Polymorphism in the gene encoding toll-like receptor 10 may be associated with asthma after bronchiolitis.

abstract：:Statins are a class of oral drugs that are widely used for treatment of hypercholesterolemia. Recent clinical data suggest that chronic use of these drugs increases the frequency of new onset diabetes. Studies to define the risks of statin-induced diabetes and its underlying mechanisms are clearly necessary. We explor...

journal_title：Scientific reports

authors： Kain V,Kapadia B,Misra P,Saxena U

更新日期：2015-09-08 00:00:00

abstract：:Previous analyses of the Atlantic cod genome showed unique combinations of lacking and expanded number of genes for the immune system. The present study examined lysozyme activity, lysozyme gene distribution and expression in cod. Enzymatic assays employing specific bacterial lysozyme inhibitors provided evidence for ...

journal_title：Scientific reports

authors： Seppola M,Bakkemo KR,Mikkelsen H,Myrnes B,Helland R,Irwin DM,Nilsen IW

更新日期：2016-06-21 00:00:00

abstract：:In this paper, the periodic double-layer graphene ribbon arrays placed near a metallic ground plate coated by a dielectric layer are proposed and analyzed by the coupled-mode theory (CMT) to predict the perfect absorption response in the mid-infrared region. Numerical simulations of the finite-difference time-domain (...

journal_title：Scientific reports

authors： Li H,Wang L,Zhai X

更新日期：2016-11-15 00:00:00

abstract：:The Pannexin 1 (Panx1) ion and metabolite channel is expressed in a wide variety of cells where it regulates a number of cell behaviours including proliferation and differentiation. Panx1 is expressed on the cell surface as well as intracellular membranes. Previous work suggests that a region within the proximal Panx1...

journal_title：Scientific reports

authors： Epp AL,Ebert SN,Sanchez-Arias JC,Wicki-Stordeur LE,Boyce AKJ,Swayne LA

更新日期：2019-07-05 00:00:00

abstract：:A larger amount of sequence data in private and public databases produced by next-generation sequencing put new challenges due to limitation associated with the alignment-based method for sequence comparison. So, there is a high need for faster sequence analysis algorithms. In this study, we developed an alignment-fre...

journal_title：Scientific reports

authors： Saw AK,Raj G,Das M,Talukdar NC,Tripathy BC,Nandi S

更新日期：2019-03-06 00:00:00

abstract：:Age-related macular degeneration (AMD) is a chronic degenerative disease of the retina. Recent reports have highlighted the potential role of mucosal surface microbes in the pathogenesis of AMD. In this case-control study, the composition of the nasal and oral microbiota in newly diagnosed neovascular age-related macu...

journal_title：Scientific reports

authors： Rullo J,Far PM,Quinn M,Sharma N,Bae S,Irrcher I,Sharma S

更新日期：2020-03-02 00:00:00

abstract：:The current study aimed to evaluate the efficacy of linked color imaging (LCI) in improving the visibility of superficial non-ampullary duodenal epithelial tumors (SNADETs). We prospectively evaluated 44 consecutive patients diagnosed with SNADETs. Three trainees and three experts assessed the visibility scores of whi...

journal_title：Scientific reports

authors： Okimoto K,Maruoka D,Matsumura T,Tokunaga M,Kaneko T,Oura H,Akizue N,Ohta Y,Saito K,Arai M,Kato J,Kato N

更新日期：2020-11-26 00:00:00

abstract：:Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids (FFA) are essentially unknown, we determined the lipidomic expression profile after burn in correlation to cl...

journal_title：Scientific reports

authors： Qi P,Abdullahi A,Stanojcic M,Patsouris D,Jeschke MG

更新日期：2016-12-16 00:00:00

abstract：:Recently, extracorporeal shock wave therapy (ESWT) has been shown to be a novel therapy for carpal tunnel syndrome (CTS). However, previous studies did not examine the diverse effects of different-session ESWT for different-grades CTS. Thus, we conducted a randomized, single-blind, placebo-controlled study. Sixty-nine...

journal_title：Scientific reports

authors： Ke MJ,Chen LC,Chou YC,Li TY,Chu HY,Tsai CK,Wu YT

更新日期：2016-12-02 00:00:00

abstract：:California has experienced a dry 21(st) century capped by severe drought from 2012 through 2015 prompting questions about hydroclimatic sensitivity to anthropogenic climate change and implications for the future. We address these questions using a Holocene lake sediment record of hydrologic change from the Sierra Neva...

journal_title：Scientific reports

authors： MacDonald GM,Moser KA,Bloom AM,Potito AP,Porinchu DF,Holmquist JR,Hughes J,Kremenetski KV

更新日期：2016-09-15 00:00:00

abstract：:COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with standard anti-tuberc...

journal_title：Scientific reports

authors： Naftalin CM,Verma R,Gurumurthy M,Hee KH,Lu Q,Yeo BCM,Tan KH,Lin W,Yu B,Seng KY,Lee LS,Paton NI

更新日期：2018-09-10 00:00:00

abstract：:Oral submucous fibrosis (OSF), regarded as a precancerous condition, is characterized by juxta-epithelial inflammatory reaction followed by fibro-elastic change in the lamina properia and epithelial atrophy. The pathologic mechanisms of OSF still need to be further clarified. In the study, we investigated the function...

journal_title：Scientific reports

authors： Yu CC,Yu CH,Chang YC

更新日期：2016-11-15 00:00:00

abstract：:We examine the spin-dependent manipulating of vector beams by tailoring the inhomogeneous polarization. The spin-dependent manipulating is attributed to the spin-dependent phase gradient in vector beams, which can be regarded as the intrinsic feature of inhomogeneous polarization. The desired polarization can be obtai...

journal_title：Scientific reports

authors： Zhou J,Zhang W,Liu Y,Ke Y,Liu Y,Luo H,Wen S

更新日期：2016-09-28 00:00:00

abstract：:Decreasing coral cover on the Great Barrier Reef (GBR) may provide opportunities for rapid growth and expansion of other taxa. The bioeroding sponges Cliona spp. are strong competitors for space and may take advantage of coral bleaching, damage, and mortality. Benthic surveys of the inshore GBR (2005-2014) revealed th...

journal_title：Scientific reports

authors： Ramsby BD,Hoogenboom MO,Whalan S,Webster NS,Thompson A

更新日期：2017-06-02 00:00:00

abstract：:In this work, a broadband and broad-angle polarization-independent random coding metasurface structure is proposed for radar cross section (RCS) reduction. An efficient genetic algorithm is utilized to obtain the optimal layout of the unit cells of the metasurface to get a uniform backscattering under normal incidence...

journal_title：Scientific reports

authors： Sun H,Gu C,Chen X,Li Z,Liu L,Xu B,Zhou Z

更新日期：2017-01-20 00:00:00

abstract：:Vapor-phase deposited polymer coatings are applied on thin indomethacin films to modify the drug release. Hydrogel-forming co-polymers of 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate were prepared directly on top of solution cast indomethacin thin films by initiated Chemical Vapor Deposition (iCVD). ...

journal_title：Scientific reports

authors： Christian P,Tumphart S,Ehmann HMA,Riegler H,Coclite AM,Werzer O

更新日期：2018-05-08 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, whole-transcriptome analysis was performed in 3 pairs of colorectal cancer (CRC) and matched normal mucosa (NM) by RNA sequencing (RNA-seq). Fol...

journal_title：Scientific reports

authors： Yamada A,Yu P,Lin W,Okugawa Y,Boland CR,Goel A

更新日期：2018-01-12 00:00:00

abstract：:Experimental evidence supports that signaling pathways can induce different dynamics of transcription factor (TF) activation, but how an input signal is encoded by such a dynamic, noisy TF and further decoded by downstream genes remains largely unclear. Here, using a system of stochastic transcription with signal regu...

journal_title：Scientific reports

authors： Liu P,Wang H,Huang L,Zhou T

更新日期：2017-02-08 00:00:00

abstract：:Mortuary practices in human evolution record cognitive, social changes and technological innovations. The Neolithic Revolution in the Levant was a watershed in this domain that has long fascinated the archaeological community. Plaster modelled skulls are well known at Jericho and several other Neolithic sites, and in ...

journal_title：Scientific reports

authors： Solazzo C,Courel B,Connan J,van Dongen BE,Barden H,Penkman K,Taylor S,Demarchi B,Adam P,Schaeffer P,Nissenbaum A,Bar-Yosef O,Buckley M

更新日期：2016-08-09 00:00:00

abstract：:Activities involving observation of wild organisms (e.g. wildlife watching, tidepooling) can provide recreational and learning opportunities, with biologically diverse animal assemblages expected to be more stimulating to humans. In turn, more diverse communities may enhance human interest and facilitate provisioning ...

journal_title：Scientific reports

authors： Fairchild TP,Fowler MS,Pahl S,Griffin JN

更新日期：2018-10-15 00:00:00

abstract：:Primary IgA nephropathy (IgAN) diagnosis is based on IgA-dominant glomerular deposits and histological scoring is done on formalin-fixed paraffin embedded tissue (FFPE) sections using the Oxford classification. Our aim was to use this underexploited resource to extract RNA and identify genes that characterize active (...

journal_title：Scientific reports

authors： Cox SN,Chiurlia S,Divella C,Rossini M,Serino G,Bonomini M,Sirolli V,Aiello FB,Zaza G,Squarzoni I,Gangemi C,Stangou M,Papagianni A,Haas M,Schena FP

更新日期：2020-09-16 00:00:00

abstract：:With the aim to dissect the effect of adult height on head and neck cancer (HNC), we use the Mendelian randomization (MR) approach to test the association between genetic instruments for height and the risk of HNC. 599 single nucleotide polymorphisms (SNPs) were identified as genetic instruments for height, accounting...

journal_title：Scientific reports

authors： Pastorino R,Puggina A,Carreras-Torres R,Lagiou P,Holcátová I,Richiardi L,Kjaerheim K,Agudo A,Castellsagué X,Macfarlane TV,Barzan L,Canova C,Thakker NS,Conway DI,Znaor A,Healy CM,Ahrens W,Zaridze D,Szeszenia-Dabrowska

更新日期：2018-03-14 00:00:00

abstract：:Actinobacillus pleuropneumoniae (App) is the causative agent of porcine pleuropneumonia. Although App produces several virulence factors, Apx toxins, the primary App virulence factors, have been the focus of numerous studies. However, the host response against the Apx toxins has not been elucidated at the transcriptom...

journal_title：Scientific reports

authors： Kim S,Oh MW,Bin Park W,Yoo HS

更新日期：2019-03-27 00:00:00

abstract：:Arbuscular mycorrhizal fungi (AMF) can be beneficial for improving restoration of radioactive-cesium (137Cs)-contaminated soils through soil remediation. However, there has been no information on species diversity and the composition of AMF communities in 137Cs-contaminated soil after the Fukushima-Daiichi Nuclear Pow...

journal_title：Scientific reports

authors： Higo M,Kang DJ,Isobe K

更新日期：2019-06-03 00:00:00

abstract：:Exploiting new, low-cost and efficient electrocatalysts for hydrogen evolution reaction (HER) is important to resolve the energy crisis and environment pollution. In this work, graphene decorated with Ni nanoparticles (NPs) were synthesized via one-pot reduction using graphene oxide (GO, the obtained composite was den...

journal_title：Scientific reports

authors： Zhang W,Li Y,Zeng X,Peng S

更新日期：2015-06-12 00:00:00

abstract：:The potential energy profile of an ideal binary switch is a symmetric double well. Switching between the wells without energy dissipation requires time-modulating the height of the potential barrier separating the wells and tilting the profile towards the desired well at the precise juncture when the barrier disappear...

journal_title：Scientific reports

authors： Fashami MS,Atulasimha J,Bandyopadhyay S

更新日期：2013-11-13 00:00:00

abstract：:Externally manipulating memories by presenting conditioned stimuli (CS) during sleep is a new approach to investigating memory processing during sleep. However, whether presenting a CS during REM or NREM sleep enhances or extinguishes fear memory has not been clearly delineated. In this study, mice underwent trace fea...

journal_title：Scientific reports

authors： Purple RJ,Sakurai T,Sakaguchi M

更新日期：2017-04-12 00:00:00

abstract：:Low miR-96-5p expression is characteristic of many cancers but its role in breast cancer (BCa) remains poorly defined. Here, the role of miR-96-5p in BC development was assessed. We demonstrate that exogenously expressing miR-96-5p inhibits the proliferative, migratory and invasive capacity of BCa cells. Mechanistical...

journal_title：Scientific reports

authors： Gao XH,Zhang YL,Zhang ZY,Guo SS,Chen XB,Guo YZ

更新日期：2020-01-08 00:00:00

abstract：:It is believed that motor performance improves when individuals direct attention to movement outcome (external focus, EF) rather than to body movement itself (internal focus, IF). However, our previous study found that an optimal individual attentional strategy depended on motor imagery ability. We explored whether th...

journal_title：Scientific reports

authors： Sakurada T,Nakajima T,Morita M,Hirai M,Watanabe E

更新日期：2017-01-17 00:00:00

abstract：:Global climate change (GCC) can negatively affect freshwater ecosystems. However, the degree to which freshwater populations can acclimate to long-term warming and the underlying molecular mechanisms are not yet fully understood. We used the cooling water discharge (CWD) area of a power plant as a model for long-term ...

journal_title：Scientific reports

authors： Falfushynska HI,Phan T,Sokolova IM

更新日期：2016-12-20 00:00:00