Abstract：
:The potential energy profile of an ideal binary switch is a symmetric double well. Switching between the wells without energy dissipation requires time-modulating the height of the potential barrier separating the wells and tilting the profile towards the desired well at the precise juncture when the barrier disappears. This, however, demands perfect timing synchronization and is therefore fault-intolerant even in the absence of noise. A fault-tolerant strategy that requires no time modulation of the barrier (and hence no timing synchronization) switches by tilting the profile by an amount at least equal to the barrier height and dissipates at least that amount of energy in abrupt switching. Here, we present a third strategy that requires a time modulated barrier but no timing synchronization. It is therefore fault-tolerant, error-free in the absence of thermal noise, and yet it dissipates arbitrarily small energy in a noise-free environment since an arbitrarily small tilt is required for slow switching. This case is exemplified with stress induced switching of a shape-anisotropic single-domain soft nanomagnet dipole-coupled to a hard magnet. When thermal noise is present, we show analytically that the minimum energy dissipated to switch in this scheme is ~2kTln(1/p) [p = switching error probability].
journal_name
Sci Repjournal_title
Scientific reportsauthors
Fashami MS,Atulasimha J,Bandyopadhyay Sdoi
10.1038/srep03204subject
Has Abstractpub_date
2013-11-13 00:00:00pages
3204issn
2045-2322pii
srep03204journal_volume
3pub_type
杂志文章abstract：:In neuroblastoma (NB), one of the most common paediatric solid tumours, activation of anaplastic lymphoma kinase (ALK) is often associated with poor outcomes. Although genetic studies have identified copy number alteration and nonsynonymous mutations of ALK, the regulatory mechanism of ALK signalling at protein levels...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32682
更新日期：2016-09-08 00:00:00
abstract：:Second-harmonic generation (SHG) is the most specific label-free indicator of collagen accumulation in widespread pathologies such as fibrosis, and SHG-based measurements hold important potential for biomedical analyses. However, efficient collagen SHG scoring in histological slides is hampered by the limited depth-of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29863
更新日期：2016-07-20 00:00:00
abstract：:Human epididymis protein 4 (HE4) has been used as a biomarker of endometrial cancer (EC) in clinical practice. However, there remains a lack of systemic research on the critical values of HE4 for diagnosing different clinical stages and pathological types of EC. This study investigated the accuracy of human epididymis...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79960-1
更新日期：2021-01-12 00:00:00
abstract：:Insecticides and other agrochemicals have become indispensable components of the agricultural system to ensure a notable increase in crop yield and food production. As a natural consequence, chemical residues result in significantly increased contamination of both terrestrial and aquatic ecosystems. The present study ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76638-6
更新日期：2020-11-11 00:00:00
abstract：:Superconductivity within layered crystal structures has attracted sustained interest among condensed matter community, primarily due to their exotic superconducting properties. EuBiS2F is a newly discovered member in the BiS2-based superconducting family, which shows superconductivity at 0.3 K without extrinsic doping...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37394
更新日期：2016-11-22 00:00:00
abstract：:Familial breast cancer is estimated to account for 15-20% of all cases of breast cancer. Surveillance for familial breast cancer is well-established world-wide. However, this service does not exist in Jordan, due to the scarcity of information with regard to the genetic profiling of these patients, and therefore lack ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74250-2
更新日期：2020-10-16 00:00:00
abstract：:Genetically encoded calcium indicators and optogenetic actuators can report and manipulate the activity of specific neuronal populations. However, applying imaging and optogenetics simultaneously has been difficult to establish in the mammalian brain, even though combining the techniques would provide a powerful appro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40041
更新日期：2017-01-05 00:00:00
abstract：:In plants and parenchymatous brown algae the body arises through the activity of an apical meristem (a niche of cells or a single cell). The meristem produces lateral organs in specific patterns, referred to as phyllotaxis. In plants, two different control mechanisms have been proposed: one is position-dependent and r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13767-5
更新日期：2017-10-24 00:00:00
abstract：:Environmentally persistent free radicals (EPFRs) have attracted increasing research interest in recent years. Herein, the generation of EPFRs during the hydrothermal carbonization of sewage sludge (SS) was studied. First, the surface morphology, functional groups, constituent elements and free radicals were characteri...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53781-3
更新日期：2019-11-19 00:00:00
abstract：:Reperfusion alters post-myocardial infarction (MI) healing; however, very few systematic studies report the early molecular changes following ischemia/reperfusion (I/R). Alterations in the remote myocardium have also been neglected, disregarding its contribution to post-MI heart failure (HF) development. This study ch...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11985-5
更新日期：2017-09-27 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-63705-1
更新日期：2020-04-15 00:00:00
abstract：:Mammalian spermatogenesis is a classic adult stems cell-dependent process, supported by the self-renewal and differentiation of spermatogonial stem cells (SSCs). However, the identification of SSCs and elucidation of their behaviors in undisturbed testis has long been a big challenge. Here, we generated a knock-in mou...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17594
更新日期：2015-12-01 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60584-4
更新日期：2020-02-27 00:00:00
abstract：:To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-82010-z
更新日期：2021-01-27 00:00:00
abstract：:Analyzing heart rate variability (HRV) in preterm infants can help track maturational changes and subclinical signatures of disease. We conducted an observational study to characterize the effect of demographic and cardiorespiratory factors on three features of HRV using a linear mixed-effects model. HRV-features were...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44209-z
更新日期：2019-05-22 00:00:00
abstract：:Sharp declines in numerous shark populations around the world have generated considerable interest in better understanding and characterising their biology, ecology and critical habitats. The scalloped hammerhead shark (SHS, Sphyrna lewini) is subject to a multitude of natural and anthropogenic threats that are often ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17152-0
更新日期：2017-12-08 00:00:00
abstract：:The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the self-produced extracellular biofilm matrix confer high resistance to antibiotics, triggering infec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75929-2
更新日期：2020-11-03 00:00:00
abstract：:Copper (Cu), an essential nutrient, promotes wound healing, however, target of Cu action and underlying mechanisms remain elusive. Cu chaperone Antioxidant-1 (Atox1) in the cytosol supplies Cu to the secretory enzymes such as lysyl oxidase (LOX), while Atox1 in the nucleus functions as a Cu-dependent transcription fac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33783
更新日期：2016-09-26 00:00:00
abstract：:Bt cotton was genetically modified to produce insecticidal proteins targeting Lepidopteran pests and is therefore only minimally affected by caterpillar damage. This could lead to reduced levels of inherent, systemically inducible defensive compounds in Bt cotton which might benefit other important cotton herbivores s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38917-9
更新日期：2019-02-25 00:00:00
abstract：:Glacial refugia are centers of high biodiversity. Therefore, knowledge on their locations and reactions of associated populations and landscapes to climatic changes is crucial for conservation management. We here investigated the biogeography of a butterfly species linked to open forest habitats. Using mitochondrial a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79376-x
更新日期：2021-01-08 00:00:00
abstract：:Vertical mixing modulates nutrient dynamics in lakes. However, surface warming reduces the range of vertical mixing and the probability of full circulation events. Important consequences of reduced vertical mixing include the sequestration of phosphorus (P) within a stagnant zone and the promotion of oligotrophication...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69721-5
更新日期：2020-07-31 00:00:00
abstract：:Nutritional supplements may be important on cognition but the evidence is heterogeneous. This meta-analysis aimed (1) to determine whether nutritional supplements provided to pregnant women or young children could improve cognitive development of children in developing countries, and (2) to explore how supplementation...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-017-11023-4
更新日期：2017-09-06 00:00:00
abstract：:Giardia is a worldwide spread protozoan parasite colonizing in small intestines of vertebrates, causing Giardiasis. The controversy about whether it is an extremely primitive eukaryote or just a highly evolved parasite has become a fetter to its uses as a model for both evolutionary and parasitological studies for yea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10054-1
更新日期：2017-08-25 00:00:00
abstract：:We compared coincidence-anticipation performance in normal vision and stroboscopic vision as a function of time-on-task. Participants estimated the arrival time of a real object that moved with constant acceleration (-0.7, 0, +0.7 m/s2) in a pseudo-randomised order across 4 blocks of 30 trials in both vision condition...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18092-5
更新日期：2017-12-20 00:00:00
abstract：:Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among bacteria, yet, despite extensive studies in the last decade, their biological importance remains ambivalent. The ability of TA-encoded toxins to affect stress tolerance when overexpressed supports the hypothesis of TA systems being associat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65504-0
更新日期：2020-06-08 00:00:00
abstract：:The type II bacterial CRISPR/Cas9 system is rapidly becoming popular for genome-engineering due to its simplicity, flexibility, and high efficiency. Recently, targeted knock-in of a long DNA fragment via homology-independent DNA repair has been achieved in zebrafish using CRISPR/Cas9 system. This raised the possibilit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06545
更新日期：2014-10-08 00:00:00
abstract：:Invasive plant species often form dense mono-dominant stands in areas they have invaded, while having only sparse distribution in their native ranges, and the reasons behind this phenomenon are a key point of research in invasive species biology. Differences in species composition between native and invasive ranges ma...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16376-4
更新日期：2017-11-22 00:00:00
abstract：:Milk microbiota has a great influence on the safety and quality of dairy products. However, few studies have investigated the variations of bacterial composition in raw milk. In this study, raw milk samples were collected in 12 successive months, and their bacterial compositions were determined by 16 S rRNA gene seque...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20862-8
更新日期：2018-02-05 00:00:00
abstract：:Epigenetics alternation of non-genetic variation and genome-wide association study proven allelic variants may associate with insulin secretion in type 2 diabetes (T2D) development. We analyzed promoter DNA methylation array to evaluate the associated with increased susceptibility to T2D (30 cases, 10 controls) and fo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71336-9
更新日期：2020-09-30 00:00:00
abstract：:The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary. However, the events and conditions that lead to cancer cell implantati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30261-8
更新日期：2018-08-17 00:00:00
