Active and passive sexual roles that arise in Drosophila male-male courtship are modulated by dopamine levels in PPL2ab neurons.

abstract：:Warburg effect or aerobic glycolysis provides selective growth advantage to aggressive cancers. However, targeting oncogenic regulators of Warburg effect has always been challenging owing to the wide spectrum of roles of these molecules in multitude of cells. In this study, we present ADP-dependent glucokinase (ADPGK)...

journal_title：Scientific reports

authors： Tandon A,Birkenhagen J,Nagalla D,Kölker S,Sauer SW

更新日期：2020-08-12 00:00:00

abstract：:Huntington disease (HD) is a late-onset genetic neurodegenerative disorder caused by expansion of cytosine-adenine-guanine (CAG) trinucleotide in the exon 1 of the gene encoding the polyglutamine (polyQ). It has been shown that protein degradation and lipid metabolism is altered in HD. In many neurodegenerative disord...

journal_title：Scientific reports

authors： Sameni S,Malacrida L,Tan Z,Digman MA

更新日期：2018-01-15 00:00:00

abstract：:We aimed to examine the prospective association between first trimester HbA1c and gestational diabetes (GDM) and explore the utility of HbA1c for prediction of GDM. We used data from a case-control study within the prospective NICHD Fetal Growth Studies-Singleton Cohort (2009-2013), which enrolled 2,802 women at 12 U....

journal_title：Scientific reports

authors： Hinkle SN,Tsai MY,Rawal S,Albert PS,Zhang C

更新日期：2018-08-16 00:00:00

abstract：:Recent studies of Asian glaciers have shown that glaciers in eastern Karakoram and West Kunlun have been slightly gaining mass while those in nearby Jammu Kashmir and Himalayas are losing mass, at rates of more than 0.5 m w.e.yr-1 and about 0.3 m w.e.yr-1, respectively. Two possible explanations have been proposed for...

journal_title：Scientific reports

authors： Sakai A,Fujita K

更新日期：2017-10-20 00:00:00

abstract：:Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or AdipoR2, into tibialis...

journal_title：Scientific reports

authors： Keshvari S,Henstridge DC,Ng C,Febbraio MA,Whitehead JP

更新日期：2017-02-01 00:00:00

abstract：:By means of extensive ab initio calculations, a new two-dimensional (2D) atomic material tin selenide monolayer (coined as tinselenidene) is predicted to be a semiconductor with an indirect gap (~1.45 eV) and a high hole mobility (of order 10000 cm(2)V(-1)S(-1)), and will bear an indirect-direct gap transition under a...

journal_title：Scientific reports

authors： Zhang LC,Qin G,Fang WZ,Cui HJ,Zheng QR,Yan QB,Su G

更新日期：2016-02-01 00:00:00

abstract：:The molecular dissociation constant, Kd, is a well-established parameter to quantitate the affinity of protein-protein or other molecular interactions. Recently, we reported the theoretical basis and experimental procedure for Kd determination using a quantitative FRET method. Here we report a new development of Kd de...

journal_title：Scientific reports

authors： Jiang L,Xiong Z,Song Y,Lu Y,Chen Y,Schultz JS,Li J,Liao J

更新日期：2019-02-14 00:00:00

abstract：:In this study, novel ZnS@In2S3 core@shell hollow nanospheres were fabricated by a facile refluxing method for the first time, and the formation mechanism of hollow structure with interior architecture was discussed based on ion-exchange Ostwald ripening. As the photocatalytic material for degradation of gaseous o-Dich...

journal_title：Scientific reports

authors： Liu B,Hu X,Li X,Li Y,Chen C,Lam KH

更新日期：2017-11-27 00:00:00

abstract：:Single nucleotide polymorphisms (SNPs) in commercial arrays have often been discovered in a small number of samples from selected populations. This ascertainment skews patterns of nucleotide diversity and affects population genetic inferences. We propose a demographic inference pipeline that explicitly models the SNP ...

journal_title：Scientific reports

authors： Quinto-Cortés CD,Woerner AE,Watkins JC,Hammer MF

更新日期：2018-07-05 00:00:00

abstract：:Proton pump inhibitors (PPIs) belong to the most common medication in geriatric medicine. They are known to reduce osteoclast activity and to delay fracture healing in young adult mice. Because differentiation and proliferation in fracture healing as well as pharmacologic actions of drugs markedly differ in the elderl...

journal_title：Scientific reports

authors： Menger MM,Bremer P,Scheuer C,Rollmann MF,Braun BJ,Herath SC,Orth M,Später T,Pohlemann T,Menger MD,Histing T

更新日期：2020-12-23 00:00:00

abstract：:The manuscript highlights the efficacy of silver ions to act as a unique probe for the detection of bacterial contamination in water samples. The bacterial cell membrane adherence property of the silver ions was employed to develop two different bacterial detection assays employing colorimetric and electrochemical tec...

journal_title：Scientific reports

authors： Kumar V,Chopra A,Bisht B,Bhalla V

更新日期：2020-07-20 00:00:00

abstract：:The endosymbiotic bacterium Wolbachia spreads rapidly through populations of Aedes aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue and Zika viruses. Mosquito control programs aimed at limiting transmission of these viruses are ongoing in multiple countries, yet there i...

journal_title：Scientific reports

authors： Dutra HLC,Rodrigues SL,Mansur SB,de Oliveira SP,Caragata EP,Moreira LA

更新日期：2017-11-16 00:00:00

abstract：:The novel nuclear protein nBMP2 is synthesized from the BMP2 gene by translational initiation at an alternative start codon. We generated a targeted mutant mouse, nBmp2NLStm, in which the nuclear localization signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 while still allowing the normal synthes...

journal_title：Scientific reports

authors： Cordner RD,Friend LN,Mayo JL,Badgley C,Wallmann A,Stallings CN,Young PL,Miles DR,Edwards JG,Bridgewater LC

更新日期：2017-04-18 00:00:00

abstract：:Some key behavioural traits of Autism Spectrum Disorders (ASD) have been hypothesized to be due to impairments in the early activation of subcortical orienting mechanisms, which in typical development bias newborns to orient to relevant social visual stimuli. A challenge to testing this hypothesis is that autism is us...

journal_title：Scientific reports

authors： Di Giorgio E,Frasnelli E,Rosa Salva O,Scattoni ML,Puopolo M,Tosoni D,NIDA-Network.,Simion F,Vallortigara G

更新日期：2016-05-20 00:00:00

abstract：:The ends of eukaryotic chromosomes are capped by telomeres which consist of tandem G-rich DNA repeats stabilized by the shelterin protein complex. Telomeres shorten progressively in most normal cells due to the end replication problem. In more than 85% of cancers however, the telomere length is maintained by telomeras...

journal_title：Scientific reports

authors： Hwang H,Opresko P,Myong S

更新日期：2014-09-29 00:00:00

abstract：:Altered neural mechanisms are well-acknowledged in irritable bowel syndrome (IBS), a disorder of brain-gut-communication highly comorbid with anxiety and depression. As a key hub in corticolimbic inhibition, medial prefrontal cortex (mPFC) may be involved in disturbed emotion regulation in IBS. However, aberrant mPFC ...

journal_title：Scientific reports

authors： Icenhour A,Tapper S,Bednarska O,Witt ST,Tisell A,Lundberg P,Elsenbruch S,Walter S

更新日期：2019-09-19 00:00:00

abstract：:Learning a skilled movement often requires changing multiple dimensions of movement in a coordinated manner. Serial training is one common approach to learning a new movement pattern, where each feature is learned in isolation from the others. Once one feature is learned, we move on to the next. However, when learning...

journal_title：Scientific reports

authors： Day KA,Bastian AJ

更新日期：2019-12-24 00:00:00

abstract：:Sacha inchi (Plukenetia volubilis L.) is a shrub native to Amazon rainforests that's of commercial interest as its seeds contain 35-60% edible oil (dry weight). This oil is one of the healthiest vegetable oils due to its high polyunsaturated fatty acid content and favourable ratio of omega-6 to omega-3 fatty acids. De...

journal_title：Scientific reports

authors： Liu G,Wu Z,Peng Y,Shang X,Xie Y,Arnold RJ

更新日期：2020-11-24 00:00:00

abstract：:Magnetic-charge ordering and corresponding magnetic/monopole phase transitions in spin ices are the emergent topics of condensed matter physics. In this work, we investigate a series of magnetic-charge (monopole) phase transitions in artificial square spin ice model using the conserved monopole density algorithm. It i...

journal_title：Scientific reports

authors： Xie YL,Du ZZ,Yan ZB,Liu JM

更新日期：2015-10-29 00:00:00

abstract：:Therizinosaurian theropods evolved many highly specialized osteological features in association with their bulky proportions, which were unusual in the context of the generally gracile Theropoda. Here we report a new therizinosaur, Lingyuanosaurus sihedangensis gen. et sp. nov., based on a specimen recovered from the ...

journal_title：Scientific reports

authors： Yao X,Liao CC,Sullivan C,Xu X

更新日期：2019-03-22 00:00:00

abstract：:Emergence and time evolution of micro-structured new-phase domains play a crucial role in determining the macroscopic physical and mechanical behaviors of iron under shock compression. Here, we investigate, through molecular dynamics simulations and theoretical modelings, shock-induced phase transition process of iron...

journal_title：Scientific reports

authors： Pang WW,Zhang P,Zhang GC,Xu AG,Zhao XG

更新日期：2014-01-10 00:00:00

abstract：:Voice disorder such as vocal fatigue is a common and complex multifaceted clinical problem that presents a significant impact on quality of life. In this study, the functional near-infrared diffuse optical technique (fNIRS-DOT) was proposed as a novel approach for human vocal cords oxidative metabolism detection and a...

journal_title：Scientific reports

authors： Lin TC,Chen JC,Liu CH,Lee CY,Tsou YA,Chuang CC

更新日期：2017-12-05 00:00:00

abstract：:Cytotoxic T lymphocyte (CTL) responses against the HIV Gag protein are associated with lowering viremia; however, immune control is undermined by viral escape mutations. The rapid viral mutation rate is a key factor, but recombination may also contribute. We hypothesized that CTL responses drive the outgrowth of uniqu...

journal_title：Scientific reports

authors： Chang CH,Kist NC,Stuart Chester TL,Sreenu VB,Herman M,Luo M,Lunn D,Bell J,Plummer FA,Ball TB,Katzourakis A,Iversen AK

更新日期：2015-06-17 00:00:00

abstract：:We propose a method for dual-channel near-field manipulations by designing isotropic but inhomogeneous metasurfaces. As example, we present a dual-channel near-field focusing metasurface device. When the device is driven by surface waves from different channels on the metasurface, the near fields will be focused at th...

journal_title：Scientific reports

authors： Wan X,Cai BG,Li YB,Cui TJ

更新日期：2015-11-03 00:00:00

abstract：:Cross-talk between exogenous salicylic acid (SA) and endogenous phytohormone pathways affects the antioxidant defense system and its response to salt stress. The study presented here investigated the effects of SA treatment before and during salt stress on the levels of endogenous plant growth regulators in three barl...

journal_title：Scientific reports

authors： Torun H,Novák O,Mikulík J,Pěnčík A,Strnad M,Ayaz FA

更新日期：2020-08-17 00:00:00

abstract：:Wolbachia, an endosymbiotic alpha-proteobacterium commonly found in insects, can inhibit the transmission of human pathogens by mosquitoes. Biocontrol programs are underway using Aedes aegypti mosquitoes trans-infected with a non-natural Wolbachia strain to reduce dengue virus transmission. Less is known about the imp...

journal_title：Scientific reports

authors： Straub TJ,Shaw WR,Marcenac P,Sawadogo SP,Dabiré RK,Diabaté A,Catteruccia F,Neafsey DE

更新日期：2020-08-14 00:00:00

abstract：:Local communities are assembled from larger-scale species pools via dispersal, environmental filtering, biotic interactions, and local stochastic demographic processes. The relative importance, scaling and interplay of these assembly processes can be elucidated by comparing local communities to variously circumscribed...

journal_title：Scientific reports

authors： Feng G,Mi X,Eiserhardt WL,Jin G,Sang W,Lu Z,Wang X,Li X,Li B,Sun I,Ma K,Svenning JC

更新日期：2015-03-23 00:00:00

abstract：:We discovered a technical solution of such outstanding importance that it can trigger new approaches in silicon wet etching processing and, in particular, photovoltaic cell manufacturing. The so called inverted pyramid arrays, outperforming conventional pyramid textures and black silicon because of their superior ligh...

journal_title：Scientific reports

authors： Wang Y,Yang L,Liu Y,Mei Z,Chen W,Li J,Liang H,Kuznetsov A,Xiaolong D

更新日期：2015-06-02 00:00:00

abstract：:The distribution of corals in Japan covers a wide range of latitudes, encompassing tropical to temperate zones. However, coral communities in temperate zones contain only a small subset of species. Among the parameters that determine the distribution of corals, temperature plays an important role. We tested the resili...

journal_title：Scientific reports

authors： Higuchi T,Agostini S,Casareto BE,Suzuki Y,Yuyama I

更新日期：2015-12-18 00:00:00

abstract：:Different classical theories are commonly applied in various branches of physics to describe the relativistic dynamics of electrons by coupled equations for the orbital motion and spin precession. Exemplarily, we benchmark the Frenkel model and the classical Foldy-Wouthuysen model with spin-dependent forces (Stern-Ger...

journal_title：Scientific reports

authors： Wen M,Bauke H,Keitel CH

更新日期：2016-08-22 00:00:00