Abstract：
:California has experienced a dry 21(st) century capped by severe drought from 2012 through 2015 prompting questions about hydroclimatic sensitivity to anthropogenic climate change and implications for the future. We address these questions using a Holocene lake sediment record of hydrologic change from the Sierra Nevada Mountains coupled with marine sediment records from the Pacific. These data provide evidence of a persistent relationship between past climate warming, Pacific sea surface temperature (SST) shifts and centennial to millennial episodes of California aridity. The link is most evident during the thermal-maximum of the mid-Holocene (~8 to 3 ka; ka = 1,000 calendar years before present) and during the Medieval Climate Anomaly (MCA) (~1 ka to 0.7 ka). In both cases, climate warming corresponded with cooling of the eastern tropical Pacific despite differences in the factors producing increased radiative forcing. The magnitude of prolonged eastern Pacific cooling was modest, similar to observed La Niña excursions of 1(o) to 2 °C. Given differences with current radiative forcing it remains uncertain if the Pacific will react in a similar manner in the 21st century, but should it follow apparent past behavior more intense and prolonged aridity in California would result.
journal_name
Sci Repjournal_title
Scientific reportsauthors
MacDonald GM,Moser KA,Bloom AM,Potito AP,Porinchu DF,Holmquist JR,Hughes J,Kremenetski KVdoi
10.1038/srep33325subject
Has Abstractpub_date
2016-09-15 00:00:00pages
33325issn
2045-2322pii
srep33325journal_volume
6pub_type
杂志文章abstract：:The American mink (Neovison vison) is a semiaquatic species of mustelid native to North America. It's an important animal for the fur industry. Many efforts have been made to locate genes influencing fur quality and color, but this search has been impeded by the lack of a reference genome. Here we present the first dr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15169-z
更新日期：2017-11-06 00:00:00
abstract：:Silver has long been employed as an electrically conductive component, and morphology-dependent properties have been actively investigated. Here we present a novel scalable synthesis method of flower-shaped silver nanoparticles (silver nanoflowers, Ag NFs). The preferential affinity of citrate molecules on (111) surfa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34894
更新日期：2016-10-07 00:00:00
abstract：:IL-37 is a novel pro-angiogenic cytokine that potently promotes endothelial cell activation and pathological angiogenesis in our previous study, but the mechanisms behind the pro-angiogenic effect of IL-37 are less well understood. Extending our observations, we found that TGF-β interacts with IL-37, and potently enha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06124-z
更新日期：2017-07-21 00:00:00
abstract：:Obesity causes low-grade inflammation that is involved in male infertility. Interleukin 1 beta (IL1β) plays an important role in this process. A high-fat diet (HFD) is the most common cause of obesity. However, the effect of a HFD on IL1β and its consequence in reproduction remain unclear. We established a HFD model i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00505-0
更新日期：2017-04-03 00:00:00
abstract：:Studies in mice suggest that early life represents a critical time window, where antibiotics may exert profound and lasting effects on the gut microbiota and metabolism. We aimed to test the hypothesis that prenatal antibiotic exposure is associated with increased risk of childhood overweight in a population-based coh...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48065-9
更新日期：2019-08-08 00:00:00
abstract：:Living organisms have to adjust to their surrounding in order to survive in stressful conditions. We study this mechanism in one of most primitive creatures - photosynthetic green sulfur bacteria. These bacteria absorb photons very efficiently using the chlorosome antenna complexes and perform photosynthesis in extrem...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05057
更新日期：2014-05-27 00:00:00
abstract：:The biliary tree is an essential component of transplantable human liver tissue. Despite recent advances in liver tissue engineering, attempts at re-creating the intrahepatic biliary tree have not progressed significantly. The finer branches of the biliary tree are structurally and functionally complex and heterogeneo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30433-6
更新日期：2018-08-15 00:00:00
abstract：:Biological hydrogen production is based on activity of specific enzymes called hydrogenases. Hydrogenases are oxygen sensitive metalloenzymes containing Ni and/or Fe atoms at the active site, catalyzing reversible reduction of protons. Generally, [Fe-Fe] hydrogenases prefer proton reduction to molecular hydrogen, a po...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36034
更新日期：2016-10-27 00:00:00
abstract：:Similar to sleeping after learning, a brief period of wakeful resting after encoding new information supports memory retention in contrast to task-related cognition. Recent evidence suggests that working memory capacity (WMC) is related to sleep-dependent declarative memory consolidation. We tested whether WMC moderat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74760-z
更新日期：2020-10-21 00:00:00
abstract：:This study presents atomic scale characterization of grain boundary defect structure in a functional oxide with implications for a wide range of electrochemical and electronic behavior. Indeed, grain boundary engineering can alter transport and kinetic properties by several orders of magnitude. Here we report experime...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02680
更新日期：2013-01-01 00:00:00
abstract：:Scientific Reports 7: Article number: 45816; published online: 06 April 2017; updated: 16 May 2017. The original version of this Article contained an error in Affiliation 2, which was incorrectly given as: 'Department of Biophysics, School of Life Sciences, Manipal University, Manipal, 567014, India'. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46803
更新日期：2017-05-16 00:00:00
abstract：:Little research on coronaviruses has been conducted on wild animals in Africa. Here, we screened a wide range of wild animals collected in six provinces and five caves of Gabon between 2009 and 2015. We collected a total of 1867 animal samples (cave-dwelling bats, rodents, non-human primates and other wild animals). W...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64159-1
更新日期：2020-04-30 00:00:00
abstract：:The increase in volume and variety of pharmaceuticals found in natural water bodies has become an increasingly serious environmental problem. The implementation of cold plasma technology, specifically gas-phase pulsed corona discharge (PCD), for sulfamethizole abatement was studied in the present work. It was observed...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27061-5
更新日期：2018-06-07 00:00:00
abstract：:Short chain fatty acids (SCFAs) produced by intestinal microbes mediate anti-inflammatory effects, but whether they impact on antimicrobial host defenses remains largely unknown. This is of particular concern in light of the attractiveness of developing SCFA-mediated therapies and considering that SCFAs work as inhibi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37944
更新日期：2016-11-29 00:00:00
abstract：:A novel marine strain representing efficient degradation ability toward brown algae was isolated, identified, and assigned to Bacillus weihaiensis Alg07. The alga-associated marine bacteria promote the nutrient cycle and perform important functions in the marine ecosystem. The de novo sequencing of the B. weihaiensis ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38248
更新日期：2016-11-30 00:00:00
abstract：:IFI16 and AIM2 are important DNA sensors in antiviral immunity. To characterize these two molecules in a woodchuck model, which is widely used to study hepatitis B virus (HBV) infection, we cloned and analyzed the complete coding sequences (CDSs) of woodchuck IFI16 and AIM2, and found that AIM2 was highly conserved in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28776
更新日期：2016-06-29 00:00:00
abstract：:Histone methyltransferase EZH2 is upregulated during osteoarthritis (OA), which is the most widespread rheumatic disease worldwide, and a leading cause of disability. This study aimed to assess the impact of EZH2 inhibition on cartilage degradation, inflammation and functional disability. In vitro, gain and loss of EZ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76724-9
更新日期：2020-11-11 00:00:00
abstract：:Prostate cancer (PCa) is the most common malignancy and second leading cause of cancer-related deaths in American men. Proliferating cells have higher need for nutrients and oxygen, triggering angiogenesis that plays a critical role in tumor growth, progression and metastasis. Consequently, immense focus has converged...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27831-1
更新日期：2018-06-22 00:00:00
abstract：:Prophages are known to encode important virulence factors in the human pathogen Vibrio cholerae. However, little is known about the occurrence and composition of prophage-encoded traits in environmental vibrios. A database of 5,674 prophage-like elements constructed from 1,874 Vibrio genome sequences, covering sixty-f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28326-9
更新日期：2018-07-02 00:00:00
abstract：:Using time-gated fluorescence lifetime imaging microscopy, significantly more signals from 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide (o-BMVC) foci, characterized by the longer fluorescent decay time of o-BMVC, were detected in six types of cancer cells than in three types of normal cells. Accumulating ev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34378-8
更新日期：2018-10-31 00:00:00
abstract：:Alterations of carbohydrate structures in cancer cells are the most promising targets for developing clinical diagnostic reagents. Pancreatic cancer is one of the most difficult cancers to diagnose because it lacks definitive symptoms. Two antibodies were raised against human pancreatic ribonuclease 1 that bind to the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06715
更新日期：2014-10-22 00:00:00
abstract：:Electrochemical biosensors have been studied intensively for several decades. Numerous sensing concepts and related interface architectures have been developed. However, all such architectures suffer a trade-off: simple architectures favour usability, whereas complex architectures favour better performance. To overcom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04169
更新日期：2014-02-25 00:00:00
abstract：:Although it is clear that lipids are responsible for insulin resistance, it is poorly understood what types of lipids are involved. In this study, we verified the characteristic lipid species in skeletal muscle of a chronic exercise training model and a high-fat induced-obesity model. Three different lipidomics analys...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03267
更新日期：2013-11-20 00:00:00
abstract：:Metabolic images from Positron Emission Tomography (PET) are used routinely for diagnosis, follow-up or treatment planning purposes of cancer patients. In this study we aimed at determining if radiomic features extracted from 18F-Fluoro Deoxy Glucose (FDG) PET images could mirror tumor transcriptomics. In this study w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62414-z
更新日期：2020-03-27 00:00:00
abstract：:The Late Pleistocene Campanian Ignimbrite (CI) super-eruption (Southern Italy) is the largest known volcanic event in the Mediterranean area. The CI tephra is widely dispersed through western Eurasia and occurs in close stratigraphic association with significant palaeoclimatic and Palaeolithic cultural events. Here we...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45940
更新日期：2017-04-06 00:00:00
abstract：:Determining the success of eradication of an invasive species requires a way to decide when its risk of reoccurrence has become acceptably low. In Japan, the area populated by the Argentine ant, Linepithema humile (Mayr), is expanding, and eradication via chemical treatment is ongoing at various locations. One such pr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03516-z
更新日期：2017-06-13 00:00:00
abstract：:Inhibitor of kappa B (IκB)-ζ transcription is rapidly induced by stimulation with TLR ligands and IL-1. Despite high IκBζ expression in inflammation sites, the association of IκBζ with host defence via systemic immune responses against bacterial infection remains unclear. Oral immunisation with a recombinant attenuate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44019-3
更新日期：2019-06-10 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-35358-8
更新日期：2018-11-16 00:00:00
abstract：:Understanding how a species utilises its habitat, and the processes that give rise to its movements and patterns of space use, is critical for its conservation. Southern Ground-hornbills Bucorvus leadbeateri are listed as Endangered in South Africa, as a result of habitat loss and persecution. The National Species Rec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73236-4
更新日期：2020-10-01 00:00:00
abstract：:Pain is a highly unpleasant sensory and emotional experience, and no objective diagnosis test exists to assess it. In clinical practice there are two main methods for the estimation of pain, a patient's self-report and clinical judgement. However, these methods are highly subjective and the need of biomarkers to measu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42098-w
更新日期：2019-04-04 00:00:00
