Xanthogranulomatous pyelonephritis: presentation and management in the era of laparoscopy.

Abstract:

OBJECTIVE:To report a contemporary series of patients with xanthogranulomatous pyelonephritis (XGP, an inflammatory condition of the kidney that has traditionally been treated with open nephrectomy, ON), managed with either ON or laparoscopic nephrectomy (LN), as early reports suggest that the benefits of LN do not extend to patients with XGP. PATIENTS AND METHODS:The medical and procedural records of patients with pathologically confirmed XGP between December 1993 to February 2004 were reviewed retrospectively. During this period, 26 patients (mean age 43.5 years, range 17-85) had surgical management of XGP; information on the mode of presentation, surgical management, hospital course and complications were analysed. RESULTS:Twelve (46%) and 14 (54%) patients had ON and LN, respectively. The LN group had significantly lower blood loss (P = 0.002), transfusion rates (P = 0.02), time to resumption of oral intake (P = 0.002) and length of hospital stay (P = 0.002) than the ON group. One (7%) LN was converted to ON due to failure to progress. The overall complication rates between the ON and LN groups were not significantly different (P = 0.95). CONCLUSIONS:LN in the setting of XGP is often difficult and requires advanced laparoscopic skills. In highly selected patients this approach can be offered, with acceptable morbidity, allowing for lower blood loss and shorter convalesce times.

journal_name

BJU Int

journal_title

BJU international

authors

Guzzo TJ,Bivalacqua TJ,Pierorazio PM,Varkarakis J,Schaeffer EM,Allaf ME

doi

10.1111/j.1464-410X.2009.08547.x

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

1265-8

issue

9

eissn

1464-4096

issn

1464-410X

pii

BJU8547

journal_volume

104

pub_type

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