Abstract:
:The ionizing radiation in aqueous solutions of gold nanoparticles, stabilized by electrostatic non-covalent intermolecular forces and steric interactions, with antimicrobial compounds, are investigated with picosecond pulse radiolysis techniques. Upon pulse radiolysis of an aqueous solution containing very low concentrations of gold nanoparticles with naked surfaces available in water (not obstructed by chemical bonds), a change to Cerenkov spectrum over a large range of wavelengths are observed and pre-solvated electrons are captured by gold nanoparticles exclusively (not by ionic liquid surfactants used to stabilize the nanoparticles). The solvated electrons are also found to decay rapidly compared with the decay kinetics in water. These very fast reactions with electrons in water could provide an enhanced oxidizing zone around gold nanoparticles and this could be the reason for radio sensitizing behavior of gold nanoparticles in radiation therapy.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ghandi K,Wang F,Landry C,Mostafavi Mdoi
10.1038/s41598-018-25711-2subject
Has Abstractpub_date
2018-05-08 00:00:00pages
7258issue
1issn
2045-2322pii
10.1038/s41598-018-25711-2journal_volume
8pub_type
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