Watchful waiting for localized prostate cancer in the PSA era: what have been the triggers for intervention?

abstract：OBJECTIVE:To determine whether health-insurance status might result in more localized stage at presentation, more favourable stage at surgery and in a lower rate of biochemical recurrence (BCR), in patients diagnosed with prostate cancer and treated with radical prostatectomy (RP), as despite uninhibited access to heal...

journal_title：BJU international

authors： Gallina A,Karakiewicz PI,Chun FK,Briganti A,Graefen M,Montorsi F,Walz J,Jeldres C,Erbersdobler A,Salonia A,Suardi N,Dehò F,Schlomm T,Scattoni V,Haese A,Heinzer H,Valiquette L,Rigatti P,Huland H

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:• To investigate the relationship between pretreatment testosterone levels and pathological specimen characteristics, by prospectively examining serum androgen concentrations in a well-studied cohort of patients who underwent radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS:• A ...

journal_title：BJU international

authors： Xylinas E,Ploussard G,Durand X,Fabre A,Salomon L,Allory Y,Vordos D,Hoznek A,Abbou CC,de la Taille A

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To compare prospectively obtained symptom scores (pre-tests) with retrospective assessment (then-tests) in patients with newly diagnosed advanced prostate cancer. PATIENTS AND METHODS:Patients with newly diagnosed locally advanced or metastatic prostate cancer were recruited. They completed the International...

journal_title：BJU international

authors： Rees J,Waldron D,O'Boyle C,Ewings P,MacDonagh R

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury. MATERIALS AND METHODS:Given the great similarity between the anatomical structure of the cavernous nerve in rats and humans, 24 rats underwent dissections and the cavernous nerves were identified with the aid of an operating mi...

journal_title：BJU international

authors： Kaufmann O,Claro J,Cury J,Andrade E,Longo B,Aguiar W,Mello L,Srougi M

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To present our experience and outcome of consecutive laparoscopic renal biopsy over a 9-year period, as renal biopsy remains an important diagnostic procedure for evaluating proteinuria, haematuria and renal failure, but when percutaneous biopsy is contraindicated, a laparoscopic biopsy is an attractive opti...

journal_title：BJU international

authors： Shetye KR,Kavoussi LR,Ramakumar S,Fugita OE,Jarrett TW

更新日期：2003-06-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Prostate cancer has three known clinical risk factors: age, ethnicity and family history. Men's knowledge of prostate cancer is low. This study demonstrates that men rely on family and friends to learn about prostate cancer and help them interpret th...

journal_title：BJU international

authors： Forbat L,Place M,Kelly D,Hubbard G,Boyd K,Howie K,Leung HY

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:•To determine the optimal treatment for incidentally detected small renal masses between radical nephrectomy, partial nephrectomy, ablative therapy (AT) and active surveillance (AS) using a decision-analytic Markov model. SUBJECTS AND METHODS:•The reference case was an otherwise healthy 60-year-old patient. ...

journal_title：BJU international

authors： Abouassaly R,Yang S,Finelli A,Kulkarni GS,Alibhai SM

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of erectile dysfunction (ED) in a large cohort of Brazilian men who were screened for prostate cancer, and to determine risk factors in this population, as there are large cultural differences among countries in reporting the frequency of ED, and it is likely that the prevalence of...

journal_title：BJU international

authors： Paranhos M,Antunes A,Andrade E,Freire G,Srougi M

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To evaluate retrospectively the surgical, symptomatic and oncological outcomes of pelvic exenteration surgery (PES) in men with significant intrapelvic complications of locally advanced castration-sensitive (CSPC) and castration-resistant prostate cancer (CRPC). PATIENTS AND METHODS:A total of 103 patients ...

journal_title：BJU international

authors： Heidenreich A,Bludau M,Bruns C,Nestler T,Porres D,Pfister DJKP

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To compare the outcomes for laparoscopic vascular hitch (VH) and dismembered pyeloplasty in patients with pelvi-ureteric junction obstruction (PUJO) secondary to crossing vessels (CV). PATIENTS AND METHODS:Patients who underwent laparoscopic management of CV at our institution were identified between 2008 an...

journal_title：BJU international

authors： Kim JK,Keefe DT,Rickard M,Milford K,Lorenzo AJ,Chua ME

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:To assess the changing distribution of stage in seminoma and nonseminomatous germ cell tumours (NSGCTs), as recent reports contained no detailed information on pT stage and vascular invasion, important factors in the decision for further treatment. PATIENTS AND METHODS:Histopathological reports from 1976 to ...

journal_title：BJU international

authors： Lackner JE,Koller A,Mazal PR,Waldert M,Waldhoer T,Marberger M,Kratzik C

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To determine the role of hypoxia-inducible factor-2alpha (HIF2alpha) on the sensitivity of renal cell carcinoma (RCC) cell lines to ionizing radiation and to determine if the mTOR antagonist, rapamycin, could decrease HIF2alpha protein levels. MATERIALS AND METHODS:Cell lines expressing stable short-hairpin ...

journal_title：BJU international

authors： Bhatt RS,Landis DM,Zimmer M,Torregrossa J,Chen S,Sukhatme VP,Iliopoulos O,Balk S,Bubley GJ

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:To examine the effect of the dual-action 5alpha-reductase inhibitor dutasteride on benign prostatic hyperplasia (BPH)-specific health status, as measured by the BPH Impact Index (BII), and to identify baseline and treatment risk factors for those most bothered by their BPH symptoms at the end of the protocol...

journal_title：BJU international

authors： O'Leary MP,Roehrborn C,Andriole G,Nickel C,Boyle P,Höfner K

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To describe the preclinical pharmacology of Ro 115-1240, a peripherally acting selective alpha1A/1L-adrenoceptor (AR) partial agonist, compared with the alpha1A/1L-AR full agonist amidephrine, as AR agonists have some utility in the treatment of stress urinary incontinence (SUI) but are limited by undesirable...

journal_title：BJU international

authors： Blue DR,Daniels DV,Gever JR,Jett MF,O'Yang C,Tang HM,Williams TJ,Ford AP

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate the impact of race on the effectiveness of hormonal therapy in patients with prostate cancer, by comparing the outcomes of Caucasian men (CM) and Japanese-American men (JAM) treated with hormonal therapy at one institution. PATIENTS AND METHODS:Fifty-nine CM and 105 JAM with prostate cancer we...

journal_title：BJU international

authors： Fukagai T,Namiki TS,Carlile RG,Yoshida H,Namiki M

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To determine the metabolic characteristics of elderly patients with recurrent calcium oxalate stones. PATIENTS AND METHODS:Metabolic abnormalities were investigated in 88 patients with recurrent calcium oxalate stones, including 70 aged <60 years and 18 aged >/=60 years. The frequency of each metabolic abnor...

journal_title：BJU international

authors： Yagisawa T,Hayashi T,Yoshida A,Okuda H,Kobayashi H,Ishikawa N,Goya N,Toma H

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:• To investigate a new method of vas deferens radiography for ejaculatory duct obstruction (EDO). • To evaluate the effect of a procedure involving dilation of the ejaculatory duct by F9 seminal vesicoscopy. PATIENTS AND METHODS:• Twenty-two patients with EDO were diagnosed using semen analysis, semen fruct...

journal_title：BJU international

authors： Xu B,Niu X,Wang Z,Li P,Qin C,Li J,Liu B,Wang P,Jia Y,Wu H,Zhang W

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:to investigate the effect of menopausal transition and age on symptoms of urinary incontinence in midlife. SUBJECTS AND METHODS:the study included a nationally representative cohort of 1211 women followed up since their birth in 1946 and annually from 48-54 years; their menopausal transition status and sympt...

journal_title：BJU international

authors： Mishra GD,Cardozo L,Kuh D

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To determine the prognostic utility of the cell cycle progression (CCP) score in men with National Comprehensive Cancer Network (NCCN)-defined low-risk prostate cancer (PCa) undergoing radical prostatectomy (RP). PATIENTS AND METHODS:Men who underwent RP for Gleason score ≤6 PCa at three institutions (Marti...

journal_title：BJU international

authors： Tosoian JJ,Chappidi MR,Bishoff JT,Freedland SJ,Reid J,Brawer M,Stone S,Schlomm T,Ross AE

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...

journal_title：BJU international

authors： Schoeppler GM,Buchner A,Zaak D,Khoder W,Staehler M,Stief CG,Reiser MF,Clevert DA

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:To report an audit of preoperative staging variables, case selection, stage migration and prostate-specific antigen (PSA) recurrence at five large centres in the south of England. To establish PSA outcome values after radical prostatectomy for clinically localized prostate cancer in the UK, and enable approp...

journal_title：BJU international

authors： Winkler MH,Khan FA,Hoh IM,Okeke AA,Sugiono M,McInerney P,Boustead GB,Persad R,Kaisary AV,Gillatt DA

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To assess the potential use of bone marrow stromal cell (BMSC)-seeded biodegradable scaffold for bladder regeneration in a canine model, by characterizing BMSCs and comparing them to bladder smooth muscle cells (SMCs) by immunohistochemistry, growth capability, and contractility. MATERIALS AND METHODS:Bone m...

journal_title：BJU international

authors： Zhang Y,Lin HK,Frimberger D,Epstein RB,Kropp BP

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To characterize serial long-term histological changes in mesenchymal cells infiltrating a collagen-based matrix, as in a hollow organ with differentiated urothelial lining created intraperitoneally by grafting cultured urothelial cells, mesenchymal cells with smooth-muscle immunohistochemical characteristics ...

journal_title：BJU international

authors： Moriya K,Kakizaki H,Watanabe S,Sano H,Nonomura K

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To isolate new cDNAs corresponding to genes whose expression is increased during castration-induced rat prostate apoptosis. MATERIALS AND METHODS:Differential display of mRNAs from 3-day castrated and normal rat ventral prostates was used to identify differentially expressed clones. Northern blots were hybri...

journal_title：BJU international

authors： Bruyninx M,Ammar H,Reiter E,Cornet A,Closset J

更新日期：2000-06-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (cohort) Level of Evidence 2a. What's known on the subject? and What does the study add? Patient-reported quality of life (QoL) in prostate cancer is recognized as an important outcome, and has been shown in multiple studies to capture the incidence and timing of patient symptoms more acc...

journal_title：BJU international

authors： Chen RC,Zhang Y,Chen MH,McMahon E,Loffredo M,McPherson CP,Nguyen AU,Nguyen PL,D'Amico AV

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To examine differences in gene expression levels between renal cell carcinoma (RCC) tissue and 'normal' appearing renal tissue using a commercially available DNA macroarray. MATERIALS AND METHODS:Tissue was obtained from 47 consecutive radical nephrectomies, 29 of which were eligible. DNA macroarrays were an...

journal_title：BJU international

authors： Lovisolo JA,Casati B,Clerici L,Marafante E,Bono AV,Celato N,Salvadore M

更新日期：2006-07-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Systems for image guidance during laparoscopic surgery can be broadly defined as systems that enable the surgeon to refer to preoperatively gathered information during the procedure. For a laparoscopic system the preoperative information can be overl...

journal_title：BJU international

authors： Thompson S,Penney G,Billia M,Challacombe B,Hawkes D,Dasgupta P

更新日期：2013-06-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? L-dopa decarboxylase (DDC) has been documented as a novel co-activator of androgen receptor transcriptional activity. Recently, it was shown that DDC gene expression is significantly higher in patients with PCa than in those with BPH. In the present s...

journal_title：BJU international

authors： Koutalellis G,Stravodimos K,Avgeris M,Mavridis K,Scorilas A,Lazaris A,Constantinides C

更新日期：2012-09-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? There have been few studies evaluating the prognostic value of epithelial-mesenchymal transition markers in renal cell carcinoma (RCC); therefore, the significance of these markers in the prognosis of patients with RCC, particularly that in those with...

journal_title：BJU international

authors： Harada K,Miyake H,Kusuda Y,Fujisawa M

更新日期：2012-12-01 00:00:00

abstract：:Jim Peters, a country boy who excelled academically and in the sporting arena was a Victorian urological pioneer. His passion for teaching and belief in the development of Australasian urology resulted in the establishment of two of Melbourne's earliest Urology Units (which are now major academic University department...

journal_title：BJU international

authors： Webb DR

更新日期：2013-11-01 00:00:00