The impact of training on service provision in laparoscopic radical prostatectomy.

Abstract:

OBJECTIVE:To address concerns about the impact of training on patient outcomes during the 'learning curve' for laparoscopic radical prostatectomy (LRP), we compare the results of our patients undergoing LRP with and without trainees performing a substantial proportion of the cases. PATIENTS AND METHODS:In all, 771 consecutive cases of LRP were performed or supervised by one surgeon during a 7.5-year period, of which 114 (15%) were training cases. A five-port transperitoneal technique was used in the first 111 patients and an extraperitoneal approach in the remaining 660. Patient, operative and oncological outcome variables were compared using an independent samples t-test if continuous or with Fisher's exact test for rates. RESULTS:There were no differences in preoperative patient or cancer characteristics with the exception of body mass index (BMI) which was lower in the training cases (medians 25 and 26 kg/m(2), P = 0.02) and patient age which was higher (medians 64 and 62 years, P < 0.001). Operative time, which was longer in training cases (medians 200 and 175 min, P < 0.001) was the only significantly different operative variable between the groups. There were no statistically significant differences in postoperative (duration of catheterization, hospitalization time, complication rates, biochemical recurrence and pad-free rates at 1 year) or pathological (gland weight, positive surgical margin rate) outcomes between the groups. As Fellows did not perform the posterior or apical dissection steps in nerve-sparing cases, no evaluation of potency outcomes is included. CONCLUSIONS:Training cases took a median of 25 min longer to complete than non-training cases. However, other perioperative measures, complications rates and cancer outcomes were similar. Adequately supervised training in LRP does indeed take additional time but is essential for the dissemination of surgical skills and preservation of acceptable outcomes.

journal_name

BJU Int

journal_title

BJU international

authors

Neill MG,Chabert CC,Merrilees DA,Eden CG

doi

10.1111/j.1464-410X.2008.08262.x

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

1231-4; discussion 1234-5

issue

9

eissn

1464-4096

issn

1464-410X

pii

BJU8262

journal_volume

103

pub_type

杂志文章
  • The utility of lactate dehydrogenase in the follow-up of testicular germ cell tumours.

    abstract:OBJECTIVE:To evaluate the utility of lactate dehydrogenase (LDH), a tumour marker that is frequently elevated at diagnosis and relapse of testicular germ cell tumours (TGCTs), in the follow-up of TGCTs for detecting tumour relapse, as it has role as a prognostic factor but its role in follow-up is less certain. PATIEN...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2007.06905.x

    authors: Venkitaraman R,Johnson B,Huddart RA,Parker CC,Horwich A,Dearnaley DP

    更新日期:2007-07-01 00:00:00

  • Predictive factors of ultrasonographic involution of prenatally detected multicystic dysplastic kidney.

    abstract:OBJECTIVE:To evaluate possible predictive factors of involution on ultrasonography (US) or disappearance of a prenatally detected multicystic dysplastic kidney (MCDK). PATIENTS AND METHODS:Forty-five children with unilateral MCDK detected by prenatal ultrasonography between 1989 and 2002 were analysed. All patients ex...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05418.x

    authors: Rabelo EA,Oliveira EA,Silva GS,Pezzuti IL,Tatsuo ES

    更新日期:2005-04-01 00:00:00

  • Clinical efficacy of collagenase Clostridium histolyticum in the treatment of Peyronie's disease by subgroup: results from two large, double-blind, randomized, placebo-controlled, phase III studies.

    abstract:OBJECTIVES:To examine the efficacy of intralesional collagenase Clostridium histolyticum (CCH) in defined subgroups of patients with Peyronie's disease (PD). PATIENTS AND METHODS:The efficacy of CCH compared with placebo, assessed from baseline to week 52, was examined in subgroups of participants from the Investigati...

    journal_title:BJU international

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/bju.13096

    authors: Lipshultz LI,Goldstein I,Seftel AD,Kaufman GJ,Smith TM,Tursi JP,Burnett AL

    更新日期:2015-10-01 00:00:00

  • Porcine small intestinal submucosa as a percutaneous mid-urethral sling: 2-year results.

    abstract:OBJECTIVE:To report the 2-year follow-up results on patients treated with a novel minimally invasive outpatient procedure for placing a mid-urethral sling, using porcine small intestinal submucosa (SIS). PATIENTS AND METHODS:Thirty-four women with urodynamic evidence of stress urinary incontinence (SUI, 19) or of SUI ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05576.x

    authors: Jones JS,Rackley RR,Berglund R,Abdelmalak JB,DeOrco G,Vasavada SP

    更新日期:2005-07-01 00:00:00

  • Biopsy-confirmed de novo renal cell carcinoma (RCC) in renal grafts: a single-centre management experience in a 2396 recipient cohort.

    abstract:OBJECTIVE:To study the natural history of renal cell carcinoma (RCC) development in renal grafts and their management. PATIENTS AND METHODS:We report a single-centre series of de novo RCC in allografts from a cohort of 2396 consecutive renal transplant recipients. RESULTS:In all, 17 RCCs were detected in 12 patients,...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2011.10315.x

    authors: Ploussard G,Chambade D,Meria P,Gaudez F,Tariel E,Verine J,De Bazelaire C,Peraldi MN,Glotz D,Desgrandchamps F,Mongiat-Artus P

    更新日期:2012-01-01 00:00:00

  • Does information provided to men before a urodynamic study affect their expectation of pain?

    abstract:OBJECTIVE:To evaluate the effect of a routine explanation provided to men on their expectation of pain associated with a urodynamic study (UDS). PATIENTS AND METHODS:The purpose of UDS is to reproduce patient's symptoms during the urine storage and voiding phases, and thus understand the causes of the patient's sympto...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2005.05828.x

    authors: Greenstein A,Bar-Yosef Y,Chen J,Matzkin H

    更新日期:2005-12-01 00:00:00

  • Percutaneous cryoablation of renal masses: Washington University experience of treating 129 tumours.

    abstract:UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: For patients who are unfit for extirpative surgery, percutaneous cryoablation (PCA) presents a minimally-invasive alternative for the treatment of renal masses. PCA has been demonstrated to be safe, with complication rates <10% being reported consist...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.11432.x

    authors: Kim EH,Tanagho YS,Bhayani SB,Saad NE,Benway BM,Figenshau RS

    更新日期:2013-05-01 00:00:00

  • Stratification of patients with intermediate-risk prostate cancer.

    abstract:OBJECTIVE:To identify an appropriate risk stratification system for intermediate-risk prostate cancer (PCa). PATIENTS AND METHODS:We reviewed the data on 1559 patients who were treated with radical prostatectomy (RP) at our institution between 2005 and 2013 and classified them according to National Comprehensive Cance...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12703

    authors: Jung JW,Lee JK,Hong SK,Byun SS,Lee SE

    更新日期:2015-06-01 00:00:00

  • Cost-effectiveness analysis of treatments for phimosis: a comparison of surgical and medicinal approaches and their economic effect.

    abstract:OBJECTIVE:To compare the cost-effectiveness of surgery and topical steroids as treatments for phimosis (defined as a clinically verifiable, pathological, cicatricial stenosis of the prepuce) and to evaluate the financial basis of these treatments. METHODS:Data on treatment using topical steroids was obtained from publ...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1046/j.1464-410x.2001.02033.x

    authors: Berdeu D,Sauze L,Ha-Vinh P,Blum-Boisgard C

    更新日期:2001-02-01 00:00:00

  • Antibiotics and observation have a similar impact on asymptomatic patients with a raised PSA.

    abstract:OBJECTIVES:• To compare the influence of a 4-week course of empirical antimicrobial therapy or observation on the prostate-specific antigen (PSA) levels of asymptomatic patients with a raised baseline PSA. • To identify whether a decrease in PSA can predict the risk of prostate cancer (PCa) detection on prostate biopsy...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09948.x

    authors: Heldwein FL,Teloken PE,Hartmann AA,Rhoden EL,Teloken C

    更新日期:2011-05-01 00:00:00

  • Indications for and complications of pelvic lymph node dissection in prostate cancer: accuracy of available nomograms for the prediction of lymph node invasion.

    abstract:OBJECTIVES:To externally validate the currently available nomograms for predicting lymph node invasion (LNI) in patients with prostate cancer (PCa) and to assess the potential risk of complications of extended pelvic lymph node dissection (ePLND) when using the recommended threshold. METHODS:A total of 14 921 patients...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.15220

    authors: Oderda M,Diamand R,Albisinni S,Calleris G,Carbone A,Falcone M,Fiard G,Gandaglia G,Marquis A,Marra G,Parola C,Pastore A,Peltier A,Ploussard G,Roumeguère T,Sanchez-Salas R,Simone G,Smelzo S,Witt JH,Gontero P

    更新日期:2020-09-01 00:00:00

  • A phase II study of the efficacy and safety of AMG 102 in patients with metastatic renal cell carcinoma.

    abstract:OBJECTIVE:• To evaluate the efficacy and safety of single-agent AMG 102, an investigational, fully human monoclonal antibody to hepatocyte growth factor/scatter factor (HGF/SF), in renal cell carcinoma (RCC). PATIENTS AND METHODS:• This open-label phase II study included patients ≥ 18 years old with histologically con...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09947.x

    authors: Schöffski P,Garcia JA,Stadler WM,Gil T,Jonasch E,Tagawa ST,Smitt M,Yang X,Oliner KS,Anderson A,Zhu M,Kabbinavar F

    更新日期:2011-09-01 00:00:00

  • Novel anticoagulants and antiplatelet agents; a guide for the urologist.

    abstract::Novel oral anti-coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing p...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/bju.13131

    authors: Ellis G,John Camm A,Datta SN

    更新日期:2015-11-01 00:00:00

  • Is extracorporeal shock wave lithotripsy the preferred treatment option for elderly patients with urinary stone? A multivariate analysis of the effect of patient age on treatment outcome.

    abstract:OBJECTIVES:To investigate the effect of patient age on the stone-free rate (SFR) in patients with urinary calculi treated by extracorporeal shockwave lithotripsy (ESWL). PATIENTS AND METHODS:In all, 2192 solitary radio-opaque urinary stones of 5-15 mm were identified in adult patients receiving primary ESWL. Patients ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2007.06909.x

    authors: Ng CF,Wong A,Tolley D

    更新日期:2007-08-01 00:00:00

  • Improved prognosis of patients with intermediate- and poor-risk nonseminomatous germ cell tumours by optimizing combined treatment.

    abstract:OBJECTIVE:To assess whether the optimal use of combined treatment with chemotherapy and appropriately timed surgical intervention by a specialized team might improve the outcome for patients with poor- and intermediate-prognosis (International Germ Cell Consensus Classification, IGCCC) nonseminomatous germ cell tumours...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2003.04261.x

    authors: Pentheroudakis G,De Bono JS,Kaye SB,Simpson A,Paul J,Brown I,Pamenter B,Kirk A,Vasey P,Raby N,Kirk D

    更新日期:2003-07-01 00:00:00

  • Posterior tibial nerve stimulation in patients with intractable interstitial cystitis.

    abstract:OBJECTIVE:To evaluate the efficacy of intermittent percutaneous posterior tibial nerve stimulation (PPTNS) in patients with refractory interstitial cystitis. PATIENTS AND METHODS:One man and 13 women (mean age 58.3 years) with suprapubic or perineal pain were enrolled in a prospective open study, in which they had 10 ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2004.04909.x

    authors: Zhao J,Nordling J

    更新日期:2004-07-01 00:00:00

  • Quality of life after brachytherapy or bilateral nerve-sparing robot-assisted radical prostatectomy for prostate cancer: a prospective cohort.

    abstract:OBJECTIVE:To provide comparative data on quality of life (QoL) after prostate cancer treatment to help patients make an informed decision regarding their choice of treatment. METHODS:Patients with pathologically proven, non-metastatic, T1-T3bN0 prostate cancer were included in this prospective non-randomized study if ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.14021

    authors: Blanchard P,Davis JW,Frank SJ,Kim J,Pettaway CA,Pugh TJ,Pisters LL,Ward JF,Choi S,Chapin BF,Hoffman K,Navai N,Achim M,McGuire SE,Matin SF,Nguyen Q,Mahmood U,Graber WJ,Chen HC,Wang X,Kuban DA

    更新日期:2018-04-01 00:00:00

  • Reduced estimated glomerular filtration rate (eGFR

    abstract:OBJECTIVE:To evaluate if moderate chronic kidney disease [CKD; estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2 ] is associated with high rates of non-muscle-invasive bladder cancer (NMIBC) recurrence or progression. PATIENTS AND METHODS:A multi-institutional database identified patients with serum creat...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.13904

    authors: Blute ML Jr,Kucherov V,Rushmer TJ,Damodaran S,Shi F,Abel EJ,Jarrard DF,Richards KA,Messing EM,Downs TM

    更新日期:2017-09-01 00:00:00

  • Pharmacological preconditioning of ATP-sensitive potassium channel openers on acute urinary retention-induced bladder dysfunction in the rat.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? Acute urinary retention (AUR) and catheterization for AUR (AURC) or drainage of the urine is a well established cause of bladder dysfunction. Previously, we reported that the induction of AURC significantly reduced contractile responses to both carbac...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.10965.x

    authors: Ohmasa F,Saito M,Oiwa H,Tsounapi P,Shomori K,Kitatani K,Dimitriadis F,Kinoshita Y,Satoh K

    更新日期:2012-09-01 00:00:00

  • Heat-induced apoptosis in human prostatic stromal cells.

    abstract:OBJECTIVE:To determine whether heat, used in transurethral microwave thermotherapy (TUMT) for benign prostatic hyperplasia and which causes necrotic lesions within the adenoma, induces apoptosis in benign human prostatic stromal cells. Materials and methods Prostatic stromal cells were cultured from benign human prosta...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2000.00473.x

    authors: Brehmer M,Svensson I

    更新日期:2000-03-01 00:00:00

  • Beyond the cluster: methodological and clinical implications in the Boston Area Community Health survey and EPIC studies.

    abstract:OBJECTIVE:To test the replicability and robustness of findings about urological symptoms in men and women, classified using an objective statistical method, cluster analysis, by planned sensitivity analyses conducted within and across two large, epidemiological studies of lower urinary tract symptoms. METHODS:Sensitiv...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2008.07653.x

    authors: Rosen RC,Coyne KS,Henry D,Link CL,Cinar A,Aiyer LP,Mollon P,Kaplan SA,Roehrborn CG,Thompson C

    更新日期:2008-05-01 00:00:00

  • The control of haemolysis during transurethral resection of the prostate when water is used for irrigation: monitoring absorption by the ethanol method.

    abstract:OBJECTIVE:To determine whether the addition of ethanol to water for irrigation during transurethral resection of the prostate (TURP) and monitoring breath ethanol could be used to detect irrigant absorption and to limit free plasma haemoglobin in cases of absorption. PATIENTS AND METHODS:One hundred patients (46 in Pi...

    journal_title:BJU international

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1464-410x.2000.00979.x

    authors: Hultén JO,Tran VT,Pettersson G

    更新日期:2000-12-01 00:00:00

  • Clinical trial risk in castration-resistant prostate cancer: immunotherapies show promise.

    abstract:OBJECTIVES:To determine the risk of failure during drug development in castration-resistant prostate cancer (CRPC) and to identify factors that could improve outcomes. METHODS:We investigated CRPC by analysing compounds in phase I to phase III clinical trials between 1998 and April 2011. Drug development failures were...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12309

    authors: Tenuta A,Klotz L,Parker JL

    更新日期:2014-05-01 00:00:00

  • Gleason 7 prostate cancer treated with low-dose-rate brachytherapy: lack of impact of primary Gleason pattern on biochemical failure.

    abstract:UNLABELLED:What's known on the subject? and What does the study add? There appears to be a clear difference in cancer control outcomes for patients with Gleason scores of 3+4 and those with scores of 4+3 after radical prostatectomy. It has been documented that patients with Gleason 4+3 prostate cancer have higher incid...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2012.11057.x

    authors: Stock RG,Berkowitz J,Blacksburg SR,Stone NN

    更新日期:2012-11-01 00:00:00

  • Zoledronic acid is effective in preventing and delaying skeletal events in patients with bone metastases secondary to genitourinary cancers.

    abstract::Patients with metastatic bone disease often have severe bone pain and debilitating skeletal complications. Zoledronic acid is the only bisphosphonate shown to be safe and effective in reducing skeletal-related events (SREs), including pathological fractures, spinal cord compression, and radiation or surgery to bone in...

    journal_title:BJU international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1464-410X.2005.05740.x

    authors: Saad F,Lipton A

    更新日期:2005-11-01 00:00:00

  • Correlation between major histocompatibility complex class I molecules and CD8+ T lymphocytes in prostate, and quantification of CD8 and interferon-gamma mRNA in prostate tissue specimens.

    abstract:OBJECTIVE:To investigate the immunology of host-tumour interaction, critical for the development of immunotherapy against cancers, by assessing the major histocompatibility complex (MHC) class I expression in both benign and malignant prostate disease, and the relationship between their expression and degree of tumour-...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1046/j.1464-410x.2002.02993.x

    authors: Naoe M,Marumoto Y,Ishizaki R,Ogawa Y,Nakagami Y,Yoshida H

    更新日期:2002-11-01 00:00:00

  • Identification of novel oncogenic events occurring early in prostate carcinogenesis using purified autologous malignant and non-malignant prostate epithelial cells.

    abstract:OBJECTIVE:To interrogate enriched prostate cancer cells and autologous non-malignant prostate epithelial cells from men with localized prostate cancer, in order to identify early oncogenic pathways. PATIENTS AND METHODS:We collected malignant and matched non-malignant prostatectomy samples from men with adenocarcinoma...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.14695

    authors: Sluka P,Pezaro C,Wardan H,Sengupta S,Davis ID

    更新日期:2019-05-01 00:00:00

  • A new one-layer epididymovasostomy technique.

    abstract:OBJECTIVES:To describe and evaluate the outcomes of a new epididymovasostomy technique. PATIENTS AND METHODS:Nine patients with obstructive azoospermia were treated at the Minia University Hospital using a new microsurgical bilateral epididymovasostomy technique. The technique involved the opening of a small window in...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/bju.12839

    authors: Hussein A

    更新日期:2015-04-01 00:00:00

  • Human immunodeficiency virus-associated prostate cancer: clinicopathological findings and outcome in a multi-institutional study.

    abstract:OBJECTIVE:To characterize the clinicopathological findings and the outcome of human immunodeficiency virus (HIV)-infected patients diagnosed and treated for prostate carcinoma, as HIV-positive men being treated with highly active antiretroviral therapy (HAART) are living longer and thus are more likely to develop cance...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1464-410X.2008.07474.x

    authors: Pantanowitz L,Bohac G,Cooley TP,Aboulafia D,Dezube BJ

    更新日期:2008-06-01 00:00:00

  • Low pretreatment total testosterone (< 3 ng/mL) predicts extraprostatic disease in prostatectomy specimens from patients with preoperative localized prostate cancer.

    abstract:OBJECTIVE:• To investigate the relationship between pretreatment testosterone levels and pathological specimen characteristics, by prospectively examining serum androgen concentrations in a well-studied cohort of patients who underwent radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS:• A ...

    journal_title:BJU international

    pub_type: 杂志文章

    doi:10.1111/j.1464-410X.2010.09816.x

    authors: Xylinas E,Ploussard G,Durand X,Fabre A,Salomon L,Allory Y,Vordos D,Hoznek A,Abbou CC,de la Taille A

    更新日期:2011-05-01 00:00:00