Abstract:
:Antimicrobial factors were analyzed in samples of whole saliva from 31 children, aged 0.8 to 3.8 years. When compared with the adult reference group, the children displayed similar levels of lysozyme, salivary peroxidase, and hypothiocyanite (OSCN-), whereas the amounts of immunoglobulins (isotypes A, G, and M), lactoferrin, myeloperoxidase, thiocyanate (SCN-), amylase, and protein were significantly lower than the adult values. The child's behavior during the collection period noticeably influenced the composition of the saliva. Children who were restless and crying during the collection had significantly more immunoglobulins, lysozyme, lactoferrin, salivary peroxidase, myeloperoxidase, and protein in their saliva samples, obviously due to the contamination of saliva mixed with nasal or lacrimal secretions. Therefore, the normal values for saliva could be determined for the noncrying children only. These salivary defense systems did not show any relation to the length of breast-feeding or to the previous history of antibiotic treatment. Thus, with the exception of lactoferrin and myeloperoxidase, the nonimmunoglobulin antimicrobial saliva systems studied here seem to be already at the adult level during early childhood, when the protective antibody systems are still immature.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Tenovuo J,Lehtonen OP,Aaltonen AS,Vilja P,Tuohimaa Pdoi
10.1128/IAI.51.1.49-53.1986subject
Has Abstractpub_date
1986-01-01 00:00:00pages
49-53issue
1eissn
0019-9567issn
1098-5522journal_volume
51pub_type
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journal_title:Infection and immunity
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更新日期:1986-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.49.3.700-708.1985
更新日期:1985-09-01 00:00:00
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pub_type: 杂志文章
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:1988-07-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/iai.71.6.3623-3627.2003
更新日期:2003-06-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:2004-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1998-10-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.33.3.950-953.1981
更新日期:1981-09-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.67.11.6198-6202.1999
更新日期:1999-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1128/iai.71.6.3551-3562.2003
更新日期:2003-06-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.5.2848-2856.2005
更新日期:2005-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00627-13
更新日期:2013-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.6.2639-2643.1994
更新日期:1994-06-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.44.2.394-400.1984
更新日期:1984-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.66.11.5477-5484.1998
更新日期:1998-11-01 00:00:00
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journal_title:Infection and immunity
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更新日期:2005-11-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:2009-11-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.58.7.2401-2403.1990
更新日期:1990-07-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.36.2.830-833.1982
更新日期:1982-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.24.2.571-572.1979
更新日期:1979-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1128/iai.68.3.1080-1085.2000
更新日期:2000-03-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:2003-09-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00645-16
更新日期:2016-12-29 00:00:00
abstract::To determine the protective efficacy of human hyperimmune globulin to Haemophilus influenzae type b disease in an infant rat model, we compared hyperimmune globulin containing 600 mug of anti-polyribophosphate (PRP) antibody per ml to conventional immune globulin containing 66 mug of anti-PRP antibody per ml. The hype...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.39.2.709-714.1983
更新日期:1983-02-01 00:00:00
abstract::The incidence of translocation of viable Escherichia coli C25 from the gastrointestinal tract to the mesenteric lymph nodes was compared in gnotobiotic mice colonized with only E. coli C25 and in gnotobiotic mice colonized with E. coli C25 plus the whole cecal flora from specific pathogen-free mice. The population lev...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.25.3.820-827.1979
更新日期:1979-09-01 00:00:00