Abstract：
OBJECTIVE:To investigate the extent to which different types of bladder dysfunction can affect long-term renal function in boys with posterior urethral valves (PUV). PATIENTS AND METHODS:Renal and bladder function were retrospectively assessed in 59 boys with PUV (mean age 10 years, range 5-17). All patients included in the study had at least 4 years of follow-up and their bladder behaviour had been evaluated in at least two urodynamic studies. At the time of the study, of the 59 PUV boys, 37 had normal renal function and 22 had end-stage renal disease (ESRD). RESULTS:Of the 59 boys with PUV evaluated by urodynamic studies, 25 had normally behaving bladders (42%) and 34 had some type of bladder dysfunction (58%). Of the 22 in ESRD, 15 had abnormally behaving bladders (68%) and only seven had bladders with normal behaviour (32%). Of the 37 boys with normal renal function, 19 had dysfunctional bladders (51%) and 18 had normal bladders (49%). Instability was found in 17 of 19 boys with bladder dysfunction and normal renal function. On the contrary among 22 boys with ESRD, poor compliance was the most frequent urodynamic pattern (eight, 53%) while instability was only found in five. Overall, eight of nine boys with poorly compliant bladders, two of three with myogenic failure and a five of 22 with instability were in ESRD, and this situation occurred at an earlier age in patients with poorly compliant bladders. CONCLUSION:Bladder dysfunction should be considered as a prognostic factor in renal failure. Those with poor bladder compliance and myogenic failure have the worst outcome, while bladder instability was associated with the lowest incidence of renal failure.
journal_name
BJU Intjournal_title
BJU internationalauthors
Lopez Pereira P,Martinez Urrutia MJ,Espinosa L,Lobato R,Navarro M,Jaureguizar Edoi
10.1046/j.1464-410x.2002.02881.xkeywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
308-11issue
3eissn
1464-4096issn
1464-410Xpii
2881journal_volume
90pub_type
杂志文章abstract：OBJECTIVE:To determine whether bilateral electrical stimulation (BiES) of the transected pudendal sensory nerves could further enhance the voiding efficiency beyond that produced by unilateral electrical stimulation (UniES) of transected pudendal afferents in rats with urinary retention. MATERIALS AND METHODS:The effi...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2011.10526.x
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:To determine the value of gene-expression profiling as a predictor of the status of the regional nodes in patients with penile carcinoma. PATIENTS AND METHODS:Tumour samples of 56 patients with penile squamous cell carcinoma were analysed for the gene expression on 35 k oligoarrays; 32 were from patients wit...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.07697.x
更新日期：2008-08-01 00:00:00
abstract：:Laparoendoscopic single-site surgery (LESS) and natural orifice transluminal endoscopic surgery (NOTES™) are new approaches to minimally invasive surgery. A number of technical challenges need to be overcome and new developments of equipment are required before widespread acceptance of either modality occurs. In this ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2010.09665.x
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.07059.x
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To review the results of repairing a parastomal hernia after ileal conduit formation, using the lateral approach. PATIENTS AND METHODS:We retrospectively assessed 18 patients (9%) who developed a parastomal hernia, from 211 who had an ileal conduit created between 1982 and 2001; 15 had a surgical repair usin...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2004.05008.x
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.12865
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To describe a clinical subtype of urinary incontinence (UI) after a stroke, i.e. with impaired awareness of the need to void (IA-UI), and to compare it to urge UI after a stroke for the risk factors and medium-term outcome. PATIENTS AND METHODS:In a consecutive sample of 315 hospitalized stroke patients who ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2007.06754.x
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder. PATIENTS AND METHODS:The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was f...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06541.x
更新日期：2007-02-01 00:00:00
abstract：OBJECTIVE:To evaluate carbonic anhydrase IX (CAIX) expression as an independent prognostic marker for clear cell renal cell carcinoma (ccRCC). With recent smaller studies showing conflicting results, we aimed to update our initial analysis in 2007 with an additional 5-year follow-up. PATIENTS AND METHODS:We provided l...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.12075
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To assess, in a repeat audit of a regional lithotripsy service, whether changes implemented after a regional audit in 1994 (which showed disappointing results from shock wave lithotripsy, attributable to both poor patient selection and an inadequate fixed-site lithotripter) have had any effect. PATIENTS AND ...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1046/j.1464-410x.2002.02674.x
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVE:To develop a rat model of erectile dysfunction (ED) after cavernous nerve injury. MATERIALS AND METHODS:Given the great similarity between the anatomical structure of the cavernous nerve in rats and humans, 24 rats underwent dissections and the cavernous nerves were identified with the aid of an operating mi...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.07760.x
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To assess the changing distribution of stage in seminoma and nonseminomatous germ cell tumours (NSGCTs), as recent reports contained no detailed information on pT stage and vascular invasion, important factors in the decision for further treatment. PATIENTS AND METHODS:Histopathological reports from 1976 to ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2006.06424.x
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVES:To compare the prevalence of metabolic syndrome and the components of metabolic syndrome in men aged ≥50 years with and without clinical benign prostatic hyperplasia (BPH). SUBJECTS AND METHODS:This was a cross-sectional study using the UK Clinical Practice Research Datalink (CPRD). Men were selected from t...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.13334
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:•To determine the relationship between statin use and biochemical recurrence (BCR) following radical prostatectomy (RP). PATIENTS AND METHODS:•A retrospective analysis was performed on 3198 RP patients between 1990 and 2008. •Exclusion criteria were neo-adjuvant or adjuvant therapy, follow-up <2 years, and i...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2011.10159.x
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To evaluate a novel urine-collection device (UCD) that automatically collects a midstream urine (MSU) sample, and compare contamination rates to those of the conventional MSU sampling method, as the contamination of urine samples for microbiological analysis in women leads to diagnostic ambiguity and unnecess...
journal_title：BJU international
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1111/j.1464-410X.2005.05631.x
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To present the outcomes of cT3N0M0 prostate cancer after radical prostatectomy (RP) and determine the prognostic factors in biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS), cancer-specific survival (CSS) and overall survival (OS) after long-term follow-up of 10 years. ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2009.09054.x
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To present the long-term outcome of patients with locally advanced or metastatic prostate carcinoma treated by first-line antiandrogen monotherapy. PATIENTS AND METHODS:From 1983 to 1990, 41 patients with advanced prostate carcinoma were treated with flutamide monotherapy until progression or the appearance ...
journal_title：BJU international
pub_type： 临床试验,杂志文章
doi：10.1046/j.1464-410x.2003.04413.x
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:To evaluate the clinical significance of hypertension (HTN), neutropaenia and thrombocytopaenia as possible new biomarkers of sunitinib efficacy in non-trial patients with metastatic renal cell carcinoma (mRCC). PATIENTS AND METHODS:In all, 181 consecutive patients with mRCC were treated with sunitinib; 39 ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/bju.12940
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To describe metoidioplasty, a technique for creating a neophallus from an enlarged clitoris in female transsexuals, without needing the complex, multi-staged surgical construction of a large phallus, as this reconstruction is one of the most difficult in female transsexuals. PATIENTS AND METHODS:From Septemb...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410x.2003.04524.x
更新日期：2003-12-01 00:00:00
abstract：OBJECTIVE:To assess the effect of antimuscarinic treatment with tolterodine combined with behavioural modification as a first-line treatment, before invasive investigation, in children with non-neurogenic voiding dysfunction but no obvious anatomical or neurogenic cause. PATIENTS AND METHODS:The study comprised 44 chi...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05641.x
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVES:To determine if cells expressing prostate-specific antigen (PSA) can be detected in blood collected by a cell-saver during radical prostatectomy (RP) or in the peripheral blood after intraoperative autotransfusion (IAT). PATIENTS AND METHODS:In all, 112 men with clinical T1c-T2 prostate cancer undergoing RP...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05621.x
更新日期：2005-08-01 00:00:00
abstract：:To assess the evidence for the concept that the androgen receptor of prostate cancer (PCa) cells becomes saturated when testosterone values exceed castrate levels, so that testosterone administration in hypogonadal men with untreated PCa does not stimulate tumour growth. To propose basic criteria for administration of...
journal_title：BJU international
pub_type： 杂志文章,评审
doi：10.1111/j.1464-410X.2011.10193.x
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy and safety of ureteroscopy plus intracorporeal lithotripsy (ULT) with extracorporeal shock wave lithotripsy (ESWL) for treating distal ureteric calculi in childhood, as such stones are commonly treated by ESWL as the first option in adults but there is no agreement on the method of tre...
journal_title：BJU international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1464-410X.2005.05464.x
更新日期：2005-05-01 00:00:00
abstract：UNLABELLED:What's known on the subject? and What does the study add? Percutaneous renal cryoablation is a safe and effective treatment for patients with small renal masses, who are poor surgical candidates. Oncological outcomes from previous percutaneous ablation studies are difficult to interpret because of the large ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2012.11230.x
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:To determine whether the density of CD4(+) and CD8(+) T-lymphocytes in a transrectal ultrasonography (TRUS) biopsy of the prostate can be used to predict the progression of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH). PATIENTS AND METHODS:In total, 100 patients were randomly sel...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2010.09787.x
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To determine the effect of combined finasteride and flutamide therapy on haemoglobin and haematocrit values in men with advanced prostate cancer. PATIENTS AND METHODS:Nineteen men, previously untreated by hormone therapy, with histologically confirmed adenocarcinoma of the prostate and clinical evidence of a...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00844.x
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:To assess the sensitivity and specificity of blue-light cystoscopy (BLC) with hexaminolevulinate as an adjunct to white-light cystoscopy (WLC) vs WLC alone for the detection of non-muscle-invasive bladder cancer (NMIBC), in routine clinical practice in Spain. PATIENTS AND METHOD:An intra-patient comparative,...
journal_title：BJU international
pub_type： 杂志文章,多中心研究
doi：10.1111/bju.13020
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To characterize serial long-term histological changes in mesenchymal cells infiltrating a collagen-based matrix, as in a hollow organ with differentiated urothelial lining created intraperitoneally by grafting cultured urothelial cells, mesenchymal cells with smooth-muscle immunohistochemical characteristics ...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2005.05586.x
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the difference between radiographic size on computed tomography (CT) and the pathological size of renal tumours, in contemporary patients. PATIENTS AND METHODS:We retrospectively reviewed the records of 521 patients undergoing surgical resection of a renal mass between 2000 and 2007, who had tumo...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1111/j.1464-410X.2008.07941.x
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:To devise a procedure capable of curing complicated ureteric strictures and replacing segments of lost ureter, without the long-term infective complications of bowel interposition or the surgical magnitude of autotransplantation. PATIENTS AND METHODS:Four patients with complicated strictures and one with seg...
journal_title：BJU international
pub_type： 杂志文章
doi：10.1046/j.1464-410x.1999.00019.x
更新日期：1999-05-01 00:00:00
