The virulence of Enterobacter cloacae and Serratia marcescens in experimental bladder infection in diabetic mice.

Abstract:

:Diabetic mice were significantly more susceptible than normal mice to bladder infection with Enterobacter cloacae or Serratia marcescens but not to intraperitoneal infection. Normal urine inhibited the growth of E. cloacae and S. marcescens, whereas urine from diabetic mice permitted multiplication. The addition of urea to urine from diabetic mice restored its antibacterial properties for E. cloacae and S. marcescens. We consider that the decreased urea content of the urine of diabetic mice was responsible for their increased susceptibility to bacterial infection of the bladder.

journal_name

J Med Microbiol

authors

Obana Y,Nishino T

doi

10.1099/00222615-30-2-105

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

105-9

issue

2

eissn

0022-2615

issn

1473-5644

journal_volume

30

pub_type

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