Prospective vs retrospective assessment of lower urinary tract symptoms in patients with advanced prostate cancer: the effect of 'response shift'.

abstract：OBJECTIVES:To use the Fragility Index to evaluate the robustness of statistically significant findings from urological randomised controlled trials (RCTs). MATERIALS AND METHODS:The 'Fragility Index' is defined as the minimum number of patients in one arm of a trial whose status would have to change from 'event' to 'n...

journal_title：BJU international

authors： Narayan VM,Gandhi S,Chrouser K,Evaniew N,Dahm P

更新日期：2018-07-01 00:00:00

abstract：:The immediate objective of phosphodiesterase type 5 (PDE5) inhibitor treatment is to restore the ability of a man to achieve and/or maintain an erection adequate for sexual intercourse. As erectile dysfunction (ED) generally develops in the second half of life, the ultimate objective generally is not procreation, but ...

journal_title：BJU international

authors： Mirone V,Fusco F,Rossi A,Sicuteri R,Montorsi F

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:To investigate the associations of host metabolic factors and metabolic syndrome on prostate cancer-specific death (PCSD) and overall survival (OS) in patients treated with androgen deprivation therapy (ADT) for biochemically recurrent disease. PATIENTS AND METHODS:The analysis included 273 patients with pr...

journal_title：BJU international

authors： Rudman SM,Gray KP,Batista JL,Pitt MJ,Giovannucci EL,Harper PG,Loda M,Mucci LA,Sweeney CJ

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To determine whether clinicians discuss bone-specific side-effects with patients on androgen-deprivation therapy (ADT) for prostate cancer, or prescribe lifestyle and pharmacological interventions for low bone mineral density (BMD), as decreased BMD is a common side-effect of ADT, leading to increased risk of...

journal_title：BJU international

authors： Panju AH,Breunis H,Cheung AM,Leach M,Fleshner N,Warde P,Duff-Canning S,Krahn M,Naglie G,Tannock I,Tomlinson G,Alibhai SM

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:To compare targeted, transperineal magnetic resonance imaging (MRI)/ultrasound (US)-fusion biopsy to systematic transrectal biopsy in patients with previous negative or first prostate biopsy and to evaluate the gain in diagnostic information with systematic biopsies in addition to targeted MRI/US-fusion biop...

journal_title：BJU international

authors： Borkowetz A,Platzek I,Toma M,Laniado M,Baretton G,Froehner M,Koch R,Wirth M,Zastrow S

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between the presence of high-grade prostatic intraepithelial neoplasia (HGPIN) in retropubic radical prostatectomy (RP) specimens and cancer-specific outcomes, including pathological variables and biochemical disease-free survival (bDFS), as HGPIN shares many histopathological char...

journal_title：BJU international

authors： Pierorazio PM,Lambert SM,Matsukhani M,Sprenkle PC,McCann TR,Katz AE,Olsson CA,Benson MC,McKiernan JM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:To determine the risk of failure during drug development in castration-resistant prostate cancer (CRPC) and to identify factors that could improve outcomes. METHODS:We investigated CRPC by analysing compounds in phase I to phase III clinical trials between 1998 and April 2011. Drug development failures were...

journal_title：BJU international

authors： Tenuta A,Klotz L,Parker JL

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To assess the use of sodium pentosan polysulphate (SPP) for haemorrhagic cystitis (HC), a potentially life-threatening side-effect in patients treated with pelvic radiotherapy or cyclophosphamide, and which can be difficult to manage as patients often have significant comorbidity. PATIENTS AND METHODS:Betwee...

journal_title：BJU international

authors： Sandhu SS,Goldstraw M,Woodhouse CR

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:To investigate histopathologically the beneficial effects of Panax ginseng extract on guinea pig testes damaged by 2,3, 7,8-tetrachlorodibenzo-p-dioxin (TCDD). MATERIALS AND METHODS:Ninety guinea pigs were divided into six equal groups. The normal controls (group 1) received vehicle and saline; group 2 rece...

journal_title：BJU international

authors： Kim W,Hwang S,Lee H,Song H,Kim S

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To describe the preclinical pharmacology of Ro 115-1240, a peripherally acting selective alpha1A/1L-adrenoceptor (AR) partial agonist, compared with the alpha1A/1L-AR full agonist amidephrine, as AR agonists have some utility in the treatment of stress urinary incontinence (SUI) but are limited by undesirable...

journal_title：BJU international

authors： Blue DR,Daniels DV,Gever JR,Jett MF,O'Yang C,Tang HM,Williams TJ,Ford AP

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To determine whether heat, used in transurethral microwave thermotherapy (TUMT) for benign prostatic hyperplasia and which causes necrotic lesions within the adenoma, induces apoptosis in benign human prostatic stromal cells. Materials and methods Prostatic stromal cells were cultured from benign human prosta...

journal_title：BJU international

authors： Brehmer M,Svensson I

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To determine the neurophysiological and vascular factors in diabetic impotence, particularly the role of autonomic neuropathy on venous leakage and erectile impotence. PATIENTS AND METHODS:Thirty-four diabetic men with impotence were investigated using various neurophysiological and radiological methods. The...

journal_title：BJU international

authors： Colakoglu Z,Kutluay E,Ertekin C,Altay B,Killi R,Alkis A

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:To determine if a decrease in oestrogen (E) levels increases activity in bladder afferent nerves, by investigating the effects of E loss on afferent nerve activity in ovariectomized (OVX) rats, and making comparisons with findings in ageing female rats. MATERIALS AND METHODS:Female Sprague-Dawley rats were d...

journal_title：BJU international

authors： Aizawa N,Iijima K,Rosenbaum JS,Downs TR,Igawa Y,Andersson KE,Wyndaele JJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:To evaluate whether robotically assisted laparoscopic prostatectomy (RALP) is less invasive than radical retropubic prostatectomy (RRP), as experimental studies suggest that the acute phase reaction is proportional to surgery-induced tissue damage. PATIENTS AND METHODS:Between May and November 2006, all pat...

journal_title：BJU international

authors： Fracalanza S,Ficarra V,Cavalleri S,Galfano A,Novara G,Mangano A,Plebani M,Artibani W

更新日期：2008-05-01 00:00:00

abstract：:Jim Peters, a country boy who excelled academically and in the sporting arena was a Victorian urological pioneer. His passion for teaching and belief in the development of Australasian urology resulted in the establishment of two of Melbourne's earliest Urology Units (which are now major academic University department...

journal_title：BJU international

authors： Webb DR

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To compare the outcomes for laparoscopic vascular hitch (VH) and dismembered pyeloplasty in patients with pelvi-ureteric junction obstruction (PUJO) secondary to crossing vessels (CV). PATIENTS AND METHODS:Patients who underwent laparoscopic management of CV at our institution were identified between 2008 an...

journal_title：BJU international

authors： Kim JK,Keefe DT,Rickard M,Milford K,Lorenzo AJ,Chua ME

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:To determine the changes in body composition, muscle function and energy expenditure after radical cystectomy (RC). PATIENTS AND METHODS:Eleven consecutive men (median age 66 years, range 44-79) who had a RC over a 1-year period had measurements made of their total body protein, by neutron-activation analysi...

journal_title：BJU international

authors： Mathur S,Plank LD,Hill AG,Rice MA,Hill GL

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of low-dose rate prostate brachytherapy on the sexual health of men with > or = 7 years of prospective evaluation and optimum sexual function before treatment. PATIENTS AND METHODS:In all, 223 patients with T1b to T3a prostate cancer and a median (range) age of 66 (50-82) years were tr...

journal_title：BJU international

authors： Cesaretti JA,Kao J,Stone NN,Stock RG

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinicopathological outcomes for patients with clinical T2 (cT2) urothelial carcinoma treated with radical cystectomy (RC) without neoadjuvant chemotherapy (NC). PATIENTS AND METHODS:We identified 212 patients with cT2 tumours who underwent RC at our institution without NC. Pathological asses...

journal_title：BJU international

authors： Canter D,Long C,Kutikov A,Plimack E,Saad I,Oblaczynski M,Zhu F,Viterbo R,Chen DY,Uzzo RG,Greenberg RE,Boorjian SA

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:The aim of the present paper was to determine the impact of testicular cancer (TC) and its treatments on fertility and to review the current management options for the infertile patient with TC, both before diagnosis and after treatment, with the aim of providing practical recommendations to update contempor...

journal_title：BJU international

authors： Moody JA,Ahmed K,Yap T,Minhas S,Shabbir M

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To assess the predictive value of serial bone scans as a surveillance tool for bone metastasis in men with clinically localized prostate cancer and managed with watchful observation. PATIENTS AND METHODS:A prospective single-arm study was conducted to assess the feasibility of a watchful observation protocol...

journal_title：BJU international

authors： Yap BK,Choo R,Deboer G,Klotz L,Danjoux C,Morton G

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To identify predictors of delayed therapy with curative intent, an increasingly common option in contemporary patients with prostate cancer who initially choose watchful waiting. PATIENTS AND METHODS:The characteristics of all patients at one institution and diagnosed with T1-4NXM0 prostate cancer between 19...

journal_title：BJU international

authors： el-Geneidy M,Garzotto M,Panagiotou I,Hsieh YC,Mori M,Peters L,Klein T,Beer TM

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:• To report outcomes for patients with localized prostate cancer managed using a watchful waiting strategy at an American centre and to explore factors that have triggered intervention. PATIENTS AND METHODS:• From 1991 to 2005, 218 patients diagnosed with untreated localized prostate cancer were followed at ...

journal_title：BJU international

authors： Coen JJ,Feldman AS,Smith MR,Zietman AL

更新日期：2011-05-01 00:00:00

abstract：:Accurate prediction is essential for patient counselling, appropriate selection of treatments and determination of eligibility for clinical trials. In this review we assess the available determinants of oncological outcome after radical cystectomy (RC) for transitional cell carcinoma of the urinary bladder. We reviewe...

journal_title：BJU international

authors： Margulis V,Lotan Y,Montorsi F,Shariat SF

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To critically review published data on the urogynaecological aspects of female sexual dysfunction (FSD), as FSD is a developing multidisciplinary issue associated with several biological, medical and psychological factors. METHODS:The reported prevalence of FSD is 19-50% and women with lower urinary tract sy...

journal_title：BJU international

authors： Dalpiaz O,Kerschbaumer A,Mitterberger M,Pinggera GM,Colleselli D,Bartsch G,Strasser H

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:• To evaluate the functional and morphological outcome after open pyeloplasty for ureteropelvic junction obstruction (UPJO) with huge renal pelvis. PATIENTS AND METHODS:• A retrospective review of all cases who underwent pyeloplasty for huge renal pelvis was conducted. • Records were evaluated with respect t...

journal_title：BJU international

authors： Sarhan O,Helmy T,Abou-El Ghar M,Baky MA,El-Assmy A,Dawaba M

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To present our initial experience in children undergoing single-port laparoscopic varicocelectomy (SPLV) using a new approach in which the entire procedure is performed through a multichannel single laparoscopic port inserted in the umbilicus rather than the traditional LV performed through three abdominal po...

journal_title：BJU international

authors： Kaouk JH,Palmer JS

更新日期：2008-07-01 00:00:00

abstract：:Category III chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most commonly diagnosed prostatitis syndrome. CP/CPPS is characterized by lower urinary tract symptoms (LUTS) of which pain (particularly perineal pain and pain on ejaculation) and dysfunctional voiding cause the greatest morbidity and poor...

journal_title：BJU international

authors： Nickel JC

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To assess the early disclosure and treatment of meatal stenosis after hypospadias repair, using calibration of the neourethral meatus at regular intervals to detect stenosis, and to assess the curative effects of dilatation with topical corticosteroids. PATIENTS AND METHODS:Between 2001 and 2003, 83 boys (me...

journal_title：BJU international

authors： Radojicic ZI,Perovic SV,Stojanoski KD

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness and safety of standard percutaneous nephrolithotomy (sPCNL) and super-mini PCNL (SMP). PATIENTS AND METHODS:A total of 150 patients presenting with renal calculi of <2 cm were randomised to either sPCNL (Group 1) or SMP (Group 2). Randomisation was based on centralised computer-g...

journal_title：BJU international

authors： Guddeti RS,Hegde P,Chawla A,de la Rosette JJMCH,Laguna Pes MP,Kapadia A

更新日期：2020-08-01 00:00:00