Abstract:
:The Morris Water Maze is a widely used task in studies of spatial learning with rodents. Classical performance measures of animals in the Morris Water Maze include the escape latency, and the cumulative distance to the platform. Other methods focus on classifying trajectory patterns to stereotypical classes representing different animal strategies. However, these approaches typically consider trajectories as a whole, and as a consequence they assign one full trajectory to one class, whereas animals often switch between these strategies, and their corresponding classes, within a single trial. To this end, we take a different approach: we look for segments of diverse animal behaviour within one trial and employ a semi-automated classification method for identifying the various strategies exhibited by the animals within a trial. Our method allows us to reveal significant and systematic differences in the exploration strategies of two animal groups (stressed, non-stressed), that would be unobserved by earlier methods.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Gehring TV,Luksys G,Sandi C,Vasilaki Edoi
10.1038/srep14562subject
Has Abstractpub_date
2015-10-01 00:00:00pages
14562issn
2045-2322pii
srep14562journal_volume
5pub_type
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