Telomerase activity in disseminated prostate cancer cells.

abstract：OBJECTIVES:To investigate the receptors for angiotensin II (AII, reported to be a potent contractile agent in human urinary bladder), using functional and autoradiographic techniques in child and adult bladder specimens. Materials and methods Bladder specimens were obtained from 61 children (aged 4 months to 12 years) ...

journal_title：BJU international

authors： Lam DS,Dias LS,Moore KH,Burcher E

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To describe the preclinical pharmacology of Ro 115-1240, a peripherally acting selective alpha1A/1L-adrenoceptor (AR) partial agonist, compared with the alpha1A/1L-AR full agonist amidephrine, as AR agonists have some utility in the treatment of stress urinary incontinence (SUI) but are limited by undesirable...

journal_title：BJU international

authors： Blue DR,Daniels DV,Gever JR,Jett MF,O'Yang C,Tang HM,Williams TJ,Ford AP

更新日期：2004-01-01 00:00:00

abstract：:The introduction of prostate-specific antigen (PSA) has revolutionized the detection and management of patients with prostate cancer. Despite this there has always been a concern among clinicians about the usefulness of total PSA levels as a marker for prostate cancer. We discuss the use of calculated variables and mo...

journal_title：BJU international

authors： Shariat SF,Karam JA,Margulis V,Karakiewicz PI

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To compare extracorporeal shockwave lithotripsy (ESWL) and ureteroscopy (URS) as first-line treatments for patients with distal ureteric stones. PATIENTS AND METHODS:In all, 273 patients with single, monolateral, radiopaque, distal ureteric stones of 0.5-1.5 cm were enrolled in a prospective randomized trial...

journal_title：BJU international

authors： Verze P,Imbimbo C,Cancelmo G,Creta M,Palmieri A,Mangiapia F,Buonopane R,Mirone V

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To document the clinicopathological features of prostate cancer in a cohort of Jamaican men, and to determine which of these features are of prognostic significance in this population. PATIENTS AND METHODS:The clinical and pathological findings in 99 patients with prostate cancer (diagnosed consecutively aft...

journal_title：BJU international

authors： Shirley SE,Escoffery CT,Sargeant LA,Tulloch T

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To investigate the associations of a range of personal and clinical variables with bladder cancer survival in men and women in NSW to see if we could explain why bladder cancer survival is consistently poorer in women than in men. PATIENTS AND METHODS:All 6880 cases of bladder cancers diagnosed in NSW betwee...

journal_title：BJU international

authors： Tracey E,Watt H,Currow D,Young J,Armstrong B

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of vardenafil in patients previously unresponsive to sildenafil. PATIENTS AND METHODS:A multicentre, double-blind, 12-week, flexible-dose, placebo-controlled trial was conducted, involving 463 men aged > or = 18 years with moderate-to-severe erectile dysfunction (ED) and who were unr...

journal_title：BJU international

authors： Carson CC,Hatzichristou DG,Carrier S,Lording D,Lyngdorf P,Aliotta P,Auerbach S,Murdock M,Wilkins HJ,McBride TA,Colopy MW,Patient Response with Vardenafil in Slidenafil Non-Responders (PROVEN) Study Group.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence, type and treatment behaviour of women with urinary incontinence in four European countries. SUBJECTS AND METHODS:Data were collected using a postal survey which was sent to 29,500 community-dwelling women aged > or = 18 years in France, Germany, Spain and the UK. Subjects were as...

journal_title：BJU international

authors： Hunskaar S,Lose G,Sykes D,Voss S

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To review our experience in the management of secondary pelvi-ureteric junction obstruction (PUJO) comparing endopyelotomy with pyeloplasty. PATIENTS AND METHODS:We retrospectively analysed our database of 58 patients having undergone operative management of PUJO after failed primary management, including 41...

journal_title：BJU international

authors： Vannahme M,Mathur S,Davenport K,Timoney AG,Keeley FX Jr

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the distribution of c-kit-positive interstitial cells of Cajal (ICCs) in normal bladder and bladders from patients with megacystis-microcolon-intestinal peristalsis syndrome (MMIHS, a rare congenital and generally fatal cause of functional intestinal obstruction in the newborn), the most charac...

journal_title：BJU international

authors： Piaseczna Piotrowska A,Rolle U,Solari V,Puri P

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of chronic and debilitating symptoms of the overactive bladder, defined here as the presence of chronic frequency, urgency and urge incontinence (either alone or in any combination), and presumed to be caused by involuntary detrusor contractions. Subjects and methods Data were coll...

journal_title：BJU international

authors： Milsom I,Abrams P,Cardozo L,Roberts RG,Thüroff J,Wein AJ

更新日期：2001-06-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? In the 1980s and 1990s, a method for direct measurement of pressure and cross-sectional area in women and men was developed. It was successful in terms of obtaining meaningful results in several studies. But the technique, which was based on the field...

journal_title：BJU international

authors： Aagaard M,Klarskov N,Sønksen J,Bagi P,Colstrup H,Lose G

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of OnabotulinumtoxinA (BTXA) injections in men with drug-refractory non-neurogenic overactive bladder (NNOAB). PATIENTS AND METHODS:A total of 43 men received BTXA injections for NNOAB from 2004 to 2012. Patient Global Impression of Improvement (PGI-I) score was obtained. For men with ...

journal_title：BJU international

authors： Habashy D,Losco G,Tse V,Collins R,Chan L

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To present the template-guided transperineal prostate biopsy (TPB) outcomes for patients of two urologists from a single institution. PATIENTS AND METHODS:We conducted a prospective study of 409 consecutive men who underwent TPB between December 2006 and June 2008 in a tertiary referral centre using a standa...

journal_title：BJU international

authors： Symons JL,Huo A,Yuen CL,Haynes AM,Matthews J,Sutherland RL,Brenner P,Stricker PD

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To characterize the clinicopathological findings and the outcome of human immunodeficiency virus (HIV)-infected patients diagnosed and treated for prostate carcinoma, as HIV-positive men being treated with highly active antiretroviral therapy (HAART) are living longer and thus are more likely to develop cance...

journal_title：BJU international

authors： Pantanowitz L,Bohac G,Cooley TP,Aboulafia D,Dezube BJ

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To summarize the urological procedures recorded in Hospital Episodes Statistics (HES, 1998-99) and to examine the accuracy of coding and HES. MATERIALS AND METHODS:Data on the 10 commonest urological procedures from the Department of Health website (www.doh.gov.uk/hes) were extracted, summarized and presente...

journal_title：BJU international

authors： Lee F,Patel HR,Emberton M

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of erectile dysfunction (ED) in a large cohort of Brazilian men who were screened for prostate cancer, and to determine risk factors in this population, as there are large cultural differences among countries in reporting the frequency of ED, and it is likely that the prevalence of...

journal_title：BJU international

authors： Paranhos M,Antunes A,Andrade E,Freire G,Srougi M

更新日期：2009-10-01 00:00:00

abstract：:Accurate prediction is essential for patient counselling, appropriate selection of treatments and determination of eligibility for clinical trials. In this review we assess the available determinants of oncological outcome after radical cystectomy (RC) for transitional cell carcinoma of the urinary bladder. We reviewe...

journal_title：BJU international

authors： Margulis V,Lotan Y,Montorsi F,Shariat SF

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women. PATIENTS AND METHODS:After a 1-week, placebo lead-in phase, 232 treatment-seeking women with regular menstrual cycles were randomly assigned to bupropion SR 150 mg/d...

journal_title：BJU international

authors： Safarinejad MR,Hosseini SY,Asgari MA,Dadkhah F,Taghva A

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To investigate the utility of a new 'modified-prone' position for treating pre-vesical stones with extracorporeal shock wave lithotripsy (ESWL), usually considered an acceptable and effective treatment for such stones, but for which many different body positions have been used in an attempt to increase its ef...

journal_title：BJU international

authors： Köse AC,Demirbas M

更新日期：2004-02-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (outcomes) Level of Evidence 2a. What's known on the subject? and What does the study add? Erectile dysfunction (ED) is a well known implication of radical prostatectomy (RP). Despite the search for technical improvement in the surgical procedure (e.g. nerve-sparing surgery, robot-assiste...

journal_title：BJU international

authors： Polito M,d'Anzeo G,Conti A,Muzzonigro G

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To isolate new cDNAs corresponding to genes whose expression is increased during castration-induced rat prostate apoptosis. MATERIALS AND METHODS:Differential display of mRNAs from 3-day castrated and normal rat ventral prostates was used to identify differentially expressed clones. Northern blots were hybri...

journal_title：BJU international

authors： Bruyninx M,Ammar H,Reiter E,Cornet A,Closset J

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To examine the effect of age on the biochemical and functional properties, and regional distribution of endothelin (ET) receptors in the rabbit renal pelvis. MATERIALS AND METHODS:The properties of ET receptors in 6-week-old and 6-month-old male rabbit renal pelves were examined using isolated muscle-bath an...

journal_title：BJU international

authors： Wada Y,Latifpour J,Saito M,Afiatpour P,Weiss RM

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To determine if the adjunctive use of power Doppler imaging (PDI) could provide prognostic utility in the treatment of prostate cancer, as an accurate prediction of the clinical behaviour of prostate cancer is important to determine appropriate treatment. PATIENTS AND METHODS:Most centres rely on a digital r...

journal_title：BJU international

authors： Eisenberg ML,Cowan JE,Carroll PR,Shinohara K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To explore the possibility that allogeneic responses might, by chance, encompass cross-reactive T cell clones specific for neo-antigenic tumour determinants, and thereby activate antitumour immunity; such cross-reactions are well documented for antiviral immunity, and genetic instability in developing cancers...

journal_title：BJU international

authors： Muir G,Rajbabu K,Callen C,Fabre JW

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To evaluate whether injection with pericapsular lignocaine before transrectal ultrasonography (TRUS)-guided biopsy reduces the perceived pain of prostatic biopsy. PATIENTS AND METHODS:The study included 121 patients referred for TRUS-guided biopsy of the prostate; 27 underwent biopsy with no previous injecti...

journal_title：BJU international

authors： Walker AE,Schelvan C,Rockall AG,Rickards D,Kellett MJ

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To study the effect of smoking on bladder cancer presentation and outcome in a large cystectomy population. PATIENTS AND METHODS:A database including 546 patients from the University Health Network (Toronto, Canada) and Turku University Hospital (Turku, Finland) was studied. In addition to the association of...

journal_title：BJU international

authors： Boström PJ,Alkhateeb S,Trottier G,Athanasopoulos PZ,Mirtti T,Kortekangas H,Laato M,van Rhijn B,van der Kwast T,Fleshner NE,Jewett MA,Finelli A,Zlotta AR

更新日期：2012-01-01 00:00:00

abstract：:• Renal angiomyolipomas (AMLs) are usually easy to diagnose with imaging alone. They have unique characteristics on ultrasonography, computerised tomography and magnetic resonance imaging that usually allow AMLs to be differentiated from other renal masses. • If this is not possible on imaging criteria then biopsy can...

journal_title：BJU international

authors： Lienert AR,Nicol D

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To examine whether a history of sexually transmitted infections (STIs) or positive STI serology is associated with prevalent and incident benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)-related outcomes in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. METHODS:Self-...

journal_title：BJU international

authors： Breyer BN,Huang WY,Rabkin CS,Alderete JF,Pakpahan R,Beason TS,Kenfield SA,Mabie J,Ragard L,Wolin KY,Grubb RL 3rd,Andriole GL,Sutcliffe S

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To determine if antibiotic prophylaxis is required for intradetrusor botulinum toxin A (BoNT-A) injections. PATIENTS AND METHODS:This was a prospective non-randomized study. Inclusion criteria were adult patients with neurogenic detrusor overactivity who failed anticholinergic-based first-line treatment and ...

journal_title：BJU international

authors： Mouttalib S,Khan S,Castel-Lacanal E,Guillotreau J,De Boissezon X,Malavaud B,Marque P,Rischmann P,Gamé X

更新日期：2010-12-01 00:00:00