Bony ankylosis of the facet joint of the cervical spine in rheumatoid arthritis: Its characteristics and relationship to the clinical findings.

abstract：:A 52-year-old woman with a 6-year history of systemic lupus erythematosus (SLE) developed acute abdominal pain, nausea, vomiting, and diarrhea accompanied by hypocomplementemia. Herpes simplex virus (HSV) esophagitis and lupus enteritis were diagnosed on the basis of the results of endoscopic and histological examinat...

journal_title：Modern rheumatology

authors： Wakui H,Togashi M,Omokawa A,Okuyama S,Masai R,Komatsuda A,Ogasawara H,Sawada K

更新日期：2010-02-01 00:00:00

abstract：:This report documents the results of a study performed to examine clinical use of mizoribine (MZR), using data from a large-scale prospective cohort study, IORRA (Institute of Rheumatology Rheumatoid Arthritis). The number of patients with RA entered in this study from October 2000 through October 2003 was 6238. Three...

journal_title：Modern rheumatology

authors： Tanaka E,Inoue E,Kawaguchi Y,Tomatsu T,Yamanaka H,Hara M,Kamatani N

更新日期：2006-01-01 00:00:00

abstract：:Abstract Twenty-six patients with systemic lupus erythematosus (SLE) showing systemic lupus activity measure (SLAM) and SLE disease activity index (SLEDAI) scores ≤2, as well as a lower C4 concentration than the mean C4 levels of healthy controls, were selected to evaluate the C4 levels of SLE patients in remission. S...

journal_title：Modern rheumatology

authors： Yasuda M,Suenaga Y,Nishimukai H,Nobunaga M

更新日期：2002-09-01 00:00:00

abstract：:Abstract The human major histocompatibility complex (MHC) class I gene HLA-B27 bears a striking association with ankylosing spondylitis and related spondyloarthropathies. This association transcends all ethnic and geographical boundaries. The primary function of HLA-B27 as an MHC class I protein is to form a complex w...

journal_title：Modern rheumatology

authors： Mehra NK,Kanga U

更新日期：2001-12-01 00:00:00

abstract：:A 68-year-old Japanese male presented with atrophic erythematous white lesions with peripheral dark reddish rims on his back. Multiple ulcers were detected from his stomach to his large intestine using endoscopy. Although the patient was given high doses of a steroid, aspirin, dipyridamole, and intravenous immunoglobu...

journal_title：Modern rheumatology

authors： Umemura M,Miwa Y,Yanai R,Isojima S,Tokunaga T,Tsukamoto H,Takahashi R,Yajima N,Kasama T,Takahashi N,Sueki H,Yamaguchi S,Arai K,Takeuchi Y,Ohike N,Norose T,Yamochi-Onizuka T,Takimoto M

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy of tocilizumab for preventing damage to the joints of systemic juvenile idiopathic arthritis (sJIA) patients, we examined serial radiographs of the hands and large weight-bearing joints of these patients before and after treatment with this agent. METHODS:Nine patients with sJIA recei...

journal_title：Modern rheumatology

authors： Inaba Y,Ozawa R,Aoki C,Imagawa T,Mori M,Hara R,Miyamae T,Saito T,Yokota S

更新日期：2013-07-01 00:00:00

abstract：:Cutaneous polyarteritis nodosa (CPAN) is a form of necrotizing vasculitis of small and medium-sized arteries. It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. We report the clinical case of a 7-year-o...

journal_title：Modern rheumatology

authors： Valor L,Monteagudo I,de la Torre I,Fernández CG,Montoro M,Longo JL,Carreño L

更新日期：2014-07-01 00:00:00

abstract：:To evaluate the efficacy of high-dose leukocytapheresis (LCAP) using a large filter in patients with refractory rheumatoid arthritis (RA), we conducted a multicenter, nonrandomized, open-label clinical study. Thirty patients with highly active RA were treated with high-dose LCAP performed 3-5 sessions at 1-week interv...

journal_title：Modern rheumatology

authors： Eguchi K,Saito K,Kondo M,Hidaka T,Ueki Y,Tanaka Y,LCAP Investigators in Kyushu College of Rheumatology (LIKCR).

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:A nationwide survey was conducted to assess the number of patients, clinical aspects, treatment, and prognosis of adult Still's disease (ASD) in Japan. METHODS:A primary questionnaire was sent to randomly selected medical institutions in order to estimate the number of patients. We sent a secondary question...

journal_title：Modern rheumatology

authors： Asanuma YF,Mimura T,Tsuboi H,Noma H,Miyoshi F,Yamamoto K,Sumida T

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To obtain safety and efficacy data on combination treatment with iguratimod and methotrexate (MTX) in an open-label extension study in patients with active rheumatoid arthritis (RA). METHODS:Following a 28-week, randomized, double-blind trial of adding iguratimod or placebo to stable MTX therapy, patients en...

journal_title：Modern rheumatology

authors： Hara M,Ishiguro N,Katayama K,Kondo M,Sumida T,Mimori T,Soen S,Nagai K,Yamaguchi T,Yamamoto K,Iguratimod-Clinical Study Group.

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:Anti-cytokine therapy is reportedly useful in amyloid A (AA) amyloidosis complicating rheumatic diseases. However, to date no studies have directly compared the utility of tumour necrosis factor (TNF) inhibition to that of interleukin-6. The aim of our retrospective study was to compare the clinical utility ...

journal_title：Modern rheumatology

authors： Okuda Y,Ohnishi M,Matoba K,Jouyama K,Yamada A,Sawada N,Mokuda S,Murata Y,Takasugi K

更新日期：2014-01-01 00:00:00

abstract：:To evaluate the composite disease activity indices for rheumatoid arthritis (RA), we compared disease activities and the changes therein calculated using the Disease Activity Score based on 28 joint counts using erythrocyte sedimentation rate (DAS28-ESR), DAS28-CRP (C-reactive protein), Simplified Disease Activity Ind...

journal_title：Modern rheumatology

authors： Matsui T,Kuga Y,Nishino J,Kaneko A,Eto Y,Tohma S

更新日期：2011-04-01 00:00:00

abstract：: ...

journal_title：Modern rheumatology

authors： Hatta Y,Hasegawa M,Matsushita T,Hamaguchi Y,Fujimoto M,Takehara K

更新日期：2013-04-27 00:00:00

abstract：OBJECTIVE:Increased femoral neck bone mineral density (BMD) in a hip with osteoarthritis (OA) has been previously reported, however, it is possible that increased BMD at sites other than the hip joint is influenced by the disease process of OA. Therefore, we measured BMD at locations different from the hip joint and de...

journal_title：Modern rheumatology

authors： Okano K,Ito M,Aoyagi K,Osaki M,Enomoto H,Yamaguchi K

更新日期：2014-03-01 00:00:00

abstract：:Recently, more than ten cases of thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome or Castleman-Kojima disease exhibiting such symptoms as thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly have been reported in Japan. We have found two cases of TAFRO syndrome...

journal_title：Modern rheumatology

authors： Kawashima M,Usui T,Okada H,Mori I,Yamauchi M,Ikeda T,Kajita K,Kito Y,Miyazaki T,Fujioka K,Ishizuka T,Morita H

更新日期：2017-11-01 00:00:00

abstract：:Abstract We report the case of a 52-year-old man with Wegener's granulomatosis complicated with seropneumothorax. Pneumothorax or seropneumothorax has previously been reported as a rare complication of Wegener's granulomatosis. The patient was successfully treated with prednisolone and cyclophosphamide, and seropneumo...

journal_title：Modern rheumatology

authors： Shimizu T,Ohara T,Ito S,Nakano M,Tsutsui N,Sato T,Suzuki E,Gejyo F

更新日期：2003-06-01 00:00:00

abstract：:Abstract Little is known about the specific effects of the ultra-high molecular weight polyethylene (UHMWP) debris that is obtained from human interface membranes after revision for a failed total hip arthroplasty. This paper reports the effects of retrieved polyethylene particles on human monocyte/macrophages (M/M). ...

journal_title：Modern rheumatology

authors： Chiba J,Inoue K

更新日期：2000-03-01 00:00:00

abstract：:A 61-year-old woman was admitted for long-lasting fever and recurrent opportunistic infections during the treatment of SLE. She had been diagnosed as SLE and type-IV nephritis based on a renal biopsy and serological findings. A colonoscopy and liver biopsy revealed disseminated Mycobacterium avium complex infection. H...

journal_title：Modern rheumatology

authors： Ochi S,Kato S,Nakamura-Uchiyama F,Ohnishi K,Saito Y

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the improvement of health status in patients with rheumatoid arthritis (RA) treated with tocilizumab. METHODS:Thirty-nine patients were treated with 8 mg/kg tocilizumab every 4 weeks for 24 weeks. Disease activity was assessed by Clinical Disease Activity Index (CDAI) and Simplified Disease Activ...

journal_title：Modern rheumatology

authors： Fusama M,Nakahara H,Hamano Y,Nishide M,Kawamoto K,Hosokawa T,Nozato S,Higa S,Igarashi T,Takeuchi E,Kuroiwa T,Shimaoka Y,Yukioka M,Miura Y,Higashi K,Kuritani T,Maeda K

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:Cryopyrin-associated periodic syndrome (CAPS) is caused by unrestricted IL-1β release due to mutation of the gene coding NLRP3. This study aimed to clarify whether NLRP3-related IL-1β release is dependent on the NF-κB pathway. METHODS:Peripheral blood mononuclear cells (PBMCs) from healthy subjects or patie...

journal_title：Modern rheumatology

authors： Shimogaki S,Ito S,Komatsu S,Koike R,Miyasaka N,Umezawa K,Kubota T

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:Evaluate the association between the multi-biomarker disease activity (MBDA) score and radiographic progression in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF)-α inhibitors. METHODS:Change (Δ) in modified total Sharp score (mTSS) over 52 weeks and disease activity scores w...

journal_title：Modern rheumatology

authors： Hirata S,Li W,Kubo S,Fukuyo S,Mizuno Y,Hanami K,Sawamukai N,Yamaoka K,Saito K,Defranoux NA,Tanaka Y

更新日期：2016-11-01 00:00:00

abstract：:Pneumatosis cystoides intestinalis (PCI), which is characterized by the presence of multiple gas-filled mucosal, submucosal, or subserosal cysts located throughout the colon and/or small intestine, is an unusual complication of systemic lupus erythematosus (SLE). We report a case of a 33-year-old woman with a 5-year h...

journal_title：Modern rheumatology

authors： Yamaguchi Y,Ohno S,Yamazaki S,Ideguchi H,Shirai A,Takeno M,Ishigatsubo Y

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To assess the long-term safety, immunogenicity, and efficacy of subcutaneous (SC) abatacept in combination with methotrexate (MTX) in Japanese patients with rheumatoid arthritis who were MTX inadequate responders, in a long-term extension (LTE) to a double-dummy, double-blind study (NCT01001832). METHODS:Pat...

journal_title：Modern rheumatology

authors： Amano K,Matsubara T,Tanaka T,Inoue H,Iwahashi M,Kanamono T,Nakano T,Uchimura S,Izumihara T,Yamazaki A,Karyekar CS,Takeuchi T,Japan Abatacept Study Group.

更新日期：2015-09-01 00:00:00

abstract：:A 20-year-old man presented with recurrent hemoptysis for seven months. A small subpleural nodule in his right lower lobe was found and excised surgically. Based on the presence of antiphospholipid antibodies (aPL) and vascular wall hypertrophy without vasculitis or an intraluminal thrombus, nonthrombotic proliferativ...

journal_title：Modern rheumatology

authors： Lee JS,Kim H,Lee EB,Song YW,Park JK

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To evaluate joint inflammation using 3-T MRI in rheumatoid arthritis (RA) patients treated with conventional disease modifying anti-rheumatic drugs (cDMARDs) as compared to inhibitors for tumor necrosis factor α (TNFi) over 12 months. METHODS:Prospective epidemiologic clinical pilot study using the RA MRI s...

journal_title：Modern rheumatology

authors： Oleszowsky M,Willinek W,Marinova M,Seidel MF

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:To assess gout and asymptomatic hyperuricemia in Japan and review treatment conditions. METHODS:This retrospective cross-sectional study analyzed the prevalence of hyperuricemia and gout, and characteristics and treatment of patients with those conditions, using Japanese health insurance claims and medical ...

journal_title：Modern rheumatology

authors： Koto R,Nakajima A,Horiuchi H,Yamanaka H

更新日期：2021-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a very heterogeneous systemic autoimmune disease, in which autoantibody synthesis against nuclear constituents is the main immunological characteristic. These autoantibodies underwent affinity maturation and isotype switching. Additionally, T-cell tolerance against nuclear autoant...

journal_title：Modern rheumatology

authors： Grossmayer GE,Munoz LE,Gaipl US,Franz S,Sheriff A,Voll RE,Kalden JR,Herrmann M

更新日期：2005-01-01 00:00:00

abstract：:For surgical treatment of rheumatoid wrists, we have routinely selected the Sauve-Kapandji (S-K) procedure or the Darrach procedure based on predetermined indications. In this study, we conducted a retrospective radiographic comparative evaluation of the changes in the carpus after the two procedures. The S-K group an...

journal_title：Modern rheumatology

authors： Kobayashi A,Futami T,Tadano I,Fujita M,Watanabe T,Moriguchi T

更新日期：2005-01-01 00:00:00

abstract：:We examined the efficacy and safety of autologous transplantation of bone-marrow-derived cells in patients with intractable ulcers caused by systemic sclerosis. Eight patients with ulcers resistant to treatment were enrolled. Bone marrow cells were gathered from the bilateral iliac crests with multiple repositioning b...

journal_title：Modern rheumatology

authors： Ishigatsubo Y,Ihata A,Kobayashi H,Hama M,Kirino Y,Ueda A,Takeno M,Shirai A,Ohno S

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to develop clinical practice guideline (CPG) for Sjögren's syndrome (SS) based on recently available clinical and therapeutic evidences. METHODS:The CPG committee for SS was organized by the Research Team for Autoimmune Diseases, Research Program for Intractable Disease of the...

journal_title：Modern rheumatology

authors： Sumida T,Azuma N,Moriyama M,Takahashi H,Asashima H,Honda F,Abe S,Ono Y,Hirota T,Hirata S,Tanaka Y,Shimizu T,Nakamura H,Kawakami A,Sano H,Ogawa Y,Tsubota K,Ryo K,Saito I,Tanaka A,Nakamura S,Takamura E,Tanaka M

更新日期：2018-05-01 00:00:00