Abstract:
OBJECTIVE:• To analyse the overall and type-specific human papillomavirus (HPV) prevalence and distribution in penile carcinoma and determine the correlation to histopathological parameters. PATIENTS AND METHODS:• In this retrospective study, we analysed HPV status in 241 patients with penile carcinoma, treated at Örebro University Hospital, Örebro, Sweden, between 1984 and 2008. Age and date at diagnosis was recorded. • The tumour specimens were categorized according to the UICC 2002 TNM classification. A subset of patients was operatively staged with regard to lymph node status. • A commercially available Real Time PCR was used to detect 13 different types of HPV (6,11,16,18,31,33,35,45,51,52,56,58 and 59). RESULTS:• We excluded 25 patients due to low DNA quality. Of the remaining 216, 179 (82.9%) tumour specimens were HPV infected. The majority of cases positive for HPV (70.4%) were infected by a single-type. The most frequent type was HPV 16 followed by HPV 18. • No significant association between HPV status and pathological tumour stage, grade or lymph node status was found. CONCLUSION:• The HPV prevalence found is higher than in most other studies, further strengthening HPV as an etiological agent in penile carcinoma. Furthermore, the high prevalence of HPV 16 and 18 raises the question of what potential impact current HPV vaccines that target these specific HPV types might have on penile carcinoma. No significant association between HPV status and histopathological parameters was found in the present study. Additional investigations are needed to draw final conclusions on the prognostic value of HPV status in penile carcinoma.
journal_name
BJU Intjournal_title
BJU internationalauthors
Kirrander P,Kolaric A,Helenius G,Windahl T,Andrén O,Stark JR,Lillsunde-Larsson G,Elgh F,Karlsson Mdoi
10.1111/j.1464-410X.2010.09770.xsubject
Has Abstractpub_date
2011-08-01 00:00:00pages
355-9issue
3eissn
1464-4096issn
1464-410Xjournal_volume
108pub_type
杂志文章abstract:OBJECTIVE:To develop and validate an Arabic version of the International Prostate Symptom Score (IPSS). PATIENTS, SUBJECTS AND METHODS:An Arabic version of the IPSS (IPSS-Arb) was developed through a series of translations and modifications which involved the authors, urology and non-urology medical and nursing staff....
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08984.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To review the results of repairing a parastomal hernia after ileal conduit formation, using the lateral approach. PATIENTS AND METHODS:We retrospectively assessed 18 patients (9%) who developed a parastomal hernia, from 211 who had an ileal conduit created between 1982 and 2001; 15 had a surgical repair usin...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.05008.x
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To assess the sensitivity and specificity of blue-light cystoscopy (BLC) with hexaminolevulinate as an adjunct to white-light cystoscopy (WLC) vs WLC alone for the detection of non-muscle-invasive bladder cancer (NMIBC), in routine clinical practice in Spain. PATIENTS AND METHOD:An intra-patient comparative,...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.13020
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To compare the effects of diuresis induced by a loop diuretic (frusemide), an osmotic diuretic (mannitol) and a high-osmolar radio-contrast medium (sodium iothalamate) on the intrarenal resistive index (RI) in dogs with chronic unilateral partial ureteric obstruction (UPUO). MATERIALS AND METHODS:The split r...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02830.x
更新日期:2002-07-01 00:00:00
abstract::• Synthetic mid-urethral slings (MUSs) are considered the first choice surgical procedure for stress urinary incontinence. Recent publications have raised concerns about the efficacy of third generation single-incision mini-slings. The present paper is a systematic review of studies reporting 12-month outcomes after t...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2011.10333.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To assess the potentiation of erectile responses induced by electrical stimulation (ES) of the dorsal penile nerve (DPN) in the urethane-anaesthetized rat by the selective melanocortin receptor 4 agonist MB243. MATERIALS AND METHODS:Intracavernosal and blood pressures (ICP and BP, respectively) were monitore...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07751.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To report the long-term results with the Mainz Pouch II procedure. PATIENTS AND METHODS:Between 1990 and 2000 a Mainz Pouch II ureterosigmoidostomy was used in 123 patients (49 females and 74 males, mean age 43.6 years, range: 1-73). The indications for urinary diversion were cystectomy for bladder cancer in...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2003.04777.x
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To determine the effect of various treatments for benign prostatic hyperplasia (BPH) on sexual function. PATIENTS AND METHODS:In a longitudinal multicentre study carried out in the Netherlands, 670 consecutive patients with BPH (aged > or = 50 years) were examined at baseline and 9 months after inclusion. Al...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1464-4096.2001.01817.x
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:• To investigate the feasibility of tissue-engineered corpus cavernosum (TECC) with muscle-derived stem cells (MDSCs) as seed cells and determine the growth potential in vivo. MATERIALS AND METHODS:• Acellular corporal collagen matrices (ACCMs) were obtained from adult rabbit penis by a cell removal procedur...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09695.x
更新日期:2011-05-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? The relationship between high levels of BMI and changes in altered standard semen analysis parameters are described in the literature. However, the functional characteristics of the sperm are essential to complete the evaluation of male infertility. T...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10813.x
更新日期:2012-09-01 00:00:00
abstract:UNLABELLED:Study Type--Therapy (case series). Level of Evidence 4. What's known on the subject? And what does the study add? Adverse outcomes after radical prostatectomy are more often recorded in the elderly. In the USA, elderly patients undergoing radical prostatectomy are treated at institutions where suboptimal out...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10554.x
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To demonstrate an ergonomic fourth arm technique to oversew the dorsal vascular complex (DVC) during robot-assisted laparoscopic prostatectomy (RALP). PATIENTS AND METHODS:Balloon of a Foley catheter inflated in the bulbar urethra. Fourth arm cranial traction via suture in the tip of the catheter. DVC overse...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11716.x
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:• To evaluate the efficacy and safety of single-agent AMG 102, an investigational, fully human monoclonal antibody to hepatocyte growth factor/scatter factor (HGF/SF), in renal cell carcinoma (RCC). PATIENTS AND METHODS:• This open-label phase II study included patients ≥ 18 years old with histologically con...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09947.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07059.x
更新日期:2007-10-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410x.2004.04577.x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To assess the potential of p21 as a gene therapy treatment for prostate cancer, by introducing p21 into both androgen-dependent (AD) and -independent (AI) human prostate cancer cell lines via a recombinant adenoviral vector, Ad5CMV-p21, carrying human p21 cDNA. MATERIALS AND METHODS:The LNCaP, DU145 and PC-3...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04318.x
更新日期:2003-08-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15088
更新日期:2020-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07192.x
更新日期:2008-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07735.x
更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09566.x
更新日期:2011-03-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/bju.14849
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To describe the incidence, prevalence and management of lower urinary tract symptoms (LUTS), suggestive of benign prostatic hyperplasia, reported in UK general practice. PATIENTS AND METHODS:All clinical information relating to LUTS and its treatment was assessed for men aged > or = 45 years and registered o...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05339.x
更新日期:2005-03-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15019
更新日期:2020-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.10968.x
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To describe and assess the evolution of an enhanced recovery programme (ERP) for open radical cystectomy. PATIENTS AND METHODS:We introduced a mentored ERP for radical cystectomy in January 2011. The programme underwent service evaluation and multiple changes in August 2012 that we define as marginal gains. ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12644
更新日期:2014-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08547.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To assess the outcome of different forms of urinary drainage, particularly for urinary tract infection (UTI), operative findings and patient preference, in patients treated for acute urinary retention (AUR). PATIENTS AND METHODS:A feasibility trial was conducted of men presenting with AUR; after a short peri...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02253.x
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVES:To define the perioperative morbidity and 30-day mortality of cytoreductive nephrectomy (CN) using the British Association of Urological Surgeons (BAUS) nephrectomy dataset for 2012, the first year of public reporting of individual surgeon outcomes in the UK. PATIENTS AND METHODS:All nephrectomies recorded ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12890
更新日期:2015-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08609.x
更新日期:2010-01-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and what does the study add?: Variations in the type of urinary diversion exist for patients undergoing radical cystectomy. Although its use has been increasing from 2001 to 2008, patients who are older, female, and primary insured by Medicaid are less likely to receive continent...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11508.x
更新日期:2013-08-01 00:00:00