Role of Histidine 547 of Human Dopamine Transporter in Molecular Interaction with HIV-1 Tat and Dopamine Uptake.

abstract：:The fabrication of Ru nanostructures by focused electron beam induced deposition (FEBID) requires suitable precursor molecules and processes to obtain the pure metal. So far this is problematic because established organometallic Ru precursors contain large organic ligands, such as cyclopentadienyl anions, that tend to...

journal_title：Scientific reports

authors： Rohdenburg M,Boeckers H,Brewer CR,McElwee-White L,Swiderek P

更新日期：2020-07-02 00:00:00

abstract：:Ocimum is one of the most revered medicinally useful plants which have various species. Each of the species is distinct in terms of metabolite composition as well as the medicinal property. Some basil types are used more often as an aromatic and flavoring ingredient. It would be informative to know relatedness among t...

journal_title：Scientific reports

authors： Rastogi S,Shah S,Kumar R,Kumar A,Shasany AK

更新日期：2020-03-23 00:00:00

abstract：:In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intraocular pressures ar...

journal_title：Scientific reports

authors： Hasegawa T,Ikeda HO,Iwai S,Sasaoka N,Kakizuka A,Tsujikawa A

更新日期：2020-12-10 00:00:00

abstract：:The formation of snow-dirt sludge (SDS) via the mixing of snow and surface-deposited sediment by vehicles and pedestrians is one of the least studied sedimentation processes in urban areas. The aim of this study was to analyse the material, mineral, particle size, and chemical compositions of the SDS solid phase. The ...

journal_title：Scientific reports

authors： Seleznev A,Yarmoshenko I,Malinovsky G,Ilgasheva E,Baglaeva E,Ryanskaya A,Kiseleva D,Gulyaeva T

更新日期：2019-11-21 00:00:00

abstract：:Metastatic colorectal cancer is the fourth most common cause of cancer death. Current options in palliation such as hyperthermic intraperitoneal chemotherapy (HIPEC) present severe side effects. Recent research efforts suggested the therapeutic use of oxidant-enriched liquid using cold physical plasma. To investigate ...

journal_title：Scientific reports

authors： Freund E,Liedtke KR,van der Linde J,Metelmann HR,Heidecke CD,Partecke LI,Bekeschus S

更新日期：2019-01-24 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with aggregation of TAR DNA-binding protein-43 (TDP-43) in neuronal cells and manifests as motor neuron dysfunction &muscle atrophy. The carboxyl-terminal prion-like domain of TDP-43 can aggregate in vitro into toxic β-sheet rich amylo...

journal_title：Scientific reports

authors： Prasad A,Raju G,Sivalingam V,Girdhar A,Verma M,Vats A,Taneja V,Prabusankar G,Patel BK

更新日期：2016-12-21 00:00:00

abstract：:Viruses induce double-stranded RNA (dsRNA) in the host cells. The mammalian system has developed dsRNA-dependent recognition receptors such as RLRs that recognize the long stretches of dsRNA as PAMPs to activate interferon-mediated antiviral pathways and apoptosis in severe infection. Here we report an efficient antiv...

journal_title：Scientific reports

authors： Wang W,Wang WH,Azadzoi KM,Su N,Dai P,Sun J,Wang Q,Liang P,Zhang W,Lei X,Yan Z,Yang JH

更新日期：2016-03-03 00:00:00

abstract：:Ebola virus disease (EVD) is a contagious, severe and often lethal form of hemorrhagic fever in humans. The association of EVD outbreaks with forest clearance has been suggested previously but many aspects remained uncharacterized. We used remote sensing techniques to investigate the association between deforestation ...

journal_title：Scientific reports

authors： Olivero J,Fa JE,Real R,Márquez AL,Farfán MA,Vargas JM,Gaveau D,Salim MA,Park D,Suter J,King S,Leendertz SA,Sheil D,Nasi R

更新日期：2017-10-30 00:00:00

abstract：:Dyslipidemia in pregnancy are associated with risk of adverse outcomes. As an adverse pregnancy outcome, small-for-gestational-age has been extensively studied in Western countries. However, similar studies have rarely been conducted in Asian countries. Data were derived from 5695 pairs of non-diabetic mothers and neo...

journal_title：Scientific reports

authors： Chen Q,Chen H,Xi F,Sagnelli M,Zhao B,Chen Y,Yang M,Xu D,Jiang Y,Chen G,Luo Q

更新日期：2020-11-16 00:00:00

abstract：:Free carriers, polarons (P), in conjugated polymers play a key role in the performance of optoelectronic devices. Here, we present solid evidence that P can be predominantly generated from polaron pairs (PP) in a poly(3-hexylthiophene) (P3HT) film under zero electric field. P formation from PP strongly depends on temp...

journal_title：Scientific reports

authors： Ogata Y,Kawaguchi D,Tanaka K

更新日期：2015-02-13 00:00:00

abstract：:The current standard treatment for ovarian cancer is aggressive surgery followed by platinum-based combination chemotherapy. Recurrence and chemotherapeutic drug resistance are the two main factors that account for the high mortality of most ovarian cancers. Liposomal doxorubicin is primarily used for the treatment of...

journal_title：Scientific reports

authors： Li S,Cao J,Zhang W,Zhang F,Ni G,Luo Q,Wang M,Tao X,Xia H

更新日期：2016-11-11 00:00:00

abstract：:Neurodegeneration includes acute changes and slow-developing alterations, both of which partly involve common cellular machinery. During neurodegeneration, neuronal processes are impaired along with dysregulated post-translational modifications (PTMs) of cytoskeletal proteins. In neuronal processes, tubulin undergoes ...

journal_title：Scientific reports

authors： Vu HT,Akatsu H,Hashizume Y,Setou M,Ikegami K

更新日期：2017-01-09 00:00:00

abstract：:Mangrove forests are among the most productive and diverse ecosystems on the planet, despite limited nitrogen (N) availability. Under such conditions, animal-microbe associations (holobionts) are often key to ecosystem functioning. Here, we investigated the role of fiddler crabs and their carapace-associated microbial...

journal_title：Scientific reports

authors： Zilius M,Bonaglia S,Broman E,Chiozzini VG,Samuiloviene A,Nascimento FJA,Cardini U,Bartoli M

更新日期：2020-08-18 00:00:00

abstract：:Rapid histopathological evaluation of fresh, unfixed human tissue using optical sectioning microscopy would have applications to intraoperative surgical margin assessment. Microscopy with ultraviolet surface excitation (MUSE) is a low-cost optical sectioning technique using ultraviolet illumination which limits fluore...

journal_title：Scientific reports

authors： Yoshitake T,Giacomelli MG,Quintana LM,Vardeh H,Cahill LC,Faulkner-Jones BE,Connolly JL,Do D,Fujimoto JG

更新日期：2018-03-14 00:00:00

abstract：:The striped venus (Chamelea gallina) is an important economic resource in the Mediterranean Basin; this species has exhibited a strong quantitative decline in the Adriatic Sea. The aim of this work was to provide a comprehensive view of the biological status of C. gallina to elucidate the bioecological characteristics...

journal_title：Scientific reports

authors： Carducci F,Biscotti MA,Trucchi E,Giuliani ME,Gorbi S,Coluccelli A,Barucca M,Canapa A

更新日期：2020-11-05 00:00:00

abstract：:Laryngeal squamous cell carcinoma is a major medical problem worldwide. Although our understanding of genetic changes and their consequences in laryngeal cancer has opened new therapeutic pathways over the years, the diagnostic as well as treatment options still need to be improved. In our previous study, we identifie...

journal_title：Scientific reports

authors： Kostrzewska-Poczekaj M,Bednarek K,Jarmuz-Szymczak M,Bodnar M,Filas V,Marszalek A,Bartochowska A,Grenman R,Kiwerska K,Szyfter K,Giefing M

更新日期：2020-01-08 00:00:00

abstract：:Haber-Bosch nitrogen (N) has been increasingly used in industrial products, e.g., nylon, besides fertilizer. Massive numbers of species of industrial reactive N (Nr) have emerged and produced definite consequences but receive little notice. Based on a comprehensive inventory, we show that (1) the industrial N flux has...

journal_title：Scientific reports

authors： Gu B,Chang J,Min Y,Ge Y,Zhu Q,Galloway JN,Peng C

更新日期：2013-01-01 00:00:00

abstract：:During bacterial infections, damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) activate immune cells. Here, we investigated whether plasma and sputum levels of High Mobility Group Box 1 (HMGB1), a prototypic DAMP, are associated with disease severity and aetiology in commu...

journal_title：Scientific reports

authors： Alpkvist H,Athlin S,Mölling P,Norrby-Teglund A,Strålin K

更新日期：2018-09-07 00:00:00

abstract：:We study the dynamics of an ultrafast single photon pulse in a one-dimensional waveguide two-point coupled with a Jaynes-Cummings system. We find that for any single photon input the transmissivity depends periodically on the separation between the two coupling points. For a pulse containing many plane wave components...

journal_title：Scientific reports

authors： Wang Y,Zhang Y,Zhang Q,Zou B,Schwingenschlogl U

更新日期：2016-09-22 00:00:00

abstract：:In this report, we demonstrate mid-infrared dual-waveband (i.e., ~3 μm and ~2 μm) pulses from a cascaded gain-switched Ho3+-doped ZBLAN fiber laser by the use of hybrid pumping of 1150 nm CW and pulse LDs for the first time. Stable ~3 μm gain-switched pulses with the maximum output power 262.14 mW and shortest pulse d...

journal_title：Scientific reports

authors： Luo H,Li J,Zhu C,Lai X,Hai Y,Liu Y

更新日期：2017-12-04 00:00:00

abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...

journal_title：Scientific reports

authors： You Y,Ramachandra SG,Jin T

更新日期：2020-09-08 00:00:00

abstract：:In this work, we analysed processive sliding and breakage of actin filaments at various heavy meromyosin (HMM) densities and ATP concentrations in IVMA. We observed that with addition of ATP solution, the actin filaments fragmented stochastically; we then determined mean length and velocity of surviving actin filament...

journal_title：Scientific reports

authors： Rastogi K,Puliyakodan MS,Pandey V,Nath S,Elangovan R

更新日期：2016-08-24 00:00:00

abstract：:We have investigated the valley Chern number and gapless edge states in wide-gap semiconductor SiC and BN monolayers by using the density functional theory calculations. We found that while SiC monolayer has a non-quantized valley Chern number due to a partial mixing of the Berry curvature peaks pertaining to the oppo...

journal_title：Scientific reports

authors： Lee KW,Lee CE

更新日期：2020-03-19 00:00:00

abstract：:Spontaneous clearance of hepatitis C virus (HCV) occurs in 10-40% of the infections. Specific human leukocyte antigen (HLA) alleles have been identified in associating with HCV clearance. However, data on the association of HLA with the spontaneous clearance of HCV are scarce in the Chinese population. In the current ...

journal_title：Scientific reports

authors： Huang J,Huang K,Xu R,Wang M,Liao Q,Xiong H,Li C,Tang X,Shan Z,Zhang M,Rong X,Nelson K,Fu Y

更新日期：2016-08-11 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:Burkholderia terrae BS001 has previously been found to be able to disperse along with growing fungal hyphae in soil, with the type-3 secretion system having a supportive role in this movement. In this study, we focus on the role of two motility- and adherence-associated appendages, i.e. type-4 pili (T4P) and flagella....

journal_title：Scientific reports

authors： Yang P,Zhang M,van Elsas JD

更新日期：2017-06-07 00:00:00

abstract：:Spatially resolved analysis of uranium (U) isotopes in small volumes of actinide-bearing materials is critical for a variety of technical disciplines, including earth and planetary sciences, environmental monitoring, bioremediation, and the nuclear fuel cycle. However, achieving subnanometer-scale spatial resolution f...

journal_title：Scientific reports

authors： Kautz E,Burkes D,Joshi V,Lavender C,Devaraj A

更新日期：2019-08-23 00:00:00

abstract：:The concept of brain circuit disorders has been proposed for a variety of neuropsychiatric diseases, characterized by pathological disturbances of neuronal networks including changes in oscillatory signaling of re-entrant cortico-subcortical loops in the basal ganglia system. Parts of this circuitry play a pivotal rol...

journal_title：Scientific reports

authors： Maurer L,Tang H,Haumesser JK,Altschüler J,Kühn AA,Spranger J,van Riesen C

更新日期：2017-11-14 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ezewudo M,Borens A,Chiner-Oms Á,Miotto P,Chindelevitch L,Starks AM,Hanna D,Liwski R,Zignol M,Gilpin C,Niemann S,Kohl TA,Warren RM,Crook D,Gagneux S,Hoffner S,Rodrigues C,Comas I,Engelthaler DM,Alland D,Rigouts L,

更新日期：2020-02-21 00:00:00

abstract：:A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly correlated with levels of resistance and increased dramatically following insecticide selection. However, it is unclear whether this is unique to...

journal_title：Scientific reports

authors： Li T,Zhang L,Reid WR,Xu Q,Dong K,Liu N

更新日期：2012-01-01 00:00:00