Abstract:
OBJECTIVE:To evaluate the prevalence of depression, anxiety and distress among active surveillance (AS) and radical prostatectomy (RP) patients. To evaluate the impact of these symptoms at baseline on urinary and sexual quality of life at follow-up. PATIENTS AND METHODS:Patients managed with AS or RP who completed validated questionnaires assessing levels of depression, anxiety, distress and urinary (UF) and sexual function (SF) and bother comprised the final analytic cohort. These measures were completed at baseline, within 1 year, and between 1 and 3 years from baseline. Mixed model repeated measures analysis was used to examine associations between mental health at baseline and sexual and urinary outcomes in a subset of RP patients with complete follow-up. RESULTS:Among 679 men who comprised the study cohort, baseline prevalence of moderate or higher levels of depression or anxiety were low (<5%), while levels of mild depression or anxiety ranged from 3-16% over time. Baseline levels of elevated distress ranged from 8-20%. Among men who provided data at baseline and follow-up, there were no significant differences between AS and RP patients in the proportion of men with elevated levels of depression, anxiety, or distress. Among 177 men who underwent RP and had complete follow-up moderate or higher levels of depression or anxiety appeared to be associated with post-treatment SF and bother, while elevated levels of distress were associated with post-treatment UF. CONCLUSION:Moderate or higher levels of depression or anxiety were low in men with localised prostate cancer but were associated with sexual outcomes, while elevated distress was associated with urinary outcomes. Greater attention should be paid to mental health symptoms among men with prostate cancer, as these symptoms may be associated with quality of life outcomes.
journal_name
BJU Intjournal_title
BJU internationalauthors
Punnen S,Cowan JE,Dunn LB,Shumay DM,Carroll PR,Cooperberg MRdoi
10.1111/bju.12209subject
Has Abstractpub_date
2013-07-01 00:00:00pages
E67-75issue
2eissn
1464-4096issn
1464-410Xjournal_volume
112pub_type
杂志文章abstract:OBJECTIVE:To characterize the clinicopathological findings and the outcome of human immunodeficiency virus (HIV)-infected patients diagnosed and treated for prostate carcinoma, as HIV-positive men being treated with highly active antiretroviral therapy (HAART) are living longer and thus are more likely to develop cance...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2008.07474.x
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the long-term outcome in children who had an artificial urinary sphincter (AUS) placed, after a minimum of 10 years of follow-up. PATIENTS AND METHODS:The medical records of patients who had an AUS placed at the Children's Hospital of Michigan were reviewed and a telephone questionnaire was then ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00077.x
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To determine the value of measuring serum concentrations of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in patients with benign prostatic hyperplasia (BPH), advanced and localized prostate cancer, and thus assess the role of angiogenesis factors as markers of malignancy...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00363.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To assess the rate of prostate-specific antigen (PSA) testing for prostate cancer in general practice in asymptomatic and symptomatic patients. SUBJECTS AND METHODS:The cross-sectional study took place in England and Wales, was population-based and covered 469 159 men aged 45-84 years. Pathology data on PSA ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-4096.2004.04832.x
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To describe the most recent data from phase I and II clinical trials of stereotactic body radiation therapy (SBRT) using image-guided robotic radiosurgery, specifically the Cyberknife(®) (Accuracy Incorporated, Sunnyvale, CA, USA). To better determine thecurrent role of this type of radiosurgery in prostate ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/bju.12000
更新日期:2013-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13611
更新日期:2017-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10406.x
更新日期:2012-02-01 00:00:00
abstract::The immediate objective of phosphodiesterase type 5 (PDE5) inhibitor treatment is to restore the ability of a man to achieve and/or maintain an erection adequate for sexual intercourse. As erectile dysfunction (ED) generally develops in the second half of life, the ultimate objective generally is not procreation, but ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2008.08267.x
更新日期:2009-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08984.x
更新日期:2010-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.05870.x
更新日期:2006-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13411
更新日期:2016-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05993.x
更新日期:2006-03-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11042.x
更新日期:2012-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00844.x
更新日期:1999-01-01 00:00:00
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doi:10.1111/bju.12890
更新日期:2015-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.06754.x
更新日期:2007-05-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1111/bju.13124
更新日期:2016-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/bju.12747
更新日期:2015-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07046.x
更新日期:2007-10-01 00:00:00
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doi:10.1111/bju.12517
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pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00966.x
更新日期:2000-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04009.x
更新日期:2003-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04429.x
更新日期:2003-10-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.2441.x
更新日期:2001-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1046/j.1464-410x.2003.04378.x
更新日期:2003-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.06871.x
更新日期:2007-07-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2018-02-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.09118.x
更新日期:2010-07-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.13096
更新日期:2015-10-01 00:00:00