Ancient hybridization and mtDNA introgression behind current paternal leakage and heteroplasmy in hybrid zones.

abstract：:The extended Hückel (eH) tight-binding method has historically been prized for its computational ease and intuitive chemical clarity. However, its lack of quantitative predictiveness has prevented the eH method from being used as a tool for rapidly screening materials for desired electronic properties. In this work, w...

journal_title：Scientific reports

authors： Grabill LP,Berger RF

更新日期：2018-07-12 00:00:00

abstract：:Long interspersed element-1 (LINE-1, L1) is a mobile genetic element comprising about 17% of the human genome. L1 utilizes an endonuclease to insert L1 cDNA into the target genomic DNA, which induces double-strand DNA breaks in the human genome and activates the DNA damage signaling pathway, resulting in the recruitme...

journal_title：Scientific reports

authors： Ariumi Y,Kawano K,Yasuda-Inoue M,Kuroki M,Fukuda H,Siddiqui R,Turelli P,Tateishi S

更新日期：2018-10-26 00:00:00

abstract：:The electrohydrodynamic (EHD) jet spraying process is a good method for making quantum dot (QD) layers in light-emitting diodes (LEDs). However, controlling the morphology and large-scale fabrication of the QD layers are critical for realizing all-solution-processed QD-LEDs with high performance. Three spraying techni...

journal_title：Scientific reports

authors： Nguyen TC,Can TTT,Choi WS

更新日期：2019-09-25 00:00:00

abstract：:Surface enhanced Raman scattering (SERS) spectroscopy becomes increasingly used in biosensors for its capacity to detect and identify single molecules. In practice, a large number of SERS spectra are acquired and reliable ranking methods are thus essential for analysing all these data. Supervised classification strate...

journal_title：Scientific reports

authors： Leray A,Brulé T,Buret M,Colas des Francs G,Bouhelier A,Dereux A,Finot E

更新日期：2016-02-02 00:00:00

abstract：:The study utilizes autofluorescence spectroscopy (AFS) along with multivariate spectral analysis for differentiating various stages of hepatic fibrosis. AFS has recently emerged as an efficient tool for evaluating the variations in different endogenous flurophores. In this study, the potential of AFS for differentiati...

journal_title：Scientific reports

authors： Nazeer SS,Saraswathy A,Shenoy SJ,Jayasree RS

更新日期：2018-07-20 00:00:00

abstract：:To determine the incidence of acute cardiac injury (ACI), the factors associated with ACI and the in-hospital mortality in patients with COVID-19, especially in severe patients. All consecutive in-patients with laboratory-confirmed COVID-19 from Tongji Hospital in Wuhan during February 1 and March 29, 2020 were includ...

journal_title：Scientific reports

authors： He X,Wang L,Wang H,Xie Y,Yu Y,Sun J,Yan J,Du Y,Shen Y,Zeng H

更新日期：2020-11-24 00:00:00

abstract：:Gapmer antisense oligonucleotides cleave target RNA effectively in vivo, and is considered as promising therapeutics. Especially, gapmers modified with locked nucleic acid (LNA) shows potent knockdown activity; however, they also cause hepatotoxic side effects. For developing safe and effective gapmer drugs, a deeper ...

journal_title：Scientific reports

authors： Kasuya T,Hori S,Watanabe A,Nakajima M,Gahara Y,Rokushima M,Yanagimoto T,Kugimiya A

更新日期：2016-07-27 00:00:00

abstract：:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. ...

journal_title：Scientific reports

authors： Isaacs AT,Lynd A,Donnelly MJ

更新日期：2017-04-25 00:00:00

abstract：:To improve estimates of the long-term response of the marine carbon system to climate change a better understanding of the seasonal and interannual variability is needed. We use high-frequency multi-year data at three locations identified as climate change hotspots: two sites located close to South Pacific boundary cu...

journal_title：Scientific reports

authors： C Pardo P,Tilbrook B,van Ooijen E,Passmore A,Neill C,Jansen P,Sutton AJ,Trull TW

更新日期：2019-05-20 00:00:00

abstract：:Acquisition of nutrients during intra-vacuolar growth of L. pneumophila within macrophages or amoebae is poorly understood. Since many genes of L. pneumophila are acquired by inter-kingdom horizontal gene transfer from eukaryotic hosts, we examined the presence of human solute carrier (SLC)-like transporters in the L....

journal_title：Scientific reports

authors： Best A,Jones S,Abu Kwaik Y

更新日期：2018-05-29 00:00:00

abstract：:The interaction between roots and bacterial communities in halophytic species is poorly understood. Here, we used Jerusalem artichoke cultivar Nanyu 1 (NY-1) to characterise root distribution patterns and determine diversity and abundance of bacteria in the rhizosphere soil under variable salinity. Root growth was not...

journal_title：Scientific reports

authors： Yang H,Hu J,Long X,Liu Z,Rengel Z

更新日期：2016-02-08 00:00:00

abstract：:Contact investigation is an important and effective active case-finding strategy, but there is a lack of research on congregate settings in countries with an intermediate incidence. This study determined the incidence of and risk factors for tuberculosis (TB) development after exposure in congregate settings. This ret...

journal_title：Scientific reports

authors： Park SY,Han S,Kim YM,Kim J,Lee S,Yang J,Kim UN,Park MS

更新日期：2020-01-28 00:00:00

abstract：:Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is used as a first-line treatment for advanced non-small cell lung cancer (NSCLC). However, most NSCLC patients inevitably develop gefitinib resistance, and the mechanisms underlying this resistance are not fully understood. In this study...

journal_title：Scientific reports

authors： Cao X,Lai S,Hu F,Li G,Wang G,Luo X,Fu X,Hu J

更新日期：2017-06-07 00:00:00

abstract：:In our previous study, a liver-targeting peptide CSP I-plus modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed and showed potent antiangiogenic capability and could specifically bind to human hepatocellular carcinoma cells to make a direct inhibition in vitro. In this study, the bi...

journal_title：Scientific reports

authors： Yan M,Dongmei B,Jingjing Z,Xiaobao J,Jie W,Yan W,Jiayong Z

更新日期：2017-10-26 00:00:00

abstract：:The interaction between two different materials can present novel phenomena that are quite different from the physical properties observed when each material stands alone. Strong electronic correlations, such as magnetism and superconductivity, can be produced as the result of enhanced Coulomb interactions between ele...

journal_title：Scientific reports

authors： Hwang C,Cybart SA,Shin SJ,Kim S,Kim K,Rappoport TG,Wu SM,Jozwiak C,Fedorov AV,Mo SK,Lee DH,Min BI,Haller EE,Dynes RC,Castro Neto AH,Lanzara A

更新日期：2016-02-18 00:00:00

abstract：:In this work, we demonstrate an innovative approach, combing a novel active screen plasma (ASP) technique with green chemical synthesis, for a direct fabrication of uniform Pt nanowire arrays on large-area supports. The ASP treatment enables in-situ N-doping and surface modification to the support surface, significant...

journal_title：Scientific reports

authors： Du S,Lin K,Malladi SK,Lu Y,Sun S,Xu Q,Steinberger-Wilckens R,Dong H

更新日期：2014-09-22 00:00:00

abstract：:We evaluated surgical outcomes of bilateral rectus (BLR) recession in patients with intermittent exotropia who underwent diagnostic monocular occlusion. Records of patients with intermittent exotropia who were preoperatively examined one-hour monocular occlusion and underwent BLR recession were reviewed retrospectivel...

journal_title：Scientific reports

authors： Lee JY,Song JE,Chang HR,Choi CY,Han SY

更新日期：2020-05-08 00:00:00

abstract：:The epidermis of snakes efficiently protects against dehydration and mechanical stress. However, only few proteins of the epidermal barrier to the environment have so far been identified in snakes. Here, we determined the organization of the Epidermal Differentiation Complex (EDC), a cluster of genes encoding protein ...

journal_title：Scientific reports

authors： Holthaus KB,Mlitz V,Strasser B,Tschachler E,Alibardi L,Eckhart L

更新日期：2017-03-27 00:00:00

abstract：:IgE, forming an immune complex with small proteins, can enhance the specific antibody and CD4(+) T cell responses in vivo. The effects require the presence of CD23 (Fcε-receptor II)(+) B cells, which capture IgE-complexed antigens (Ag) in the circulation and transport them to splenic B cell follicles. In addition, als...

journal_title：Scientific reports

authors： Ding Z,Dahlin JS,Xu H,Heyman B

更新日期：2016-06-16 00:00:00

abstract：:Lung cancer is one of the leading causes of cancer-related deaths. It is diagnosed mostly at the locally advanced or metastatic stage. Recently, micro RNAs (miRs) and their distribution in circulation have been implicated in physiological and pathological processes. In this study, miR-126 was evaluated in serum, exoso...

journal_title：Scientific reports

authors： Grimolizzi F,Monaco F,Leoni F,Bracci M,Staffolani S,Bersaglieri C,Gaetani S,Valentino M,Amati M,Rubini C,Saccucci F,Neuzil J,Tomasetti M,Santarelli L

更新日期：2017-11-10 00:00:00

abstract：:Exosomes contain cell-specific collections of bioactive materials including proteins, lipids, and RNAs that are transported to recipient cells to exert their impacts. MicroRNAs (miRNAs) can function as tumor suppressor or oncogenic genes and miR-21 is one of the most frequently up-regulated miRNAs in solid tumors incl...

journal_title：Scientific reports

authors： Sun LH,Tian D,Yang ZC,Li JL

更新日期：2020-05-19 00:00:00

abstract：:The caseinolytic protease machinery associated chaperone protein ClpC is known to be present in bacteria, plants and other eukaryotes, whereas ClpD is unique to plants. Plant ClpC and ClpD proteins get localized into chloroplast stroma. Herein, we report high resolution crystal structures of the N-terminal domain of A...

journal_title：Scientific reports

authors： Mohapatra C,Kumar Jagdev M,Vasudevan D

更新日期：2017-03-13 00:00:00

abstract：:CD4+Foxp3+ regulatory T cells (Tregs) are the main immune suppressors with subpopulation of inflamed-tissue related memory Tregs (mTregs) and non-related resting Treg (rTregs). Previously, Treg was proposed to be the cause of chronicity of hepatitis B virus (HBV) infection but with controversies. We then investigated ...

journal_title：Scientific reports

authors： Hu CC,Jeng WJ,Chen YC,Fang JH,Huang CH,Teng W,Hsieh YC,Lin YC,Chien RN,Sheen IS,Lin CY

更新日期：2017-11-10 00:00:00

abstract：:Northern and tropical peatlands represent a globally significant carbon reserve accumulated over thousands of years of waterlogged conditions. It is unclear whether moderate drying predicted for northern peatlands will stimulate burning and carbon losses as has occurred in their smaller tropical counterparts where the...

journal_title：Scientific reports

authors： Kettridge N,Turetsky MR,Sherwood JH,Thompson DK,Miller CA,Benscoter BW,Flannigan MD,Wotton BM,Waddington JM

更新日期：2015-01-27 00:00:00

abstract：:In the phytopathogenic basidiomycete Ustilago maydis, the Num1 protein has a pivotal function in hyphal morphogenesis. Num1 functions as a core component of the spliceosome-associated Prp19/CDC5 complex (NTC). The interaction of Num1 with the kinesin motor Kin1 suggests a connection between a component of the splicing...

journal_title：Scientific reports

authors： Zhou L,Obhof T,Schneider K,Feldbrügge M,Nienhaus GU,Kämper J

更新日期：2018-02-26 00:00:00

abstract：:The intrinsic functional architecture of the brain supports moment-to-moment maintenance of an internal model of the world. We hypothesized and found three interdependent architectural gradients underlying the organization of intrinsic functional connectivity within the human cerebral cortex. We used resting state fMR...

journal_title：Scientific reports

authors： Zhang J,Abiose O,Katsumi Y,Touroutoglou A,Dickerson BC,Barrett LF

更新日期：2019-11-04 00:00:00

abstract：:Bacterial infection and sepsis are common complications of chronic kidney disease (CKD). A vicious cycle of increased gut permeability, endotoxemia, inadequate activation of the innate immune system and resulting innate immune dysfunction is hypothesized. We assessed endotoxemia, neutrophil function and its relation t...

journal_title：Scientific reports

authors： Lemesch S,Ribitsch W,Schilcher G,Spindelböck W,Hafner-Gießauf H,Marsche G,Pasterk L,Payerl D,Schmerböck B,Tawdrous M,Rosenkranz AR,Stiegler P,Kager G,Hallström S,Oettl K,Eberhard K,Horvath A,Leber B,Stadlbauer V

更新日期：2016-10-04 00:00:00

abstract：:Protein ubiquitination, which is a major post-translational modifications that occurs in eukaryotic cells, is involved in diverse biological processes. To date, large-scale profiling of the ubiquitome in common wheat has not been reported, despite its status as the major cereal crop in the world. Here, we performed th...

journal_title：Scientific reports

authors： Zhang N,Zhang L,Shi C,Tian Q,Lv G,Wang Y,Cui D,Chen F

更新日期：2017-10-19 00:00:00

abstract：:The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This has important implic...

journal_title：Scientific reports

authors： Zhang H,Lim HS,Knapp B,Deane CM,Aleksic M,Dushek O,van der Merwe PA

更新日期：2016-10-13 00:00:00

abstract：:Endothelin-1 (ET-1) is associated with endothelial dysfunction and vasoconstriction. Increased circulating ET-1 levels are associated with long-term cardiovascular mortality. Renalase, released from kidney, metabolizes catecholamines and regulates blood pressure. An increase in circulating renalase levels has been rep...

journal_title：Scientific reports

authors： Li YH,Sheu WH,Lee WJ,Wang J-,Fu CP,Liang KW,Lee IT

更新日期：2018-05-09 00:00:00