Trends in the surgical management of stage 1 renal cell carcinoma: findings from a population-based study.


OBJECTIVES:To determine whether the use of nephron-sparing surgery (NSS) for treatment of stage 1 renal cell carcinoma (RCC) changed between 2009 and the end of 2013 in Australia. PATIENTS AND METHODS:All adult cases of RCC diagnosed in 2009, 2012 and 2013 were identified through the population-based Victorian Cancer Registry. For each identified patient, trained data-abstractors attended treating hospitals or clinician rooms to extract tumour and treatment data through medical record review. Multivariable logistic regression analyses were carried out to examine the significance of change in use of NSS over time, after adjusting for potential confounders. RESULTS:A total of 1 836 patients with RCC were identified. Of these, the proportion of cases with stage 1 tumours was 64% in 2009, 66% in 2012 and 69% in 2013. For T1a tumours, the proportion of patients residing in metropolitan areas receiving NSS increased from 43% in 2009 to 58% in 2012 (P < 0.05), and 69% in 2013 (P < 0.05). For patients residing in non-metropolitan areas, the proportion receiving NSS increased from 27% in 2009 to 49% in 2012, and 61% in 2013 (P < 0.01). Univariable logistic regression showed patients with moderate (odds ratio [OR] 0.57, 95% confidence interval [CI] 0.35-0.94) or severe comorbidities (OR 0.58, 95% CI 0.33-0.99), residing in non-metropolitan areas (OR 0.65, 95% CI 0.47-0.90), were less likely to be treated by NSS, while those attending high-volume hospitals (≥30 cases/year: OR 1.79, 95% CI 1.21-2.65) and those with higher socio-economic status (OR 1.45, 95% CI 1.02-2.07) were more likely to be treated by NSS. In multivariable analyses, patients with T1a tumours in 2012 (OR 2.00, 95% CI 1.34-2.97) and 2013 (OR 3.15, 95% CI 2.13-4.68) were more likely to be treated by NSS than those in 2009. For T1b tumours, use of NSS increased from 8% in 2009 to 20% in 2013 (P < 0.05). CONCLUSION:This population-based study of the management of T1 renal tumours in Australia found that the use of NSS increased over the period 2009 to 2013. Between 2009 and 2013 clinical practice for the treatment of small renal tumours in Australia has increasingly conformed to international guidelines.




BJU international


White V,Marco DJT,Bolton D,Davis ID,Jefford M,Hill D,Prince HM,Millar JL,Winship IM,Coory M,Giles GG




Has Abstract


2017-11-01 00:00:00








120 Suppl 3


  • Rates of prostate-specific antigen testing in general practice in England and Wales in asymptomatic and symptomatic patients: a cross-sectional study.

    abstract:OBJECTIVE:To assess the rate of prostate-specific antigen (PSA) testing for prostate cancer in general practice in asymptomatic and symptomatic patients. SUBJECTS AND METHODS:The cross-sectional study took place in England and Wales, was population-based and covered 469 159 men aged 45-84 years. Pathology data on PSA ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Melia J,Moss S,Johns L,Contributors in the participating laboratories.

    更新日期:2004-07-01 00:00:00

  • Stereotactic radiotherapy combined with immunotherapy or targeted therapy for metastatic renal cell carcinoma.

    abstract:OBJECTIVES:To evaluate the safety and efficacy of stereotactic radiotherapy (SRT) in patients with metastatic renal cell carcinoma (mRCC) concurrently receiving targeted therapy (TT) or immunotherapy. PATIENTS AND METHODS:Data on patients with mRCC were extracted from a retrospective international multicentre register...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Kroeze SGC,Fritz C,Schaule J,Siva S,Kahl KH,Sundahl N,Blanck O,Kaul D,Adebahr S,Verhoeff JJC,Skazikis G,Roeder F,Geier M,Eckert F,Guckenberger M

    更新日期:2020-10-28 00:00:00

  • Human DNA topoisomerase-IIalpha expression as a prognostic factor for transitional cell carcinoma of the urinary bladder.

    abstract:OBJECTIVE:To investigate the immunohistochemical expression of topoisomerase II-alpha (TII-alpha, a nuclear enzyme, the expression of which increases rapidly at the end of the S to G2/M phase and declines when mitosis ends) in bladder urothelial neoplasms (transitional cell carcinoma), and its correlation with grade, s...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Koren R,Kugel V,Dekel Y,Weissman Y,Livne PM,Gal R

    更新日期:2003-04-01 00:00:00

  • Calibration and dilatation with topical corticosteroid in the treatment of stenosis of neourethral meatus after hypospadias repair.

    abstract:OBJECTIVE:To assess the early disclosure and treatment of meatal stenosis after hypospadias repair, using calibration of the neourethral meatus at regular intervals to detect stenosis, and to assess the curative effects of dilatation with topical corticosteroids. PATIENTS AND METHODS:Between 2001 and 2003, 83 boys (me...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Radojicic ZI,Perovic SV,Stojanoski KD

    更新日期:2006-01-01 00:00:00

  • Long-term oncological outcomes of patients with paratesticular sarcoma.

    abstract:OBJECTIVES:To present long-term oncological outcomes of patients with paratesticular sarcoma treated by a multidisciplinary team. PATIENTS AND METHODS:Patients managed at the Princess Margaret Cancer Centre, between 1990 and 2012, were analysed. A sarcoma expert performed central pathology review. Kaplan-Meier graphs ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Goldberg H,Wong LM,Dickson B,Catton C,Yap SA,Alkasab T,Evans A,van der Kwast T,Jewett MAS,Hamilton RJ

    更新日期:2019-11-01 00:00:00

  • Secular trends in prostate cancer mortality, incidence and treatment: England and Wales, 1975-2004.

    abstract:OBJECTIVE:To aid the interpretation of the trends in prostate cancer mortality, which declined in the UK in the early 1990 s for unknown reasons, by investigating prostate cancer death rates, incidence and treatments in England and Wales in 1975-2004. METHODS:Join-point regression was used to assess secular trends in ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Hussain S,Gunnell D,Donovan J,McPhail S,Hamdy F,Neal D,Albertsen P,Verne J,Stephens P,Trotter C,Martin RM

    更新日期:2008-03-01 00:00:00

  • Prevalence of and risk factors for symptomatic urinary tract infection after endoscopic incision for the treatment of ureterocele in children.

    abstract:OBJECTIVE:To clarify the impact of endoscopic incision (EI) for ureterocele as an initial procedure, by performing a retrospective chart review, focusing on the prevalence of and risk factors for symptomatic urinary tract infection (UTI) after EI. MATERIALS AND METHODS:In the present study we included children with ur...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Moriya K,Nakamura M,Nishimura Y,Kanno Y,Kitta T,Kon M,Shinohara N

    更新日期:2017-09-01 00:00:00

  • The impact of androgen-deprivation therapy (ADT) on the risk of cardiovascular (CV) events in patients with non-metastatic prostate cancer: a population-based study.

    abstract:OBJECTIVE:To examine and quantify the contemporary association between androgen-deprivation therapy (ADT) and three separate endpoints: coronary artery disease (CAD), acute myocardial infarction (AMI), and sudden cardiac death (SCD), in a large USA contemporary cohort of patients with prostate cancer. PATIENTS AND MET...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Gandaglia G,Sun M,Popa I,Schiffmann J,Abdollah F,Trinh QD,Saad F,Graefen M,Briganti A,Montorsi F,Karakiewicz PI

    更新日期:2014-12-01 00:00:00

  • Improving the prognosis of patients after radical cystectomy. Part I: the role of lymph node dissection.

    abstract::The first two reviews are from the same unit in Germany and describe the well-known but still much discussed ways of improving the prognosis of patients undergoing cystectomy for bladder cancer. The authors review the roles of lymph node dissection and perioperative chemotherapy, and draw conclusions which will be of ...

    journal_title:BJU international

    pub_type: 杂志文章,评审


    authors: Suttmann H,Kamradt J,Lehmann J,Stöckle M

    更新日期:2007-12-01 00:00:00

  • European Randomised Study of Screening for Prostate Cancer (ERSPC) risk calculators significantly outperform the Prostate Cancer Prevention Trial (PCPT) 2.0 in the prediction of prostate cancer: a multi-institutional study.

    abstract:OBJECTIVE:To analyse the performance of the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) and two iterations of the European Randomised Study of Screening for Prostate Cancer (ERSPC) Risk Calculator, one of which incorporates prostate volume (ERSPC-RC) and the other of which incorporates prostate volume an...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Foley RW,Maweni RM,Gorman L,Murphy K,Lundon DJ,Durkan G,Power R,O'Brien F,O'Malley KJ,Galvin DJ,Brendan Murphy T,William Watson R

    更新日期:2016-11-01 00:00:00

  • Extended-spectrum β-lactamase in the rectal flora of patients undergoing transrectal prostate biopsy: a study of the prevalence in a major metropolitan hospital.

    abstract:OBJECTIVES:To determine the prevalence of extended-spectrum β-lactamase (ESBL) in patients undergoing transrectal prostate biopsy, to assess the incidence of postoperative sepsis, to correlate the development of sepsis with the presence of preoperative ESBL on rectal swabs, and to assess the adequacy of prophylactic an...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Sewell J,Chow K,De Sousa A,Sapre N,Norris B,Namdarian B,Sinickas V,Huang JG,Anderson P

    更新日期:2019-05-01 00:00:00

  • Society of Robotic Surgery review: recommendations regarding the risk of COVID-19 transmission during minimally invasive surgery.

    abstract:OBJECTIVES:To determine the risk of COVID-19 transmission during minimally invasive surgical (MIS) procedures METHODS: Surgical society statements regarding the risk of COVID transmission during MIS procedures were reviewed. In addition, the available literature on COVID-19 and other viral transmission in CO2 pneumoper...

    journal_title:BJU international

    pub_type: 杂志文章,评审


    authors: Porter J,Blau E,Gharagozloo F,Martino M,Cerfolio R,Duvvuri U,Caceres A,Badani K,Bhayani S,Collins J,Coelho R,Rocco B,Wiklund P,Nathan S,Parra-Davila E,Ortiz-Ortiz C,Maes K,Dasgupta P,Patel V

    更新日期:2020-08-01 00:00:00

  • National bias in citations in urology journals: parochialism or availability?

    abstract:OBJECTIVE:To determine any bias by authors of different nationalities in their citation rate of selected urological journals in papers published in the British Journal of Urology and the Journal of Urology. METHODS:Using a simple computer program and text files of accepted reports in the BJU, or those available on CD-...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Grange RI

    更新日期:1999-10-01 00:00:00

  • Association of hospital volume with conditional 90-day mortality after cystectomy: an analysis of the National Cancer Data Base.

    abstract:OBJECTIVE:To examine the association of hospital volume and 90-day mortality after cystectomy, conditional on survival for 30 days. PATIENTS AND METHODS:The National Cancer Data Base was used to evaluate 30- and 90-day mortality for 35,055 patients who underwent cystectomy for bladder cancer at one of 1118 hospitals. ...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究


    authors: Nielsen ME,Mallin K,Weaver MA,Palis B,Stewart A,Winchester DP,Milowsky MI

    更新日期:2014-07-01 00:00:00

  • Surveillance for bladder cancer: the management of 4.8 million people. South-west Urologists.

    abstract:OBJECTIVE:To document the workload of bladder cancer surveillance on the British urologist. Methods Thirty-one consultant urologists serving a population of 4.8 million were sent postal questionnaires eliciting their views on the management of superficial bladder cancer. The number, type and outcome of cystoscopies per...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Wright MP,Jones DJ

    更新日期:2000-03-01 00:00:00

  • Urinary retention in women: its causes and management.

    abstract:OBJECTIVE:To report the experience of the last 4 years from a centre to which women with voiding difficulties and urinary retention were referred nationally, describing what investigations were helpful in making a diagnosis and the management strategies used. PATIENTS AND METHODS:Women with voiding difficulties and ur...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Kavia RB,Datta SN,Dasgupta R,Elneil S,Fowler CJ

    更新日期:2006-02-01 00:00:00

  • Thrombotic risk factors associated with transurethral prostatectomy.

    abstract:OBJECTIVE:To ascertain the potential thrombotic risk associated with transurethral prostatectomy (TURP). PATIENTS AND METHODS:The changes in coagulation variables were assessed in a prospective study of 40 patients undergoing TURP. RESULTS:There was a significant increase in thrombin-antithrombin complexes 6 h after ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Bell CR,Murdock PJ,Pasi KJ,Morgan RJ

    更新日期:1999-06-01 00:00:00

  • Testicular-sparing surgery: a reasonable option in selected patients with testicular lesions.

    abstract:OBJECTIVE:To describe our experience of inguinal exploration in patients who had a reasonable chance of having a benign testicular lesion. PATIENTS AND METHODS:From 1995 to 2002, 11 patients (mean age 43 years, range 27-63) with testicular masses that were suspected to be benign underwent inguinal exploration. RESULT...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Passarella M,Usta MF,Bivalacqua TJ,Hellstrom WJ,Davis R

    更新日期:2003-03-01 00:00:00

  • Clomiphene citrate is safe and effective for long-term management of hypogonadism.

    abstract:OBJECTIVE:To assess the efficacy and safety of long-term clomiphene citrate (CC) therapy in symptomatic patients with hypogonadism (HG). PATIENTS AND METHODS:Serum T, oestradiol and luteinizing hormone (LH) were measured in patients who were treated with CC for over 12 months. Additionally, bone densitometry (BD) resu...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Moskovic DJ,Katz DJ,Akhavan A,Park K,Mulhall JP

    更新日期:2012-11-01 00:00:00

  • Does working channel position influence the effectiveness of flexible ureteroscopy? Results from an in vitro study.

    abstract:OBJECTIVE:To evaluate whether the position of the working channel affects the effectiveness of flexible ureteroscopy. MATERIALS AND METHODS:We compared the ureteroscopes Flex-X2S and Flex-XC (working channel at the 9 and 3 o'clock positions, respectively) in eight cavities of a K-Box model, simulating the distribution...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Villa L,Ventimiglia E,Proietti S,Giusti G,Briganti A,Salonia A,Montorsi F,Doizi S,Traxer O

    更新日期:2020-03-01 00:00:00

  • Prevalence of ciprofloxacin-resistant Enterobacteriaceae in the intestinal flora of patients undergoing transrectal prostate biopsy in Norwich, UK.

    abstract:OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Hanna MY,Tremlett C,Josan G,Eltom A,Mills R,Rochester M,Livermore DM

    更新日期:2015-07-01 00:00:00

  • How long is urinary cytology abnormal after flexible cystoscopy?

    abstract:OBJECTIVE:To examine the urinary cytological changes caused by flexible cystoscopy and provide clinical guidelines for a reliable time interval for urinary cytological examination after flexible cystoscopy. PATIENTS AND METHODS:Forty-eight patients attending for flexible cystoscopy were recruited into the study. Each ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: McVey RJ,Persad RV,Brown SC,Robinson E,Payne SR

    更新日期:2004-09-01 00:00:00

  • Autonomic nerve involvement and venous leakage in diabetic men with impotence.

    abstract:OBJECTIVE:To determine the neurophysiological and vascular factors in diabetic impotence, particularly the role of autonomic neuropathy on venous leakage and erectile impotence. PATIENTS AND METHODS:Thirty-four diabetic men with impotence were investigated using various neurophysiological and radiological methods. The...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Colakoglu Z,Kutluay E,Ertekin C,Altay B,Killi R,Alkis A

    更新日期:1999-03-01 00:00:00

  • Long-term third-party assessment of results after continent cutaneous diversion with Lundiana pouch.

    abstract:OBJECTIVES:To investigate the long-term functional outcomes and complications after continent cutaneous diversion with the Lundiana pouch. PATIENTS AND METHODS:Complications, re-operations, renal function, and continence were ascertained from patient charts. Outcome variables were validated by a second and independent...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究


    authors: Liedberg F,Gudjonsson S,Xu A,Bendahl PO,Davidsson T,Månsson W

    更新日期:2017-10-01 00:00:00

  • Detection of urinary leakage after radical retropubic prostatectomy by contrast enhanced ultrasound - do we still need conventional retrograde cystography?

    abstract:INTRODUCTION:To prospectively evaluate the accuracy of transvesical contrast-enhanced ultrasound (CEUS) as an alternative method for the detection of anastomotic leakage after radical retropubic prostatectomy (RRP) in comparison with the current standard method of conventional retrograde cystography (CG). PATIENTS AND...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Schoeppler GM,Buchner A,Zaak D,Khoder W,Staehler M,Stief CG,Reiser MF,Clevert DA

    更新日期:2010-12-01 00:00:00

  • Three-dimensional virtual imaging of renal tumours: a new tool to improve the accuracy of nephrometry scores.

    abstract:OBJECTIVES:To apply the standard PADUA and RENAL nephrometry score variables to three-dimensional (3D) virtual models (VMs) produced from standard bi-dimensional imaging, thereby creating three-dimensional (3D)-based (PADUA and RENAL) nephrometry scores/categories for the reclassification of the surgical complexity of ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Porpiglia F,Amparore D,Checcucci E,Manfredi M,Stura I,Migliaretti G,Autorino R,Ficarra V,Fiori C

    更新日期:2019-12-01 00:00:00

  • Multi-centre, prospective evaluation of the Seldinger technique for difficult male urethral catheter insertions by non-urology trained doctors.

    abstract:OBJECTIVE:To evaluate the safety and effectiveness of the Seldinger technique by non-urology trained (NUT) doctors for difficult male indwelling urinary catheter (IDC) insertions. PATIENTS AND METHODS:In all, 115 patients and 57 participating NUT doctors were recruited by the urologist or urology registrar, when conta...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究


    authors: Yuminaga Y,Kam J,Louie-Johnsun M

    更新日期:2017-11-01 00:00:00

  • Lower urinary tract symptoms and related help-seeking behaviour in South Asian men living in the UK.

    abstract:OBJECTIVE:To describe the pattern and prevalence of lower urinary tract symptoms (LUTS) and related help-seeking behaviour in men of South Asian origin living in the UK, and to compare this to the white population. SUBJECTS AND METHODS:Data were obtained as part of the Leicestershire MRC Incontinence Study. Community-...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Taylor J,McGrother CW,Harrison SC,Assassa PR,Leicestershire MRC Incontinence Study Team.

    更新日期:2006-09-01 00:00:00

  • Second-generation of temporary implantable nitinol device for the relief of lower urinary tract symptoms due to benign prostatic hyperplasia: results of a prospective, multicentre study at 1 year of follow-up.

    abstract:OBJECTIVES:To report the clinical experience with a second-generation of temporary implantable nitinol device (iTIND; Medi-Tate Ltd, Or-Akiva, Israel) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) after 1 year of follow-up. PATIENTS AND METHODS:In all, 81 patients w...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Porpiglia F,Fiori C,Amparore D,Kadner G,Manit A,Valerio M,Nicolaas L,Ho BSH,Alonso S,Schulman C,Barber N

    更新日期:2019-06-01 00:00:00

  • The association of endothelial nitric oxide synthase (eNOS) G894T gene polymorphism with responsiveness to a selective α1 -blocker in men with benign prostatic hyperplasia related lower urinary tract symptoms.

    abstract:OBJECTIVE:To prospectively investigate the association of endothelial nitric oxide synthase (eNOS) G894T gene polymorphism with responsiveness to a selective α1 -blocker in men with benign prostatic hyperplasia related lower urinary tract symptoms (BPH/LUTS), as nitric oxide has recently gained increasing recognition a...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Lee YC,Juan YS,Liu CC,Bao BY,Wang CJ,Wu WJ,Huang CN,Huang SP

    更新日期:2016-08-01 00:00:00