Abstract:
OBJECTIVE:To develop and validate an Arabic version of the International Prostate Symptom Score (IPSS). PATIENTS, SUBJECTS AND METHODS:An Arabic version of the IPSS (IPSS-Arb) was developed through a series of translations and modifications which involved the authors, urology and non-urology medical and nursing staff. The validity and reliability were assessed in 76 patients with urinary symptoms due to benign prostatic hyperplasia (BPH) and in 63 control subjects without BPH; 25 patients had transurethral resection of prostate (TURP) whereas the remaining 51 patients were treated with terazosin. The reliability of the IPSS-Arb was assessed by determining the internal consistency (Cronbach's alpha coefficient) and by assessing the test-retest reliability (intraclass correlation coefficient, ICC). Construct validity was assessed by determining the correlation between the IPSS-Arb scores and the quality-of-life question (QoL-Arb), and by determining the ability of the IPSS-Arb to discriminate between the patients and controls by calculating the area under the receiver operating characteristic (ROC) curve. RESULTS:The Cronbach's alpha coefficient (internal consistency) for the IPSS-Arb was 0.85, and 0.78-0.88 for the individual items. The test-retest reliability (ICC) was 0.88 (P < 0.001). In addition, the IPSS-Arb had a high correlation with the QoL-Arb (Spearman rank correlation coefficient 0.82, P = 0.01). The mean (sem, 95% confidence interval) area under the ROC curve for the IPSS-Arb was 0.93 (0.09, 0.89-0.97), whereas the area for its individual questions was 0.79-0.90. The IPSS-Arb also showed a high sensitivity to change. The mean (sd) IPSS-Arb scores before and after TURP were 23.1 (6.4) and 6.9 (1.8), respectively (P < 0.001); in the terazosin group, the scores were 12.6 (7.4) and 8.2 (4.0), respectively (P < 0.001). CONCLUSIONS:The IPSS-Arb was shown to be a reliable and valid instrument for patients with BPH. We recommend using it for patient assessment and follow-up, and as a research tool in Arabic-speaking patients both in the Middle East and worldwide. In addition, this study provided another proof of the wide suitability of the IPSS among various nations worldwide.
journal_name
BJU Intjournal_title
BJU internationalauthors
Hammad FT,Kaya MAdoi
10.1111/j.1464-410X.2009.08984.xsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
1434-8issue
10eissn
1464-4096issn
1464-410Xpii
BJU8984journal_volume
105pub_type
杂志文章abstract:OBJECTIVE:To present the renal functional outcomes for patients treated with open partial nephrectomy (OPN) or radiofrequency ablation (RFA) for tumours in a solitary kidney, as renal masses in a solitary kidney present a challenging treatment dilemma. PATIENTS AND METHODS:A retrospective review of institutional datab...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2009.08776.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To optimise the diagnostic and phototherapeutic efficacy of hypericin in superficial bladder cancer, by developing a bladder instillation fluid that does not depend on the presence of plasma proteins for an appropriate and reliable urothelial uptake of hypericin. MATERIALS AND METHODS:Sodium hypericinate (in...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05316.x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To review the results of repairing a parastomal hernia after ileal conduit formation, using the lateral approach. PATIENTS AND METHODS:We retrospectively assessed 18 patients (9%) who developed a parastomal hernia, from 211 who had an ileal conduit created between 1982 and 2001; 15 had a surgical repair usin...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.05008.x
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the epidemiology of lower urinary tract symptoms (LUTS) among men and women, as there are significant unanswered questions about the prevalence and impact of LUTS in different populations. SUBJECTS AND METHODS:A population-based, cross-sectional survey was completed in Boxmeer (the Netherlands), ...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1464-410x.2003.04369.x
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of transcript profiling in diagnostic formalin-fixed and paraffin-embedded (FFPE) biopsies for prostate cancer. MATERIALS AND METHODS:Laser-capture microdissection (LCM) was used to microdissect glandular epithelium as well as stromal tissue in archival prostate needle biopsies...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07627.x
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To investigate the associations of host metabolic factors and metabolic syndrome on prostate cancer-specific death (PCSD) and overall survival (OS) in patients treated with androgen deprivation therapy (ADT) for biochemically recurrent disease. PATIENTS AND METHODS:The analysis included 273 patients with pr...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13428
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To report a simplified and effective method for substratification of M1 castrate-resistant prostate cancer (CRPC) by correlating progression-free (PFS) and overall survival (OS) with simple quantification of skeletal metastases. PATIENTS AND METHODS:In all, 561 men with M1 CRPC were studied longitudinally. I...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12717
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:• To evaluate whether current nephrectomy pathology reports are sufficient to allow clinicians to use prognostic nomograms, tailor surveillance, enroll patients into adjuvant trials and select systemic therapy for renal cell carcinoma (RCC). PATIENTS AND METHODS:• Nephrectomy pathology reports were obtained ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09871.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To investigate the high circumcision rate in South Korea and its rapid increase in the short period since its introduction. SUBJECTS AND METHODS:From January to December 2000, 5434 South Korean males (or their parents) aged 0-92 years were interviewed in detail about their circumcision status, their age at c...
journal_title:BJU international
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Tribute to Professor Pieter De Mulder, from Martin Gore. Pieter and I were often pitted against each other in debates at international meetings on the role of cytokine therapy. The truth is that there was little disagreement between us, but we both thought such set pieces were a good way to highlight the issues surrou...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2008.07435.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To assess the potential use of bone marrow stromal cell (BMSC)-seeded biodegradable scaffold for bladder regeneration in a canine model, by characterizing BMSCs and comparing them to bladder smooth muscle cells (SMCs) by immunohistochemistry, growth capability, and contractility. MATERIALS AND METHODS:Bone m...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05741.x
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To identify the outcome of nephrectomy and predictors of hypertension (HTN) resolution in children with poorly functioning unilateral kidneys (differential renal function, DRF of < 15%), as concurrent HTN is often an indication for nephrectomy. PATIENTS AND METHODS:Over a 7.5-year period, a single centre ret...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09308.x
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:To assess the activity of baclofen, a potent gamma-aminobutyric acid-ergic agonist, against dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS) in a clinical trial, as DV is a leading cause of LUTS in women, but there is no effective treatment. PATIENTS AND METHODS:We conducted a randomized d...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2007.06987.x
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To report the surgical treatment of patients with renal cell carcinoma (RCC) metastatic to the contralateral adrenal gland and compare our experience with previous reports, as such metastases are found in 2.5% of patients with metastatic RCC at autopsy, and the role of resecting metastatic RCC at this site is...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04237.x
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To study a novel penile reinnervation technique using four sural nerve grafts and end-to-side neurorraphies connecting bilaterally the femoral nerve and the cavernous corpus and the femoral nerve and the dorsal penile nerves. PATIENTS AND METHODS:Ten patients (mean [± sd; range] age 60.3 [± 4.8; 54-68] years...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13772
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To examine the correlation between partial bladder outlet obstruction (PBOO) and bladder carcinogenesis. MATERIALS AND METHODS:Female Wistar rats (6 weeks old) were divided into three groups of 10 each: group 1 was exposed to n-butyl-n-butanol nitrosamine (BBN, a carcinogen) in drinking water for 8 weeks; gr...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08261.x
更新日期:2009-05-01 00:00:00
abstract::What's known on the subject? and What does the study add? With recent improvements in the prognosis for patients with metastatic renal cell carcinoma (mRCC), focus is now shifting towards maximising clinical benefit from targeted therapies. Factors other than efficacy data are increasingly being considered when select...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11100.x
更新日期:2012-11-01 00:00:00
abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The various phenotypes of hypospadias may result from disturbances of dissimilar embryonic processes in different time windows, suggesting aetiological heterogeneity; however, only a few studies have investigated the risk factors for the different hy...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11745.x
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To identify a phenotype that could be informative and prognostic in patients with renal cell carcinoma (RCC) peripheral blood was evaluated for TH1, TH2, regulatory T cells (Tregs), natural killer (NK) and NKT cells and for cytokines/chemokines. PATIENTS AND METHODS:Peripheral blood from 77 patients with RCC...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12068
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To determine the adequacy of T2 prostate cancer (PCa) sub-staging as an independent Predictor of biochemical disease-free survival (bDFS) after radical prostatectomy. MATERIALS AND METHODS:The Duke Prostate Center database was queried for patients who underwent radical prostatectomy between 1988 and 2007 and...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09439.x
更新日期:2010-12-01 00:00:00
abstract::• Renal angiomyolipomas (AMLs) are usually easy to diagnose with imaging alone. They have unique characteristics on ultrasonography, computerised tomography and magnetic resonance imaging that usually allow AMLs to be differentiated from other renal masses. • If this is not possible on imaging criteria then biopsy can...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11618.x
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To characterise the clinical, radiological and histological features of mucinous tubular and spindle cell carcinoma (MTSCC), as well as oncological outcomes. PATIENTS AND METHODS:This is a single institution retrospective analysis of all patients with MTSCC from 2002 to 2011. Patients were excluded if MTSCC ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12992
更新日期:2015-07-01 00:00:00
abstract::The aim of revalidation (or maintenance of certification) is to reassure patients, the general public, employers and other healthcare professionals that an individual is fit to practice. It may lead to a reduction in near misses or adverse events. The process of revalidation entails a commitment to the provision of li...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2011.10375.x
更新日期:2011-10-01 00:00:00
abstract::Because of the heterogeneity of prostate cancer knowledge about the genes involved in prostate carcinogenesis is still very limited. Previously, the use of novel high-throughput technologies offered the possibility to investigate broad gene expression profiles and thus helped to improve understanding of the molecular ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2004.04869.x
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To develop a canine model of external urinary sphincter insufficiency by creating irreversible damage to the sphincter, because there is a need for a reliable and reproducible large animal model for the study of stress urinary incontinence (SUI) caused by deficient sphincter function. MATERIALS AND METHODS:A...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08001.x
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:• To report outcomes for patients with localized prostate cancer managed using a watchful waiting strategy at an American centre and to explore factors that have triggered intervention. PATIENTS AND METHODS:• From 1991 to 2005, 218 patients diagnosed with untreated localized prostate cancer were followed at ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09652.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To determine the partner's influence on the patient's choice of treatment for early prostate cancer, and whether partner characteristics and biases predict the preference. PATIENTS, SUBJECTS AND METHODS:Questionnaires for partners to complete retrospectively were sent to consecutive patients recruited in a s...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04355.x
更新日期:2003-09-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Recent studies have indicated that high mobility group box 1 (HMGB1) is related to the development and progression of human carcinomas. However, further studies were required to confirm the roles played by HMGB1 in clinical prostate cancer treatment. ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11277.x
更新日期:2012-12-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of non-cancer mortality and CV morbidity and some of that excess risk has been attributed to the treatment they receive. ADT is an established treatment option ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2011.10555.x
更新日期:2012-05-01 00:00:00
abstract::Laparoendoscopic single-site surgery (LESS) and natural orifice transluminal endoscopic surgery (NOTES™) are new approaches to minimally invasive surgery. A number of technical challenges need to be overcome and new developments of equipment are required before widespread acceptance of either modality occurs. In this ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09665.x
更新日期:2010-09-01 00:00:00