Efficacy of nilutamide as secondary hormonal therapy in androgen-independent prostate cancer.

abstract：OBJECTIVE:to investigate the effect of menopausal transition and age on symptoms of urinary incontinence in midlife. SUBJECTS AND METHODS:the study included a nationally representative cohort of 1211 women followed up since their birth in 1946 and annually from 48-54 years; their menopausal transition status and sympt...

journal_title：BJU international

authors： Mishra GD,Cardozo L,Kuh D

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:• To present a novel method of renal ablation using direct current electrolysis, using a porcine model to assess the safety and efficacy of the technique. MATERIALS AND METHODS:• In all, 20 anaesthetised pigs were used, after receiving ethical approval. The pigs were housed and managed in accordance with Ins...

journal_title：BJU international

authors： Lloyd M,Miller J,Moretti KL,Texler M,Maddern GJ

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To determine the optimal contractile response of isolated ureters to inflammatory mediators and neurotransmitters by evaluating four common methods of ureteric suspension. MATERIALS AND METHODS:Ureters from adult domestic swine were placed immediately in Krebs buffer and cut into 4-5 mm segments. Four method...

journal_title：BJU international

authors： Jerde TJ,Saban R,Nakada SY

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To provide an up-to-date summary of current literature on the management of adverse effects of androgen-deprivation therapy (ADT). PATIENTS AND METHODS:All relevant medical literature on men with prostate cancer treated with ADT from 2005 to 2014, and older relevant papers, were reviewed. Recent health advis...

journal_title：BJU international

authors： Rhee H,Gunter JH,Heathcote P,Ho K,Stricker P,Corcoran NM,Nelson CC

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To measure the time and subjective quality of individual steps of robot-assisted radical prostatectomy (RARP), as RARP performed by trainees has recently become the most common technique of RP in the USA, and although outcomes from expert surgeons are reported, limited data are available to document training ...

journal_title：BJU international

authors： Davis JW,Kamat A,Munsell M,Pettaway C,Pisters L,Matin S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To investigate the antitumour effect of electroporation (EP), a drug delivery system that has been shown to be effective synergistically with antitumour drugs, with bleomycin on the growth of prostate cancer xenografts in nude mice. MATERIALS AND METHODS:PC-3 cells were implanted subcutaneously into nude mic...

journal_title：BJU international

authors： Ueki T,Uemura H,Nagashima Y,Ohta S,Ishiguro H,Kubota Y

更新日期：2008-11-01 00:00:00

abstract：:What's known on the subject? and What does the study add? The suppressor effect of probiotics on superficial bladder cancer is an observed phenomenon but the specific mechanism is poorly understood. The evidence strongly suggests natural killer (NK) cells are the anti-tumour effector cells involved and NK cell activit...

journal_title：BJU international

authors： Feyisetan O,Tracey C,Hellawell GO

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To determine the changes in cyclooxygenase-2 (COX-2), E-cadherin and alpha-catenin expression after partial bladder outlet obstruction (PBOO), and whether a selective COX-2 inhibitor (celecoxib) might inhibit COX-2 expression and have beneficial effects on urothelial cell-to-cell interactions in rats subjecte...

journal_title：BJU international

authors： Erdogru T,Celik-Ozenci C,Seval Y,Emreoglu I,Ustunel I,Korgun E,Koksal TI,Baykara M,Demir R

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To explore the possibility that allogeneic responses might, by chance, encompass cross-reactive T cell clones specific for neo-antigenic tumour determinants, and thereby activate antitumour immunity; such cross-reactions are well documented for antiviral immunity, and genetic instability in developing cancers...

journal_title：BJU international

authors： Muir G,Rajbabu K,Callen C,Fabre JW

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To assess the effect of solifenacin succinate treatment on quality of life (QoL) measured in clinical trials in patients with overactive bladder (OAB). PATIENTS AND METHODS:QoL data using the King's Health Questionnaire (KHQ) were analysed from two phase-3, 12-week studies (1984 patients) and a long-term ext...

journal_title：BJU international

authors： Kelleher CJ,Cardozo L,Chapple CR,Haab F,Ridder AM

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To accurately define the anatomy of the neurovascular bundle (NVB) in men. MATERIALS AND METHODS:The NVB was microdissected in detail bilaterally in 12 fixed human male adult cadavers. The anatomy of the NVB and its relationship to surrounding pelvic structures was ascertained in each specimen. RESULTS:Prev...

journal_title：BJU international

authors： Costello AJ,Brooks M,Cole OJ

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between perineural invasion (PNI) on prostate biopsy and radical prostatectomy (RP) outcomes in a contemporary RP series, as there is conflicting evidence on the prognostic significance of PNI in prostate needle biopsy specimens. PATIENTS AND METHODS:From 2002 to 2007, 1256 men ...

journal_title：BJU international

authors： Loeb S,Epstein JI,Humphreys EB,Walsh PC

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects specific genetic events on these chromosomes or merely wider unspe...

journal_title：BJU international

authors： Bartlett JM,Adie L,Watters AD,Going JJ,Grigor KM

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of oxidized cellulose, Surgicel(TM) (Johnson & Johnson Medical, New Brunswick, NJ, USA) for patching defects in the tunica albuginea in a rabbit model, with a future application to correct chordee. MATERIALS AND METHODS:The study comprised nine New Zealand white male rabbits; a recta...

journal_title：BJU international

authors： El-Assmy A,Eassa W,El-Hamid MA,Nour EM,Hafez AT

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To assess the factors that influence the onset of androgen independence (AI, which heralds a dismal outcome) in patients with metastatic prostate carcinoma. PATIENTS AND METHODS:The records of 361 consecutive patients with prostate carcinoma diagnosed and treated in the authors' institution from 1 January 19...

journal_title：BJU international

authors： Sim HG,Lau WK,Cheng CW

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To explore the expression of transforming growth factor-beta(1) (TGF-beta1) in penile tissue from rats after bilateral cavernosal nerve (CN) ablation, mimicking patients who have had no nerve-sparing during prostatectomy. MATERIALS AND METHODS:Ten adult male rats (neurectomy group) had a bilateral CN resecti...

journal_title：BJU international

authors： Hu WL,Hu LQ,Li SW,Zheng XM,Tian BC

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential impact of alterations in 'patient' position on laser-induced ureteric stone retropulsion in an in vitro model. MATERIALS AND METHODS:A ceramic (phantom) stone was placed in a water-filled clear polymer tube and subjected to continuous laser energy until the stone had retropulsed a d...

journal_title：BJU international

authors： Patel RM,Walia AS,Grohs E,Okhunov Z,Landman J,Clayman RV

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinical significance of preoperative erythrocyte sedimentation rate (ESR) and neutrophil-lymphocyte ratio (NLR) as prognostic factors in patients undergoing radical nephroureterectomy for upper tract urothelial carcinoma (UTUC). PATIENTS AND METHODS:A total of 410 patients were retrospectiv...

journal_title：BJU international

authors： Sung HH,Jeon HG,Jeong BC,Seo SI,Jeon SS,Choi HY,Lee HM

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To identify significant prognostic indicators of upper urinary tract (UUT) urothelial carcinoma (UC) and to assess a risk stratification of patients. PATIENTS AND METHODS:We retrospectively analysed data from 162 patients with non-metastatic UC primarily occurring in UUT treated with open nephroureterectomy....

journal_title：BJU international

authors： Simone G,Papalia R,Loreto A,Leonardo C,Sentinelli S,Gallucci M

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To analyse the technical details and the long-term results of laparoscopic ureterolithotomy. PATIENTS AND METHODS:Laparoscopic ureterolithotomy was undertaken in 101 patients between 1991 and 2001; in only one patient with retroperitoneal fibrous adhesions was the procedure transperitoneal, being retroperito...

journal_title：BJU international

authors： Gaur DD,Trivedi S,Prabhudesai MR,Madhusudhana HR,Gopichand M

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To assess reports supporting the novel and comprehensive evidence-based pathway for radical prostatectomy (RP), as collaborative-care pathways have helped to optimize management of patients treated with RP and such clinical pathways provide an ideal framework for constructing an original evidence-based pathwa...

journal_title：BJU international

authors： Kaufman MR,Baumgartner RG,Anderson LW,Smith JA Jr,Chang SS,Herrell SD,Cookson MS

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...

journal_title：BJU international

authors： Hanna MY,Tremlett C,Josan G,Eltom A,Mills R,Rochester M,Livermore DM

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:• To study the operability and effectiveness of a biodegradable ureteral stent for clinical treatment of ureteral war injury using a canine model. MATERIALS AND METHODS:• A device was designed and employed to generate firearm fragment wounds in unilateral ureters (on randomly chosen sides) of nine beagles (G...

journal_title：BJU international

authors： Li G,Wang ZX,Fu WJ,Hong BF,Wang XX,Cao L,Xu FQ,Song Q,Cui FZ,Zhang X

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: In renal cell carcinoma the role of lymphadenectomy (LND) is still controversial. Moreover, no firm consensus exists regarding the minimum number of lymph nodes that should be removed to obtain a satisfactory staging LND at the time of surgery. Our f...

journal_title：BJU international

authors： Capitanio U,Suardi N,Matloob R,Abdollah F,Castiglione F,Briganti A,Carenzi C,Roscigno M,Montorsi F,Bertini R

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence, type and treatment behaviour of women with urinary incontinence in four European countries. SUBJECTS AND METHODS:Data were collected using a postal survey which was sent to 29,500 community-dwelling women aged > or = 18 years in France, Germany, Spain and the UK. Subjects were as...

journal_title：BJU international

authors： Hunskaar S,Lose G,Sykes D,Voss S

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To investigate the potential role of platelet-derived growth factor-AA (PDGF-AA) and the PDGF-α receptor as prognostic markers in Wilms' tumour. PATIENTS AND METHODS:The expression of PDGF-AA and PDGF-α were investigated using immunohistochemical analysis of 62 Wilms' tumours. Patients were treated with chem...

journal_title：BJU international

authors： Ghanem M,Nijman R,Safan M,van der Kwast T,Vansteenbrugge G

更新日期：2010-11-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The management of patients with non-obstructive azoospermia (NOA) involves testicular sperm extraction (TESE or microdissection TESE) combined with intracytoplasmic sperm injection (ICSI). Sperm retrieval is successful in up to 50% of men with NOA; h...

journal_title：BJU international

authors： Abdel Raheem A,Garaffa G,Rushwan N,De Luca F,Zacharakis E,Abdel Raheem T,Freeman A,Serhal P,Harper JC,Ralph D

更新日期：2013-03-01 00:00:00

abstract：UNLABELLED:Study Type--Therapy (cohort) Level of Evidence 2a. What's known on the subject? and What does the study add? Despite expanding treatment options for castration-resistant prostate cancer (CRPC), therapies with long response duration remain intangible due to prostate cancer cells' natural ability to develop it...

journal_title：BJU international

authors： Nakabayashi M,Werner L,Courtney KD,Buckle G,Oh WK,Bubley GJ,Hayes JH,Weckstein D,Elfiky A,Sims DM,Kantoff PW,Taplin ME

更新日期：2012-12-01 00:00:00

abstract：:Novel oral anti-coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing p...

journal_title：BJU international

authors： Ellis G,John Camm A,Datta SN

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To review the results of repairing a parastomal hernia after ileal conduit formation, using the lateral approach. PATIENTS AND METHODS:We retrospectively assessed 18 patients (9%) who developed a parastomal hernia, from 211 who had an ileal conduit created between 1982 and 2001; 15 had a surgical repair usin...

journal_title：BJU international

authors： Ho KM,Fawcett DP

更新日期：2004-09-01 00:00:00