Abstract:
:Erectile dysfunction is common in the ageing man and reliable therapies are needed. The pathophysiology of erectile dysfunction in this group mainly includes chronic ischaemia, which triggers the deterioration of cavernosal smooth muscle and the development of corporeal fibrosis. Assessing the ageing man with erectile dysfunction who seeks medical treatment should comprise a thorough medical and sexual history, a systemic and focused physical examination and selected blood tests. Oral drug therapy represents a safe and effective option for most ageing men.
journal_name
BJU Intjournal_title
BJU internationalauthors
Montorsi F,Briganti A,Salonia A,Deho' F,Zanni G,Cestari A,Guazzoni G,Rigatti P,Stief Cdoi
10.1046/j.1464-410x.2003.04378.xkeywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
516-20issue
5eissn
1464-4096issn
1464-410Xpii
4378journal_volume
92pub_type
杂志文章,评审abstract:OBJECTIVES:To retrospectively review hypogonadal men receiving testosterone replacement therapy (TRT), and evaluate the changes in prostate-specific antigen (PSA) levels over an extended period, and thus evaluate the occurrence of prostate cancer, as a primary concern in treating late-onset hypogonadism (LOH) is the po...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08240.x
更新日期:2009-05-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? Renal forniceal rupture is a common finding in patients with ureteral obstruction. It is thought to be due to increased renal pelvis pressure from backup of urine, causing one or more renal fornices to leak urine. This phenomenon has not been systemat...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10164.x
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of 50 mg mirabegron once daily for ureteric stent-related discomfort after ureteroscopic procedures by conducting a multicentre randomized study. PATIENTS AND METHODS:A total of 100 patients with indwelling ureteric stents after ureteroscopic stone removal or retrograde intrarenal su...
journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.14416
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:• To evaluate the effect of transurethral resection of the prostate (TURP) on sexual function in the short (6 months), medium (6 years) and long (12 years) term and assess the conformity between patient and partner regarding sexual function. PATIENTS AND METHODS:• A prospective cohort study set at the Aberde...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10396.x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:•To determine the optimal treatment for incidentally detected small renal masses between radical nephrectomy, partial nephrectomy, ablative therapy (AT) and active surveillance (AS) using a decision-analytic Markov model. SUBJECTS AND METHODS:•The reference case was an otherwise healthy 60-year-old patient. ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10115.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To determine the metabolic characteristics of elderly patients with recurrent calcium oxalate stones. PATIENTS AND METHODS:Metabolic abnormalities were investigated in 88 patients with recurrent calcium oxalate stones, including 70 aged <60 years and 18 aged >/=60 years. The frequency of each metabolic abnor...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00057.x
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To describe metastasis-free survival (MFS) in men with prostate-specific antigen (PSA) recurrence following radical prostatectomy, and to define clinical prognostic factors modifying metastatic risk. PATIENTS AND METHODS:We conducted a retrospective analysis of 450 men treated with prostatectomy at a tertiar...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10422.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To illustrate the ultrastructural fibre composition of the rat cavernosal nerve at serial levels, from its origin in the main pelvic ganglion to its termination in the corpus cavernosum of the distal penile shaft, and to develop a technique that permits repeated electrophysiological recording from the fibres ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06726.x
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:To re-evaluate the role of diabetes mellitus (DM) as a risk factor for penile implant infection by exploring the association between glycated haemoglobin (HbA1c) levels and penile implant infection rates and to define a threshold value that predicts implant infection. PATIENTS AND METHODS:We conducted a mul...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.14076
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between renal tumour complexity and outcomes in a large cohort of patients undergoing percutaneous cryoablation (PCA). PATIENTS AND METHODS:Patients with renal tumours treated with PCA were identified using our prospectively maintained ablation registry (2003-2015). Salvage proced...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13841
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To describe the preclinical pharmacology of Ro 115-1240, a peripherally acting selective alpha1A/1L-adrenoceptor (AR) partial agonist, compared with the alpha1A/1L-AR full agonist amidephrine, as AR agonists have some utility in the treatment of stress urinary incontinence (SUI) but are limited by undesirable...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410x.2004.04577.x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To investigate the prognostic value of the Gleason score in prostate cancer. PATIENTS AND METHODS:A consecutive series of 305 men with prostate cancer diagnosed at transurethral resection (1975-1990) and with no curative treatment was analysed. There was no assessment of prostate-specific antigen level durin...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02669.x
更新日期:2002-04-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (case series). LEVEL OF EVIDENCE:4. What's known on the subject? and What does the study add? The indications and timing of native nephrectomy in patients with autosomal dominant polycystic kidney disease (ADPKD) is controversial, especially for those undergoing renal transplantation. P...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09938.x
更新日期:2011-08-01 00:00:00
abstract::To analyse studies validating the effectiveness of robotic surgery simulators. The MEDLINE(®), EMBASE(®) and PsycINFO(®) databases were systematically searched until September 2011. References from retrieved articles were reviewed to broaden the search. The simulator name, training tasks, participant level, training d...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11270.x
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the early results of hand-assisted radical nephrectomy and nephroureterectomy in our institution. PATIENTS AND METHODS:The records of 13 patients with malignant disease of the kidney who underwent hand-assisted laparoscopic radical nephrectomy and nephroureterectomy were reviewed retrospectively....
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02955.x
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To devise a procedure capable of curing complicated ureteric strictures and replacing segments of lost ureter, without the long-term infective complications of bowel interposition or the surgical magnitude of autotransplantation. PATIENTS AND METHODS:Four patients with complicated strictures and one with seg...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00019.x
更新日期:1999-05-01 00:00:00
abstract::Tribute to Professor Pieter De Mulder, from Martin Gore. Pieter and I were often pitted against each other in debates at international meetings on the role of cytokine therapy. The truth is that there was little disagreement between us, but we both thought such set pieces were a good way to highlight the issues surrou...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2008.07435.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the sensitivity and specificity of urinary nuclear matrix protein-22 (NMP22) in detecting bladder cancer, to compare the diagnostic performance of NMP22 alone and when corrected by urinary creatinine level, and to correlate NMP22 level with the histological and clinical characteristics of bladder...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00254.x
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVES:To determine the clinical utility of blood tests as a screening tool for metabolic abnormalities in patients with kidney stone disease. SUBJECTS AND METHODS:Clinical and biochemical data from 709 patients attending the Oxford University Hospitals NHS Foundation Trust for assessment and treatment of kidney s...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15250
更新日期:2020-09-23 00:00:00
abstract:OBJECTIVES:To determine the most frequent urodynamic observations associated with bladder calculi, and to assess whether the presence of calculi alters these observations. PATIENTS AND METHODS:Fifty patients with bladder stones were included in a prospective study in which two urodynamic tests were used, one at inclus...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.04815.x
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To determine, using a postal questionnaire survey of practising British consultant urologists, the duration and type of antibiotic deemed most effective in patients with an existing indwelling catheter before transurethral resection of the prostate (TURP), as the value of prophylactic antibiotics before TURP ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04429.x
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To assess the potential of p21 as a gene therapy treatment for prostate cancer, by introducing p21 into both androgen-dependent (AD) and -independent (AI) human prostate cancer cell lines via a recombinant adenoviral vector, Ad5CMV-p21, carrying human p21 cDNA. MATERIALS AND METHODS:The LNCaP, DU145 and PC-3...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04318.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:To compare targeted, transperineal magnetic resonance imaging (MRI)/ultrasound (US)-fusion biopsy to systematic transrectal biopsy in patients with previous negative or first prostate biopsy and to evaluate the gain in diagnostic information with systematic biopsies in addition to targeted MRI/US-fusion biop...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13023
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:To determine the neurophysiological and vascular factors in diabetic impotence, particularly the role of autonomic neuropathy on venous leakage and erectile impotence. PATIENTS AND METHODS:Thirty-four diabetic men with impotence were investigated using various neurophysiological and radiological methods. The...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00916.x
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between glycogen content in bladder detrusor tissue and historical bladder function in a guinea-pig model of partial bladder outlet obstruction (PBOO). MATERIALS AND METHODS:In male immature guinea pigs PBOO was created with a silver ring around the proximal urethra; a control grou...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07046.x
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:• To investigate the feasibility of tissue-engineered corpus cavernosum (TECC) with muscle-derived stem cells (MDSCs) as seed cells and determine the growth potential in vivo. MATERIALS AND METHODS:• Acellular corporal collagen matrices (ACCMs) were obtained from adult rabbit penis by a cell removal procedur...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09695.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To investigate the high circumcision rate in South Korea and its rapid increase in the short period since its introduction. SUBJECTS AND METHODS:From January to December 2000, 5434 South Korean males (or their parents) aged 0-92 years were interviewed in detail about their circumcision status, their age at c...
journal_title:BJU international
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Data from the Japanese Urological Society showed that, in Japan, almost half of patients with localized prostate cancer are treated with hormone therapy (HT), regardless of disease stage, and that radiation therapy (RT) is also widely used to treat high-risk patients. A retrospective study was undertaken in Japan to e...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2007.06592.x
更新日期:2007-01-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? In the 1980s and 1990s, a method for direct measurement of pressure and cross-sectional area in women and men was developed. It was successful in terms of obtaining meaningful results in several studies. But the technique, which was based on the field...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.10997.x
更新日期:2012-10-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? For the past 30 years Serenoa repens has become a widely used phytotherapy in the USA and in Europe, mostly because of positive comparisons to α-blockers and 5α-reductase inhibitors. During the last 4 years we have seen two very high quality trials co...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11172.x
更新日期:2012-06-01 00:00:00