Influence of surface modulations by enzymes and monoclonal antibodies on alternative complement pathway activation by Yersinia enterocolitica.

abstract：:Fibronectin binds to Streptococcus pyogenes, and this binding is inhibited by lipoteichoic acid (LTA). Previous studies have shown that LTA can be released from S. pyogenes by treatment with penicillin. Penicillin released LTA from both S. pyogenes and Staphylococcus aureus; however, the binding of fibronectin correla...

journal_title：Infection and immunity

authors： Nealon TJ,Beachey EH,Courtney HS,Simpson WA

更新日期：1986-02-01 00:00:00

abstract：:NF-κB is a critical regulator of gene expression during severe infections. NF-κB comprises homo- and heterodimers of proteins from the Rel family. Among them, p50 and p65 have been clearly implicated in the pathophysiology of sepsis. In contrast, the role of cRel in sepsis is still controversial and has been poorly st...

journal_title：Infection and immunity

authors： Courtine E,Pène F,Cagnard N,Toubiana J,Fitting C,Brocheton J,Rousseau C,Gerondakis S,Chiche JD,Ouaaz F,Mira JP

更新日期：2011-05-01 00:00:00

abstract：:Knowledge of whether Mycobacterium tuberculosis resides within a relatively impermeable membrane-bound vacuole or is free within the cytoplasm within its host cell is central to an understanding of the immunobiology of this intracellular parasite but is a matter of controversy. To explore this issue, we assessed the a...

journal_title：Infection and immunity

authors： Clemens DL,Lee BY,Horwitz MA

更新日期：2002-10-01 00:00:00

abstract：:We produced anti-idiotype antibodies to antibody to lipid A from Eikenella corrodens. The ALA-1 monoclonal antibody (immunoglobulin M [IgM] isotype), which had already been produced in our laboratory (T. Kato, I. Takazoe, and K. Okuda, Infect. Immun. 57:656-659, 1989), had reacted strongly with lipid A from E. corrode...

journal_title：Infection and immunity

authors： Kato T,Takazoe I,Okuda K

更新日期：1990-02-01 00:00:00

abstract：:Immunity to pneumococcal colonization in mice by exposure to live or killed pneumococci has been shown to be antibody independent but dependent on CD4+ T cells. Here we show that intranasal immunization with pneumococcal proteins (pneumococcal surface protein C, adhesin A, and a pneumolysoid) can elicit a similar mech...

journal_title：Infection and immunity

authors： Basset A,Thompson CM,Hollingshead SK,Briles DE,Ades EW,Lipsitch M,Malley R

更新日期：2007-11-01 00:00:00

abstract：:The hydrolysis of urea by ureases of oral bacteria in dental plaque can cause a considerable increase in plaque pH, which can inhibit the development of dental caries. There is also indirect evidence that urea metabolism may promote the formation of calculus and that ammonia release from urea could exacerbate periodon...

journal_title：Infection and immunity

authors： Morou-Bermudez E,Burne RA

更新日期：2000-12-01 00:00:00

abstract：:Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4(+)-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4(+)-T-cell response in vivo and yielding in vitro stimulation of specific CD4(+) T cells at a 100-times-higher molar efficie...

journal_title：Infection and immunity

authors： Loucká J,Schlecht G,Vodolánová J,Leclerc C,Sebo P

更新日期：2002-02-01 00:00:00

abstract：:Antimicrobial factors were analyzed in samples of whole saliva from 31 children, aged 0.8 to 3.8 years. When compared with the adult reference group, the children displayed similar levels of lysozyme, salivary peroxidase, and hypothiocyanite (OSCN-), whereas the amounts of immunoglobulins (isotypes A, G, and M), lacto...

journal_title：Infection and immunity

authors： Tenovuo J,Lehtonen OP,Aaltonen AS,Vilja P,Tuohimaa P

更新日期：1986-01-01 00:00:00

abstract：:Lipopolysaccharide (LPS) has recently been shown to facilitate macrophage foam cell formation and has been suggested to be a proatherogenic factor. The mechanism of LPS induced cholesterol accumulation, however, is unclear. In this report, using the macrophage-like RAW 264.7 cell line, we provide experimental evidence...

journal_title：Infection and immunity

authors： Baranova I,Vishnyakova T,Bocharov A,Chen Z,Remaley AT,Stonik J,Eggerman TL,Patterson AP

更新日期：2002-06-01 00:00:00

abstract：:Leptospira interrogans is an important mammalian pathogen. Transmission from an environmental source requires adaptations to a range of new environmental conditions in the organs and tissues of the infected host. Since many pathogenic bacteria utilize temperature to discern their environment and regulate the synthesis...

journal_title：Infection and immunity

authors： Nally JE,Timoney JF,Stevenson B

更新日期：2001-01-01 00:00:00

abstract：:A hallmark of Bartonella henselae is persistent bacteremia in cats despite the presence of a vigorous host immune response. To understand better the long-term survival of B. henselae in cats, we examined the feline humoral immune response to B. henselae outer membrane (OM) proteins in naturally and experimentally infe...

journal_title：Infection and immunity

authors： Chenoweth MR,Greene CE,Krause DC,Gherardini FC

更新日期：2004-06-01 00:00:00

abstract：:Changes in cell viability and in factors affecting metabolic integrity were examined after exposure of Escherichia coli LP1092 to human serum. Antibody-dependent classical pathway activity accounted for the rapid killing of strain LP1092 by complement. Removal of serum lysozyme by bentonite absorption or by neutraliza...

journal_title：Infection and immunity

authors： Taylor PW,Kroll HP

更新日期：1983-01-01 00:00:00

abstract：:Ers has been qualified as the PrfA-like transcriptional regulator of Enterococcus faecalis. In a previous study we reported that Ers is important for the survival within macrophages of this opportunist pathogenic bacterium. In the present work we have used proteomic and microarray expression profiling of E. faecalis J...

journal_title：Infection and immunity

authors： Riboulet-Bisson E,Sanguinetti M,Budin-Verneuil A,Auffray Y,Hartke A,Giard JC

更新日期：2008-07-01 00:00:00

abstract：:The antigenic relationship of glucosyltransferases (GTF) produced by different serotypes of Streptococcus mutans was studied by using a functional inhibition assay. Rat, rabbit, or hamster immune fluids, directed to cell-associated or supernatant-derived GTF, were tested against ammonium sulfate-precipitated culture s...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA

更新日期：1977-01-01 00:00:00

abstract：:The role of the hypothalamus-pituitary-adrenal (HPA) axis in regulating the growth of Mycobacterium avium in Mycobacterium bovis BCG-resistant and -susceptible congenic mice was evaluated. Restraint was used to activate the HPA axis, which resulted in an increase in the level of corticosterone in the plasma. Activatio...

journal_title：Infection and immunity

authors： Brown DH,Sheridan J,Pearl D,Zwilling BS

更新日期：1993-11-01 00:00:00

abstract：:Salmonellae with differences only in the O-antigenic polysaccharide of their lipopolysaccharide were previously shown to differentially activate complement via the alternative pathway, causing them to be ingested at different rates by the mouse macrophage-like cell line J774. We now show that this mechanism could expl...

journal_title：Infection and immunity

authors： Liang-Takasaki CJ,Saxén H,Mäkelä PH,Leive L

更新日期：1983-08-01 00:00:00

abstract：:Borrelia burgdorferi is a causative agent of Lyme disease, the most common arthropod-borne disease in the United States. B. burgdorferi evades host immune defenses to establish a persistent, disseminated infection. Previous work showed that P66-deficient B. burgdorferi (Δp66) is cleared quickly after inoculation in mi...

journal_title：Infection and immunity

authors： Curtis MW,Hahn BL,Zhang K,Li C,Robinson RT,Coburn J

更新日期：2018-01-22 00:00:00

abstract：:Numerous bacterial pathogens use type III secretion systems (T3SSs) or T4SSs to inject or translocate virulence proteins into eukaryotic cells. Several different reporter systems have been developed to measure the translocation of these proteins. In this study, a peptide tag-based reporter system was developed and use...

journal_title：Infection and immunity

authors： Garcia JT,Ferracci F,Jackson MW,Joseph SS,Pattis I,Plano LR,Fischer W,Plano GV

更新日期：2006-10-01 00:00:00

abstract：:The mechanism by which bacterial heat-stable enterotoxins (ST I STA) cause diarrhea in humans and animals has been linked to the activation of an intestinal membrane-bound guanylate cyclase. Guanylin, a recently discovered rat intestinal peptide, is homologous in structure to ST I and can activate guanylate cyclase pr...

journal_title：Infection and immunity

authors： Carpick BW,Gariépy J

更新日期：1993-11-01 00:00:00

abstract：:Pseudomonas aeruginosa utilizes a number of distinct pathways to secrete proteins that play various roles during infection. These include the type II secretion system, which is responsible for the secretion of the majority of exoproducts into the surrounding environment, including toxins and degradative enzymes. In co...

journal_title：Infection and immunity

authors： Lee VT,Smith RS,Tümmler B,Lory S

更新日期：2005-03-01 00:00:00

abstract：:In vitro experimentation indicates that periodontitis-associated bacteria contain potent polyclonal B-cell activators (PBA). We reasoned that if PBA were operative in vivo, plasma cells specific for nonoral antigens should be present in the inflamed gingival tissues, which are characterized by a plasma cell infiltrate...

journal_title：Infection and immunity

authors： Mallison SM 3rd,Szakal AK,Ranney RR,Tew JG

更新日期：1988-04-01 00:00:00

abstract：:Aspergillus fumigatus produces conidia that are highly dispersable and resistant to degradation. We have sought to analyze these properties by studying the rodlets which form the outer spore coat protein. Degenerate primers based on hydrophobins in other fungi were applied to genomic DNA from A. fumigatus in PCR. A pr...

journal_title：Infection and immunity

authors： Parta M,Chang Y,Rulong S,Pinto-DaSilva P,Kwon-Chung KJ

更新日期：1994-10-01 00:00:00

abstract：:Cell surface protein SSP-5 in the oral bacterium Streptococcus gordonii M5 binds human salivary agglutinin in a Ca(2+)-dependent reaction (D.R. Demuth, E.E. Golub, and D. Malamud, J. Biol. Chem. 265:7120-7126, 1990). The region of the gene encoding an N-terminal segment of a related polypeptide (SspA) in S. gordonii D...

journal_title：Infection and immunity

authors： Jenkinson HF,Terry SD,McNab R,Tannock GW

更新日期：1993-08-01 00:00:00

abstract：:Macrophage ribonucleic acid (RNA) synthesis is an important metabolic process intimately related to the function of these cells. Mouse peritoneal macrophage RNA was extracted with phenol in the presence of bentonite and electrophoresed on composite agarose-polyacrylamide gels. The pulse-chase technique was used to fol...

journal_title：Infection and immunity

authors： Soderberg LS,Tewari RP,Solotorovsky M

更新日期：1976-06-01 00:00:00

abstract：:Borrelia burgdorferi, an agent of Lyme disease, establishes persistent infection in immunocompetent animals and humans. Although the infection in humans can be cleared by antibiotic therapy, persistence in reservoir animals is necessary for the maintenance of the bacterium in the natural reservoir host⇔tick vector inf...

journal_title：Infection and immunity

authors： LaFrance ME,Pierce JV,Antonara S,Coburn J

更新日期：2011-08-01 00:00:00

abstract：:The morphology and pathology of cultured mouse glomeruli were examined at the cellular and subcellular levels after infection with a physiological isotonic L-form of Streptococcus pyogenes type 12 or exposure to streptococcal lipoteichoic acid. These changes, as viewed by light microscopy, were identical regardless of...

journal_title：Infection and immunity

authors： Tomlinson K,Leon O,Panos C

更新日期：1983-12-01 00:00:00

abstract：:Patent filarial infection is associated with the downregulation of parasite-specific immune reactivity. In the present study, the relationship between in vitro parasite antigen-specific humoral and cellular immune responsiveness was investigated in Brugia pahangi-infected jirds and in jirds immunized with soluble anti...

journal_title：Infection and immunity

authors： Prier RC,Lammie PJ

更新日期：1988-12-01 00:00:00

abstract：:Glucose metabolism and respiration of Candida albicans were compared under conditions which permitted either maximal filamentous or maximal yeast growth. Changes in metabolism were monitored by comparing the quantities of ethanol produced, CO2 evolved, and oxygen consumed. Filamenting cultures produced more ethanol an...

journal_title：Infection and immunity

authors： Land GA,McDonald WC,Stjernholm RL,Friedman L

更新日期：1975-07-01 00:00:00

abstract：:An experimental model of coxsackievirus B3 infection in newborn mice was utilized to examine the protective role of antiviral antibodies and an interferon inducer, polyinosinic acid-polycytidylic acid [poly(I:C)]. Subcutaneous administration to the infected mice of specific antiviral antibodies resulted in significant...

journal_title：Infection and immunity

authors： Cho CT,Feng KK,McCarthy VP,Lenahan MF

更新日期：1982-08-01 00:00:00

abstract：:Detailed structural studies were undertaken on five isolates of bovine rotavirus which showed variability in the migration patterns of their genome segments on electrophoresis in polyacrylamide gels. The individual genome segments of each isolate were characterized by partial digestion of terminally radiolabeled RNA w...

journal_title：Infection and immunity

authors： Clarke IN,McCrae MA

更新日期：1982-05-01 00:00:00