Abstract：
:In utero and upon delivery, neonates are exposed to a wide array of microorganisms from various sources, including maternal bacteria. Prior studies have proposed that the mode of feeding shapes the gut microbiota and, subsequently the child's health. However, the effect of the mode of feeding and its influence on the development of the neonatal oral microbiota in early infancy has not yet been reported. The aim of this study was to compare the oral microbiota of healthy infants that were exclusively breast-fed or formula-fed using 16S-rRNA gene sequencing. We demonstrated that the oral bacterial communities were dominated by the phylum Firmicutes, in both groups. There was a higher prevalence of the phylum Bacteroidetes in the mouths of formula-fed infants than in breast-fed infants (p = 0.01), but in contrast Actinobacteria were more prevalent in breast-fed babies; Proteobacteria was more prevalent in saliva of breast-fed babies than in formula-fed neonates (p = 0.04). We also found evidence suggesting that the oral microbiota composition changed over time, particularly Streptococcus species, which had an increasing trend between 4-8 weeks in both groups. This study findings confirmed that the mode of feeding influences the development of oral microbiota, and this may have implications for long-term human health.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Al-Shehri SS,Sweeney EL,Cowley DM,Liley HG,Ranasinghe PD,Charles BG,Shaw PN,Vagenas D,Duley JA,Knox CLdoi
10.1038/srep38309subject
Has Abstractpub_date
2016-12-06 00:00:00pages
38309issn
2045-2322pii
srep38309journal_volume
6pub_type
杂志文章abstract：:Gold nanoparticles have particular properties distinct from those of bulk gold crystals, and such nanoparticles are used in various applications in optics, catalysis, and drug delivery. Many reports on microbial synthesis of gold nanoparticles have appeared. However, the molecular details (reduction and dispersion) of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34626
更新日期：2016-10-11 00:00:00
abstract：:In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST sub...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04208
更新日期：2014-02-27 00:00:00
abstract：:The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Fl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41906
更新日期：2017-02-06 00:00:00
abstract：:The study was aimed to evaluate the performance of a newly developed non-invasive and non-contact bilirubin measurement device (AJO-Neo) as an alternative to the conventional invasive biochemical method of total serum bilirubin (TSB) estimation in preterm and term neonates suffering from hyperbilirubinemia associated ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67981-9
更新日期：2020-07-07 00:00:00
abstract：:Glial cell-derived neurotrophic factor (GDNF) has shown beneficial effects in models of Parkinson's disease. The mild results observed in the double-blind clinical trial by intraputamenal infusion of recombinant GDNF proteins warrant a search for alternative delivery methods. In this study, we investigated the functio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02786
更新日期：2013-09-27 00:00:00
abstract：:Self-cleaving ribozymes fold into intricate structures, which orient active site groups into catalytically competent conformations. Most ribozyme families have distinct catalytic cores stabilized by tertiary interactions between domains peripheral to those cores. We show that large hepatitis delta virus (HDV)-like rib...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28179
更新日期：2016-06-15 00:00:00
abstract：:Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep07024
更新日期：2014-11-12 00:00:00
abstract：:Patients with chronic obstructive pulmonary disease (COPD) repeat acute exacerbations (AE). Global Initiative for Chronic Obstructive Lung Disease (GOLD) is only available for patients in stable phase. Currently, there is a lack of assessment and prediction methods for acute exacerbation of chronic obstructive pulmona...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60042-1
更新日期：2020-02-20 00:00:00
abstract：:Epsilon-Near-Zero materials exhibit a transition in the real part of the dielectric permittivity from positive to negative value as a function of wavelength. Here we study metal-dielectric layered metamaterials in the homogenised regime (each layer has strongly subwavelength thickness) with zero real part of the permi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27700
更新日期：2016-06-13 00:00:00
abstract：:Graphene oxide-silver (Ag-GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag-GO nanocomposite formation excluding the aid of surfactants and reductants and was successfully applied to negative Escherichia Coli (E coli) to investigate antiba...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80013-w
更新日期：2021-01-08 00:00:00
abstract：:APOBEC3G (A3G) belongs to the family of cytosine deaminases that play an important role in the innate immune response. Similar to other, two-domain members of the APOBEC family, A3G is prone to concentration-dependent oligomerization, which is an integral for its function in the cell. It is shown that oligomerization ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36372-6
更新日期：2018-12-18 00:00:00
abstract：:Culture expanded mesenchymal stromal cells (MSCs) are being extensively studied for therapeutic applications, including treatment of graft-versus-host disease, osteogenesis imperfecta and for enhancing engraftment of hematopoietic stem cells after transplantation. Thus far, clinical trials have shown that the therapeu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50955-x
更新日期：2019-10-07 00:00:00
abstract：:The rapid pace of conversion of natural areas to agricultural systems is highly concerning, and the consequences for conservation and pest management are not yet fully understood. We examined mitochondrial (COI and Cytb) and nuclear (ITS1) gene regions of 21 populations of the stink bug Euschistus heros, to investigat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20187-6
更新日期：2018-02-06 00:00:00
abstract：:HIV-1 Tat plays an important role in HIV-associated neurocognitive disorders (HAND) by disrupting neurotransmission including dopamine uptake by human dopamine transporter (hDAT). Previous studies have demonstrated that HIV-1 Tat directly binds to hDAT and some amino-acid mutations that attenuate the hDAT-Tat binding ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27314
更新日期：2016-06-02 00:00:00
abstract：:In the study, we analyzed role of p53 in predicting outcome in visceral metastasis breast cancer (VMBC) patients. 97 consecutive VMBC patients were studied. P53 positivity rate was 29.9%. In the p53-negative group, median disease free survival (DFS), and time from primary breast cancer diagnosis to death (OS1), time f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02246
更新日期：2013-01-01 00:00:00
abstract：:Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid tumors ablation, under clinical investigation for cancer therapy. IRE affects only the cell membrane, killing cells while preserving the extracellular matrix structure. Current reports indicate tumors recurrence rate after IRE av...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08485
更新日期：2015-02-16 00:00:00
abstract：:In this paper, the effect of binder decay rather than a change in the pigments on the blurring of ancient wall paintings was researched. The simulated wall paintings were prepared by brushing an aqueous solution containing gelatine and ochre grains on the surface of cylindrical compressed soil samples. Then, the dried...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78117-4
更新日期：2020-12-03 00:00:00
abstract：:Screening programs for lung cancer aim to allow diagnosis at the early stage, and therefore the decline in mortality rates. Thus, the aim of this retrospective cohort study was to the comparison of screened and non-screened lung cancer in terms of lung cancer characteristics, overdiagnosis and survival rate. A retrosp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56025-6
更新日期：2019-12-18 00:00:00
abstract：:Up to 40% of congenital diseases present disturbances of brain and craniofacial development resulting in simultaneous alterations of both systems. Currently, the best available method to preclinically visualize the brain and the bones simultaneously is to co-register micro-magnetic resonance (µMR) and micro-computed t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75720-3
更新日期：2020-10-30 00:00:00
abstract：:In the developing central nervous system (CNS), oligodendrocyte precursor cells (OPCs) migrate along blood vessels and are widely distributed in the CNS. Meanwhile, OPCs require survival factors from the extracellular microenvironment. In other tissues, laminins, heterotrimetric (αβγ) extracellular matrix proteins, pr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56488-7
更新日期：2019-12-27 00:00:00
abstract：:Voice disorder such as vocal fatigue is a common and complex multifaceted clinical problem that presents a significant impact on quality of life. In this study, the functional near-infrared diffuse optical technique (fNIRS-DOT) was proposed as a novel approach for human vocal cords oxidative metabolism detection and a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16807-2
更新日期：2017-12-05 00:00:00
abstract：:Arbuscular mycorrhizal fungi (AMF) can be beneficial for improving restoration of radioactive-cesium (137Cs)-contaminated soils through soil remediation. However, there has been no information on species diversity and the composition of AMF communities in 137Cs-contaminated soil after the Fukushima-Daiichi Nuclear Pow...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44665-7
更新日期：2019-06-03 00:00:00
abstract：:The circadian clock confers daily rhythmicity on many biochemical and physiological functions and its disruption is associated with increased risks of developing obesity, diabetes, heart disease and cancer. Although, there are studies on the role of Bmal1 in carcinogenesis using germline, conditional or tissue-specifi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34433-4
更新日期：2018-10-30 00:00:00
abstract：:Alignment-free methods, in which shared properties of sub-sequences (e.g. identity or match length) are extracted and used to compute a distance matrix, have recently been explored for phylogenetic inference. However, the scalability and robustness of these methods to key evolutionary processes remain to be investigat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06504
更新日期：2014-09-30 00:00:00
abstract：:Viral infection triggers a series of signaling cascades, which converge to activate the transcription factors nuclear factor-κB (NF-κB) and interferon regulatory factor 3 (IRF3), thereby inducing the transcription of type I interferons (IFNs). Although not fully characterized, these innate antiviral responses are fine...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11220
更新日期：2015-06-10 00:00:00
abstract：:Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S. meningococcal isolates (N = 201) from 15 epidemiologically defined outbreaks (2009-2015) along with temporally and geographic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33622-5
更新日期：2018-10-25 00:00:00
abstract：:Polystyrene sulfonate (PSS), a strong polyelectrolyte, was used to prepare red photoluminescent PSS-penicillamine (PA) copper (Cu) nanoclusters (NC) aggregates, which displayed high selectivity and sensitivity to the detection of hydrogen sulfide (H2S). The size of the PSS-PA-Cu NC aggregates could be readily controll...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24882
更新日期：2016-04-26 00:00:00
abstract：:Patients with Type-2 Diabetes Mellitus (T2DM) have a considerably higher risk of developing mild cognitive impairment (MCI) and dementia. The initial symptoms are very insidious at onset. We investigated the alterations in spontaneous brain activity and network connectivity through regional homogeneity (ReHo) and grap...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76495-3
更新日期：2020-12-04 00:00:00
abstract：:Factor induced reprogramming of fibroblasts is an orchestrated but inefficient process. At the epigenetic level, it results in drastic chromatin changes to erase the existing somatic "memory" and to establish the pluripotent state. Accordingly, alterations of chromatin regulators including Ezh2 influence iPSC generati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08229
更新日期：2015-02-04 00:00:00
abstract：:In recent years, a growing amount of research has begun to focus on the oral microbiome due to its links with health and systemic disease. The oral microbiome has numerous advantages that make it particularly useful for clinical studies, including non-invasive collection, temporal stability, and lower complexity relat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11427-2
更新日期：2017-09-08 00:00:00
