Escherichia coli strain Nissle 1917-from bench to bedside and back: history of a special Escherichia coli strain with probiotic properties.

Abstract:

:Among the gram-negative microorganisms with probiotic properties, Escherichia coli strain Nissle 1917 (briefly EcN) is probably the most intensively investigated bacterial strain today. Since nearly 100 years, the EcN strain is used as the active pharmaceutical ingredient in a licensed medicinal product that is distributed in Germany and several other countries. Over the last few decades, novel probiotic activities have been detected, which taken together are specific of this versatile E. coli strain. This review gives a short overview on the discovery and history of the EcN strain.

journal_name

FEMS Microbiol Lett

authors

Sonnenborn U

doi

10.1093/femsle/fnw212

subject

Has Abstract

pub_date

2016-10-01 00:00:00

issue

19

eissn

0378-1097

issn

1574-6968

pii

fnw212

journal_volume

363

pub_type

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