Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells.

abstract：:Cystatin C (CysC) is implicated in neuroprotection and repair in the nervous system in response to diverse neurotoxic conditions. In addition to being secreted from cells in a soluble form, CysC is released by cells in association with extracellular vesicles (EVs), including exosomes. We demonstrate that EVs containin...

journal_title：Scientific reports

authors： Pérez-González R,Sahoo S,Gauthier SA,Kim Y,Li M,Kumar A,Pawlik M,Benussi L,Ghidoni R,Levy E

更新日期：2019-07-31 00:00:00

abstract：:Multiple infections of avian influenza viruses (AIVs) in poultry or wild birds contribute to the continued evolution of H5 subtype viruses in nature and provide potential recombination of AIVs of different origins. In this study, we carried out surveillance of AIVs in ducks, geese and the environment of a community in...

journal_title：Scientific reports

authors： Li X,Yang J,Liu B,Jia Y,Guo J,Gao X,Weng S,Yang M,Wang L,Wang LF,Cui J,Chen H,Zhu Q

更新日期：2016-05-06 00:00:00

abstract：:When we feel sad or depressed, our face invariably "drops". Conversely, when we try to cheer someone up, we might tell them "keep your smile up", so presupposing that modifying the configuration of their facial muscles will enhance their mood. A crucial assumption that underpins this hypothesis is that mental states a...

journal_title：Scientific reports

authors： Bulnes LC,Mariën P,Vandekerckhove M,Cleeremans A

更新日期：2019-08-13 00:00:00

abstract：:The Raman spectral features from spinal cord tissue sections of transgenic, ALS model mice and non-transgenic mice were compared using 457 nm excitation line, profiting from the favourable signal intensity obtained in the molecular fingerprint region at this wavelength. Transverse sections from four SOD1G93A mice at 7...

journal_title：Scientific reports

authors： Picardi G,Spalloni A,Generosi A,Paci B,Mercuri NB,Luce M,Longone P,Cricenti A

更新日期：2018-08-30 00:00:00

abstract：:PageRank is arguably the most popular ranking algorithm which is being applied in real systems ranging from information to biological and infrastructure networks. Despite its outstanding popularity and broad use in different areas of science, the relation between the algorithm's efficacy and properties of the network ...

journal_title：Scientific reports

authors： Mariani MS,Medo M,Zhang YC

更新日期：2015-11-10 00:00:00

abstract：:Articular cartilage (AC) lacks the ability to self-repair and cell-based approaches, primarily based on using chondrocytes and mesenchymal stem cells (MSCs), are emerging as effective technology to restore cartilage functionality, because cells synergic functionality may support the maintenance of chondrogenic phenoty...

journal_title：Scientific reports

authors： Scalzone A,Ferreira AM,Tonda-Turo C,Ciardelli G,Dalgarno K,Gentile P

更新日期：2019-10-10 00:00:00

abstract：:Dysfunctional epicardial adipose tissue (EAT) secretome can influence the heart's stretch response. However, the molecular mechanisms are still poorly understood. The aim of this study was to clarify how dysfunctional EAT promotes maladaptive heart remodeling in cardiovascular disease (CVD) through ST2 production asso...

journal_title：Scientific reports

authors： Vianello E,Dozio E,Bandera F,Schmitz G,Nebuloni M,Longhi E,Tacchini L,Guazzi M,Corsi Romanelli MM

更新日期：2019-07-17 00:00:00

abstract：:Salinity is a critical abiotic stress, which significantly impacts the agricultural yield worldwide. Identification of the molecular mechanisms underlying the salt tolerance in euhalophyte Suaeda salsa is conducive to the development of salt-resistant crops. In the present study, high-throughput RNA sequencing was per...

journal_title：Scientific reports

authors： Zhang X,Yao Y,Li X,Zhang L,Fan S

更新日期：2020-03-06 00:00:00

abstract：:In this paper, a new strategy is reported for preparing a label-free β-trophin electrochemiluminescent (ECL) immunosensor with good specificity, reproducibility and stability. An aquagel polymer from the hydrolysis of (3-aminopropyl) trimethoxysilane acted as the linker to catch the Au nanoparticles (AuNPs) on the ind...

journal_title：Scientific reports

authors： Zheng L,Fang C,Yan J,Li H,Tu Y

更新日期：2017-09-11 00:00:00

abstract：:Membrane protein oligomerization mediates a wide range of biological events including signal transduction, viral infection and membrane curvature induction. However, the relative contributions of protein-protein and protein-membrane interactions to protein oligomerization remain poorly understood. Here, we used the Ca...

journal_title：Scientific reports

authors： Tao M,Isas JM,Langen R

更新日期：2020-03-24 00:00:00

abstract：:COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with standard anti-tuberc...

journal_title：Scientific reports

authors： Naftalin CM,Verma R,Gurumurthy M,Hee KH,Lu Q,Yeo BCM,Tan KH,Lin W,Yu B,Seng KY,Lee LS,Paton NI

更新日期：2018-09-10 00:00:00

abstract：:We investigate the role of the spatial evolution of the acoustic field in stimulated Brillouin scattering processes in short high-gain structures. When the gain is strong enough that the gain length becomes comparable to the acoustic wave decay length of order 100 microns, standard approximations treating the acoustic...

journal_title：Scientific reports

authors： Wolff C,Steel MJ,Eggleton BJ,Poulton CG

更新日期：2015-09-04 00:00:00

abstract：:Cohesins are vital for chromosome organisation during meiosis and mitosis. In addition to the important function in sister chromatid cohesion, these complexes play key roles in meiotic recombination, DSB repair, homologous chromosome pairing and segregation. Egg-laying mammals (monotremes) feature an unusually complex...

journal_title：Scientific reports

authors： Casey AE,Daish TJ,Barbero JL,Grützner F

更新日期：2017-06-26 00:00:00

abstract：:Vitamin D is important in multiple health conditions. Vitamin D deficiency is prevalent globally even with exposure to adequate sunlight. Reduction in provitamin D3 (7-dehydrocholesterol, 7-DHC) is an important cause of vitamin D3 deficiency. Vitamin supplementation, food fortification, and use of probiotics are some ...

journal_title：Scientific reports

authors： Gokhale S,Bhaduri A

更新日期：2019-12-17 00:00:00

abstract：:Haber-Bosch nitrogen (N) has been increasingly used in industrial products, e.g., nylon, besides fertilizer. Massive numbers of species of industrial reactive N (Nr) have emerged and produced definite consequences but receive little notice. Based on a comprehensive inventory, we show that (1) the industrial N flux has...

journal_title：Scientific reports

authors： Gu B,Chang J,Min Y,Ge Y,Zhu Q,Galloway JN,Peng C

更新日期：2013-01-01 00:00:00

abstract：:The ionizing radiation in aqueous solutions of gold nanoparticles, stabilized by electrostatic non-covalent intermolecular forces and steric interactions, with antimicrobial compounds, are investigated with picosecond pulse radiolysis techniques. Upon pulse radiolysis of an aqueous solution containing very low concent...

journal_title：Scientific reports

authors： Ghandi K,Wang F,Landry C,Mostafavi M

更新日期：2018-05-08 00:00:00

abstract：:Archaeologically defined Upper Palaeolithic (UP, 45,000-10,000 years ago) "cultures" are often used as proxies to designate fossil populations. While recent genomic studies have partly clarified the complex relationship between European UP "cultures" and past population dynamics, they leave open numerous questions reg...

journal_title：Scientific reports

authors： Mounier A,Heuzé Y,Samsel M,Vasilyev S,Klaric L,Villotte S

更新日期：2020-12-14 00:00:00

abstract：:Echovirus 11 (E-11) is one of the most frequently isolated enteroviruses causing meningitis and other diseases such as hand, foot, and mouth disease (HFMD) and acute flaccid paralysis (AFP). Fifty-nine newly determined E-11 VP1 sequences from the China AFP and HFMD surveillance network and 500 E-11 VP1 sequences obtai...

journal_title：Scientific reports

authors： Li J,Yan D,Chen L,Zhang Y,Song Y,Zhu S,Ji T,Zhou W,Gan F,Wang X,Hong M,Guan L,Shi Y,Wu G,Xu W

更新日期：2019-07-22 00:00:00

abstract：:Hungarians who live in Central Europe today are one of the westernmost Uralic speakers. Despite of the proposed Volga-Ural/West Siberian roots of the Hungarian language, the present-day Hungarian gene pool is highly similar to that of the surrounding Indo-European speaking populations. However, a limited portion of sp...

journal_title：Scientific reports

authors： Post H,Németh E,Klima L,Flores R,Fehér T,Türk A,Székely G,Sahakyan H,Mondal M,Montinaro F,Karmin M,Saag L,Yunusbayev B,Khusnutdinova EK,Metspalu E,Villems R,Tambets K,Rootsi S

更新日期：2019-05-24 00:00:00

abstract：:How the human auditory system learns to map complex pinna-induced spectral-shape cues onto veridical estimates of sound-source elevation in the median plane is still unclear. Earlier studies demonstrated considerable sound-localisation plasticity after applying pinna moulds, and to altered vision. Several factors may ...

journal_title：Scientific reports

authors： Zonooz B,Arani E,Opstal AJV

更新日期：2018-12-18 00:00:00

abstract：:The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been implicated in regulation (tcdR and tcdC) and secretion (tcdE). To date, the PaLoc has always been found ...

journal_title：Scientific reports

authors： Monot M,Eckert C,Lemire A,Hamiot A,Dubois T,Tessier C,Dumoulard B,Hamel B,Petit A,Lalande V,Ma L,Bouchier C,Barbut F,Dupuy B

更新日期：2015-10-08 00:00:00

abstract：:The irritant receptor TRPA1 was suggested to mediate analgesic, antipyretic but also pro-inflammatory effects of the non-opioid analgesic acetaminophen, presumably due to channel activation by the reactive metabolites parabenzoquinone (pBQ) and N-acetyl-parabenzoquinonimine (NAPQI). Here we explored the effects of the...

journal_title：Scientific reports

authors： Eberhardt MJ,Schillers F,Eberhardt EM,Risser L,de la Roche J,Herzog C,Echtermeyer F,Leffler A

更新日期：2017-10-06 00:00:00

abstract：:The Morris Water Maze is a widely used task in studies of spatial learning with rodents. Classical performance measures of animals in the Morris Water Maze include the escape latency, and the cumulative distance to the platform. Other methods focus on classifying trajectory patterns to stereotypical classes representi...

journal_title：Scientific reports

authors： Gehring TV,Luksys G,Sandi C,Vasilaki E

更新日期：2015-10-01 00:00:00

abstract：:Although chronic kidney disease (CKD) is associated with functional decline, whether proteinuria alone is associated with functional statuses over the course of acute illnesses independent of CKD is unclear. During 2014, we prospectively enrolled non-dialysis patients aged ≥65 years, and all participants underwent spo...

journal_title：Scientific reports

authors： Chao CT,Tsai HB,Chiang CK,Huang JW,Hung KY

更新日期：2017-02-08 00:00:00

abstract：:Circulating tumor cells (CTC) have been studied extensively in various tumor types and are a well-established prognosticator in colorectal cancer (CRC). This is the first study to isolate CTC directly from the tumor outflow in secondary lung tumors. For this purpose in 24 patients with CRC who underwent pulmonary meta...

journal_title：Scientific reports

authors： Le UT,Bronsert P,Picardo F,Riethdorf S,Haager B,Rylski B,Czerny M,Beyersdorf F,Wiesemann S,Pantel K,Passlick B,Kaifi JT,Schmid S

更新日期：2018-06-08 00:00:00

abstract：:We introduce multi-gradients including Laplace pressure gradient, wettable gradient and wettable different gradient on a high adhesion surface via special wedge-pattern and improved anodic oxidation method. As a result of the cooperative effect mentioned above, controlled directional motion of a droplet on a high adhe...

journal_title：Scientific reports

authors： Deng S,Shang W,Feng S,Zhu S,Xing Y,Li D,Hou Y,Zheng Y

更新日期：2017-04-03 00:00:00

abstract：:An increasing number of industrial applications need superstrength steels. It is known that refined grains and nanoscale precipitates can increase strength. The hardest martensitic steel reported to date is C0.8 steel, whose nanohardness can reach 11.9 GPa through incremental interstitial solid solution strengthening....

journal_title：Scientific reports

authors： Yu H,Yan M,Lu C,Tieu AK,Li H,Zhu Q,Godbole A,Li J,Su L,Kong C

更新日期：2016-11-28 00:00:00

abstract：:Silver nanowires have attracted much attention for use in flexible transparent conductive films (TCFs) due to their low sheet resistance and flexibility. However, the haze was too high for replacing indium-tin-oxide in high-quality display devices. Herein, we report flexible TCFs, which were prepared using a scalable ...

journal_title：Scientific reports

authors： Menamparambath MM,Ajmal CM,Kim KH,Yang D,Roh J,Park HC,Kwak C,Choi JY,Baik S

更新日期：2015-11-17 00:00:00

abstract：:Transcription activator-like effector (TALE) nuclease (TALEN) is a site-specific nuclease, which can be freely designed and easily constructed. Numerous methods of constructing TALENs harboring different TALE scaffolds and repeat variants have recently been reported. However, the functionalities of structurally differ...

journal_title：Scientific reports

authors： Sakuma T,Ochiai H,Kaneko T,Mashimo T,Tokumasu D,Sakane Y,Suzuki K,Miyamoto T,Sakamoto N,Matsuura S,Yamamoto T

更新日期：2013-11-29 00:00:00

abstract：:Although intestinal trefoil factor (ITF) can alleviate the burn-induced intestinal mucosa injury, the underlying mechanisms remains elusive. In this study, we investigated if ITF alters glutamine transport on the brush border membrane vesicles (BBMVs) of the intestines in Sprague-Dawley rats inflicted with 30% TBSA an...

journal_title：Scientific reports

authors： Hu J,Shi Y,Wang C,Wan H,Wu D,Wang H,Peng X

更新日期：2018-02-16 00:00:00