Comorbidity in patients with prostate cancer and its relevance to treatment choice.

Abstract:

OBJECTIVE:To evaluate the prevalence of comorbidity among patients with prostate cancer in relation to tumour and patient characteristics and to assess if comorbidity was a determining factor in the treatment choice for patients with localized prostate cancer. PATIENTS AND METHODS:Serious comorbidity was recorded in the Eindhoven Cancer Registry (according to a published list of such diseases) for all patients (2941) with prostate cancer newly diagnosed between 1993 and 1996 in the southern part of The Netherlands. Logistic regression was then used to assess which factors determined the treatment choice. RESULTS:The prevalence of at least one serious comorbid condition was 38% for patients aged 60-69 years, 48% when aged 70-74 years and 53% for those aged >/=75 years, the cardiovascular and chronic obstructive lung diseases being most frequent. Patients aged 60-69 years were more likely to be treated with radical prostatectomy for moderately differentiated tumour confined to the prostate, or when younger and diagnosed in a hospital with a high case-load. The presence of comorbidity had little influence of this choice. CONCLUSION:Comorbidity was common in patients with prostate cancer, but the decision of urologists in the southern Netherlands to use radical prostatectomy was determined largely by the patient's age and the urologist's experience.

journal_name

BJU Int

journal_title

BJU international

authors

Post PN,Kil PJ,Hendrikx AJ,Janssen-Heijnen ML,Crommelin MA,Coebergh JW

doi

10.1046/j.1464-410x.1999.00279.x

keywords:

subject

Has Abstract

pub_date

1999-10-01 00:00:00

pages

652-6

issue

6

eissn

1464-4096

issn

1464-410X

pii

bju279

journal_volume

84

pub_type

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