Improved adherence and treatment outcomes with an engaging, personalized digital therapeutic in amblyopia.

abstract：:Potassium depletion affects AQP2 expression and the cellular composition of the kidney collecting duct. This, in turn, contributes to the development of a secondary form of nephrogenic diabetes insipidus and hypokalemic nephropathy. Here we show that after 14 days of potassium depletion, the cellular fraction of A-typ...

journal_title：Scientific reports

authors： Iervolino A,Prosperi F,De La Motte LR,Petrillo F,Spagnuolo M,D'Acierno M,Siccardi S,Perna AF,Christensen BM,Frische S,Capasso G,Trepiccione F

更新日期：2020-03-31 00:00:00

abstract：:Human induced pluripotent stem cells (hiPSCs) are expected to be both a revolutionary cell source for regenerative medicine and a powerful tool to investigate the molecular mechanisms underlying human cell development in vitro. In the present study, we tried to elucidate the steroidogenic differentiation processes usi...

journal_title：Scientific reports

authors： Matsuo K,Sone M,Honda-Kohmo K,Toyohara T,Sonoyama T,Taura D,Kojima K,Fukuda Y,Ohno Y,Inoue M,Ohta A,Osafune K,Nakao K,Inagaki N

更新日期：2017-11-09 00:00:00

abstract：:Measurements of volcanic tephra fallout deposits provide useful information about the magnitude and intensity of explosive volcanic eruptions and potential for remobilization of deposits as dangerous volcanic flows. However, gathering information in the vicinity of erupting craters is extremely dangerous, and moreover...

journal_title：Scientific reports

authors： Tanaka HKM

更新日期：2020-09-09 00:00:00

abstract：:Mechanosensitive ion channels are pore-forming transmembrane proteins that allow ions to move down their electrochemical gradient in response to mechanical stimuli. They participate in many plant developmental processes including the maintenance of plastid shape, pollen tube growth, etc. Herein, a total of 11, 10, 6, ...

journal_title：Scientific reports

authors： Kaur A,Taneja M,Tyagi S,Sharma A,Singh K,Upadhyay SK

更新日期：2020-10-06 00:00:00

abstract：:Urothelial cells play essential roles in protection of urine exudation and bacterial invasion at the urothelial mucosa, so that defect or damage of urothelial cells associated with urinary tract diseases may cause serious problems. If a sufficient number of functional urothelial cells are prepared in culture and trans...

journal_title：Scientific reports

authors： Inoue Y,Kishida T,Kotani SI,Akiyoshi M,Taga H,Seki M,Ukimura O,Mazda O

更新日期：2019-09-25 00:00:00

abstract：:Viral latency remains the most significant obstacle to HIV eradication. Clinical strategies aim to purge the latent CD4+ T cell reservoir by activating viral expression to induce death, but are undercut by the inability to target latently infected cells. Here we explored the acute signaling response of latent HIV-infe...

journal_title：Scientific reports

authors： Fong LE,Sulistijo ES,Miller-Jensen K

更新日期：2017-11-23 00:00:00

abstract：:Phosphorylation plays important roles in several processes including synaptic plasticity and memory. The critical role of extracellular signal-regulated kinase (ERK) in these processes is well established. ERK is activated in a sustained manner by different stimuli. However, the mechanisms of sustained ERK activation ...

journal_title：Scientific reports

authors： Maharana C,Sharma KP,Sharma SK

更新日期：2013-01-01 00:00:00

abstract：:Early diagnosis of dementia including Alzheimer's disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD and amnestic mild ...

journal_title：Scientific reports

authors： Kobayashi N,Shinagawa S,Niimura H,Kida H,Nagata T,Tagai K,Shimada K,Oka N,Shikimoto R,Noda Y,Nakajima S,Mimura M,Shigeta M,Kondo K

更新日期：2020-07-22 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Liu J,Huang W,Ren C,Wen Q,Liu W,Yang X,Wang L,Zhu B,Zeng L,Feng X,Zhang C,Chen H,Jia W,Zhang L,Xia X,Chen Y

更新日期：2020-04-20 00:00:00

abstract：:The cartilaginous and non-neopterygian bony fishes have an electric sense typically comprised of hundreds or thousands of sensory canals distributed in broad clusters over the head. This morphology facilitates neural encoding of local electric field intensity, orientation, and polarity, used for determining the positi...

journal_title：Scientific reports

authors： Berquist RM,Galinsky VL,Kajiura SM,Frank LR

更新日期：2015-03-11 00:00:00

abstract：:Patients who undergo orthotopic liver transplantation often sustain acute kidney injury(AKI). The toll-like receptor 4(TLR4)/Nuclear factor-кB(NF-кB) pathway plays a role in AKI. Dexmedetomidine(Dex) has been shown to attenuate AKI. The current study aimed to determine whether liver transplantation-induced AKI is asso...

journal_title：Scientific reports

authors： Yao H,Chi X,Jin Y,Wang Y,Huang P,Wu S,Xia Z,Cai J

更新日期：2015-11-20 00:00:00

abstract：:The effect of a 2-aminoanthraquinone-graphene oxide (AQ-GO) composite on the anaerobic dechlorination and degradation of chloroanilines by an enriched bacterial consortium was investigated. The results showed that the maximal degradation efficiency of 20 mg/L 2-chloroaniline (2-CA) reached 91.4% at a dose of 20 mg/L A...

journal_title：Scientific reports

authors： Lu H,Zhang T,Zhou Y,Zhou J,Wang J,Wang X

更新日期：2019-08-26 00:00:00

abstract：:Periodontal (gum) disease is a highly prevalent infection and inflammation accounting for the majority of tooth loss in adult population worldwide. Porphyromonas gingivalis is a keystone periodontal pathogen and its lipopolysaccharide (PgLPS) acts as a major virulence attribute to the disease. Herein, we deciphered th...

journal_title：Scientific reports

authors： Herath TDK,Darveau RP,Seneviratne CJ,Wang CY,Wang Y,Jin L

更新日期：2016-08-19 00:00:00

abstract：:The identification of the most influential individuals in structured populations is an important research question, with many applications across the social and natural sciences. Here, we study this problem in evolutionary populations on static networks, where invading cheaters can lead to the collapse of cooperation....

journal_title：Scientific reports

authors： Yang G,Cavaliere M,Zhu C,Perc M

更新日期：2020-02-10 00:00:00

abstract：:Amyloid-β(Aβ) PET positivity in patients with suspected cerebral amyloid angiopathy (CAA) MRI markers is predictive of a worse cognitive trajectory, and it provides insights into the underlying vascular pathology (CAA vs. hypertensive angiopathy) to facilitate prognostic prediction and appropriate treatment decisions....

journal_title：Scientific reports

authors： Jung YH,Lee H,Kim HJ,Na DL,Han HJ,Jang H,Seo SW

更新日期：2020-11-02 00:00:00

abstract：:Surface-enhanced Raman spectroscopy (SERS) has attracted a lot of attention in molecular sensing because of the remarkable ability of plasmonic metal nanostructures to enhance the weak Raman scattering process. On the other hand, coherent vibrational spectroscopy triggered by impulsive excitation using ultrafast laser...

journal_title：Scientific reports

authors： Du J,Harra J,Virkki M,Mäkelä JM,Leng Y,Kauranen M,Kobayashi T

更新日期：2016-11-04 00:00:00

abstract：:Staphylococcus aureus is a medically important pathogen with an abundance of virulence factors that are necessary for survival within a host, including the production of cytolytic toxins. The regulation of toxin production is mediated by the Agr quorum sensing system, and a poorly defined post-exponential growth phase...

journal_title：Scientific reports

authors： Stevens E,Laabei M,Gardner S,Somerville GA,Massey RC

更新日期：2017-10-23 00:00:00

abstract：:Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids (FFA) are essentially unknown, we determined the lipidomic expression profile after burn in correlation to cl...

journal_title：Scientific reports

authors： Qi P,Abdullahi A,Stanojcic M,Patsouris D,Jeschke MG

更新日期：2016-12-16 00:00:00

abstract：:This work presents the measurement of the permittivities of water and methanol in the D-band. Water is a reference medium for dielectric measurement. The dielectric permittivity of water in the millimeter wave range is a fundamental parameter in many applications, and needs to be investigated systematically. The measu...

journal_title：Scientific reports

authors： Liu X,Yu J

更新日期：2019-12-06 00:00:00

abstract：:Steering magnetism by electric fields upon interfacing ferromagnetic (FM) and ferroelectric (FE) materials to achieve an emergent multiferroic response bears a great potential for nano-scale devices with novel functionalities. FM/FE heterostructures allow, for instance, the electrical manipulation of magnetic anisotro...

journal_title：Scientific reports

authors： Jia C,Wang F,Jiang C,Berakdar J,Xue D

更新日期：2015-06-09 00:00:00

abstract：:Miscanthus is a promising lignocellulosic bioenergy crop for bioethanol production. To identify candidate genes and regulation networks involved in secondary cell wall (SCW) development in Miscanthus, we performed de novo transcriptome analysis of a developing internode. According to the histological and in-situ histo...

journal_title：Scientific reports

authors： Hu R,Xu Y,Yu C,He K,Tang Q,Jia C,He G,Wang X,Kong Y,Zhou G

更新日期：2017-08-22 00:00:00

abstract：:Superdirective antennas developed over the last century have received renewed interest in recent years from the development of metamaterials. These arrays of electromagnetic resonators (or meta-atoms) carrying short wavelength electro- and/or magneto-inductive waves support current distributions with very high spatial...

journal_title：Scientific reports

authors： Vallecchi A,Radkovskaya A,Li L,Faulkner G,Stevens CJ,Shamonina E

更新日期：2020-01-14 00:00:00

abstract：:Phylogenetic incongruence has frequently been encountered among different molecular markers. Recent progress in molecular phylogenomics has provided detailed and important information for evolutionary biology and taxonomy. Here we focused on the freshwater viviparid snails (Cipangopaludina chinensis chinensis and C. c...

journal_title：Scientific reports

authors： Hirano T,Saito T,Tsunamoto Y,Koseki J,Ye B,Do VT,Miura O,Suyama Y,Chiba S

更新日期：2019-04-17 00:00:00

abstract：:The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its progression from the preoperative MR radiomics. 57 newly diagnosed cerebral glioblastoma patients were ...

journal_title：Scientific reports

authors： Yan JL,Li C,van der Hoorn A,Boonzaier NR,Matys T,Price SJ

更新日期：2020-06-16 00:00:00

abstract：:Export of messenger ribonucleic acids (mRNAs) into the cytoplasm is a fundamental step in gene regulation processes, which is meticulously quality controlled by highly efficient mechanisms in eukaryotic cells. Yet, it remains unclear how the aberrant mRNAs are recognized and retained inside the nucleus. Using a new mo...

journal_title：Scientific reports

authors： Soheilypour M,Mofrad MR

更新日期：2016-11-02 00:00:00

abstract：:Fasciolosis is common in UK beef cattle, but it is unclear at what levels liver fluke burdens cause production losses. This study aimed to address these uncertainties by estimating the impact of liver fluke infection on UK beef cattle productivity and investigating the use of diagnostic tests in a quantitative manner....

journal_title：Scientific reports

authors： Mazeri S,Rydevik G,Handel I,Bronsvoort BMD,Sargison N

更新日期：2017-08-04 00:00:00

abstract：:Pure iron has been confirmed as a promising biodegradable metal. However, the degradation rate of pure iron should be accelerated to meet the clinical requirements. In this work, two different designs of platinum disc arrays, including sizes of Φ20 μm × S5 μm and Φ4 μm × S4 μm, have been coated on the surface of pure ...

journal_title：Scientific reports

authors： Huang T,Zheng Y

更新日期：2016-04-01 00:00:00

abstract：:Among the bacterial symbionts harbored by the model organism Paramecium, many still lack a recent investigation that includes a molecular characterization. The genus Lyticum consists of two species of large-sized bacteria displaying numerous flagella, despite their inability to move inside their hosts' cytoplasm. We p...

journal_title：Scientific reports

authors： Boscaro V,Schrallhammer M,Benken KA,Krenek S,Szokoli F,Berendonk TU,Schweikert M,Verni F,Sabaneyeva EV,Petroni G

更新日期：2013-11-22 00:00:00

abstract：:Patients with scirrhous gastric cancer (SGC) frequently develop peritoneal dissemination, which leads to poor prognosis. The secreted protein angiopoietin-like-4 (ANGPTL4), which is induced by hypoxia, exerts diverse effects on cancer progression. Here, we aimed to determine the biological function of ANGPTL4 in SGC c...

journal_title：Scientific reports

authors： Baba K,Kitajima Y,Miyake S,Nakamura J,Wakiyama K,Sato H,Okuyama K,Kitagawa H,Tanaka T,Hiraki M,Yanagihara K,Noshiro H

更新日期：2017-09-11 00:00:00

abstract：:Porphyry systems supply most copper and significant gold to our economy. Recent studies indicate that they are frequently associated with high Sr/Y magmatic rocks, but the meaning of this association remains elusive. Understanding the association between high Sr/Y magmatic rocks and porphyry-type deposits is essential...

journal_title：Scientific reports

authors： Chiaradia M,Ulianov A,Kouzmanov K,Beate B

更新日期：2012-01-01 00:00:00