Ultrafast Airy beam optical parametric oscillator.

abstract：:Unlike individual, free-floating planktonic bacteria, biofilms are surface-attached communities of slow- or non-replicating bacteria encased within a protective extracellular polymeric matrix enabling persistent bacterial populations to tolerate high concentrations of antimicrobials. Our current antibacterial arsenal ...

journal_title：Scientific reports

authors： Yang H,Abouelhassan Y,Burch GM,Kallifidas D,Huang G,Yousaf H,Jin S,Luesch H,Huigens RW

更新日期：2017-05-17 00:00:00

abstract：:Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomic analysis. We foun...

journal_title：Scientific reports

authors： Kim J,Kim I,Han SK,Bowie JU,Kim S

更新日期：2012-01-01 00:00:00

abstract：:State of charge (SOC) is a crucial index used in the assessment of electric vehicle (EV) battery storage systems. Thus, SOC estimation of lithium-ion batteries has been widely investigated because of their fast charging, long-life cycle, and high energy density characteristics. However, precise SOC assessment of lithi...

journal_title：Scientific reports

authors： Hannan MA,Lipu MSH,Hussain A,Ker PJ,Mahlia TMI,Mansor M,Ayob A,Saad MH,Dong ZY

更新日期：2020-03-13 00:00:00

abstract：:Methylation of DNA CpG sites is a major mechanism of epigenetic gene silencing and plays important roles in cell division, development and carcinogenesis. One of its regulators is the 64-residue C-terminal Transcriptional Repressor Domain (the TRD) of MBD1, which recruits several repressor proteins such as MCAF1, HDAC...

journal_title：Scientific reports

authors： Hameed UF,Lim J,Zhang Q,Wasik MA,Yang D,Swaminathan K

更新日期：2014-05-09 00:00:00

abstract：:Humans walk and run, as well as change their gait speed, through the control of their complicated and redundant musculoskeletal system. These gaits exhibit different locomotor behaviors, such as a double-stance phase in walking and flight phase in running. The complex and redundant nature of the musculoskeletal system...

journal_title：Scientific reports

authors： Aoi S,Ohashi T,Bamba R,Fujiki S,Tamura D,Funato T,Senda K,Ivanenko Y,Tsuchiya K

更新日期：2019-01-23 00:00:00

abstract：:The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary. However, the events and conditions that lead to cancer cell implantati...

journal_title：Scientific reports

authors： Jia D,Nagaoka Y,Katsumata M,Orsulic S

更新日期：2018-08-17 00:00:00

abstract：:Various important topological properties of healthy brain connectome have recently been identified. However, the manner in which brain lesion changes the functional network topology is unknown. We examined how critical specific brain areas are in the maintenance of network topology using multivariate support vector re...

journal_title：Scientific reports

authors： Yuan B,Fang Y,Han Z,Song L,He Y,Bi Y

更新日期：2017-12-20 00:00:00

abstract：:Hirschsprung disease (HSCR) is a common cause of functional colonic obstruction in children. The currently available genetic testing is often inadequate as it mainly focuses on RET and several other genes, accounting for only 15-20% of cases. To identify novel, potentially pathogenic variants, we isolated a panel of g...

journal_title：Scientific reports

authors： Zhang Z,Li Q,Diao M,Liu N,Cheng W,Xiao P,Zou J,Su L,Yu K,Wu J,Li L,Jiang Q

更新日期：2017-11-01 00:00:00

abstract：:Controlling the nanoscale arrangement in polymer-fullerene organic solar cells is of paramount importance to boost the performance of such promising class of photovoltaic diodes. In this work, we use a pseudo-bilayer system made of poly(2,5-bis(3-hexadecylthiophen-2-yl)thieno[3,2-b]thiophene (PBTTT) and [6,6]-phenyl-C...

journal_title：Scientific reports

authors： Paternò GM,Skoda MW,Dalgliesh R,Cacialli F,Sakai VG

更新日期：2016-10-04 00:00:00

abstract：:The AB0 blood group has been linked to ischaemic heart disease, stroke, and periodontal disease, while the Lewis blood group has been linked to ischaemic heart disease and obesity, all of which have been associated with periodontitis. AB0 or Lewis blood group phenotype may therefore constitute common hereditary compon...

journal_title：Scientific reports

authors： Enevold C,Nielsen CH,Molbo D,Lund R,Bendtzen K,Fiehn N-,Holmstrup P

更新日期：2019-04-18 00:00:00

abstract：:Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Herein, we built an ex-...

journal_title：Scientific reports

authors： Li W,Lee S,Ma M,Kim SM,Guye P,Pancoast JR,Anderson DG,Weiss R,Lee RT,Hammond PT

更新日期：2013-10-04 00:00:00

abstract：:We propose a polarization beam splitter (PBS) with a footprint of only 600 × 790 nm2 operating at a wavelength of λ = 1550 nm, which is the smallest PBS ever demonstrated. This device uses CMOS-compatible materials, namely, silicon and silica. The present PBS comprises two Si waveguides with different geometrical aspe...

journal_title：Scientific reports

authors： Lai MS,Huang CC

更新日期：2017-07-03 00:00:00

abstract：:We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacteri...

journal_title：Scientific reports

authors： Cebrián R,Arévalo S,Rubiño S,Arias-Santiago S,Rojo MD,Montalbán-López M,Martínez-Bueno M,Valdivia E,Maqueda M

更新日期：2018-08-06 00:00:00

abstract：:Delivery and expression of recombinant genes, a key methodology for many applications in biological research, remains a challenge especially for mature neurons. Here, we report easy, highly efficient and well tolerated transduction of adult peripheral and central neuronal populations of diverse species in culture usin...

journal_title：Scientific reports

authors： Levin E,Diekmann H,Fischer D

更新日期：2016-12-13 00:00:00

abstract：:Agr family includes three groups of genes, Ag1, Agr2 and Agr3, which encode the thioredoxin domain-containing secreted proteins and have been shown recently to participate in regeneration of the amputated body appendages in amphibians. By contrast, higher vertebrates have only Agr2 and Agr3, but lack Ag1, and have low...

journal_title：Scientific reports

authors： Ivanova AS,Shandarin IN,Ermakova GV,Minin AA,Tereshina MB,Zaraisky AG

更新日期：2015-01-29 00:00:00

abstract：:Conventional myeloablative conditioning (MAC) regimens often cause severe regimen-related toxicity (RRT). Furthermore, many patients suffer from poor quality of life in accordance with the increase in long-term survivors. We therefore devised a reduced-toxicity myeloablative conditioning (RTMAC) regimen consisting of ...

journal_title：Scientific reports

authors： Hirabayashi K,Nakazawa Y,Sakashita K,Kurata T,Saito S,Yoshikawa K,Tanaka M,Yanagisawa R,Koike K

更新日期：2014-11-06 00:00:00

abstract：:Chloroquine (CQ) and hydroxychloroquine, are promising anti-inflammatory drugs for the treatment of Diabetes mellitus (DM) to prevent associated complications. Therefore, this study evaluated the anti-inflammatory effects of CQ-free and CQ-incorporated polylactic acid nanoparticles (NPs) in the peripheral blood mononu...

journal_title：Scientific reports

authors： de Almeida Júnior RF,de Souza KSC,Galdino OA,da Silva Junior AA,Arrais RF,Machado PRL,Farias KJS,de Rezende AA

更新日期：2020-07-21 00:00:00

abstract：:Linear dichroism - the polarization dependent absorption of electromagnetic waves- is routinely exploited in applications as diverse as structure determination of DNA or polarization filters in optical technologies. Here filamentary absorbers with a large length-to-width ratio are a prerequisite. For magnetization dyn...

journal_title：Scientific reports

authors： Stasinopoulos I,Weichselbaumer S,Bauer A,Waizner J,Berger H,Garst M,Pfleiderer C,Grundler D

更新日期：2017-08-01 00:00:00

abstract：:It is challenging to create artificial catalysts that approach enzymes with regard to catalytic efficiency and selectivity. The enantioselective catalysis ranks the privileged characteristic of enzymatic transformations. Here, we report two pyridine-linked bis(β-cyclodextrin) (bisCD) copper(II) complexes that enantios...

journal_title：Scientific reports

authors： Xue SS,Zhao M,Ke ZF,Cheng BC,Su H,Cao Q,Cao ZK,Wang J,Ji LN,Mao ZW

更新日期：2016-02-26 00:00:00

abstract：:The ecosystem of the Source Region of Yangtze River (SRYR) is highly susceptible to climate change. In this study, the spatial-temporal variation of NPP from 2000 to 2014 was analyzed, using outputs of Carnegie-Ames-Stanford Approach model. Then the correlation characteristics of NPP and climatic factors were evaluate...

journal_title：Scientific reports

authors： Yuan Z,Wang Y,Xu J,Wu Z

更新日期：2021-01-14 00:00:00

abstract：:Transfer printing, a two-step process (i.e. picking up and printing) for heterogeneous integration, has been widely exploited for the fabrication of functional electronics system. To ensure a reliable process, strong adhesion for picking up and weak or no adhesion for printing are required. However, it is challenging ...

journal_title：Scientific reports

authors： Sim K,Chen S,Li Y,Kammoun M,Peng Y,Xu M,Gao Y,Song J,Zhang Y,Ardebili H,Yu C

更新日期：2015-11-10 00:00:00

abstract：:Gentamicin may cause acute kidney injury. The pathogenesis of gentamicin nephrotoxicity is unclear. Autophagy is a highly conserved physiological process involved in removing damaged or aged biological macromolecules and organelles from the cytoplasm. The role of autophagy in the pathogenesis of gentamicin nephrotoxic...

journal_title：Scientific reports

authors： Cui J,Bai XY,Sun X,Cai G,Hong Q,Ding R,Chen X

更新日期：2015-06-08 00:00:00

abstract：:There is strong in vitro cell survival evidence that the relative biological effectiveness (RBE) of protons is variable, with dependence on factors such as linear energy transfer (LET) and dose. This is coupled with the growing in vivo evidence, from post-treatment image change analysis, of a variable RBE. Despite thi...

journal_title：Scientific reports

authors： Smith EAK,Henthorn NT,Warmenhoven JW,Ingram SP,Aitkenhead AH,Richardson JC,Sitch P,Chadwick AL,Underwood TSA,Merchant MJ,Burnet NG,Kirkby NF,Kirkby KJ,Mackay RI

更新日期：2019-12-27 00:00:00

abstract：:CRISPR-Cas9 is a powerful new tool for genome editing, but this technique creates mosaic mutations that affect the efficiency and precision of its ability to edit the genome. Reducing mosaic mutations is particularly important for gene therapy and precision genome editing. Although the mechanisms underlying the CRSIPR...

journal_title：Scientific reports

authors： Tu Z,Yang W,Yan S,Yin A,Gao J,Liu X,Zheng Y,Zheng J,Li Z,Yang S,Li S,Guo X,Li XJ

更新日期：2017-02-03 00:00:00

abstract：:Ammonia can be utilised as an alternative nitrogen source to glutamine to support cell proliferation. However, the underlying molecular mechanisms and whether all cells have this ability is not fully understood. We find that eleven cancer and non-cancerous cell lines have opposite abilities to tolerate and utilise amm...

journal_title：Scientific reports

authors： Lie S,Wang T,Forbes B,Proud CG,Petersen J

更新日期：2019-02-06 00:00:00

abstract：:Despite numerous advances in genomics and bioinformatics, technological hurdles remain to examine host-microbe transcriptomics. Sometimes the transcriptome of either or both can be ascertained merely by generating more sequencing reads. However, many cases exist where bacterial mRNA needs to be enriched further to ena...

journal_title：Scientific reports

authors： Kumar N,Lin M,Zhao X,Ott S,Santana-Cruz I,Daugherty S,Rikihisa Y,Sadzewicz L,Tallon LJ,Fraser CM,Dunning Hotopp JC

更新日期：2016-10-07 00:00:00

abstract：:Hybridization between heterospecific individuals has been documented as playing a direct role in promoting paternal leakage and mitochondrial heteroplasmy in both natural populations and laboratory conditions, by relaxing the egg-sperm recognition mechanisms. Here, we tested the hypothesis that hybridization can lead ...

journal_title：Scientific reports

authors： Mastrantonio V,Urbanelli S,Porretta D

更新日期：2019-12-16 00:00:00

abstract：:Micronutrient deficiency is common in patients with HIV/AIDS, usually caused by mal-absorption and/or drug interactions. 25-hydroxyvitamin D is of fundamental importance for the homeostasis of musculoskeletal health. The current study aimed to evaluate the nutritional status of HIV-infected subjects in order to make t...

journal_title：Scientific reports

authors： Sales SH,Matta SM,da Silva DC,Assone TA,Fonseca LA,Duarte AJ,Casseb J

更新日期：2015-08-10 00:00:00

abstract：:MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syn...

journal_title：Scientific reports

authors： López-Mejías R,Remuzgo-Martínez S,Genre F,Pulito-Cueto V,Rozas SMF,Llorca J,Fernández DI,Cuesta VMM,Ortego-Centeno N,Gómez NP,Mera-Varela A,Martínez-Barrio J,López-Longo FJ,Mijares V,Lera-Gómez L,Usetti MP,Laporta R,Pér

更新日期：2020-01-29 00:00:00

abstract：:There were significant differences in response and pharmacokinetic characteristics to the peginterferon α2a treatment among Chronic Hepatitis B (CHB) patients. The aim of this study is to identify factors which could significantly impact the peginterferon α2a pharmacokinetic characteristics in CHB patients. There were...

journal_title：Scientific reports

authors： Bi J,Li X,Liu J,Chen D,Li S,Hou J,Zhou Y,Zhu S,Zhao Z,Qin E,Wei Z

更新日期：2017-08-11 00:00:00