Abstract：
:We propose a polarization beam splitter (PBS) with a footprint of only 600 × 790 nm2 operating at a wavelength of λ = 1550 nm, which is the smallest PBS ever demonstrated. This device uses CMOS-compatible materials, namely, silicon and silica. The present PBS comprises two Si waveguides with different geometrical aspect ratios adjoined side-by-side, which separates the transverse-electric (TE) and transverse-magnetic (TM) modes without relying on an additional coupling region. The designed PBS achieves a polarization extinction ratio of approximately 25 dB for both modes and insertion losses of approximately 0.87 and 1.09 dB for the TE and TM polarizations, respectively. Over a wide bandwidth of 150 nm (from λ = 1475-1625 nm), a high polarization extinction ratio (greater than 20 dB) and a low inversion loss (lower than 1.3 dB) can be obtained. The proposed PBS allows for geometrical errors of ±15 nm while maintaining a polarization extinction ratio of >20 dB and inversion losses of >1.1 and 1.3 dB for the TE and TM modes, respectively. With the submicron footprint, the reported PBS may be able to be used in high-density photonic integrated circuits and nanophotonic devices.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lai MS,Huang CCdoi
10.1038/s41598-017-05019-3subject
Has Abstractpub_date
2017-07-03 00:00:00pages
4531issue
1issn
2045-2322pii
10.1038/s41598-017-05019-3journal_volume
7pub_type
杂志文章abstract：:An understanding of load sharing among constituent phases aids in designing mechanical properties of multiphase materials. Here we investigate load partitioning between the body-centered-cubic iron matrix and NiAl-type precipitates in a ferritic alloy during uniaxial tensile tests at 364 and 506 °C on multiple length ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23137
更新日期：2016-03-16 00:00:00
abstract：:During skin healing, periostin facilitates myofibroblast differentiation through a β1 integrin/FAK dependent mechanism and continued expression is associated with scarring. In contrast to skin, gingival tissue does not typically scar upon injury, but the role of periostin in gingival healing has never been investigate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35805-6
更新日期：2019-02-25 00:00:00
abstract：:Fibroblast growth factor 21 (FGF21) and cytokeratin 18 (CK18) were previously reported to be elevated in nonalcoholic fatty liver disease (NAFLD). We aim to analyze the differential roles of FGF21, cell apoptosis marker CK18 fragment M30 and total cell death marker CK18 M65ED in monitoring the different stages of NAFL...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05257-5
更新日期：2017-07-11 00:00:00
abstract：:The impact of obesity on health-related quality of life (HRQoL) in chronic kidney disease (CKD) population has not been elucidated, despite the impairment of HRQoL in the obese among general population. We hypothesized that the impact of obesity on HRQoL might be confounded by impaired renal function in CKD population...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59382-9
更新日期：2020-02-11 00:00:00
abstract：:Arctic amplification of global warming has led to increased summer sea ice retreat, which influences gas exchange between the Arctic Ocean and the atmosphere where sea ice previously acted as a physical barrier. Indeed, recently observed enhanced atmospheric methane concentrations in Arctic regions with fractional sea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16179
更新日期：2015-11-10 00:00:00
abstract：:We sought to analyse plasma levels of peripheral blood microRNAs (miRs) as biomarkers of ST-segment-elevation myocardial infarction (STEMI) due to type-1 myocardial infarction as a model situation of vulnerable plaque (VP) rupture. Samples of 20 patients with STEMI were compared both with a group of patients without a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62835-w
更新日期：2020-04-03 00:00:00
abstract：:We perform a detailed theoretical and experimental investigation of supercontinuum generation in large-mode-area photonic crystal fibers pumped by a high-energy, high-repetition rate picosecond Nd:YVO4 laser, with the goal of using it as the Stokes beam in coherent anti-Stokes Raman scattering setup. We analyze the in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27811-5
更新日期：2018-06-22 00:00:00
abstract：:As the natural boundary between the Yunnan-Guizhou Plateau and the Hengduan Mountains in China, the large-scale prominent terrain of Ailaoshan Mountain leads to obvious regional differences in climate and vegetation. In this article, a comparative analysis is made on both species composition and floristic components o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48324-9
更新日期：2019-08-19 00:00:00
abstract：:New small molecules that regulate the step-wise differentiation of human pluripotent stem cells into dopaminergic neurons have been identified. The steroid, guggulsterone, was found to be the most effective inducer of neural stem cells into dopaminergic neurons. These neurons are extensively characterized and shown to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01463
更新日期：2013-01-01 00:00:00
abstract：:The plasmodial CTP:phosphocholine cytidylyltransferase (PfCCT) is a promising antimalarial target, which can be inhibited to exploit the need for increased lipid biosynthesis during the erythrocytic life stage of Plasmodium falciparum. Notable structural and regulatory differences of plasmodial and mammalian CCTs offe...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27183-w
更新日期：2018-06-12 00:00:00
abstract：:For a number of years nanomaterials have been continuously devised and comprehensively investigated because of the growing demand for them and their multifarious applications, especially in medicine. This paper reports on the properties of SrF2 nanoparticles (NPs) for applications in biomedicine, showing effective way...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45025-1
更新日期：2019-06-17 00:00:00
abstract：:Silver nanowires (AgNWs) networks are promising candidates for the replacement of indium tin oxide (ITO). However, the surface roughness of the AgNWs network is still too high for its application in optoelectronic devices. In this work, we have reduced the surface roughness of the AgNWs networks to 6.4 nm, compared to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45392
更新日期：2017-03-28 00:00:00
abstract：:We investigated whether clinical factors including comorbidities, medications, and laboratory results predict inpatient fall risk in older adults. The participants in this case-control study included hospitalized older adults with acute conditions who had falls during their hospital stay (case group) and 410 hospitali...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81034-9
更新日期：2021-01-15 00:00:00
abstract：:The Lesotho guidelines for the management of drug-resistant tuberculosis (TB) recommend initiation of patients diagnosed with rifampicin resistant (RR)-TB on a standardized drug resistant regimen while awaiting confirmation of rifampicin resistant TB (RR-TB) and complete drug susceptibility test results. Review of dia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58690-4
更新日期：2020-02-05 00:00:00
abstract：:Silk suture material is primarily composed of silk fibroin and regarded as a non-resorbable material. It is slowly degraded by proteolysis when it is implanted into the body. 4-Hexylresorcinol (4HR) is a well-known antiseptic. In this study, the biodegradability of 4HR-incorporated silk sutures were compared to that o...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42441
更新日期：2017-02-13 00:00:00
abstract：:The effective differentiation between multiple primary lung tumors (MPs) and intrapulmonary metastases (IMs) in patients is imperative to discover the exact disease stage and to select the most appropriate treatment. In this study, the authors was to evaluate the efficacy and validity of large-scale targeted sequencin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75935-4
更新日期：2020-11-02 00:00:00
abstract：:Single molecule microarrays have been used in quantitative proteomics, in particular, single cell analysis requiring high sensitivity and ultra-low limits of detection. In this paper, several image analysis methods are evaluated for their ability to accurately enumerate single molecules bound to a microarray spot. Cru...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18303-z
更新日期：2017-12-20 00:00:00
abstract：:Silver nanoparticles (AgNPs) have been extensively used and are considered as an emerging contaminant in the ocean. The environmental contamination of AgNPs is expected to increase greatly over time, and cetaceans, as the top ocean predators, will suffer the negative impacts of AgNPs. In the present study, we investig...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23737-0
更新日期：2018-04-04 00:00:00
abstract：:Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60198-w
更新日期：2020-02-26 00:00:00
abstract：:We developed a new concept of X- and γ-ray radiation semiconductor detectors based on a large area graphene/semi-insulating single crystal CdTe Schottky-type heterojunction. These two terminal electronic devices can be easily fabricated by forming a Van der Waals contact between large area chemical vapor deposited gra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37637-w
更新日期：2019-01-31 00:00:00
abstract：:An important step in oxide photochemistry, the loading of electrons into shallow trap states, was studied using infrared (IR) spectroscopy on both, rutile TiO2 powders and single-crystal, r-TiO2(110) oriented samples. After UV-irradiation or n-doping by exposure to H-atoms broad IR absorption lines are observed for th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03808
更新日期：2014-01-22 00:00:00
abstract：:There is no preclinical mouse model to investigate pulmonary Mycobacteroides abscessus (formerly Mycobacterium abscessus) infection in an immunocompetent mouse strain, especially in the context of antibiotic testing and regimen development. We developed a mouse model of pulmonary M. abscessus infection using the aeros...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60452-1
更新日期：2020-02-28 00:00:00
abstract：:A hypereutectic Al-Fe-Cu alloy with a high-volume fraction ferro-aluminum second phase (AlFe phases for short) was reheated in the solid-liquid region and the microstructure evolution was investigated. During semisolid heating, the high-melting AlFe phases in the Al-Fe-Cu alloy were demonstrated to stunt the grain gro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-80983-5
更新日期：2021-01-15 00:00:00
abstract：:Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid response elements (G...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25393-w
更新日期：2018-05-10 00:00:00
abstract：:Bacterial cell wall is targeted by many antibiotics. Among them are lantibiotics, which realize their function via interaction with plasma membrane lipid-II molecule - a chemically conserved part of the cell wall synthesis pathway. To investigate structural and dynamic properties of this molecule, we have performed a ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01678
更新日期：2013-01-01 00:00:00
abstract：:No consensus currently exist on the optimal treatment of patients with high-risk nonmuscle invasive (HGT1) micropapillary variant of bladder cancer (MPBC). Transcripsome analysis may allow stratification of MPBC-HGT1 enabling prediction of recurrence and guide therapeutic management for individual patients. Whole tran...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76904-7
更新日期：2020-11-18 00:00:00
abstract：:Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regeneration. Interestingly, the transmembrane form of tumor necrosis factor (tmTNF) is necessary to robustly activate TNFR2. To characterize the stoichiometry and composition of tmTNF during TNFR2 activation, we constructed dif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06993-4
更新日期：2017-07-26 00:00:00
abstract：:Cerebrospinal fluid (CSF) biomarkers are useful in the diagnosis and the prediction of progression of several neurodegenerative diseases. Among them, CSF neurofilament light (NfL) protein has particular interest, as its levels reflect neuroaxonal degeneration, a common feature in various neurodegenerative diseases. In...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66090-x
更新日期：2020-06-08 00:00:00
abstract：:Multiphoton excitation microscopy (MPM) is regarded as an effective tool that enables the visualization of deep regions within living tissues and organs, with little damage. Here, we report novel non-labeling MPM (NL-MPM) imaging of fresh human colorectal mucosa, which is useful for discriminating cancer lesions from ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07244-2
更新日期：2017-07-31 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-62007-w
更新日期：2020-03-18 00:00:00
