Abstract：
:A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly correlated with levels of resistance and increased dramatically following insecticide selection. However, it is unclear whether this is unique to this specific resistant population or is a common mechanism in field mosquito populations in response to insecticide pressure. The current study therefore further characterized these mutations and their combinations in other field and permethrin selected Culex mosquitoes, finding that the co-existence of all 9 mutations was indeed correlated with the high levels of permethrin resistance in mosquitoes. Comparison of mutation combinations revealed several common mutation combinations presented across different field and permethrin selected populations in response to high levels of insecticide resistance, demonstrating that the co-existence of multiple mutations is a common event in response to insecticide resistance across different Cx. quinquefasciatus mosquito populations.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Li T,Zhang L,Reid WR,Xu Q,Dong K,Liu Ndoi
10.1038/srep00781subject
Has Abstractpub_date
2012-01-01 00:00:00pages
781issn
2045-2322journal_volume
2pub_type
杂志文章abstract：:Barley (Hordeum vulgare L.) produces five leucine-derived hydroxynitrile glucosides, potentially involved in alleviating pathogen and environmental stresses. These compounds include the cyanogenic glucoside epiheterodendrin. The biosynthetic genes are clustered. Total hydroxynitrile glucoside contents were previously ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41884-w
更新日期：2019-04-05 00:00:00
abstract：:Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding of the prion protein. Variants such as M142, D145, S146, H154, Q211, and K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed to identify polymorphisms in the Afar and Arsi-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63874-z
更新日期：2020-04-24 00:00:00
abstract：:Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic outputs-the efficacy of the synapses-plays a principal role in all aspects of hi...
journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2019-01-24 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2018-10-18 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50501-9
更新日期：2019-10-01 00:00:00
abstract：:The blood-based diagnosis has a potential to provide an alternative approach for easy diagnosis of Alzheimer's disease (AD) with less invasiveness and low-cost. However, present blood-based AD diagnosis mainly focuses on measuring the plasma Aβ level because no other biomarkers are found to possess evident transport m...
journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2019-03-06 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-01-25 00:00:00
abstract：:Magnesium (Mg) is a lightweight metal with applications in transportation and sustainable battery technologies, but its current production through ore reduction using the conventional Pidgeon process emits large amounts of CO2 and particulate matter (PM2.5). In this work, a novel Pidgeon process driven by microwaves h...
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pub_type： 杂志文章
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更新日期：2017-04-12 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2018-01-12 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2018-01-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-10-24 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-08-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-03-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-06-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2020-11-30 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-21992-9
更新日期：2018-02-23 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-06-29 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章,多中心研究
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更新日期：2018-10-12 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-01-29 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2018-07-13 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-09-05 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45473
更新日期：2017-04-05 00:00:00
abstract：:Sustainable wastewater treatment has been attracting increasing attentions over the past decades. However, the production of nitrous oxide (N2O), a potent GHG, from the energy-efficient granule-based autotrophic nitrogen removal is largely unknown. This study applied a previously established N2O model, which incorpora...
journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-04-03 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep40037. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/srep46991
更新日期：2018-05-22 00:00:00
