Abstract:
OBJECTIVE:To provide an up-to-date summary of current literature on the management of adverse effects of androgen-deprivation therapy (ADT). PATIENTS AND METHODS:All relevant medical literature on men with prostate cancer treated with ADT from 2005 to 2014, and older relevant papers, were reviewed. Recent health advisory statements from the Australian government, societies and advocacy groups have been incorporated to the document. RESULTS:There are numerous adverse effects of ADT that require pro-active prevention and treatment. Ranging from cardiovascular disease, diabetes and osteoporosis, to depression, cognitive decline and sexual dysfunction, the range of adverse effects is wide. Baseline assessment, monitoring, prevention and consultation from a multidisciplinary team are important in minimising the harm from ADT. CONCLUSIONS:This review provides a series of practical recommendations to assist with managing the adverse effects of ADT.
journal_name
BJU Intjournal_title
BJU internationalauthors
Rhee H,Gunter JH,Heathcote P,Ho K,Stricker P,Corcoran NM,Nelson CCdoi
10.1111/bju.12964subject
Has Abstractpub_date
2015-04-01 00:00:00pages
3-13eissn
1464-4096issn
1464-410Xjournal_volume
115 Suppl 5pub_type
杂志文章,评审abstract:OBJECTIVE:To assess the outcome of different forms of urinary drainage, particularly for urinary tract infection (UTI), operative findings and patient preference, in patients treated for acute urinary retention (AUR). PATIENTS AND METHODS:A feasibility trial was conducted of men presenting with AUR; after a short peri...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02253.x
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:To investigate the high circumcision rate in South Korea and its rapid increase in the short period since its introduction. SUBJECTS AND METHODS:From January to December 2000, 5434 South Korean males (or their parents) aged 0-92 years were interviewed in detail about their circumcision status, their age at c...
journal_title:BJU international
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Category III chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most commonly diagnosed prostatitis syndrome. CP/CPPS is characterized by lower urinary tract symptoms (LUTS) of which pain (particularly perineal pain and pain on ejaculation) and dysfunctional voiding cause the greatest morbidity and poor...
journal_title:BJU international
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1464-410X.2008.07496.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and safety of ciprofloxacin 500 mg orally twice daily with pivampicillin 700 mg orally twice daily for 10 days in men with acute epididymitis and over 40 years of age. PATIENTS AND METHODS:The study comprised 172 men who entered a prospective, controlled, randomized, double-blind, tri...
journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1046/j.1464-410x.1999.00252.x
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To explore the meaning that men attach to their experiences of having lower urinary tract symptoms (LUTS) and to understand 'bother' in the context of those meanings. PATIENTS AND METHODS:Sixteen men with symptoms suggestive of LUTS and/or an enlarged prostate were recruited from the outpatient urology clini...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05720.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:To report the clinical experience with a second-generation of temporary implantable nitinol device (iTIND; Medi-Tate Ltd, Or-Akiva, Israel) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) after 1 year of follow-up. PATIENTS AND METHODS:In all, 81 patients w...
journal_title:BJU international
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/bju.14608
更新日期:2019-06-01 00:00:00
abstract:UNLABELLED:Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Erectile dysfunction is a recognized complication of radical prostatectomy. Androgen deprivation therapy adversely impacts sexual function. Our study shows that the preoperative use of androgen de...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2011.10728.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the functional and cosmetic results and patient satisfaction after triple incision plasty for phimosis in children. PATIENTS AND METHODS:The study included 197 boys who had a triple incision for phimosis (mean age 5.8 years, range 0.25-18). The indications for preputial surgery were recurrent bal...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04354.x
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between the International Prostate Symptom Score (IPSS) bother question (BQ) and a validated disease-specific quality-of-life questionnaire, the Benign Prostatic Hyperplasia (BPH) Impact Index (BPH-II), using the BPH Registry and Patient Survey database. PATIENTS AND METHODS:The B...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2008.07574.x
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To determine the risk of failure during drug development in castration-resistant prostate cancer (CRPC) and to identify factors that could improve outcomes. METHODS:We investigated CRPC by analysing compounds in phase I to phase III clinical trials between 1998 and April 2011. Drug development failures were...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.12309
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To quantify in absolute terms the potential benefit of regionalisation of care from low- to high-volume hospitals. PATIENTS AND METHODS:Patients with a primary diagnosis of bladder cancer treated with radical cystectomy (RC) were identified within the Nationwide Inpatient Sample, a retrospective observationa...
journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/bju.12288
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the clinical and video-urodynamic outcome in women with by stress urinary incontinence (SUI) treated with a bone-anchored pubovaginal sling. PATIENTS AND METHODS:The study included 70 women with SUI (as evaluated by a clinical examination, a voiding questionnaire, a short pad-test and video-urod...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410x.2003.04749.x
更新日期:2004-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14569
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To present our experience of cavernous nerve graft reconstruction, using an autologous nerve vein-guide technique, to restore potency. PATIENTS AND METHODS:Prostate cancers frequently require radical resection involving one or both cavernous nerves that usually results in erectile dysfunction; nerve grafting...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07068.x
更新日期:2007-11-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09507.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To describe the surgical technique and report early outcomes of transurethral assisted laparoendoscopic single-site (LESS) radical prostatectomy (RP) and LESS radical cystectomy (RC) in a single institution. MATERIALS AND METHODS:Between December 2014 and March 2016, a total of 114 LESS RPs and RCs were perf...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13965
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To report the experience of the last 4 years from a centre to which women with voiding difficulties and urinary retention were referred nationally, describing what investigations were helpful in making a diagnosis and the management strategies used. PATIENTS AND METHODS:Women with voiding difficulties and ur...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06009.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To analyse tumour extent as a predictor of cancer progression after radical prostatectomy (RP), using a multivariate Cox regression model, as several variables (e.g. Gleason grade and tumour stage) are well-established prognostic factors in prostate cancer but it is uncertain if the visual estimation of tumou...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05825.x
更新日期:2005-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.01901.x
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:To determine whether the use of nephron-sparing surgery (NSS) for treatment of stage 1 renal cell carcinoma (RCC) changed between 2009 and the end of 2013 in Australia. PATIENTS AND METHODS:All adult cases of RCC diagnosed in 2009, 2012 and 2013 were identified through the population-based Victorian Cancer ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.13889
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of the application of autologous myoblasts and fibroblasts for treating female stress urinary incontinence (SUI) after a follow-up of >/=1 year. PATIENTS AND METHODS:In all, 123 women with SUI (aged 36-84 years) were treated with transurethral ultrasonography-guided injectio...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07119.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To determine whether the rate of change in total serum prostate-specific antigen (PSA) levels accurately detects prostate cancer and to evaluate whether it adds any predictive value to a single measurement of serum PSA alone, in general practice settings. MATERIALS AND METHODS:A retrospective cohort of 219,3...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2012.11651.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To investigate the extent to which different types of bladder dysfunction can affect long-term renal function in boys with posterior urethral valves (PUV). PATIENTS AND METHODS:Renal and bladder function were retrospectively assessed in 59 boys with PUV (mean age 10 years, range 5-17). All patients included ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2002.02881.x
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:To determine whether the addition of ethanol to water for irrigation during transurethral resection of the prostate (TURP) and monitoring breath ethanol could be used to detect irrigant absorption and to limit free plasma haemoglobin in cases of absorption. PATIENTS AND METHODS:One hundred patients (46 in Pi...
journal_title:BJU international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1464-410x.2000.00979.x
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To increase the clinical usefulness of the actively deflectable flexible ureteroscope by making sequential changes in design and then using these prototypes clinically; and to develop a clinical series using the optimum prototype and contrast it with an extensive database of patients treated with the traditio...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410x.2004.04567.x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To define changes in the clinical pathway for open radical retropubic prostatectomy (RRP) and to determine their impact on patient care under the indirect influence of minimally invasive prostatectomy after implementing robotically assisted laparoscopic prostatectomy (RALP) at our institution and modifying th...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05993.x
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:To describe the most recent data from phase I and II clinical trials of stereotactic body radiation therapy (SBRT) using image-guided robotic radiosurgery, specifically the Cyberknife(®) (Accuracy Incorporated, Sunnyvale, CA, USA). To better determine thecurrent role of this type of radiosurgery in prostate ...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/bju.12000
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:To evaluate holmium:YAG laser vaporization of papillary tumours of the bladder, focusing on surgical technique, patients' satisfaction, complications and cost-effectiveness when using the technique under local anaesthesia as an outpatient procedure. PATIENTS AND METHODS:In all, 52 consecutive patients with ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.04882.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To compare directly the performance of the ADXBLADDER test with that of cytology in the detection of non-muscle-invasive bladder cancer (NMIBC) recurrences. BACKGROUND:ADXBLADDER is a urine test based on the detection of MCM5, a DNA licensing factor expressed in all cells capable of dividing. Expression is u...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.15194
更新日期:2020-08-03 00:00:00
abstract:OBJECTIVE:• To investigate the relationship between pretreatment testosterone levels and pathological specimen characteristics, by prospectively examining serum androgen concentrations in a well-studied cohort of patients who underwent radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS:• A ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09816.x
更新日期:2011-05-01 00:00:00