Juvenile hormone regulates the steroidogenic competence of Manduca sexta prothoracic glands.

abstract：:The effects of cholera toxin on the responses of cultured Sertoli cells were compared with those elicited by follicle-stimulating hormone (FSH), and N6O2'-dibutyryl-3',5'-cyclic AMP (bu2cAMP). Addition of FSH or cholera toxin increased cAMP levels. Subsequently there was greater rates of conversion of testosterone to ...

journal_title：Molecular and cellular endocrinology

authors： Fritz IB,Griswold MD,Louis BG,Dorrington JH

更新日期：1976-08-01 00:00:00

abstract：:The regulation of the insulin receptor by cAMP has been examined in glial C6 cells. Incubation for 48 h with dibutyryl cyclic AMP produced a dose-dependent inhibition of 125I-insulin binding to the cells. Other agents that elevate intracellular cAMP levels such as forskolin and cholera toxin mimicked the effect of thi...

journal_title：Molecular and cellular endocrinology

authors： Montiel F,Aranda A,Pascual A

更新日期：1989-02-01 00:00:00

abstract：:We examined the effects of growth hormone (GH), prolactin (PRL) and insulin-like growth factor-I (IGF-I) on DNA synthesis, and insulin-like growth factor binding protein 3 (IGFBP-3) gene expression, in a rat beta-cell line INS-1. GH and PRL were equally effective in increasing DNA synthesis and IGFBP-3 gene expression...

journal_title：Molecular and cellular endocrinology

authors： De W,Bréant B,Czernichow P,Asfari M

更新日期：1995-10-30 00:00:00

abstract：:In man, two isoforms of growth hormone receptor (GHR) have been reported. The first, hGHR corresponds to the original form described by Leung et al. (J. Biol. Chem. 264 (1987) 9905-9910). The second, hGHRd3, missing 22 N-terminal amino acids is encoded by an mRNA derived from alternative splicing and deletion of the t...

journal_title：Molecular and cellular endocrinology

authors： Esposito N,Paterlini P,Kelly PA,Postel-Vinay MC,Finidori J

更新日期：1994-07-01 00:00:00

abstract：:The present study was conducted to investigate whether GnRH-receptor (GnRH-R) gene is expressed in endometriosis ovarian implants and whether a GnRH-analogue (GnRH-a) may exert an effect on endometriosis cell proliferation in vitro. The presence of GnRH-R transcripts in ovarian endometriosis cells was assessed by reve...

journal_title：Molecular and cellular endocrinology

authors： Borroni R,Di Blasio AM,Gaffuri B,Santorsola R,Busacca M,Viganò P,Vignali M

更新日期：2000-01-25 00:00:00

abstract：:The trafficking of fatty acids into and out of adipocytes is regulated by a complex series of proteins and enzymes and is under control by a variety of hormonal and metabolic factors. The biochemical basis of fatty acid influx, despite its widespread appreciation, remains enigmatic with regard to the biophysical and b...

journal_title：Molecular and cellular endocrinology

authors： Thompson BR,Lobo S,Bernlohr DA

更新日期：2010-04-29 00:00:00

abstract：:Protein biosynthesis in neurointermediate lobes of mouse pituitaries was investigated using pulse and pulse-chase techniques with [3H]lysine. Electrophoretic analysis of lobe homogenates on acid-urea gels resolved 11 labeled products. One was a large protein which was rapidly synthesized during pulse-incubations and d...

journal_title：Molecular and cellular endocrinology

authors： Jenks BG,Meulepas WJ,Soons PJ,van Overbeeke AP

更新日期：1979-02-01 00:00:00

abstract：:Effects of human retinoid X receptor alpha (hRXR alpha) and its ligand, 9-cis-retinoic acid, on T3-mediated auto-regulation of hTR beta 1 gene expression were examined using a chloramphenicol acetyltransferase (CAT) reporter system, and a deletional analysis of the promoter. hRXR alpha enhanced T3-dependent CAT induct...

journal_title：Molecular and cellular endocrinology

authors： Sakurai A,Suzuki S,Katai M,Miyamoto T,Kobayashi H,Nakajima K,Ichikawa K,DeGroot LJ,Hashizume K

更新日期：1995-04-28 00:00:00

abstract：:Inhibitor-1 following phosphorylation by protein kinase A inhibits phosphoprotein phosphatase-1. We have found that in the rat heart inhibitor-1 is present only in the cytosolic fraction and that its phosphorylation in ventricular slices was increased by isoproterenol but not by isoproterenol and propranolol together....

journal_title：Molecular and cellular endocrinology

authors： Iyer RB,Koritz SB,Kirchberger MA

更新日期：1988-01-01 00:00:00

abstract：:Thyroid oncocytic neoplasms are tumors composed of cells characterized by an aberrant increase of mitochondrial mass. They represent a subset of thyroid tumors whose classification and clinical features has been a matter of controversy for clinicians and pathologists alike. The prevalence of oncocytic tumors in the th...

journal_title：Molecular and cellular endocrinology

authors： Gasparre G,Bonora E,Tallini G,Romeo G

更新日期：2010-05-28 00:00:00

abstract：:Retinoic acid receptors (RARs) activate transcription by recruiting coactivator complexes such as histone acetyltransferases (HAT) and the mediator complex, to increase chromatin accessibility by general transcription factors and to promote transcription initiation. Indirect evidences have suggested a role for the ATP...

journal_title：Molecular and cellular endocrinology

authors： Flajollet S,Lefebvre B,Cudejko C,Staels B,Lefebvre P

更新日期：2007-05-30 00:00:00

abstract：:Dopamine and somatostatin are both involved in the negative control of normal pituitary cells. Dopamine subtype 2 receptor (D2DR) and somatostatin receptor (sst) agonists, mainly directed to sst2, are used in the treatment of pituitary adenomas. Nevertheless, a majority of corticotroph and gonadotroph adenomas and a t...

journal_title：Molecular and cellular endocrinology

authors： Saveanu A,Jaquet P,Brue T,Barlier A

更新日期：2008-05-14 00:00:00

abstract：:We have previously shown that the tyrosine kinase receptor Flk-1 and its ligand, vascular endothelial growth factor (VEGF), may play a role in the development of fetal rat islet-like structures in vitro, possibly by stimulating the maturation of endocrine precursor cells in the pancreatic ductal epithelium. In order t...

journal_title：Molecular and cellular endocrinology

authors： Oberg-Welsh C,Sandler S,Andersson A,Welsh M

更新日期：1997-02-07 00:00:00

abstract：:Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular ...

journal_title：Molecular and cellular endocrinology

authors： Chopin L,Walpole C,Seim I,Cunningham P,Murray R,Whiteside E,Josh P,Herington A

更新日期：2011-06-20 00:00:00

abstract：:Border cell migration is a process that occurs during Drosophila ovarian development in which cells derived from a simple epithelium migrate and invade neighboring tissue. This process resembles the behavior of cancerous cells that derive from the simple epithelium of the human ovary. One important regulator of border...

journal_title：Molecular and cellular endocrinology

authors： Yoshida H,Liu J,Samuel S,Cheng W,Rosen D,Naora H

更新日期：2005-12-21 00:00:00

abstract：:The functions of anterior pituitary cells are controlled by two major groups of hypothalamic and intrapituitary ligands: one exclusively acts on G protein-coupled receptors and the other activates both G protein-coupled receptors and ligand-gated receptor channels. The second group of ligands operates as neurotransmit...

journal_title：Molecular and cellular endocrinology

authors： Zemková H,Stojilkovic SS

更新日期：2018-03-05 00:00:00

abstract：:Osteoblastic metastases are common in patients with advanced prostate cancer. The pathophysiology of the new bone formation at metastatic sites is not currently known, but it is hypothesized that growth factors secreted by the prostate may be involved. Unfortunately, most rodent models of prostate cancer with metastas...

journal_title：Molecular and cellular endocrinology

authors： LeRoy BE,Bahnson RR,Rosol TJ

更新日期：2002-11-29 00:00:00

abstract：:The cDNA encoding the bovine activin type II receptor has been cloned by reverse transcription-polymerase chain reaction (RT-PCR) amplification of a bovine testicular RNA preparation. Sequence comparisons of the bovine activin type II receptor with its human, mouse and rat homologues show strong evolutionary conservat...

journal_title：Molecular and cellular endocrinology

authors： Ethier JF,Houde A,Lussier JG,Silversides DW

更新日期：1994-12-01 00:00:00

abstract：:The inappropriate expressions of insulin-like growth factors (IGF-I and II) and IGF-I receptor (IGF-IR) are implicated in the malignant growth of many cancers. To determine changes, if any, in the levels of expression of IGFs and IGF receptor genes in neoplastic endometrium, relative to normal endometrium, the mRNA le...

journal_title：Molecular and cellular endocrinology

authors： Roy RN,Gerulath AH,Cecutti A,Bhavnani BR

更新日期：1999-07-20 00:00:00

abstract：:Oestrogens are known to exert specific stimulatory effects on basal and dopamine (DA)-inhibited prolactin (PRL) release as well as on PRL cell content in rat adenohypophysial cells in primary culture. Recently, we have demonstrated that classical oestrogens increase growth hormone (GH) release and cellular GH content ...

journal_title：Molecular and cellular endocrinology

authors： Simard J,Vincent A,Duchesne R,Labrie F

更新日期：1988-02-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is essential for primate reproduction and acts via the FSH-receptor (FSHR). Although the FSHR expression is highly cell-specific, knowledge of the FSHR promoter and its transcriptional regulation is very limited. We applied a comparative genomic approach of important primate lineages...

journal_title：Molecular and cellular endocrinology

authors： Brune M,Adams C,Gromoll J

更新日期：2010-04-12 00:00:00

abstract：:The interaction between thyroid microsomal autoantibodies and thyroid microsomal antigen/thyroid peroxidase (TPO) has been studied using both intact antigen preparations and their water-soluble trypsin fragments. In an analysis of sera from 30 patients with Graves' or Hashimoto's diseases, microsomal antibodies showed...

journal_title：Molecular and cellular endocrinology

authors： Nakajima Y,Howells RD,Pegg C,Jones ED,Smith BR

更新日期：1987-09-01 00:00:00

abstract：:The initiation of transcription is accomplished via interactions of many different proteins with common and gene-specific regulatory motifs. Clearly, sequence-specific transcription factors play a crucial role in the specificity of transcription initiation. A group of sequence-specific DNA-binding proteins, related to...

journal_title：Molecular and cellular endocrinology

authors： Bouwman P,Philipsen S

更新日期：2002-09-30 00:00:00

abstract：:The aim of the present study was to identify the muscarinic acetylcholine receptor (mAChR) mRNA subtypes in the rat seminal vesicle. Furthermore, the mAChR subtypes involved in the contraction of the seminal vesicle were also explored. Reverse transcriptase-polymerase chain reaction (PCR) was performed and five PCR pr...

journal_title：Molecular and cellular endocrinology

authors： Hamamura M,Maróstica E,de Avellar MC,Porto CS

更新日期：2006-03-09 00:00:00

abstract：:The effects of thyroid hormone on insulin-like growth factor I (IGF-I) production by Sertoli cells isolated from immature rats have been investigated. In Sertoli cells from hypothyroid rats the production of IGF-I was significantly lower than in controls and was greatly stimulated by the administration of triiodothyro...

journal_title：Molecular and cellular endocrinology

authors： Palmero S,Prati M,Barreca A,Minuto F,Giordano G,Fugassa E

更新日期：1990-01-02 00:00:00

abstract：:Anti-Müllerian hormone (AMH) is expressed after birth in the ovary in the granulosa cells of healthy, small growing follicles. We have shown that AMH affects two important regulatory steps during folliculogenesis. At initial recruitment, AMH inhibits recruitment of primordial follicles into the growing pool, while at ...

journal_title：Molecular and cellular endocrinology

authors： Gruijters MJ,Visser JA,Durlinger AL,Themmen AP

更新日期：2003-12-15 00:00:00

abstract：:The ability of angiotensin-II (A-II) to increase cAMP production in adrenocortical cells is not widely accepted due to numerous conflicting reports. The recent observation that rat adrenal cells exhibit multiple subtypes of A-II receptors raises the possibility that a specific subtype could be responsible for controll...

journal_title：Molecular and cellular endocrinology

authors： Rainey WE,Byrd EW,Sinnokrot RA,Carr BR

更新日期：1991-10-01 00:00:00

abstract：:Presently, a growing interest is focused on the origins of the "Metabolic Syndrome", a cluster of several metabolic disorders linking obesity, dyslipidemia, hypertension and type 2 diabetes mellitus. Clearly, genetic predisposition and deleterious lifestyle, including low physical activity and hypercaloric alimentatio...

journal_title：Molecular and cellular endocrinology

authors： Somm E,Schwitzgebel VM,Vauthay DM,Aubert ML,Hüppi PS

更新日期：2009-05-25 00:00:00

abstract：:Meiosis-activating sterol (MAS) has been shown to induce mouse oocytes cultured in the presence of hypoxanthine (HX) to resume meiosis. The present research was conducted to determine whether amphotericin B or ketoconazole (a promoter and an inhibitor of production of MAS), affected oocyte maturation. Mouse cumulus ce...

journal_title：Molecular and cellular endocrinology

authors： Lu Z,Xia G,Byskov AG,Andersen CY

更新日期：2000-06-01 00:00:00

abstract：:Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are essential factors in mammary-gland (MG) development and are altered during fasting. However, no studies have investigated the alterations in the expression of GH/IGF-I and its regulatory systems (somatostatin/cortistatin and ghrelin) in MG during fasting...

journal_title：Molecular and cellular endocrinology

authors： Villa-Osaba A,Gahete MD,Cordoba-Chacon J,de Lecea L,Castaño JP,Luque RM

更新日期：2016-10-15 00:00:00