Abstract:
OBJECTIVE:To evaluate extended lymph node dissection (LND) as a nodal staging tool in the treatment of invasive carcinoma of the urinary bladder and to suggest a reasonable proximal limit of the dissection. PATIENTS AND METHODS:In all, 170 patients underwent radical cystectomy with extended LND up to the level of the inferior mesenteric artery. Specimens were evaluated as 13 separate packages from pre-designated anatomical locations. The number of LNs and presence of positive LNs (LN+) at each location was prospectively registered. RESULTS:The median (range) number of LNs removed was 24 (6-62). In all, 25.3% of the patients had LN+. The median (range) number of LN+ was 2 (1-20). Advanced T-stage was correlated with a higher risk of LN+ but not to the specific location of the LN+. Two patients had LN+ above the common iliac bifurcation with no LN+ more distally located within the pelvic region. All other patients with LN+ above the common iliac bifurcation had more distally located LN+. There were no skip lesions to LNs above the aortic bifurcation. CONCLUSIONS:Extended LND above the common iliac bifurcation including the presacral area provides a more accurate LN staging compared with a standard pelvic LND. Extending the limits above the aortic bifurcation is not necessary from a staging perspective.
journal_name
BJU Intjournal_title
BJU internationalauthors
Jensen JB,Ulhøi BP,Jensen KMdoi
10.1111/j.1464-410X.2009.09118.xsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
199-205issue
2eissn
1464-4096issn
1464-410Xpii
BJU9118journal_volume
106pub_type
杂志文章abstract:OBJECTIVE:To investigate the effects of sildenafil on noradrenaline- and potassium-induced contractions of isolated human seminal vesicles (SVs), as premature ejaculation is a relatively common male sexual dysfunction that currently lacks an adequate therapy, and recent in vitro tests showed that sildenafil induces rel...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07260.x
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of weight loss and time post laparoscopic gastric banding surgery (LGB) on urinary and sexual function. MATERIALS AND METHODS:653 females and 145 males who underwent LGB over the last 10 years at a single centre in Australia were contacted by post and asked to complete validated qu...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09509.x
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder. PATIENTS AND METHODS:The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was f...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06541.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:To compare the effects of taking tadalafil 5 mg and placebo once daily on post-micturition dribble (PMD) in men with lower urinary tract symptoms (LUTS). PATIENTS AND METHODS:Our prospective, randomized, double-blind, placebo-controlled, multicentre trial enrolled 102 men with PMD and other LUTS. PMD was as...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.14849
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of detrusor instability (DI) detected by conventional and ambulatory bladder pressure monitoring, any link between urodynamic findings before and after colposuspension, and between patients' symptoms and the urodynamic findings. PATIENTS AND METHODS:Sixty-five patients, scheduled t...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00390.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To present our initial experience in children undergoing single-port laparoscopic varicocelectomy (SPLV) using a new approach in which the entire procedure is performed through a multichannel single laparoscopic port inserted in the umbilicus rather than the traditional LV performed through three abdominal po...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07584.x
更新日期:2008-07-01 00:00:00
abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: For patients who are unfit for extirpative surgery, percutaneous cryoablation (PCA) presents a minimally-invasive alternative for the treatment of renal masses. PCA has been demonstrated to be safe, with complication rates <10% being reported consist...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11432.x
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the tissue yield of a new core-biopsy needle with an end-cut mechanism when used for transrectal prostate biopsies. PATIENTS AND METHODS:The end-cut instrument has an adjustable stroke length (13, 23 or 33 mm) and an inner and an outer cannula, but no trocar. It was compared with the conventional...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02809.x
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVE:To explore the safety and clinical efficacy of continuous-wave laser vaporesection for the treatment of obstructive benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:We treated 72 consecutive patients with obstructive BPH using a 70 W 2-microm continuous-wave laser. The mean (range) age of the patient...
journal_title:BJU international
pub_type: 临床试验,杂志文章
doi:10.1111/j.1464-410X.2008.08040.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To compare the cost-effectiveness of surgery and topical steroids as treatments for phimosis (defined as a clinically verifiable, pathological, cicatricial stenosis of the prepuce) and to evaluate the financial basis of these treatments. METHODS:Data on treatment using topical steroids was obtained from publ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1046/j.1464-410x.2001.02033.x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVES:To determine the incidence of severe pain after ureteric stent removal. To evaluate the efficacy of a single dose of a non-steroidal anti-inflammatory drug (NSAID) in preventing this complication. PATIENTS AND METHODS:A prospective, randomised, double-blind, placebo-controlled trial was performed at our ins...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2012.11214.x
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To determine the endocrine effects, efficacy and tolerability of a 10.8-mg depot formulation of Zoladextrade mark (goserelin acetate, Zeneca Pharmaceuticals, Wilmington, Delaware, USA), a luteinizing hormone-releasing hormone agonist analogue, when administration was extended from every 12 weeks to every 13 w...
journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1046/j.1464-410x.1999.00028.x
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To investigate the potential utility of a new combined immunostaining technique for diagnosing prostate cancer from histological analysis of needle biopsy specimens. MATERIALS AND METHODS:Tissue was immunostained with a combination of antibodies against a basal cell marker (p63), and an enzyme commonly overe...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06069.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To quantify the incremental detection rate (DR) of a targeted biopsy in addition to a randomized 10-core biopsy. PATIENTS AND METHODS:This retrospective study analysed 1024 patients who consecutively underwent a four-core real-time elastography (RTE) targeted biopsies in addition to a randomized 10-core tran...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12517
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To investigate the matrix metalloproteinases (MMPs) 2 and 9 in bladder cancer cell lines stimulated with epidermal growth factor (EGF), and to investigate the presence of gelatinases in the urine of patients with bladder tumours, in relation to the stage and grade of tumour and the EGF receptor (EGFR) status...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04020.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the clinical significance of preoperative erythrocyte sedimentation rate (ESR) and neutrophil-lymphocyte ratio (NLR) as prognostic factors in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma (UTUC). PATIENTS AND METHODS:A total of 410 patients were retrospectiv...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12846
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the cost-effectiveness of degarelix vs luteinizing hormone-releasing hormone analogue (triptorelin) plus short-term antiandrogen treatment for advanced prostate cancer. METHODS:We developed a decision analytic model based on a clinical trial and literature review. The two interventions evaluated ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10434.x
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To conduct a meta-analysis of the literature on the peri-operative outcomes of both robot-assisted partial nephrectomy (RAPN) and laparoscopic partial nephrectomy (LPN). MATERIALS AND METHODS:An electronic database search of MEDLINE, EMBASE, Google Scholar and the Cochrane Library was performed for publicati...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/bju.12255
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To determine if patients who undergo tubularized incised-plate (TIP) urethroplasty need regular dilatation to prevent neourethral strictures or meatal stenosis. PATIENTS AND METHODS:The follow-up of two consecutive series of patients who underwent primary TIP hypospadias repair by one surgeon was reviewed. T...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.01901.x
更新日期:2002-01-01 00:00:00
abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The various phenotypes of hypospadias may result from disturbances of dissimilar embryonic processes in different time windows, suggesting aetiological heterogeneity; however, only a few studies have investigated the risk factors for the different hy...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11745.x
更新日期:2013-07-01 00:00:00
abstract::Three-dimensional (3D) printing or additive manufacturing is a new technology that has seen rapid development in recent years with decreasing costs. 3D printing allows the creation of customised, finely detailed constructs. Technological improvements, increased printer availability, decreasing costs, improved cell cul...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/bju.14928
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of long-term clomiphene citrate (CC) therapy in symptomatic patients with hypogonadism (HG). PATIENTS AND METHODS:Serum T, oestradiol and luteinizing hormone (LH) were measured in patients who were treated with CC for over 12 months. Additionally, bone densitometry (BD) resu...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.10968.x
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To characterise the clinical, radiological and histological features of mucinous tubular and spindle cell carcinoma (MTSCC), as well as oncological outcomes. PATIENTS AND METHODS:This is a single institution retrospective analysis of all patients with MTSCC from 2002 to 2011. Patients were excluded if MTSCC ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12992
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:To help clarify which small renal cortical neoplasms (RCNs) require surgery by using office-based, ultrasonography-guided percutaneous renal biopsy. PATIENTS AND METHODS:Biopsies were performed using facilitated ultrasound targeting (FUT) technology, which incorporates a needle guide and onscreen beam-steer...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12489
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To examine a large, single-surgeon series of patients with prostate cancer who underwent retropubic radical prostatectomy (RRP) for men with postoperative bladder neck contractures (BNCs). PATIENTS AND METHODS:From 1983 to 2007, 4132 men underwent RRP for prostate cancer by one surgeon. All patients had BN r...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08700.x
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:To study the patterns of care of penile cancer diagnosed in the state of New South Wales (NSW) over a 10 year period and determine factors that are associated with differences in survival. PATIENTS AND METHODS:All invasive penile cancer diagnosed between 2001 and 2009 in NSW, Australia, were identified from...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13626
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that bladder cancer is a heterogeneous disease. PATIENTS AND METHODS:We examined the temporal trends of bladder cancer by histological subtype and by disease stage and grade using the National Cancer Institute's Surveillance, Epidemiology, and End Results data collected in 1973-2007. ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10283.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To investigate the potential role of platelet-derived growth factor-AA (PDGF-AA) and the PDGF-α receptor as prognostic markers in Wilms' tumour. PATIENTS AND METHODS:The expression of PDGF-AA and PDGF-α were investigated using immunohistochemical analysis of 62 Wilms' tumours. Patients were treated with chem...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09211.x
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury. MATERIALS AND METHODS:Given the great similarity between the anatomical structure of the cavernous nerve in rats and humans, 24 rats underwent dissections and the cavernous nerves were identified with the aid of an operating mi...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07760.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of demographic, clinical, treatment and patient-reported parameters on satisfaction with prostate cancer care. Despite the significant worldwide impact of prostate cancer, few data are available specifically addressing satisfaction with treatment-related care. PATIENTS AND METHODS:CaPS...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11423.x
更新日期:2013-02-01 00:00:00