Association between obesity and alteration of sperm DNA integrity and mitochondrial activity.

abstract：OBJECTIVE:To examine the tissue expression of DNA topoisomerase I (Topo I) and IIalpha (Topo II), to pursue the possibility of future chemotherapy regimens for squamous cell carcinoma of the penis (SCCP), as high expression of Topo I might indicate sensitivity to the camptothecins, whereas high Topo II might indicate s...

journal_title：BJU international

authors： Berney DM,Stankiewicz E,Adlan AM,Kudahetti S,Biedrzycki OJ,Hadway P,Watkin N,Corbishley C

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To compare high-power holmium laser lithotripsy (HP-HLL) and ultrasonic lithotripsy (US-L) for disintegration of staghorn stones during percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS:A non-inferiority randomised controlled trial was conducted between August 2011 and September 2014. Inclusion crite...

journal_title：BJU international

authors： El-Nahas AR,Elshal AM,El-Tabey NA,El-Assmy AM,Shokeir AA

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To describe our current procedure of robot-assisted laparoscopic radical prostatectomy (RALP), and to assess the effect of the learning curve on perioperative data, early oncological outcomes and functional results, as RALP has increasingly become a treatment option for men with localized prostate cancer. PA...

journal_title：BJU international

authors： Ploussard G,Xylinas E,Salomon L,Vordos D,Hoznek A,Abbou CC,De La Taille A

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...

journal_title：BJU international

authors： Schoeppler GM,Buchner A,Zaak D,Khoder W,Staehler M,Stief CG,Reiser MF,Clevert DA

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:To identify biomarkers that predict the response to standard androgen deprivation therapy (ADT) of patients newly diagnosed with metastatic castration-sensitive prostate cancer (CSPC) in order to improve therapeutic decision-making, and to investigate whether the characterization of baseline circulating tumo...

journal_title：BJU international

authors： Yang YJ,Kong YY,Li GX,Wang Y,Ye DW,Dai B

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To characterize the clinical outcomes of androgen deprivation therapy (ADT) as the sole therapy for localized prostate cancer, and to determine independent predictors of disease progression, as recent studies indicate an increasing use of ADT. PATIENTS AND METHODS:The records of all patients with cT1-4NXM0 a...

journal_title：BJU international

authors： Janoff DM,Peterson C,Mongoue-Tchokote S,Peters L,Beer TM,Wersinger EM,Mori M,Garzotto M

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the comparative effectiveness of electromyographic (EMG) biofeedback with verbal instructions as learning tools of pelvic muscle exercises (PMEs) in the early management of urinary incontinence after radical prostatectomy. PATIENTS AND METHODS:Forty-two consecutive patients (mean age 64 years, sd...

journal_title：BJU international

authors： Floratos DL,Sonke GS,Rapidou CA,Alivizatos GJ,Deliveliotis C,Constantinides CA,Theodorou C

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To present the outcomes of cT3N0M0 prostate cancer after radical prostatectomy (RP) and determine the prognostic factors in biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS), cancer-specific survival (CSS) and overall survival (OS) after long-term follow-up of 10 years. ...

journal_title：BJU international

authors： Hsu CY,Wildhagen MF,Van Poppel H,Bangma CH

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To determine the role of hypoxia-inducible factor-2alpha (HIF2alpha) on the sensitivity of renal cell carcinoma (RCC) cell lines to ionizing radiation and to determine if the mTOR antagonist, rapamycin, could decrease HIF2alpha protein levels. MATERIALS AND METHODS:Cell lines expressing stable short-hairpin ...

journal_title：BJU international

authors： Bhatt RS,Landis DM,Zimmer M,Torregrossa J,Chen S,Sukhatme VP,Iliopoulos O,Balk S,Bubley GJ

更新日期：2008-08-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? Percutaneous renal cryoablation is a safe and effective treatment for patients with small renal masses, who are poor surgical candidates. Oncological outcomes from previous percutaneous ablation studies are difficult to interpret because of the large ...

journal_title：BJU international

authors： Schmit GD,Thompson RH,Kurup AN,Weisbrod AJ,Carter RE,Callstrom MR,Atwell TD

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To report the medium-term results at our institution of repairing long bulbar urethral strictures with buccal mucosal grafts. PATIENTS AND METHODS:Between January 2003 and June 2007, a buccal mucosa graft repair was used in 34 patients with recurrent bulbar strictures >2 cm. The follow-up included uroflowme...

journal_title：BJU international

authors： Fransis K,Vander Eeckt K,Van Poppel H,Joniau S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the possible influence of non-pharmacological interventions, such as compressive bandages and intermittent pneumatic compression (IPC), on leg oedema and nocturnal polyuria (NP), and the possible interrelation between both pathologies in patients with spinal cord injury (SCI), as patients with SC...

journal_title：BJU international

authors： Viaene A,Roggeman S,Goessaert AS,Kessler TM,Mehnert U,Besien VV,De Muynck M,Everaert K

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between glycogen content in bladder detrusor tissue and historical bladder function in a guinea-pig model of partial bladder outlet obstruction (PBOO). MATERIALS AND METHODS:In male immature guinea pigs PBOO was created with a silver ring around the proximal urethra; a control grou...

journal_title：BJU international

authors： de Jong BW,Wolffenbuttel KP,Arentshorst ME,Lodder P,Kok DJ

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To develop a generator for high-intensity focused ultrasound (HIFU, a method of delivering ultrasonic energy with resultant heat and tissue destruction to a tight focus at a selected depth within the body), designed for extracorporeal coupling to allow various parenchymal organs to be treated. MATERIAL AND M...

journal_title：BJU international

authors： Köhrmann KU,Michel MS,Steidler A,Marlinghaus E,Kraut O,Alken P

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:to investigate the effect of menopausal transition and age on symptoms of urinary incontinence in midlife. SUBJECTS AND METHODS:the study included a nationally representative cohort of 1211 women followed up since their birth in 1946 and annually from 48-54 years; their menopausal transition status and sympt...

journal_title：BJU international

authors： Mishra GD,Cardozo L,Kuh D

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To explain differences over time between operative approach and surgeon type for adrenal surgery in the USA. PATIENTS AND METHODS:A retrospective cohort analysis was performed on all patients undergoing adrenalectomy between 2002 and 2011 using the Nationwide Inpatient Sample. Patients undergoing concurrent ...

journal_title：BJU international

authors： Monn MF,Calaway AC,Mellon MJ,Bahler CD,Sundaram CP,Boris RS

更新日期：2015-02-01 00:00:00

abstract：:There has been a recent increase in mumps orchitis among pubertal and postpubertal males. These outbreaks can be attributed to a reduction in the uptake of measles-mumps-rubella (MMR) vaccine during the early to mid-1990 s in children who have now matured. The mumps virus is commonly associated with extra-salivary com...

journal_title：BJU international

authors： Davis NF,McGuire BB,Mahon JA,Smyth AE,O'Malley KJ,Fitzpatrick JM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To test the replicability and robustness of findings about urological symptoms in men and women, classified using an objective statistical method, cluster analysis, by planned sensitivity analyses conducted within and across two large, epidemiological studies of lower urinary tract symptoms. METHODS:Sensitiv...

journal_title：BJU international

authors： Rosen RC,Coyne KS,Henry D,Link CL,Cinar A,Aiyer LP,Mollon P,Kaplan SA,Roehrborn CG,Thompson C

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To obtain a greater understanding of sexual behaviour and habits among men with and without erectile dysfunction (ED), and their female partners, to improve the management of ED in heterosexual men. SUBJECTS AND METHODS:A population-based study was conducted amongst men and women aged > 40 years. None of the...

journal_title：BJU international

authors： Eardley I,Dean J,Barnes T,Kirby M,Glasser D,Solanki J

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To assess the use of mitomycin C, by urologists within the UK, as a single-dose intravesical agent. Current European recommendations are to use one dose after any new tumour resection. METHODS:We assessed the current patterns of mitomycin C usage amongst British urologists, particularly with reference to one...

journal_title：BJU international

authors： Clarke NS,Basu S,Prescott S,Puri R

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To develop and validate an in vitro method suitable for the quantitative investigation of the growth of calcium oxalate stones through to a clinically significant size. MATERIALS AND METHODS:Small fragments of calcium oxalate calculi were suspended in a mixed suspension/mixed product removal crystalliser sup...

journal_title：BJU international

authors： Ananth K,Kavanagh JP,Walton RC,Rao PN

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the perioperative, postoperative and functional outcomes of robot-assisted partial nephrectomy (RAPN) for renal tumours with high surgical complexity at a large volume centre. PATIENTS AND METHODS:Perioperative and functional outcomes of RAPNs for renal tumours with a Preoperative Aspects and Dim...

journal_title：BJU international

authors： Volpe A,Garrou D,Amparore D,De Naeyer G,Porpiglia F,Ficarra V,Mottrie A

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To ascertain the prevalence of lower urinary tract symptoms (LUTS) and urinary incontinence (UI) in Canada, using a cross-Canada telephone survey, as there is a wide discrepancy in the reported prevalence of these conditions. SUBJECTS AND METHODS:A random survey with a standardized questionnaire was conducte...

journal_title：BJU international

authors： Herschorn S,Gajewski J,Schulz J,Corcos J

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To assess the rate of prostate-specific antigen (PSA) testing for prostate cancer in general practice in asymptomatic and symptomatic patients. SUBJECTS AND METHODS:The cross-sectional study took place in England and Wales, was population-based and covered 469 159 men aged 45-84 years. Pathology data on PSA ...

journal_title：BJU international

authors： Melia J,Moss S,Johns L,Contributors in the participating laboratories.

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of OnabotulinumtoxinA (BTXA) injections in men with drug-refractory non-neurogenic overactive bladder (NNOAB). PATIENTS AND METHODS:A total of 43 men received BTXA injections for NNOAB from 2004 to 2012. Patient Global Impression of Improvement (PGI-I) score was obtained. For men with ...

journal_title：BJU international

authors： Habashy D,Losco G,Tse V,Collins R,Chan L

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To compare prospectively obtained symptom scores (pre-tests) with retrospective assessment (then-tests) in patients with newly diagnosed advanced prostate cancer. PATIENTS AND METHODS:Patients with newly diagnosed locally advanced or metastatic prostate cancer were recruited. They completed the International...

journal_title：BJU international

authors： Rees J,Waldron D,O'Boyle C,Ewings P,MacDonagh R

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of asymptomatic bacteriuria (ABU) and urinary tract infection (UTI), and the local and systemic inflammatory response, in patients with ileal neobladder. PATIENTS AND METHODS:The study included 40 patients who had a radical cystectomy and ileal neobladder. Two urine samples, one...

journal_title：BJU international

authors： Suriano F,Gallucci M,Flammia GP,Musco S,Alcini A,Imbalzano G,Dicuonzo G

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between the levels of glycosylated haemoglobin (HbA1c) and the severity of erectile dysfunction (ED) in men with diabetes mellitus (DM). PATIENTS AND METHODS:This cross-sectional study included sexually active men with a diagnosis of DM attending a urological medical centre from J...

journal_title：BJU international

authors： Rhoden EL,Ribeiro EP,Riedner CE,Teloken C,Souto CA

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To develop and test the safety and feasibility of a novel anti-biofilm mechanism configured for wireless capsule endoscopy (WCE) in a sheep bladder model. MATERIALS AND METHODS:A WCE mechanism, designed for long-term bladder monitoring, was developed and introduced into a sheep bladder for 5 months. The tran...

journal_title：BJU international

authors： Neheman A,Schulman C,Yossepowitch O

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To investigate whether fluid shear stress (FSS) induces endothelial nitric oxide synthase (eNOS) activity and NO production in isolated human corpus cavernosal endothelial cells (HCCECs), and whether this response is altered during hyperglycaemia in vitro, as haemodynamic signalling during penile erection ind...

journal_title：BJU international

authors： Wessells H,Teal TH,Engel K,Sullivan CJ,Gallis B,Tran KB,Chitaley K

更新日期：2006-05-01 00:00:00