Direct comparison of radiology and nuclear medicine cystograms in young infants with vesico-ureteric reflux.

Abstract:

OBJECTIVE:To determine the sensitivity of the direct radionuclide cystogram (DRC) in detecting vesico-ureteric reflux compared with the micturating cysto-urethrogram (MCU) in the same initial setting, in infants younger than one year. PATIENTS AND METHODS:The results from the dual cystograms of 62 refluxing infants < 1 year old (mean 0.58) were compared. Results from same-day renal scintigraphy with dimercaptosuccinic acid (DMSA) in 60 of the 62 infants were also compared with the reflux grades. RESULTS:Reflux was detected in 105 units, 96 detected on the DRC and 47 on the MCU, representing a sensitivity of 91% and 45%, respectively. The DRC missed half of grade 1, 20% of grade 2 and 6% of grade 3 reflux. Reflux at low bladder filling rates (DRC) represented 40% of all reflux units, and a half (52%) of scarred renal units detected by DMSA scintigraphy. CONCLUSIONS:In young infants the MCU may fail to detect significant reflux and the DRC may fail to detect the lesser grades. The combination of both cystograms in the initial investigation of reflux provides more comprehensive information.

journal_name

BJU Int

journal_title

BJU international

authors

McLaren CJ,Simpson ET

doi

10.1046/j.1464-410x.2001.00997.x

keywords:

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

93-7

issue

1

eissn

1464-4096

issn

1464-410X

pii

bju997

journal_volume

87

pub_type

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