Abstract:
OBJECTIVE:To evaluate a group of young women undergoing complex vaginoplasty, which may be defined as where there has already been previous complex pelvic surgery and the patient is unsuitable for conservative treatment or minor surgical revision. PATIENTS AND METHODS:All patients who had undergone a complex vaginoplasty between 1997 and 2004 were reviewed retrospectively. Information was recorded on the underlying condition, previous surgery and preoperative assessment. The operative technique and complications were noted, and the outcome in terms of menstruation and sexual activity. In all, 15 patients fulfilled the criteria (mean age 22.2 years, range 17-36) and the mean follow-up was 4.75 (0.75-7) years. RESULTS:Fourteen patients had complex congenital anomalies of the lower genital tract and 11 of these had associated anomalies of the urinary and gastrointestinal system; four were XY females. The 15 patients had had 31 vaginal procedures, including ileal vaginoplasty, mobilization of perineal skin flaps and split-skin grafting. Three patients required osteotomies to increase pelvic outlet diameter. The commonest complications were stenosis (six patients) and fistula formation (four). Eight patients are now sexually active; the remaining seven have not attempted sexual intercourse. CONCLUSIONS:Complications are common and can be major; most patients require many repeat operations to achieve a patent vagina. Unfortunately at present, this is the only option for this group of young women to achieve a functional vagina. Patients with complex congenital anomalies of the reproductive and genital tracts are increasingly surviving into adulthood, and the numbers of these patients is likely to increase in the future.
journal_name
BJU Intjournal_title
BJU internationalauthors
Davies MC,Creighton SM,Woodhouse CRdoi
10.1111/j.1464-410X.2005.05522.xkeywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
1293-8issue
9eissn
1464-4096issn
1464-410Xpii
BJU5522journal_volume
95pub_type
杂志文章abstract:OBJECTIVES:To examine the efficacy of intralesional collagenase Clostridium histolyticum (CCH) in defined subgroups of patients with Peyronie's disease (PD). PATIENTS AND METHODS:The efficacy of CCH compared with placebo, assessed from baseline to week 52, was examined in subgroups of participants from the Investigati...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.13096
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the insertion of a urethral sling at the time of radical prostatectomy (RP) in men at high risk of urinary incontinence after RP. PATIENTS AND METHODS:Between 1998 and 2000, 49 of 871 men undergoing RP at The University of Texas M.D. Anderson Cancer Center, were identified as at risk of urinary i...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06220.x
更新日期:2006-08-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07580.x
更新日期:2008-07-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10805.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To determine the relationship of age to side-effects leading to discontinuation of treatment in patients with stage Ta-T1 non-muscle-invasive bladder cancer (NMIBC) treated with maintenance bacille Calmette-Guérin (BCG). PATIENTS AND METHODS:We evaluated toxicity for 487 eligible patients with intermediate- ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.13474
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To interrogate enriched prostate cancer cells and autologous non-malignant prostate epithelial cells from men with localized prostate cancer, in order to identify early oncogenic pathways. PATIENTS AND METHODS:We collected malignant and matched non-malignant prostatectomy samples from men with adenocarcinoma...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14695
更新日期:2019-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04020.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To help clarify which small renal cortical neoplasms (RCNs) require surgery by using office-based, ultrasonography-guided percutaneous renal biopsy. PATIENTS AND METHODS:Biopsies were performed using facilitated ultrasound targeting (FUT) technology, which incorporates a needle guide and onscreen beam-steer...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12489
更新日期:2016-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.1999.00895.x
更新日期:1999-02-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05359.x
更新日期:2005-03-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06010.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To provide comparative data on quality of life (QoL) after prostate cancer treatment to help patients make an informed decision regarding their choice of treatment. METHODS:Patients with pathologically proven, non-metastatic, T1-T3bN0 prostate cancer were included in this prospective non-randomized study if ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14021
更新日期:2018-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04237.x
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To assess the early disclosure and treatment of meatal stenosis after hypospadias repair, using calibration of the neourethral meatus at regular intervals to detect stenosis, and to assess the curative effects of dilatation with topical corticosteroids. PATIENTS AND METHODS:Between 2001 and 2003, 83 boys (me...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.05870.x
更新日期:2006-01-01 00:00:00
abstract::• Synthetic mid-urethral slings (MUSs) are considered the first choice surgical procedure for stress urinary incontinence. Recent publications have raised concerns about the efficacy of third generation single-incision mini-slings. The present paper is a systematic review of studies reporting 12-month outcomes after t...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2011.10333.x
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of prostate weight on perioperative, functional and oncological outcomes after laparoscopic radical prostatectomy (LRP). PATIENTS AND METHODS:Between January 2003 and January 2006, 327 patients had LRP by one surgeon, 193 of whom were available for analysis. Patients were stratified in...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07263.x
更新日期:2008-03-01 00:00:00
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journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/bju.14703
更新日期:2019-08-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11766.x
更新日期:2013-08-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/bju.12926
更新日期:2015-05-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.12580
更新日期:2014-11-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08033.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:• To evaluate the combination of multiple magnetic resonance imaging (MRI) techniques, including T2-weighted imaging (T2W), dynamic contrast-enhanced imaging (DCE) and diffusion-weighted imaging (DWI), for the detection and localization of prostate cancer. PATIENTS AND METHODS:• In all, 57 patients underwent...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09808.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To examine the effect of the dual-action 5alpha-reductase inhibitor dutasteride on benign prostatic hyperplasia (BPH)-specific health status, as measured by the BPH Impact Index (BII), and to identify baseline and treatment risk factors for those most bothered by their BPH symptoms at the end of the protocol...
journal_title:BJU international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1464-410x.2003.04310.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To study a novel penile reinnervation technique using four sural nerve grafts and end-to-side neurorraphies connecting bilaterally the femoral nerve and the cavernous corpus and the femoral nerve and the dorsal penile nerves. PATIENTS AND METHODS:Ten patients (mean [± sd; range] age 60.3 [± 4.8; 54-68] years...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13772
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To correlate the results of intraoperative cavernous nerve stimulation (CaNS) at radical prostatectomy (RP), with preoperative erectile function (EF) and to determine the significance of the results of stimulation after RP in predicting the recovery of EF. PATIENTS AND METHODS:The study included 183 potent m...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.08519.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To describe the characteristics of patients with and without positive surgical margins (PSMs) and to analyse the impact of PSMs on secondary cancer treatment after radical prostatectomy (RP), with short-term follow-up. PATIENTS AND METHODS:We analysed data from 2385 consecutive patients treated using RP, who...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12509
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:• To study the association between specific clinical symptoms (e.g. low libido and erectile dysfunction) and testosterone levels and age in order to define symptom-specific testosterone thresholds. MATERIALS AND METHODS:• Serum samples for testosterone determination were obtained from 675 healthy men. • Part...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09986.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To identify significant prognostic indicators of upper urinary tract (UUT) urothelial carcinoma (UC) and to assess a risk stratification of patients. PATIENTS AND METHODS:We retrospectively analysed data from 162 patients with non-metastatic UC primarily occurring in UUT treated with open nephroureterectomy....
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08134.x
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of obstructive sleep apnoea (OSA) in men presenting with erectile dysfunction (ED) at a single centre. PATIENTS AND METHODS:All men attending a specialised andrology outpatient department with a new diagnosis of ED were included in this prospective study. All patients completed three...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13961
更新日期:2017-12-01 00:00:00
abstract:UNLABELLED:Study Type--Clinical (prospective trial) Level of Evidence 2b. What's known on the subject? and What does the study add? In clinical practice, we know that it is necessary to identify new biomarkers that can better detect prostate cancer (PC), at the same time as reducing the number of unnecessary biopsies. ...
journal_title:BJU international
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1464-410X.2012.11146.x
更新日期:2012-12-01 00:00:00