LRIG1, a candidate tumour-suppressor gene in human bladder cancer cell line BIU87.

abstract：OBJECTIVE:To evaluate the prevalence of depression, anxiety and distress among active surveillance (AS) and radical prostatectomy (RP) patients. To evaluate the impact of these symptoms at baseline on urinary and sexual quality of life at follow-up. PATIENTS AND METHODS:Patients managed with AS or RP who completed val...

journal_title：BJU international

authors： Punnen S,Cowan JE,Dunn LB,Shumay DM,Carroll PR,Cooperberg MR

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:•  To systematically review the current literature concerning perioperative, functional and oncological outcomes reported after open and minimally invasive prostate cancer surgery specifically from institutions within Australasia. MATERIALS AND METHODS:•  Four electronic databases were searched to identify s...

journal_title：BJU international

authors： Cathcart P,Murphy DG,Moon D,Costello AJ,Frydenberg M

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Pelvi-ureteric junction (PUJ) obstruction is characterized by a functionally significant impairment of urinary transport caused by intrinsic or extrinsic obstruction in the area where the ureter joins the renal pelvis. The majority of cases are congenital in origin; however, acquired conditions at the level ...

journal_title：BJU international

authors： Uberoi J,Disick GI,Munver R

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To review patients who had vesico-ureteric reflux corrected surgically by ureteric reimplantation during childhood, and thus assess their long-term outcome. PATIENTS AND METHODS:Between 1970 and 1979, 322 children underwent ureteric reimplantation; 100 (79 women and 21 men) were re-assessed and the long-term...

journal_title：BJU international

authors： Mor Y,Leibovitch I,Zalts R,Lotan D,Jonas P,Ramon J

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To assess the clinical pattern of progression and prostate-specific antigen doubling time (PSA-DT) after exposure to docetaxel-based chemotherapy in patients with androgen-independent prostate cancer (AIPC). PATIENTS AND METHODS:Fifty-five patients received docetaxel-based chemotherapy; data were collected r...

journal_title：BJU international

authors： Sella A,Sternberg C,Kovel S,Yarom N,Skoneczna I

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...

journal_title：BJU international

authors： Danforth TL,Lane BR,Novick AC

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:To report several samples of invasive human prostate cancer showing angiotropism, and to use human prostate cancer cells stably expressing green fluorescence protein (GFP) in in vitro and in vivo models to assess the dissemination pathway of prostate cancer cells. MATERIALS AND METHODS:Malignant melanoma an...

journal_title：BJU international

authors： Lugassy C,Vernon SE,Warner JW,Le CQ,Manyak M,Patierno SR,Barnhill RL

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:To determine whether modified transperineal template prostate-mapping (TTPM) biopsy protocols, altering the template or the biopsy density, have sensitivity and negative predictive value (NPV) equal to full 5-mm TTPM. PATIENTS AND METHODS:Retrospective analysis of an institutional registry including treatme...

journal_title：BJU international

authors： Valerio M,Anele C,Charman SC,van der Meulen J,Freeman A,Jameson C,Singh PB,Emberton M,Ahmed HU

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To examine the effects of mirabegron, a selective β3 -adrenoceptor agonist that has recently been approved for the treatment of overactive bladder (OAB), on erectile function. Stimulation of β3 -adrenoceptors localised in cavernosal smooth muscle cells may play a physiological role in mediating penile erectio...

journal_title：BJU international

authors： Gur S,Peak T,Yafi FA,Kadowitz PJ,Sikka SC,Hellstrom WJ

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To determine if the adjunctive use of power Doppler imaging (PDI) could provide prognostic utility in the treatment of prostate cancer, as an accurate prediction of the clinical behaviour of prostate cancer is important to determine appropriate treatment. PATIENTS AND METHODS:Most centres rely on a digital r...

journal_title：BJU international

authors： Eisenberg ML,Cowan JE,Carroll PR,Shinohara K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To verify the sensitivity of the bladder tumour antigen (BTAstat, Bard Urological, Covington, GA) test against the sensitive procedure of photodynamic diagnosis (PDD), in which 5-aminolaevulinic acid (5-ALA, a precursor of fluorescent porphyrins) is absorbed by the tumour and detected by ultraviolet cystoscop...

journal_title：BJU international

authors： Lipinski M,Jeromin L

更新日期：2002-05-01 00:00:00

abstract：:What's known on the subject? and What does the study add? • Six targeted agents--sorafenib, sunitinib, pazopanib, bevacizumab, temsirolimus and everolimus--have been approved for the treatment of advanced renal cell carcinoma (RCC) based on evidence from large randomized controlled trials (RCTs). However, no head-to-h...

journal_title：BJU international

authors： Bellmunt J,Eisen T,Szczylik C,Mulders P,Porta C

更新日期：2011-04-01 00:00:00

abstract：UNLABELLED:Study Type--Clinical (prospective trial) Level of Evidence 2b. What's known on the subject? and What does the study add? In clinical practice, we know that it is necessary to identify new biomarkers that can better detect prostate cancer (PC), at the same time as reducing the number of unnecessary biopsies. ...

journal_title：BJU international

authors： Sciarra A,Panebianco V,Cattarino S,Busetto GM,De Berardinis E,Ciccariello M,Gentile V,Salciccia S

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of oxidized cellulose, Surgicel(TM) (Johnson & Johnson Medical, New Brunswick, NJ, USA) for patching defects in the tunica albuginea in a rabbit model, with a future application to correct chordee. MATERIALS AND METHODS:The study comprised nine New Zealand white male rabbits; a recta...

journal_title：BJU international

authors： El-Assmy A,Eassa W,El-Hamid MA,Nour EM,Hafez AT

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To assess the possible relationship between treatment with selective serotonin-reuptake inhibitors (SSRIs) and the occurrence of nocturia. SUBJECTS AND METHODS:An unselected group of adult men and women, living in the city of Ostersund, Sweden, were sent a postal questionnaire containing questions on somatic...

journal_title：BJU international

authors： Asplund R,Johansson S,Henriksson S,Isacsson G

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:To compare targeted, transperineal magnetic resonance imaging (MRI)/ultrasound (US)-fusion biopsy to systematic transrectal biopsy in patients with previous negative or first prostate biopsy and to evaluate the gain in diagnostic information with systematic biopsies in addition to targeted MRI/US-fusion biop...

journal_title：BJU international

authors： Borkowetz A,Platzek I,Toma M,Laniado M,Baretton G,Froehner M,Koch R,Wirth M,Zastrow S

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:To determine the risk of failure during drug development in castration-resistant prostate cancer (CRPC) and to identify factors that could improve outcomes. METHODS:We investigated CRPC by analysing compounds in phase I to phase III clinical trials between 1998 and April 2011. Drug development failures were...

journal_title：BJU international

authors： Tenuta A,Klotz L,Parker JL

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To determine the prognostic utility of the cell cycle progression (CCP) score in men with National Comprehensive Cancer Network (NCCN)-defined low-risk prostate cancer (PCa) undergoing radical prostatectomy (RP). PATIENTS AND METHODS:Men who underwent RP for Gleason score ≤6 PCa at three institutions (Marti...

journal_title：BJU international

authors： Tosoian JJ,Chappidi MR,Bishoff JT,Freedland SJ,Reid J,Brawer M,Stone S,Schlomm T,Ross AE

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To investigate the distribution of c-kit-positive interstitial cells of Cajal (ICCs) in normal bladder and bladders from patients with megacystis-microcolon-intestinal peristalsis syndrome (MMIHS, a rare congenital and generally fatal cause of functional intestinal obstruction in the newborn), the most charac...

journal_title：BJU international

authors： Piaseczna Piotrowska A,Rolle U,Solari V,Puri P

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of patient age with pathological and long-term oncological outcomes after radical cystectomy (RC) for bladder carcinoma, as this disease, like many others, increases in incidence with age. PATIENTS AND METHODS:We retrospectively reviewed 241 consecutive patients with invasive blad...

journal_title：BJU international

authors： Resorlu B,Beduk Y,Baltaci S,Ergun G,Talas H

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:• To evaluate the safety and efficacy of once-daily trospium chloride extended release (ER) in overactive bladder syndrome (OAB) in subjects aged ≥ 75 years. SUBJECTS AND METHODS:• The analysis included subjects ≥ 75 years of age with OAB. • A subgroup analysis of pooled data was performed for subjects aged ...

journal_title：BJU international

authors： Sand PK,Johnson Ii TM,Rovner ES,Ellsworth PI,Oefelein MG,Staskin DR

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:To examine the efficacy of intralesional collagenase Clostridium histolyticum (CCH) in defined subgroups of patients with Peyronie's disease (PD). PATIENTS AND METHODS:The efficacy of CCH compared with placebo, assessed from baseline to week 52, was examined in subgroups of participants from the Investigati...

journal_title：BJU international

authors： Lipshultz LI,Goldstein I,Seftel AD,Kaufman GJ,Smith TM,Tursi JP,Burnett AL

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To assess the clinical effect of the 'prostatic urethral lift' (PUL) on lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) through a crossover design study. PATIENTS AND METHODS:Men aged ≥ 50 years with an International Prostate Symptom Score of ≥ 13, a maximum urinary flo...

journal_title：BJU international

authors： Cantwell AL,Bogache WK,Richardson SF,Tutrone RF,Barkin J,Fagelson JE,Chin PT,Woo HH

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the International Prostate Symptom Score (IPSS) bother question (BQ) and a validated disease-specific quality-of-life questionnaire, the Benign Prostatic Hyperplasia (BPH) Impact Index (BPH-II), using the BPH Registry and Patient Survey database. PATIENTS AND METHODS:The B...

journal_title：BJU international

authors： O'Leary MP,Wei JT,Roehrborn CG,Miner M,BPH Registry and Patient Survey Steering Committee.

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To determine, using magnetic resonance imaging (MRI), the incidence of retropubic haematoma and any associated clinically significant effects after a xenograft (porcine dermis) sling (XS) or the tension-free vaginal tape (TVT) procedure. PATIENTS AND METHODS:Between October 2003 and March 2004, 24 consecutiv...

journal_title：BJU international

authors： Giri SK,Wallis F,Drumm J,Saunders JA,Flood HD

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess the use of mitomycin C, by urologists within the UK, as a single-dose intravesical agent. Current European recommendations are to use one dose after any new tumour resection. METHODS:We assessed the current patterns of mitomycin C usage amongst British urologists, particularly with reference to one...

journal_title：BJU international

authors： Clarke NS,Basu S,Prescott S,Puri R

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To assess the overall and disease-specific survival rates of patients undergoing robot-assisted radical cystectomy (RARC) compared with historical open cystectomy. PATIENTS AND METHODS:Survival, pathological and demographic data were collected on all patients undergoing RARC for bladder cancer from both Tula...

journal_title：BJU international

authors： Martin AD,Nunez RN,Pacelli A,Woods ME,Davis R,Thomas R,Andrews PE,Castle EP

更新日期：2010-06-01 00:00:00

abstract：:Accurate prediction is essential for patient counselling, appropriate selection of treatments and determination of eligibility for clinical trials. In this review we assess the available determinants of oncological outcome after radical cystectomy (RC) for transitional cell carcinoma of the urinary bladder. We reviewe...

journal_title：BJU international

authors： Margulis V,Lotan Y,Montorsi F,Shariat SF

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To validate a hypothesis that prostate cancer can be detected non-invasively by a simple and reliable assay by targeting genomic VPAC receptors expressed on malignant prostate cancer cells shed in voided urine. PATIENTS/SUBJECTS AND METHODS:VPAC receptors were targeted with a specific biomolecule, TP4303, de...

journal_title：BJU international

authors： Trabulsi EJ,Tripathi SK,Gomella L,Solomides C,Wickstrom E,Thakur ML

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:• To present a novel method of renal ablation using direct current electrolysis, using a porcine model to assess the safety and efficacy of the technique. MATERIALS AND METHODS:• In all, 20 anaesthetised pigs were used, after receiving ethical approval. The pigs were housed and managed in accordance with Ins...

journal_title：BJU international

authors： Lloyd M,Miller J,Moretti KL,Texler M,Maddern GJ

更新日期：2012-12-01 00:00:00