Abstract:
:Legionella pneumophila is a pathogenic bacterium found in freshwater environments that is responsible for pneumonia. People become infected through inhalation of contaminated droplets from water devices, such as cooling towers and showers. It is important to find new treatments that decrease the development of Legionella. We found a Staphylococcus warneri strain that inhibits Legionella growth. This activity is due to a molecule secreted by S. warneri. This molecule displayed a high heat-stability and its activity was lost after protease treatments, suggesting that it might be a bacteriocin. Its purification led us to conclude that this anti-Legionella molecule is an highly hydrophobic peptide. It has an original and very specific spectrum of activity, directed only toward the Legionella genus. This is the first description of an antibacterial peptide active against Legionella.
journal_name
FEMS Microbiol Lettjournal_title
FEMS microbiology lettersauthors
Héchard Y,Ferraz S,Bruneteau E,Steinert M,Berjeaud JMdoi
10.1016/j.femsle.2005.03.046keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
19-23issue
1eissn
0378-1097issn
1574-6968pii
S0378-1097(05)00206-5journal_volume
252pub_type
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