Abstract：
:An outbreak of a canine influenza virus (CIV) H3N2 reassortant derived from pandemic (pdm) H1N1 and CIV H3N2 in companion animals has underscored the urgent need to monitor CIV infections for potential zoonotic transmission of influenza viruses to humans. In this study, we assessed the virulence of a novel CIV H3N2 reassortant, VC378, which was obtained from a dog that was coinfected with pdm H1N1 and CIV H3N2, in ferrets, dogs, and mice. Significantly enhanced virulence of VC378 was demonstrated in mice, although the transmissibility and pathogenicity of VC378 were similar to those of classical H3N2 in ferrets and dogs. This is notable because mice inoculated with an equivalent dose of classical CIV H3N2 showed no clinical signs and no lethality. We found that the PA and NS gene segments of VC378 were introduced from pdmH1N1, and these genes included the amino acid substitutions PA-P224S and NS-I123V, which were previously found to be associated with increased virulence in mice. Thus, we speculate that the natural reassortment between pdm H1N1 and CIV H3N2 can confer virulence and that continuous surveillance is needed to monitor the evolution of CIV in companion animals.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Lyoo KS,Na W,Yeom M,Jeong DG,Kim CU,Kim JK,Song Ddoi
10.1007/s00705-016-2868-xsubject
Has Abstractpub_date
2016-07-01 00:00:00pages
1915-23issue
7eissn
0304-8608issn
1432-8798pii
10.1007/s00705-016-2868-xjournal_volume
161pub_type
杂志文章abstract：:Mouse L-cells infected with UV-inactivated HSV could serve as suitable targets for monitoring H-2 restricted cytotoxicity mediated by HSV-immune T cells. Cytotoxic potential of immune T cells for H-2 compatible targets exposed to UV-inactivated HSV was enhanced if the later were pretreated with mouse interferon. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315679
更新日期：1978-01-01 00:00:00
abstract：:We constructed a recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2E delta 102). The production, processing and transportation of the recombinant protein in baculovirus-infected Spodoptera frugiperda (Sf9) cells and its immunogenic prop...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309465
更新日期：1994-01-01 00:00:00
abstract：:Human adenoviruses (Ad) 5 and 7 multiplied poorly in guinea-pig cell cultures as compared to HeLa cells. Ad 7 had a modified polypeptide composition with a major 43K component. This change persisted for up to 4 passages in HeLa cells. Ad 5 was not changed by passage in guinea-pig cells. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320631
更新日期：1980-01-01 00:00:00
abstract：:Thirty-seven clinical isolates of coxsackievirus (CV) serotypes B-1, B-3, B-4, and B-5 were inoculated into male SJL mice. Twelve strains resulted in minor abnormalities of glucose metabolism in one or more of six infected mice (Tables 1 and 2). Sequential infection of male SJL mice with CVB-3, CVB-4, and CVB-5 result...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309826
更新日期：1985-01-01 00:00:00
abstract：:Foot-and-mouth disease (FMD) is a highly contagious viral disease of transboundary importance. In India, since the launch of the FMD control programme, there has been a substantial increase in the vaccinated bovine population. In this scenario, there is a need for additional locally developed non-structural protein (N...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1973-3
更新日期：2014-07-01 00:00:00
abstract：:Multiple splicing sites exist in the RNA genome of the human immunodeficiency virus type 1 (HIV-1). In a screen for subgenomic forms of the HIV-1 genome that could be transferred to fresh cells by virus infection, we identified a novel spliced variant of HIV-1 RNA that uses a hitherto unknown splice acceptor site with...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718159
更新日期：1996-01-01 00:00:00
abstract：:Eighty-six varicella-zoster virus (VZV) strains of clades 1, 3 and 5, isolated from varicella and zoster patients in Germany, were analyzed by sequencing the glycoprotein E gene. Four novel non-synonymous and 10 novel synonymous mutations were detected. Of these, two synonymous (C513T, C885T) and two non-synonymous mu...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0864-0
更新日期：2011-03-01 00:00:00
abstract：:In vivo transfection by intramuscular injection with plasmids expressing the immunogenic proteins of microbial pathogens has considerable potential as a vaccination strategy against many pathogens of both man and animals. Here we report that weanling mice given a single intramuscular injection of 50 micrograms of a pl...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718332
更新日期：1996-01-01 00:00:00
abstract：:Styrian oil pumpkin seedlings (Cucurbita pepo L. subsp. pepo var. styriaca GREB: .) were treated for 48 h with 1 mM OTC (L-2-oxothiazolidine-4-carboxylic acid) in order to artificially increase cellular glutathione content. They were inoculated with zucchini yellow mosaic virus (ZYMV) 10 days later. The effects of OTC...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0880-2
更新日期：2007-01-01 00:00:00
abstract：:During aetiological study of diseased red clover (Trifolium pratense L.) using high throughput sequencing, a novel virus with a 10 kb genome divided into two segments was discovered. The virus, tentatively named red clover associated varicosavirus (RCaVV), is phylogenetically related to classifiable members of the gen...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3838-2
更新日期：2018-08-01 00:00:00
abstract：:Seven dsRNA segments were detected from a single Rhizoctonia solani strain HG81. From the full-length cDNA sequences of four smaller dsRNA segments, the genomes of two related partitiviruses, designated as Rhizoctonia solani partitivirus 3 (RsPV3) and RsPV4, were determined. The genomes of RsPV3 and RsPV4 are both com...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3627-3
更新日期：2018-02-01 00:00:00
abstract：:The complete genome sequences of two grapevine virus L (GVL) isolates collected from the wine grape cultivar Blanc du Bois (Vitis spp.: 'Florida D 6-148'×'Cardinal') in Texas were determined. The two genome sequences (excluding the polyA tail) were each 7594 nucleotide long and 99.7% identical to each other, but they ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04682-8
更新日期：2020-08-01 00:00:00
abstract：:Two strains of mouse cytomegalovirus (MCMV) propagated in mouse salivary glands could be distinguished in neutralization tests. Cell (mouse embryo fibroblast)-passaged virus of either strain was generally 10-20 times easier to neutralize than virus produced in mouse salivary glands. Evidence was obtained that mouse im...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315153
更新日期：1981-01-01 00:00:00
abstract：:Transgenic mice were produced by microinjection of a partial hepatitis C virus (HCV) genome sequence including the structural protein region, under the control of the albumin promoter and enhancer into fertilized eggs of C57BL/6 and BDF1 mice. Three founders carrying at least five copies of the transgene but not expre...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718169
更新日期：1996-01-01 00:00:00
abstract：:At necropsy, several dogs which died showing symptoms of hemorrhagic diarrhea, had significant lesions of the mucosa that were found especially in the duodenum and upper part of the small bowel. Study of ultrathin sections from the diseased mucosa revealed particles resembling parvoviruses in altered nuclei of cells o...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320586
更新日期：1979-01-01 00:00:00
abstract：:A novel bisegmented double-stranded RNA virus was identified in the mycoparasitic and opportunistic fungus Hypomyces chrysospermus. The RNA1 genome segment comprises 1866 bp and encodes an RNA-dependent RNA polymerase (RdRp). The RNA2 segment comprises 1822 bp and encodes a capsid protein. Phylogenetic analysis of the...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04359-x
更新日期：2019-10-01 00:00:00
abstract：:Chilo iridescent virus (CIV; IIV-6) is the type member of the genus Iridovirus (family Iridoviridae, large icosahedral cytoplasmic DNA viruses). CIV induces death and deformity in the cotton boll weevil, Anthonomus grandis, replicates productively in larvae of the cotton boll weevil, and significantly reduces laborato...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0945-x
更新日期：2007-01-01 00:00:00
abstract：:Few reports are available on HCV molecular epidemiology among IDUs in Eastern Europe, and none in Montenegro. The aim of this study was to investigate the HCV genotype distribution in Montenegro among IDUs and to perform Bayesian and evolutionary analysis of the most prevalent HCV genotype circulating in this populati...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3224-5
更新日期：2017-06-01 00:00:00
abstract：:There were three epidemic waves of human infection with avian influenza A (H7N9) virus in 2013-2014. While many analyses of the genomic origin, evolution, and molecular characteristics of the influenza A (H7N9) virus have been performed using sequences from the first epidemic wave, genomic characterization of the viru...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2872-1
更新日期：2016-08-01 00:00:00
abstract：:The competition between different types of aphthoviruses (foot-and-mouth disease virus [FMDV]) for receptor site utilization was determined. The Southern African Territories (SAT) types of FMDV absorbed poorly to BHK-21 cells as measured by a radioactivity binding assay but grew to relatively high titers on these cell...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320782
更新日期：1982-01-01 00:00:00
abstract：:Five avian paramyxoviruses of serotype 8 (APMV-8) were isolated during a study monitoring wild birds in Kazakhstan in 2013 and each was further characterized. The viruses were isolated from three White-fronted geese (Anser albifrons), one Whooper swan (Cygnus cygnus), and one Little stint (Calidris minuta). Before our...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3593-9
更新日期：2018-02-01 00:00:00
abstract：:Sendai virus given intravenously into CFLP mice produced dose-related suppression of the acute inflammation produced by carrageenan and 5-HT. The inhibition correlated with interferon levels in the blood, suggesting that interferon may account for the virus-induced anti-inflammatory effect. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314606
更新日期：1981-01-01 00:00:00
abstract：:The E1 nucleic acid sequence of rubella virus strain Judith (RJ) has been cloned into an E. coli expression vector LB03. The reactivity of the expressed unglycosylated antigen (E1J) was compared with its glycosylated counterpart in native virus (RJ) using rabbit and human sera. Rabbit antisera raised against RJ and E1...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317201
更新日期：1992-01-01 00:00:00
abstract：:Since the appearance of resistance to antiretroviral treatment is unavoidable, the host cell's transcription factor NF-kappaB is a novel HIV target. The goal of this study was to characterize the effect of two immunomodulators, curcumin (Cur) and sulfasalazine (Sul), with a protease inhibitor, indinavir (IDV), on HIV-...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0023-4
更新日期：2008-01-01 00:00:00
abstract：:The numbers of the carbohydrate side chains have been analyzed on a series of subtype 7 hemagglutinins of influenza A virus. The procedure employed involves growth of the virus in the presence of the trimming inhibitor N-methyl-1-desoxynojirimycin followed by controlled removal of the resulting mannose-rich oligosacch...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314433
更新日期：1987-01-01 00:00:00
abstract：:H9N2 avian influenza virus has caused huge economic loss for the Chinese poultry industry since it was first identified. Vaccination is frequently used as a control method for the disease. Meanwhile suspension culture has become an important tool for the development of influenza vaccines. To optimize the suspension cu...
journal_title：Archives of virology
pub_type： 临床试验,杂志文章
doi：10.1007/s00705-017-3460-8
更新日期：2017-10-01 00:00:00
abstract：:We investigated the in situ localization of the 50 kDa protein encoded by ORF2 of Apple chlorotic leaf spot virus (ACLSV) genome which is thought to be a movement protein. In immunogold electron microscopy of ACLSV-infected Chenopodium quinoa leaves, the 50 kDa protein was localized on plasmodesmata and nearby cytopla...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050660
更新日期：1999-01-01 00:00:00
abstract：:The genome of yam virus X (YVX), a new member of the genus Potexvirus from yam (Dioscorea trifida), was completely sequenced. Structural and phylogenetic analysis showed that the closest relative of YVX is nerine virus X. A prevalence study found YVX only in plants maintained in Guadeloupe and showed that it also infe...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2211-3
更新日期：2014-12-01 00:00:00
abstract：:The complete genome of O/Akesu/58 strain of foot-and-mouth disease virus (FMDV) was sequenced. The phylogenetic analysis revealed that it is not closely related to epidemic strains or previous strains compared with reference sequences (the identities of complete VP1 nucleotide sequences range from 77.5 to 84.0%). Its ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1041-y
更新日期：2007-01-01 00:00:00
abstract：:Wheat streak mosaic virus is a serious threat in wheat-producing countries. In Germany, the virus was first recorded in 2013 near Hoym. The complete sequence of isolate Hoym was obtained and compared to all other known complete WSMV sequences, including newly collected and sequenced isolates from France and Austria. P...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2422-2
更新日期：2015-07-01 00:00:00
