Abstract：
OBJECTIVE:To report the use of a novel donor source as a further option to increase the number of patients who might be able to receive a renal transplant. PATIENTS AND METHODS:Between May 1996 and July 2007, 43 kidneys were transplanted using kidneys obtained from patients with small (<3 cm diameter) incidentally detected tumours. After bench surgery to excise the tumour, they were all successfully transplanted into patients who were elderly or had significant comorbidities. RESULTS:Apart from four patients who died from unrelated illnesses, all grafts continued to function with a median and mean follow-up of 25 and 32 months. The follow-up, which included 3-monthly renal ultrasonography and chest X-rays, showed only one case of tumour recurrence, which occurred 9 years after transplantation; the patient remains stable under observation after 18 months. CONCLUSIONS:From our experience we consider that where nephrectomy is used for small, localized, incidentally detected renal tumours, the kidney should be considered for transplantation into carefully selected patients. Such patients with numerous medical comorbidities might benefit from renal transplantation, but not survive the waiting period if they are dependent on a deceased donor graft. Paradoxically the use of these marginal kidneys has the potential to increase the quality and length of life of these patients, despite the apparent contradiction of an intuitive principle of organ transplantation and immunosuppression.
journal_name
BJU Intjournal_title
BJU internationalauthors
Nicol DL,Preston JM,Wall DR,Griffin AD,Campbell SB,Isbel NM,Hawley CM,Johnson DWdoi
10.1111/j.1464-410X.2008.07562.xsubject
Has Abstractpub_date
2008-07-01 00:00:00pages
188-92; discussion 192-3issue
2eissn
1464-4096issn
1464-410Xpii
BJU7562journal_volume
102pub_type
杂志文章abstract：UNLABELLED:What's known on the subject? and What does the study add? In the 1980s and 1990s, a method for direct measurement of pressure and cross-sectional area in women and men was developed. It was successful in terms of obtaining meaningful results in several studies. But the technique, which was based on the field...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2012.10997.x
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:To prospectively investigate the association of endothelial nitric oxide synthase (eNOS) G894T gene polymorphism with responsiveness to a selective α1 -blocker in men with benign prostatic hyperplasia related lower urinary tract symptoms (BPH/LUTS), as nitric oxide has recently gained increasing recognition a...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.13468
更新日期：2016-08-01 00:00:00
abstract：:The development of new imaging techniques and the refinement of established methods in uroradiological imaging is proceeding rapidly. In the last few years several important developments have been implemented in the routine diagnostic evaluation of urological patients.A milestone is the recent advent of multidetector ...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1046/j.1464-410x.2002.02620.x
更新日期：2002-03-01 00:00:00
abstract：:Jim Peters, a country boy who excelled academically and in the sporting arena was a Victorian urological pioneer. His passion for teaching and belief in the development of Australasian urology resulted in the establishment of two of Melbourne's earliest Urology Units (which are now major academic University department...
journal_title：BJU international
pub_type： 传,历史文章,杂志文章
doi：10.1111/bju.12377
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVES:To evaluate the sensitivity and specificity of urinary nuclear matrix protein-22 (NMP22) in detecting bladder cancer, to compare the diagnostic performance of NMP22 alone and when corrected by urinary creatinine level, and to correlate NMP22 level with the histological and clinical characteristics of bladder...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00254.x
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:• To systematically review the literature on gemcitabine chemotherapy for advanced or metastatic bladder cancer. MATERIALS AND METHODS:• The Medical Literature Analysis and Retrieval System Onlinedatabase (MEDLINE), the Excerpta Medicadatabase (EMBASE), the Cumulative Index to Nursing and Allied Health Liter...
journal_title：BJU international
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1464-410X.2011.10341.x
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether ageing and diabetes alter the expression of the gap junction protein connexin43 (Cx43) and of particular purinoceptor (P2R) subtypes in the corpus cavernosum and urinary bladder, and determine whether changes in expression of these proteins correlate with development of erectile and bla...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.08337.x
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:To analyze pathological and short-term oncological outcomes in men undergoing open and minimally-invasive radical prostatectomy (MIRP) for high-risk prostate cancer (HRPC; prostate-specific antigen level [PSA] >20 ng/mL, ≥ cT2c, Gleason score 8-10) in a contemporaneous series. PATIENTS AND METHODS:In total,...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2012.11757.x
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVES:To examine the results of open partial nephrectomy (OPN) over a 15-year period in a large UK teaching hospital and to compare results with other series including minimally invasive techniques, as nephron-sparing techniques are still under-utilized in the surgical treatment of renal carcinoma. A standardized ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.07829.x
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To examine glucose-regulated protein 78 (GRP78; a major molecular chaperone at the endoplasmic reticulum, strongly expressed in several tumours) expression in urothelial carcinoma (UC) of the upper urinary tract (UUT) and to evaluate the diagnostic and progressive importance of GRP78 expression in UC-UUT. PA...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2009.09144.x
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVES:To review our experience at a children's hospital over a 10-year period with the Palomo, Ivanissevich, subinguinal and laparoscopic techniques for varicocele, assessing the success and complication rates according to specific procedure, and the added effect that the modifications of microsurgery and artery-s...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.08288.x
更新日期：2009-07-01 00:00:00
abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Systems for image guidance during laparoscopic surgery can be broadly defined as systems that enable the surgeon to refer to preoperatively gathered information during the procedure. For a laparoscopic system the preoperative information can be overl...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2012.11692.x
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the tissue yield of a new core-biopsy needle with an end-cut mechanism when used for transrectal prostate biopsies. PATIENTS AND METHODS:The end-cut instrument has an adjustable stroke length (13, 23 or 33 mm) and an inner and an outer cannula, but no trocar. It was compared with the conventional...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2002.02809.x
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVES:To investigate the receptors for angiotensin II (AII, reported to be a potent contractile agent in human urinary bladder), using functional and autoradiographic techniques in child and adult bladder specimens. Materials and methods Bladder specimens were obtained from 61 children (aged 4 months to 12 years) ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2000.00771.x
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To determine the partner's influence on the patient's choice of treatment for early prostate cancer, and whether partner characteristics and biases predict the preference. PATIENTS, SUBJECTS AND METHODS:Questionnaires for partners to complete retrospectively were sent to consecutive patients recruited in a s...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2003.04355.x
更新日期：2003-09-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06541.x
更新日期：2007-02-01 00:00:00
abstract：OBJECTIVE:To determine the effects of cycling oestrogen in rabbits, as oestrogen is essential for physiological maintenance and integrity of the female urogenital tract. MATERIALS AND METHODS:Changes in circulating oestrogen have marked effects on the bladder of experimental animals, with ovariectomy (Ovx) inducing sm...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.06532.x
更新日期：2007-01-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章,随机对照试验
doi：10.1111/bju.12926
更新日期：2015-05-01 00:00:00
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journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.07158.x
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To determine the value of measuring serum concentrations of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in patients with benign prostatic hyperplasia (BPH), advanced and localized prostate cancer, and thus assess the role of angiogenesis factors as markers of malignancy...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00363.x
更新日期：1999-12-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1111/j.1464-410X.2011.10053.x
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility of using a ganglial culture system to screen various growth factors as potential therapeutic agents for pelvic nerve injuries. MATERIALS AND METHODS:The major pelvic ganglia (MPG) were isolated from male rats and attached to culture dishes with the aid of Matrigel (Becton Dicki...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2003.04439.x
更新日期：2003-10-01 00:00:00
abstract：:For the delivery of good-quality external beam radiotherapy (EBRT) in localized prostate cancer, under-dosage to the peripheral zone (tumour) is one likely cause of poor results. The quality is improved by daily verification of the position of the prostate, and the use of magnetic resonance imaging (MRI) in delineatio...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1111/j.1464-410X.2007.07346.x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To present the long-term outcome of patients with locally advanced or metastatic prostate carcinoma treated by first-line antiandrogen monotherapy. PATIENTS AND METHODS:From 1983 to 1990, 41 patients with advanced prostate carcinoma were treated with flutamide monotherapy until progression or the appearance ...
journal_title：BJU international
pub_type： 临床试验,杂志文章
doi：10.1046/j.1464-410x.2003.04413.x
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:To create an experimental animal model to examine changes in bladder volume and histology after bladder augmentation in growing individuals and from the model, evaluate a method using demucosalized intestinal grafts and short-term bladder drainage. MATERIALS AND METHODS:The study comprised 21 piglets: in gro...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00895.x
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:To evaluate contrast-enhanced ultrasonography (US) using cadence-contrast pulse sequencing (CPS) technology, compared with systematic biopsy for detecting prostate cancer, as grey-scale US has low sensitivity and specificity for detecting prostate cancer. PATIENTS AND METHODS:In all, 44 men with suspicious p...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.08038.x
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the safety and effectiveness of the Seldinger technique by non-urology trained (NUT) doctors for difficult male indwelling urinary catheter (IDC) insertions. PATIENTS AND METHODS:In all, 115 patients and 57 participating NUT doctors were recruited by the urologist or urology registrar, when conta...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1111/bju.13928
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the comparative effectiveness of electromyographic (EMG) biofeedback with verbal instructions as learning tools of pelvic muscle exercises (PMEs) in the early management of urinary incontinence after radical prostatectomy. PATIENTS AND METHODS:Forty-two consecutive patients (mean age 64 years, sd...
journal_title：BJU international
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1046/j.1464-410x.2002.02721.x
更新日期：2002-05-01 00:00:00
abstract：:To compare the incidence of infective complications after transrectal ultrasonography (TRUS)-guided biopsy with either empirical fluoroquinolone or culture-based targeted antimicrobial prophylaxis, and the prevalence of fluoroquinolone resistance (FQ-R) in men undergoing prostate biopsy. A systematic review of the lit...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1111/bju.13402
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:To characterize a newly established human testicular carcinoma cell line that continuously produces alpha-fetoprotein (AFP), and to investigate the effects of retinoic acid on AFP production. MATERIALS AND METHODS:A 24-year-old man underwent a radical orchidectomy for a right testicular tumour and was found ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.2001.02357.x
更新日期：2001-10-01 00:00:00
