Abstract:
:Elimination of misfolded proteins of the endoplasmic reticulum (ER) requires their retrotranslocation from the ER to the cytosol via membrane-bound ubiquitin ligase complexes. Baldridge and Rapoport now reconstitute a key step of retrotranslocation, demonstrating a protein conduit gated by ubiquitination.
journal_name
Cell Resjournal_title
Cell researchauthors
Zhang T,Ye Ydoi
10.1038/cr.2016.92subject
Has Abstractpub_date
2016-10-01 00:00:00pages
1075-1076issue
10eissn
1001-0602issn
1748-7838pii
cr201692journal_volume
26pub_type
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