ZCF32, a fungus specific Zn(II)2 Cys6 transcription factor, is a repressor of the biofilm development in the human pathogen Candida albicans.

abstract：:Parkinson's disease (PD) is a degenerative disorder that affects the central nervous system. PD-related alterations in structural and functional neuroimaging have not been fully explored. This study explored multi-modal PD neuroimaging and its application for predicting clinical scores on the Movement Disorder Society...

journal_title：Scientific reports

authors： Son SJ,Kim M,Park H

更新日期：2016-11-30 00:00:00

abstract：:Ocular involvement in leukemia is considered rare. Ocular symptoms can be the presenting signs of leukemia, they can appear after diagnosis has been established, or they can be the first manifestation of a relapse after remission. We report, to the best of our knowledge for the first time, the ocular manifestation of ...

journal_title：Scientific reports

authors： Vishnevskia-Dai V,Sella King S,Lekach R,Fabian ID,Zloto O

更新日期：2020-02-06 00:00:00

abstract：:Sirtuin 1 (SIRT1) is involved in both aging and circadian-clock regulation, yet the link between the two processes in relation to SIRT1 function is not clear. Using Sirt1-deficient mice, we found that Sirt1 and Period 2 (Per2) constitute a reciprocal negative regulation loop that plays important roles in modulating he...

journal_title：Scientific reports

authors： Wang RH,Zhao T,Cui K,Hu G,Chen Q,Chen W,Wang XW,Soto-Gutierrez A,Zhao K,Deng CX

更新日期：2016-06-27 00:00:00

abstract：:By combining the two basic deformation mechanisms for auxetic open-cell metamaterials, re-entrant angle and chirality, new hybrid chiral mechanical metamaterials are designed and fabricated via a multi-material 3D printer. Results from mechanical experiments on the 3D printed prototypes and systematic Finite Element (...

journal_title：Scientific reports

authors： Jiang Y,Li Y

更新日期：2018-02-05 00:00:00

abstract：:In a 250-kyr transient simulation of the Community Earth System Model (CESM), we identified a precessional forced seesaw of the summer middle-upper tropospheric eddy temperature between Asia and the North Pacific as the paleo-APO (Asian-Pacific oscillation). The paleo-APO variability is out of phase with the precessio...

journal_title：Scientific reports

authors： Wang Y,Jian Z,Zhao P,Xiao D,Chen J

更新日期：2016-07-06 00:00:00

abstract：:Microorganisms are key components for plant biomass breakdown within rumen environments. Fibrobacter succinogenes have been identified as being active and dominant cellulolytic members of the rumen. In this study, F. succinogenes type strain S85 was adapted for steady state growth in continuous culture at pH 5.75 and ...

journal_title：Scientific reports

authors： Wu CW,Spike T,Klingeman DM,Rodriguez M,Bremer VR,Brown SD

更新日期：2017-05-23 00:00:00

abstract：:Due to limited availability of pharmacological therapies, triple-negative breast cancer (TNBC) is the subtype with worst outcome. We hypothesised that 2-Deoxy-D-Glucose (2-DG), a glucose analogue, may hold potential as a therapy for particularly aggressive TNBC. We investigated 2-DG's effects on TNBC cell line variant...

journal_title：Scientific reports

authors： O'Neill S,Porter RK,McNamee N,Martinez VG,O'Driscoll L

更新日期：2019-03-07 00:00:00

abstract：:Molecular dynamics (MD) simulations lasting 500 ns were performed in explicit water to investigate the effect of polarization on the binding of ligands to human α-thrombin based on the standard nonpolarizable AMBER force field and the quantum-derived polarized protein-specific charge (PPC). The PPC includes the electr...

journal_title：Scientific reports

authors： Duan LL,Feng GQ,Zhang QG

更新日期：2016-08-10 00:00:00

abstract：:Hysteresis, which is the history dependence of physical systems, is one of the most important topics in physics. Interestingly, bi-stability of plasma with a huge hysteresis loop has been observed in inductive plasma discharges. Despite long plasma research, how this plasma hysteresis occurs remains an unresolved ques...

journal_title：Scientific reports

authors： Lee HC,Chung CW

更新日期：2015-10-20 00:00:00

abstract：:We examined how plant-pollinator interactions were affected by time since habitat restoration and landscape connectivity by comparing plant-pollinator networks in restored, abandoned and continuously grazed semi-natural pastures in south-central Sweden. We measured richness of flowering plants and pollinators, and loc...

journal_title：Scientific reports

authors： Noreika N,Bartomeus I,Winsa M,Bommarco R,Öckinger E

更新日期：2019-10-29 00:00:00

abstract：:The effective differentiation between multiple primary lung tumors (MPs) and intrapulmonary metastases (IMs) in patients is imperative to discover the exact disease stage and to select the most appropriate treatment. In this study, the authors was to evaluate the efficacy and validity of large-scale targeted sequencin...

journal_title：Scientific reports

authors： Duan J,Ge M,Peng J,Zhang Y,Yang L,Wang T,Qin T,Yuan R,Zhang Y,Cheng W

更新日期：2020-11-02 00:00:00

abstract：:Genetic alterations identified in adjacent normal appearing tissue in bladder cancer patients are indicative of a field disease. Here we assessed normal urothelium transformation and intra-tumour heterogeneity (ITH) in four patients with bladder cancer. Exome sequencing identified private acquired mutations in a lymph...

journal_title：Scientific reports

authors： Thomsen MBH,Nordentoft I,Lamy P,Vang S,Reinert L,Mapendano CK,Høyer S,Ørntoft TF,Jensen JB,Dyrskjøt L

更新日期：2017-09-15 00:00:00

abstract：:Photomechanical nanocomposites embedded with light-absorbing nanoparticles show promising applications in photoresponsive actuations. Near infrared (nIR)-responsive nanocomposites based photomechanical soft actuators can offer lightweight functional and underexploited entry into soft robotics, active optics, drug deli...

journal_title：Scientific reports

authors： Niu D,Jiang W,Liu H,Zhao T,Lei B,Li Y,Yin L,Shi Y,Chen B,Lu B

更新日期：2016-06-06 00:00:00

abstract：:Understanding drought-tolerance mechanisms and identifying genetic dominance are important for crop improvement. Setaria italica, which is extremely drought-tolerant, has been regarded as a model plant for studying stress biology. Moreover, different genotypes of S. italica have evolved various drought-tolerance/avoid...

journal_title：Scientific reports

authors： Tang S,Li L,Wang Y,Chen Q,Zhang W,Jia G,Zhi H,Zhao B,Diao X

更新日期：2017-08-30 00:00:00

abstract：:Nowadays, there is a growing concern about the environmental impacts of colored wastewater. Thus, the present work aims the synthesis, characterization and determination of photocatalytic activity of iron oxide (Fe2O3) nanocatalyst, evaluating the effect of hybridization with titanium (TiNPs-Fe2O3) and silver (AgNPs-F...

journal_title：Scientific reports

authors： Muraro PCL,Mortari SR,Vizzotto BS,Chuy G,Dos Santos C,Brum LFW,da Silva WL

更新日期：2020-02-20 00:00:00

abstract：:Male moths use species-specific sex pheromones to identify and orientate toward conspecific females. Odorant receptors (ORs) for sex pheromone substances have been identified as sex pheromone receptors in various moth species. However, direct in vivo evidence linking the functional role of these ORs with behavioural r...

journal_title：Scientific reports

authors： Sakurai T,Mitsuno H,Mikami A,Uchino K,Tabuchi M,Zhang F,Sezutsu H,Kanzaki R

更新日期：2015-06-05 00:00:00

abstract：:Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential for the viral lifecycle. BM2 is a functional analog of AM2 but shares only 24% sequence identity for the transmembrane (TM) domain. The structure and function o...

journal_title：Scientific reports

authors： Mandala VS,Liao SY,Gelenter MD,Hong M

更新日期：2019-03-06 00:00:00

abstract：:In the interfacial superconductor Bi2Te3/Fe1+yTe, two dimensional superconductivity occurs in direct vicinity to the surface state of a topological insulator. If this state were to become involved in superconductivity, under certain conditions a topological superconducting state could be formed, which is of high inter...

journal_title：Scientific reports

authors： He MQ,Shen JY,Petrović AP,He QL,Liu HC,Zheng Y,Wong CH,Chen QH,Wang JN,Law KT,Sou IK,Lortz R

更新日期：2016-09-02 00:00:00

abstract：:Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including microRNAs (miRNAs)...

journal_title：Scientific reports

authors： Morhayim J,van de Peppel J,Braakman E,Rombouts EW,Ter Borg MN,Dudakovic A,Chiba H,van der Eerden BC,Raaijmakers MH,van Wijnen AJ,Cornelissen JJ,van Leeuwen JP

更新日期：2016-09-02 00:00:00

abstract：:Bats are an important reservoir for zoonotic viruses. To date, only three RVA strains have been reported in bats in Kenya and China. In the current study we investigated the genetic diversity of RVAs in fecal samples from 87 straw-colored fruit bats living in close contact with humans in Cameroon using viral metagenom...

journal_title：Scientific reports

authors： Yinda CK,Zeller M,Conceição-Neto N,Maes P,Deboutte W,Beller L,Heylen E,Ghogomu SM,Van Ranst M,Matthijnssens J

更新日期：2016-09-26 00:00:00

abstract：:Warburg effect or aerobic glycolysis provides selective growth advantage to aggressive cancers. However, targeting oncogenic regulators of Warburg effect has always been challenging owing to the wide spectrum of roles of these molecules in multitude of cells. In this study, we present ADP-dependent glucokinase (ADPGK)...

journal_title：Scientific reports

authors： Tandon A,Birkenhagen J,Nagalla D,Kölker S,Sauer SW

更新日期：2020-08-12 00:00:00

abstract：:Invasive species are characterized by their ability to colonize new habitats and establish populations away from their native range. In this sense, these plants are expected to have plastic responses to adapt to the environmental pressures during the invasion process. Hence, the role of natural selection is essential ...

journal_title：Scientific reports

authors： Dematteis B,Ferrucci MS,Coulleri JP

更新日期：2020-11-18 00:00:00

abstract：:Given the prevalence of poor adherence to therapy and the biases of self-reporting across healthcare, we hypothesized that an engaging, personalized therapy may improve adherence and treatment outcomes in the home. We tested this hypothesis in the initial indication of amblyopia, a neurodevelopmental disorder for whic...

journal_title：Scientific reports

authors： Xiao S,Gaier ED,Mazow ML,Stout AU,Travers DA,Angjeli E,Wu HC,Binenbaum G,Hunter DG

更新日期：2020-05-20 00:00:00

abstract：:Inhomogeneity in the ground state is an intriguing, emergent phenomenon in magnetism. Recently, it has been observed in the magnetostructural channel of the geometrically frustrated α-NaMnO2, for the first time in the absence of active charge degrees of freedom. Here we report an in-depth numerical and local-probe exp...

journal_title：Scientific reports

authors： Zorko A,Kokalj J,Komelj M,Adamopoulos O,Luetkens H,Arčon D,Lappas A

更新日期：2015-03-19 00:00:00

abstract：:This study was initiated to improve E. coli succinate production by engineering the E. coli global transcription factor, Cra (catabolite repressor/activator). Random mutagenesis libraries were generated through error-prone PCR of cra. After re-screening and mutation site integration, the best mutant strain was Tang154...

journal_title：Scientific reports

authors： Zhu LW,Xia ST,Wei LN,Li HM,Yuan ZP,Tang YJ

更新日期：2016-11-04 00:00:00

abstract：:The seed storage proteins of soybean (Glycine max) are composed mainly of glycinin (11S globulin) and β-conglycinin (7S globulin). The subunits of glycinin (A1aB1b, A1bB2, A2B1a, A3B4, and A5A4B3) are synthesized as a single polypeptide precursor. These precursors are assembled into trimers with a random combination o...

journal_title：Scientific reports

authors： Maruyama N,Matsuoka Y,Yokoyama K,Takagi K,Yamada T,Hasegawa H,Terakawa T,Ishimoto M

更新日期：2018-01-18 00:00:00

abstract：:Cold environments dominate the Earth's biosphere and the resident microorganisms play critical roles in fulfilling global biogeochemical cycles. However, only few studies have examined the molecular basis of thermosensing; an ability that microorganisms must possess in order to respond to environmental temperature and...

journal_title：Scientific reports

authors： Najnin T,Siddiqui KS,Taha T,Elkaid N,Kornfeld G,Curmi PM,Cavicchioli R

更新日期：2016-04-07 00:00:00

abstract：:It has been well established that some Armillaria species are symbionts of Polyporus umbellatus, However, little is known about the evolutionary history of P. umbellatus-Armillaria associations. In this research, we used an analysis based on the strength of the phylogenetic signal to investigate P. umbellatus-Armillar...

journal_title：Scientific reports

authors： Xing X,Men J,Guo S

更新日期：2017-06-26 00:00:00

abstract：:We have engineered the electronic structure at the interface between Cu2O and ZnO nanorods (NRs) array, through adjusting the carrier concentration of Cu2O. The electrodeposition of Cu2O at pH 11 acquired the highest carrier concentration, resulting in the largest interfacial electric field between Cu2O and ZnO, which...

journal_title：Scientific reports

authors： Kang Z,Yan X,Wang Y,Bai Z,Liu Y,Zhang Z,Lin P,Zhang X,Yuan H,Zhang X,Zhang Y

更新日期：2015-01-20 00:00:00

abstract：:We propose the realization of photonic circuits whose dynamics is governed by advanced-retarded differential equations. Beyond their mathematical interest, these photonic configurations enable the implementation of quantum feedback and feedforward without requiring any intermediate measurement. We show how this protoc...

journal_title：Scientific reports

authors： Alvarez-Rodriguez U,Perez-Leija A,Egusquiza IL,Gräfe M,Sanz M,Lamata L,Szameit A,Solano E

更新日期：2017-02-23 00:00:00