Adenovirus-mediated suicide-gene therapy using the herpes simplex virus thymidine kinase gene in cell and animal models of human prostate cancer: changes in tumour cell proliferative activity.

abstract：OBJECTIVE:To describe a 25-year experience of using the Whitaker test in a single tertiary centre for assessing upper urinary tract dilatation, and to evaluate the role of perfusion pressure-flow studies in contemporary urological surgery for equivocal upper tract obstruction. PATIENTS AND METHODS:In all, 143 patients...

journal_title：BJU international

authors： Lupton EW,George NJ

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To report the use of a novel donor source as a further option to increase the number of patients who might be able to receive a renal transplant. PATIENTS AND METHODS:Between May 1996 and July 2007, 43 kidneys were transplanted using kidneys obtained from patients with small (<3 cm diameter) incidentally det...

journal_title：BJU international

authors： Nicol DL,Preston JM,Wall DR,Griffin AD,Campbell SB,Isbel NM,Hawley CM,Johnson DW

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder. PATIENTS AND METHODS:The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was f...

journal_title：BJU international

authors： Yadav SS,Sadadukhi TC,Sharma KK,Yadav RG,Mathur R

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To investigate the expression of thymidylate synthase (TS), a key enzyme in DNA synthesis that is over-expressed in several cancer cells, in bladder cancer and its association with patient prognosis and the response to adjuvant therapy. PATIENTS AND METHODS:In all, 67 bladder tissue specimens were obtained f...

journal_title：BJU international

authors： Li Y,Li X,Dai H,Sun X,Li J,Yang F,Gu H,Yang Y,Jin Z,Chu Y,Jin X,Kakehi Y,Wu X

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To assess the impact on patterns of recurrence of adjuvant chemotherapy in patients with stage 1 nonseminomatous germ cell tumours (NSGCT) of the testis, who have a high likelihood of relapse on surveillance if certain risk factors are identified in the orchidectomy specimen, and thus the theoretical need for...

journal_title：BJU international

authors： Hendry WF,Norman A,Nicholls J,Dearnaley DP,Peckham MJ,Horwich A

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of the learning curve on operative, postoperative, and pathological outcomes of the first 67 totally intracorporeal robot-assisted radical cystectomies (RARCs) with neobladders performed by two lead surgeons at Karolinska University Hospital. PATIENTS AND METHODS:Between December 2003 ...

journal_title：BJU international

authors： Collins JW,Tyritzis S,Nyberg T,Schumacher MC,Laurin O,Adding C,Jonsson M,Khazaeli D,Steineck G,Wiklund P,Hosseini A

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To report our 5-year experience with laparoscopic and percutaneous cryoablation (LCA and PCA) for managing small renal masses. PATIENTS AND METHODS:We retrospectively analysed patients undergoing LCA and PCA between October 2000 and March 2006 at our institution. After approval from the Institutional Review ...

journal_title：BJU international

authors： Bandi G,Wen CC,Hedican SP,Moon TD,Lee FT Jr,Nakada SY

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...

journal_title：BJU international

authors： Danforth TL,Lane BR,Novick AC

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:To examine the effect of partial urethral obstruction (PUO) on bladder smooth muscle outward potassium current and the contribution of the large-conductance calcium-activated potassium (Maxi-K, BKCa) channel to this activity in smooth muscle cells isolated from bladders of sham-operated and PUO male rats usi...

journal_title：BJU international

authors： Aydin M,Wang HZ,Zhang X,Chua R,Downing K,Melman A,DiSanto ME

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To explore the effect of intravesical instillation of green tea extract (GTE) on a rat model of bacterial cystitis. MATERIALS AND METHODS:In vitro bactericidal properties of GTE were analysed by adding GTE to a suspension of uropathogenic E. coli (UPEC), streaking on MacConkey agar, and incubating overnight....

journal_title：BJU international

authors： Rosenberg S,Horowitz R,Coppenhagen-Glazer S,Pizov G,Elia A,Gofrit ON,Ginsburg I,Pode D

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To accurately define the anatomy of the neurovascular bundle (NVB) in men. MATERIALS AND METHODS:The NVB was microdissected in detail bilaterally in 12 fixed human male adult cadavers. The anatomy of the NVB and its relationship to surrounding pelvic structures was ascertained in each specimen. RESULTS:Prev...

journal_title：BJU international

authors： Costello AJ,Brooks M,Cole OJ

更新日期：2004-11-01 00:00:00

abstract：:We performed a systematic literature review to assess the current status of a totally intracorporeal robot-assisted radical cystectomy (RARC) approach. The current 'gold standard' for radical cystectomy remains open radical cystectomy. RARC has lagged behind robot-assisted prostatectomy in terms of adoption and percei...

journal_title：BJU international

authors： Collins JW,Wiklund NP

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To determine the sensitivity of the direct radionuclide cystogram (DRC) in detecting vesico-ureteric reflux compared with the micturating cysto-urethrogram (MCU) in the same initial setting, in infants younger than one year. PATIENTS AND METHODS:The results from the dual cystograms of 62 refluxing infants < ...

journal_title：BJU international

authors： McLaren CJ,Simpson ET

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To highlight the existence of Schistosoma haematobium in certain ethnic minority groups in Britain and in English citizens who have recently visited Africa and the Middle East, so that general practitioners and paediatric nephrologists/urologists are aware of its occurrence and consider it among the different...

journal_title：BJU international

authors： Samuel M,Misra D,Larcher V,Price E

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist (M3 SRA), from an analysis of pooled data from three phase III, multicentre, double-blind clinical trials in patients with overactive bladder (OAB). PATIENTS AND METHODS:After a 4-week washout/run-...

journal_title：BJU international

authors： Chapple C,Steers W,Norton P,Millard R,Kralidis G,Glavind K,Abrams P

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To determine if the adjunctive use of power Doppler imaging (PDI) could provide prognostic utility in the treatment of prostate cancer, as an accurate prediction of the clinical behaviour of prostate cancer is important to determine appropriate treatment. PATIENTS AND METHODS:Most centres rely on a digital r...

journal_title：BJU international

authors： Eisenberg ML,Cowan JE,Carroll PR,Shinohara K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:To investigate the receptors for angiotensin II (AII, reported to be a potent contractile agent in human urinary bladder), using functional and autoradiographic techniques in child and adult bladder specimens. Materials and methods Bladder specimens were obtained from 61 children (aged 4 months to 12 years) ...

journal_title：BJU international

authors： Lam DS,Dias LS,Moore KH,Burcher E

更新日期：2000-09-01 00:00:00

abstract：:The first two reviews are from the same unit in Germany and describe the well-known but still much discussed ways of improving the prognosis of patients undergoing cystectomy for bladder cancer. The authors review the roles of lymph node dissection and perioperative chemotherapy, and draw conclusions which will be of ...

journal_title：BJU international

authors： Suttmann H,Kamradt J,Lehmann J,Stöckle M

更新日期：2007-12-01 00:00:00

abstract：:To establish a set of consensus statements to facilitate physician management strategies for patients with metastatic prostate cancer (mPCa) in Hong Kong. A local expert consensus was organized jointly by the two main professional organizations representing prostate cancer specialists in Hong Kong. A total of 12 exper...

journal_title：BJU international

authors： Poon DM,Chan CK,Chan TW,Cheung FY,Kwong PW,Lee EK,Leung AK,Leung SY,Ma WK,So HS,Tam PC,Ho LY

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To assess fibroblast growth factor-2 (FGF2/bFGF), which is important in the development and maintenance of the normal prostate and in the development of human benign prostatic hyperplasia (BPH) and prostatic carcinoma, in an animal model of experimentally induced diabetes. Materials and methods Using Western ...

journal_title：BJU international

authors： Wang Z,Ikeda K,Wada Y,Foster HE,Weiss RM,Latifpour J

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To assess the cost, quality of life (QoL) and cost-effectiveness of a single-incision mini-sling (SIMS; Ajust(®) , C. R. Bard Inc., New Providence, NJ, USA) compared with a standard mid-urethral sling (SMUS; TVT-O™, Ethicon Inc., Somerville, NJ, USA) in the surgical management of female stress urinary incont...

journal_title：BJU international

authors： Boyers D,Kilonzo M,Mostafa A,Abdel-Fattah M

更新日期：2013-12-01 00:00:00

abstract：:OBJECTIVE To evaluate the indications for penile prosthesis implantation in the treatment of erectile dysfunction (ED) before and after the introduction of sildenafil. PATIENTS AND METHODS Penile prosthesis implantation was indicated in 144 men with ED at our institution between 1992 and 2007; 83 (55.6%) accepted the ...

journal_title：BJU international

authors： Cortés-González JR,Glina S

更新日期：2009-06-01 00:00:00

abstract：:Lower urinary tract symptoms (LUTS), benign prostatic obstruction (BPO), and the overactive bladder have increasing prevalence with age in both men and women (with the obvious exception). The question is, are they interrelated or independently related to age? The specific issue is whether BPO causes the overactive bla...

journal_title：BJU international

authors： Thomas AW,Abrams P

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of castration on the expression of endothelins (ETs), ET receptors and ET converting enzyme-1 (ECE-1) in the rat seminal vesicle (RSV). MATERIALS AND METHODS:Sprague-Dawley rats (3 months old) were surgically castrated or sham-operated, and then killed 7 days after surgery. Biochem...

journal_title：BJU international

authors： Takahashi W,Yono M,Wada Y,Ikeda K,Weiss RM,Latifpour J

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:To identify the rate of postoperative complications in patients who require surgical reconstruction for ketamine-induced urinary tract dysfunction and to identify any predictors for poor postoperative outcome with subsequent management strategies. PATIENTS AND METHODS:A retrospective review of data collecte...

journal_title：BJU international

authors： Sihra N,Ockrim J,Wood D

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To review the clinical and laboratory features and response to treatment of patients with acute brucellar epididymo-orchitis reporting to a tertiary care hospital in Riyadh, and to compare these with other cases reported previously. PATIENTS AND METHODS:In this retrospective study, records of all 26 adult pa...

journal_title：BJU international

authors： Memish ZA,Venkatesh S

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To investigate the possible protective role of insulin-like growth factor-1 (IGF-1, reported to have a protective effect in experimental models of hypoxic ischaemia), and the involvement of apoptotic cell death in a model of torsion/detorsion of the rat testis. MATERIALS AND METHODS:Adult male Wistar rats we...

journal_title：BJU international

authors： Ozkurkcugil C,Yardimoglu M,Dalcik H,Erdogan S,Gokalp A

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of non-cancer mortality and CV morbidity and some of that excess risk has been attributed to the treatment they receive. ADT is an established treatment option ...

journal_title：BJU international

authors： Nobes JP,Langley SE,Klopper T,Russell-Jones D,Laing RW

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To report a large multi-institutional series of laparoendoscopic single-site (LESS) nephroureterectomy (NU). MATERIALS AND METHODS:Data on all cases of LESS-NU performed between 2008 and 2012 at 15 institutions were retrospectively gathered. The main demographic data and perioperative outcomes were analysed....

journal_title：BJU international

authors： Park SY,Rha KH,Autorino R,Derweesh I,Liastikos E,Tsai YC,Seo IY,Nagele U,Abdel-Karim AM,Herrmann T,Han DH,Rais-Bahrami S,Lee SW,Kim KS,Fornara P,Kallidonis P,Springer C,Élsalmy S,Chueh SC,Ho CH,Panumatrassamee K,

更新日期：2013-09-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is among the most resistant tumours to chemotherapy, radiotherapy and hormonal therapy. Cytokine therapy is effective in a small subset of patients, but it is associated with substantial toxicity and rarely benefits patients with extensive tumour burdens or adverse prognostic factors. Since ...

journal_title：BJU international

authors： Mulders P

更新日期：2009-12-01 00:00:00