATIENTS AND METHODS:Men aged ≥ 50 years with an International Prostate Symptom Score of ≥ 13, a maximum urinary flo...

journal_title：BJU international

authors： Cantwell AL,Bogache WK,Richardson SF,Tutrone RF,Barkin J,Fagelson JE,Chin PT,Woo HH

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess the potentiation of erectile responses induced by electrical stimulation (ES) of the dorsal penile nerve (DPN) in the urethane-anaesthetized rat by the selective melanocortin receptor 4 agonist MB243. MATERIALS AND METHODS:Intracavernosal and blood pressures (ICP and BP, respectively) were monitore...

journal_title：BJU international

authors： Allard J,Reynolds DS,Edmunds NJ

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To describe a 25-year experience of using the Whitaker test in a single tertiary centre for assessing upper urinary tract dilatation, and to evaluate the role of perfusion pressure-flow studies in contemporary urological surgery for equivocal upper tract obstruction. PATIENTS AND METHODS:In all, 143 patients...

journal_title：BJU international

authors： Lupton EW,George NJ

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Extracorporeal shockwave lithotripsy is effective for the treatment of paediatric renal stones with favourable short-term safety. Extracorporeal shockwave lithotripsy for treatment of paediatric renal stones is also safe for the kidney and the child ...

journal_title：BJU international

authors： El-Nahas AR,Awad BA,El-Assmy AM,Abou El-Ghar ME,Eraky I,El-Kenawy MR,Sheir KZ

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:To describe the most recent data from phase I and II clinical trials of stereotactic body radiation therapy (SBRT) using image-guided robotic radiosurgery, specifically the Cyberknife(®) (Accuracy Incorporated, Sunnyvale, CA, USA). To better determine thecurrent role of this type of radiosurgery in prostate ...

journal_title：BJU international

authors： Seisen T,Drouin SJ,Phé V,Parra J,Mozer P,Bitker MO,Cussenot O,Rouprêt M

更新日期：2013-05-01 00:00:00